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Office
55 Park Street
Yale Cancer Center
New Haven, CT 06519Phone+1 203-785-4095
Summary
- Pat LoRusso brings more than 25 years of expertise in medical oncology, drug development, and early phase clinical trials. Prior to her Yale appointment, she served in numerous leadership roles at Wayne State University’s Barbara Karmanos Cancer Institute, most recently as director of the Phase I Clinical Trials Program and of the Eisenberg Center for Experimental Therapeutics.
Education & Training
- Detroit Medical Center/Wayne State UniversityFellowship, Hematology and Medical Oncology, 1985 - 1988
- Michigan State University College of Osteopathic MedicineClass of 1981
Certifications & Licensure
- CT State License 2014 - 2025
- MI State License 1981 - 2015
- AOA Board of Internal Medicine Hematology/Oncology
- AOA Board of Internal Medicine Internal Medicine
Clinical Trials
- Pyrazoloacridine in Treating Women With Metastatic Breast Cancer Start of enrollment: 1994 Feb 01
- KRN5500 in Treating Patients With Metastatic Solid Tumors Start of enrollment: 1997 May 01
- Fenretinide in Treating Patients With Solid Tumors Start of enrollment: 1998 May 01
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Publications & Presentations
PubMed
- 412 citationsPhase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.Patricia LoRusso, Charles M. Rudin, Josina C. Reddy, Raoul Tibes, Glen J. Weiss
Clinical Cancer Research. 2011-04-15 - 35 citationsTargeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs.Shin Ogita, Patricia LoRusso
Targeted Oncology. 2011-05-06 - 91 citationsA phase I dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors.Renata Ferrarotto, Gail Eckhardt, Amita Patnaik, Patricia LoRusso, Leonardo Faoro
Annals of Oncology. 2018-07-01
Press Mentions
- AACR Cancer Progress Report: Big Strides and Big GapsSeptember 26th, 2024
- AACR Warns of Threat to Cancer Progress, Highlights Advances in Annual ReportSeptember 23rd, 2024
- New Report Highlights Overlooked Cancer Risk Factor: AlcoholSeptember 18th, 2024
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Grant Support
- Early Clinical Trials Of New Anti-Cancer AgentsNational Cancer Institute2008–2012
- Correlative Studies For NCI Study#7916: Phase I Clinical Trial Of Intravenous FAUNational Cancer Institute2009–2010
- Correlative Studies For NCI Study #7977: Phase I Trial Of ABT-888 PLUS IrinotecanNational Cancer Institute2008–2009
- Phase I Clinical Trials Of New Anticancer AgentsNational Cancer Institute2003–2007
- Foreign Accrual For U01ca62487 2006 Load Phase I U01National Cancer Institute2006
- Phase I Trials Of Anticancer AgentsNational Cancer Institute1998–2002
- Phase I Trials Of New Anticancer AgentsNational Cancer Institute1996–1997
- New Drug Combinations For Breast CancerNational Cancer Institute1995–1996
Professional Memberships
- Member
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