PatrickAndrewBrownMD

Pediatric Hematology & Oncology • Baltimore, MD

Pediatric Hematologic Oncology

Associate Professor of Oncology, Assistant Professor of Pediatrics, Johns Hopkins University School of Medicine; Director, Pediatric Leukemia and Lymphoma Program

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Office
600 N Wolfe St
Baltimore, MD 21287
Phone+1 410-955-6132

Fax+1 410-955-8897

Education & Training

Johns Hopkins UniversityFellowship, Pediatric Hematology/Oncology, 2001 - 2004
Johns Hopkins UniversityResidency, Pediatrics, 1998 - 2001
Medical University of South CarolinaClass of 1998

Certifications & Licensure

MD State Medical License 2001 - 2022

Clinical Trials

Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors Start of enrollment: 2011 Feb 09
Completed
Phase 1, Phase 2
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Start of enrollment: 2010 Oct 01
Terminated
Phase 1, Phase 2
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. Start of enrollment: 2013 Aug 20
Completed
Phase 2
A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL Start of enrollment: 2014 Jan 06
Completed
Early Phase 1
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Publications & Presentations

PubMed

205 citations
Treatment of pediatric acute lymphoblastic leukemia.
Stacy L. Cooper, Patrick A. Brown
Pediatric Clinics of North America. 2015-02-01
41 citations
Phase II Trial of Inotuzumab Ozogamicin in Children and Adolescents With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia: Children's Oncology Group Protocol...
Maureen M O'Brien, Lingyun Ji, Nirali N Shah, Susan R Rheingold, Deepa Bhojwani
Journal of Clinical Oncology. 2022-03-20
61 citations
How I treat infant leukemia
Patrick A. Brown, Rob Pieters, Andrea Biondi
Blood. 2019-01-17

Abstracts/Posters

A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+ B-Acute Lymphoblastic Leukemia (B-ALL): Results fro...
Patrick A. Brown, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Sorafenib in Combination with Standard Chemotherapy for Children with High Allelic Ratio FLT3/ITD+ AML Improves Event-Free Survival and Reduces Relapse Risk: A Report ...
Patrick A. Brown, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Single Cell Sequencing Reveals Heterogeneity of Gene Expression in KMT2A Rearranged Infant ALL at Relapse Compared to Diagnosis
Patrick A. Brown, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

How I Treat Infant Leukemia
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019

Press Mentions

Johns Hopkins University: Young Johns Hopkins Children’s Center Patient Shows Superhero Powers in Fight with CancerSeptember 7th, 2021

External Links

Johns Hopkins Physicianshttp://www.hopkinsmedicine.org/patrick-brown