PatrickDLydenMD

Neurology • Los Angeles, CA

Vascular Neurology

Professor Physiology, Neuroscience, Neurology

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Office
1520 San Pablo St
Ste 3000
Los Angeles, CA 90033
Phone+1 323-442-5710

Fax+1 310-423-0148

Education & Training

University of California (San Diego) Medical CenterResidency, Neurology, 1982 - 1985
Scripps Mercy HospitalInternship, Transitional Year, 1981 - 1982
Baylor College of MedicineClass of 1981

Certifications & Licensure

CA State Medical License 1982 - 2025
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke Start of enrollment: 2003 Oct 01
Completed
Phase 1
The Intravascular Cooling in the Treatment of Stroke 2/3 Trial Start of enrollment: 2010 Jun 01
Terminated
Phase 2, Phase 3
Safety and Pharmacokinetics of Single and Multiple Ascending Doses of 3K3A-APC in Healthy Adult Volunteers Start of enrollment: 2012 Aug 01
Completed
Phase 1
Hypothermia in Acute Stroke With Thrombolysis Imaging Evaluation of Revascularization Start of enrollment: 2013 Feb 01
Terminated
Phase 2, Phase 3
Safety Evaluation of 3K3A-APC in Ischemic Stroke Start of enrollment: 2014 Oct 01
Completed
Phase 2
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Publications & Presentations

PubMed

Differential vulnerability among cell types in the neurovascular unit: Description and mechanisms.
Allison Brookshier, Patrick Lyden
Journal of Cerebral Blood Flow and Metabolism. 2025-01-01
1 citations
Before, during, and after: An Argument for Safety and Improved Outcome of Thrombolysis in Acute Ischemic Stroke with Direct Oral Anticoagulant Treatment.
Sanaz Monjazeb, Heather V Chang, Patrick D Lyden
Annals of Neurology. 2024-11-01
Effect of post thrombolytic intracerebral hemorrhage volume on 90-day outcomes in acute ischemic stroke patients.
Syed A Gillani, Xiaoyu Ma, Yilun Huang, Navpreet K Bains, Rami Fakih
Journal of Stroke and Cerebrovascular Diseases. 2024-11-01

Lectures

Therapeutic Hypothermia for Acute Ischemic Stroke
Los Angeles, CA - 2/13/2014
Thrombin Toxicity and the Neurovascular Unit
Los Angeles, CA - 2/13/2014

Press Mentions

New Noninvasive Device Promises Early Stroke Risk DetectionSeptember 29th, 2024
Fandango’s Flashback Friday — February 5February 5th, 2021
Don't Ignore Signs of Heart Attack During COVID-19April 30th, 2020
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Grant Support

Thrombin Mediated Cytotoxicity During Cerebral IschemiaNational Institute Of Neurological Disorders And Stroke2011–2012
Stroke TEAMNational Institute Of Neurological Disorders And Stroke2008–2011
Therapeutic Window For Acute Stroke Therapy (P50)National Institute Of Neurological Disorders And Stroke2008–2009
Therapeutic Window For Acute Stroke TherapyNational Institute Of Neurological Disorders And Stroke2003–2007
HypothermiaNational Institute Of Neurological Disorders And Stroke2003–2007
Core--Stroke TEAMNational Institute Of Neurological Disorders And Stroke2003–2007
Quantitation Of Early Vascular Leakage After StrokeNational Institute Of Neurological Disorders And Stroke2005–2006
Role Of Angiogenesis Following StrokeNational Institute Of Neurological Disorders And Stroke2004–2006
Angiogenesis Following StrokeNational Institute Of Neurological Disorders And Stroke2003
Gv150526 In Treatment Of Patients With Acute StrokeNational Center For Research Resources1999
Aptiganel Hydrochloride Versus Placebo In Acute Ischemic StrokeNational Center For Research Resources1998–1999
Study To Determine Effect Of Citicoline In Ischemic Stroke PatientsNational Center For Research Resources1997–1999
Gv150026 In Treatment Of Patients With Acute StrokeNational Center For Research Resources1998
Gv150526a In Treatment Of Acute StrokeNational Center For Research Resources1997
Phase IIB Randomized Controlled Study Of Tissue PlasminNational Institute Of Neurological Disorders And Stroke1994–1995
Phase II-B Randomized Controlled Study Of Tissue PlasminNational Institute Of Neurological Disorders And Stroke1990–1993
Multifocal Cerebral IschemiaNational Institute Of Neurological Disorders And Stroke1989–1993