PatriciaSuzanneLathamMDEdD

PubMed

• Aldehydes alter TGF-β signaling and induce obesity and cancer.
  Xiaochun Yang, Krishanu Bhowmick, Shuyun Rao, Xiyan Xiang, Kazufumi Ohshiro
  Cell Reports. 2024-09-24
• 2 citations
  Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis.
  Xiyan Xiang, Krishanu Bhowmick, Kirti Shetty, Kazufumi Ohshiro, Xiaochun Yang
  Genes & Cancer. 2024-01-01
• 3 citations
  TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer.
  Ashutosh S Yende, Emily C Williams, Andrew Pletcher, Alexandra Helfand, Helen Ibeawuchi
  Oncogene. 2023-04-01

Journal Articles

• Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis  
  Ahmed U, Latham PS, Oates PS, World J. Gastroenterol., 1/14/2012
• Hepatitis C Virus Infection, Opiate Use and the Prevalence and Incidence of Diabetes Mellitus in the Women's Interagency HIV Study  
  Howard AA, Hoover DR, Anastos K, Wu X, Shi Q, Augenbraun M, Cohen M, Cole SR, Kovacs A, Latham PS, Tien PC, J. Acquired Immunodef. Syndromes, 1/1/2010
• Assessing the process of patient flow in the outpatient clinics of a medical center: An organizational diagnosis  
  Latham PS, Timblo A, Hodgins A, Tatum J, Cseh M, Proc. Acad. Human Resource Dev., 1/1/2006
• Protective effects of flax meal against hypercholesterolemia and hyper-triglyceridemia in rats  
  W.M.N. Ratnayake, G.S. Gilani, Sam J. Bhathena, Ali A. Ali, Christian Haudenschild, Patricia Latham, Tedine Ranich, Ali I. Mohamed, Carl T. Hansen, and Manuel T. Velas..., J. Am. Coll. Nutr., 1/1/2003
• Dietary flaxseed meal is more protective than soy protein concentrate against hypertriglyceridemia and steatosis of the liver in an animal model of obesity  
  Bhathena SJ, Ali AA, Haudenschild C, Latham PS, Ranich T, Mohamed AI, Hansen CT, Velasquez MT, J. Am. Coll. Nutr., 1/1/2003
• Intestinal alkalinization as a possible preventive mechanism in irinotecan (CPT-11)-induced diarrhea  
  Ikegami T, Linan H, Latham PS, Kobayashi K, Ceryak S, Matsuzaki Y, Bouscarel B, Cancer Research, 1/1/2002
• Taskforce on Training in Hepatology  
  Boyer TD, Bloomer JR, Everson GT, Gerber M, Gitlin N, Heathcote J, Henderson JM, Latham P, Lindor KD, Lindsay KL, Sampliner RA, Schiff ER, Wilson RA, Gastroenterol, 1/1/1996
• Effects of tryptophan related compounds on nuclear regulatory control Possible role in the Eosinophilia-Myalgia Syndrome  
  Sidransky H, Verney E, Latham P, Schwartz A, Adv Exp Med Biol, 1/1/1996
• AIDS-associated salivary gland pathology: An autopsy survery of 60 cases  
  Wagner RP, McPherson MJ, Latham PS, Orenstein JM, Clinical Infectious Disease, 1/1/1996
• Effect of 3-pehylamino-L-alanine on tryptophan binding to rat hepatic nuclear envelopes  
  Sidransky H, Verney E, Cosgrove JW, Latham PS, Toxicol, 1/1/1994
• Indolic compounds affect tryptophan binding to rat hepatic nuclei  
  Sidransky H, Verney E, Cosgrove JW, Latham, PS, Schwartz, AM, J Nutr, 1/1/1994
• Studies with 1,1'-ethilidenebis(tryptophan), a contaminant associated with L-tryptophan implicated in the Eosinophilia-Myalgia Syndrome  
  Sidransky H, Verney E, Cosgrove JW, Latham PS, Mayeno AN, Toxicol Applied Pharmacol, 1/1/1994
• Antibody-facilitated macrophage killing of Trypanosoma musculi is an extracellular process as studied in several variations of an in vitro analytical system  
  Albright JW, Stewart K, Latham PS, Albright J, J Leukocyte Biol, 1/1/1994
• Effect of macrophage source and activation on susceptibility in an age dependent model of murine hepatitis caused by a Phlebovirus, Punta Toro  
  Latham PS and Sepelak SB, Arch Virol, 1/1/1992
•  
  Latham PS, Sepelak SB, Pifat DY, Smith JF, J Med Virol, 1/1/1991
• Herpes Simplex virus hepatitis in pregnancy: two patients successfully treated with acyclovir  
  Klein NA, Mabie BC, Shaver D, Latham PS, Riely, CA, Gastroenterology, 1/1/1991
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  Crawford EK, Latham PS, Shah EM, Hasday JD, Cancer Research, 1/1/1990
• Expression of Human Immunodeficiency Virus-long terminal repeat in the human promonocyte cell line, U937: Effect of endotoxin and cytokines  
  Latham PS, Lewis AM, Varesio L, Pavlakis GN, Felber BK, Ruscetti FW, Young HA, Cellular Immunol, 1/1/1990
• Functional and structural changes in the parotid glands of alcoholic cirrhotic patients  
  Dutta SK, Dukehart M, Narang A, Latham PS, Gastroenterology, 1/1/1989
• Reyes Syndrome: Are adults big children? (Invited Review)  
  Latham PS, Hepatol, 1/1/1988
• The Role of hepatocytes and sinusoidal cells in the pathogenesis of viral hepatitis  
  Latham PS, International Review of Cytology, 1/1/1988
• Acute fatty liver of pregnancy revisited  
  Riely CA, Latham PS, Romero R, Duffy TP, Ann Int Med, 1/1/1987
•  
  Mathieson RD, Sampliner RE, Latham PS, Rogers EL, Alter MJ, Am J Clin Pathol, 1/1/1986
• Vitamin A deprivation in hamsters: Correlations between tracheal epithelial morphology and serum/tissue levels of vitamin A  
  Strum JM, Latham PS, Schmidt ML, McDowell EM, Virchows Arch (Cell Pathol), 1/1/1985
• Achalasia associated with squamous cell carcinoma of the esophagus: A case report  
  Rock LA, Latham PS, Hankins JR, Nasrallah SM, Am J Gastroenterol, 1/1/1985
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Books/Book Chapters

• Essentials Of Public Health Biology 
  Chapter: Latham PS 
  Latham PSEditors: Battle, C..Jones & Bartlett, Boston, MA2009
• Mononuclear Phagocytes in Cell Biology 
  Chapter: Activation of macrophages and monocytes by interferon-gamma and IL2 
  Page 119 - 146Varesio L, Cox, GW, Pulki K, Musso, T, Latham, PS, Gusella, LG, Espinoza-Delgado IEditors: J. Klostergaard and D. Lopez-Berestein.CRC Press, Boston, MA1993
• Cells of the Hepatic Sinusoid Vol. III 
  Page 312 - 314Latham PS, Pilaro AM, Echeagary PL, Varesio LMEditors: A Kirn, DL Knook. E Wisse.Kupffer Cell Foundation, The Netherlands1991
• Monographs on Pathology of laboratory Animals-Hemopoietic System 
  Chapter: Identification and functional characteristics of monocytes/macrophages. 
  Page 114 - 121Varesio L, Gonda M, Latham PEditors: TC Jones, JM Ward, U Mohr, and RD Hunt.New York, NY1990
• Gastroenterology-A Concise Textbook 
  Chapter: Acute hepatitis. 
  Latham PSEditors: Iber FL and Baum R.Elsevier Biomedical Press, New York, NY1987
• Gastroenterology-A Concise Textbook 
  Chapter: Chronic hepatitis and cirrhosis. 
  Latham PSElsevier Biomedical Press, New York, NY1987
• Diseases of the Liver 
  Chapter: The ultrastructural investigation of liver disease. 
  Phillips MJ, Latham PSEditors: Schiff L and Schiff ER.Lippincott Publ., Philadelphia, PAEdition 5th,1987
• Immunobiology and Immunopharmacology of Bacterial Endotoxins 
  Chapter: Endotoxin toxicity to hepatocytes in vitro-modulation by macrophages, (peer-reviewed proceedings of a symposium). 
  Page 151 - 158Latham PS and Sepelak SBEditors: A Szentivanyi and H Friedman.Plenum Press, New York, NY1986
• Principles of Medical Therapy in Pregnancy 
  Chapter: Liver diseases of pregnancy. 
  Latham PSEditors: N Gleicher.Plenum Publ, New York, NY1986
• Pathological Physiology-Mechanisms of Disease 
  Chapter: Normal and pathologic physiology of the liver. 
  Iber FL and Latham PSEditors: Sodeman WA and Sodeman TM.WB Saunders, Philadelphia, PA1985
• Diseases of the Liver 
  Chapter: The ultrastructural investigation of liver liver disease. 
  Phillips MJ, Latham PSEditors: Schiff L and Schiff ER.Lippincott Publ., Philadelphia, PAEdition 4th,1982
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Abstracts/Posters

• Medical Students in Microscopic Anatomy and Pathology Laboratories: Design of an E-Learning Histology and Histopathology Atlas as an Evolving Response to Interdiscipli...
  Davis, MS, Mills A., Karcher D, Latham P, Krum J, Jurjus RA, Annual Meeting of Experimental Biology, Boston, MA, 1/28/2015
• The Impact of Instructional Design in a Case-Based, Computer-Assisted Instruction (CAI) Module on Learning Liver Pathology in a medical school Pathology course.
  Latham PS and Cseh M, 20th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/1/2015
• Medical Students in Microscopic Anatomy and Pathology Laboratories: Design of an E-Learning Histology and Histopathology Atlas as an Evolving Response to Interdiscipli...
  Latham PS, 20th Annual Research Day, George Washington Univ Med Center, 1/1/2015
• Associations of Liver Biopsy Glycogenated Nuclei with Diabetes Mellitus (DM) and Steatosis in Morbid Obesity (MO).
  Arab SE, Latham PS, 20th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/1/2015
• Development of a Method Quantifying Fibrosis in Wedge Liver Biopsies with Non-Alcoholic Fatty Liver Disease (NAFLD).
  Alrajjal A, Arab SE, Kammili L, Latham PS, 20th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/1/2015
• Non-invasive Tests for Liver Fibrosis in Patients with Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) co-infection and Use of Sirius Red as a Quantitat...
  Tashkandi H, Hammond B, Kammili L, Ding R, Latham P, 19th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/2/2014
• Non-invasive tests for liver fibrosis in patients with Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) co-infection.
  Hammond B, Alqatari M, Latham P, 18th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/3/2013
• Hepatic fibrosis and immune phenotypes vary by HCV viremia in HIV infection-A Women's Interagency HIV Study.
  Desai SN, Dodge J, Landay A, Glesby M, Latham P, Villacres M, French A, Ameli N, Greenblatt R, Peters GM, 19th Conference on Retroviruses and Opportunistic Infections (CROI), Atlanta, 1/1/2013
• Resistin Expression Correlates with Steatohepatitis in Obese Patients.
  Edwards C, Hindle K, Latham PS, Fu S, Brody F, Am. College of Surgeons, Surg Endosc., American College of Surgeons 96th Annual Clinical Congress, Washington, DC, October 5, 2010, 1/1/2013
• HCV viremia affects immune phenotypes in elite controllers of HIV infection: a Women's Interagency HIV Study (WIHS).
  Desai S, Landay A, Glesby M, Edlin B, Latham P, Villaacres M, French A, Amelil N, Greenblatt R, Peters M, XIX International AIDS Conference, Washington, DC, 1/22/2012
• An Introduction to Team Based Learning (TBL) for Medical Students in Pathology.
  Latham PS, Goldman E, 16th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/23/2011
• An Introduction to Team Based Learning (TBL) for Medical Students in Pathology, using Virtual Slides (VS) with a Focus on Concepts of Autopsy Practice and the Patholog...
  Latham PS, Goldman E, Northeast Group on Education Affairs (NEGEA) of the AAMC, Washington, DC, 1/11/2011
• Fatty Acid Composition in the Liver of SHR/N-corpulent Rat, a Genetic Animal Model of Obesity and Type-2 Diabetes Mellitus: Role of Dietary Protein Source.
  Rowland C, King M, Bhathena S, Latham PS, Velasquez MT, 14th Annual Research Day, George Washington Univ Med Center, Washington, DC, 1/1/2009
• PKCalpha, p38 MAPK and FXR play a key role in the regulation of COX-2 mediated inhibition of human hepatic stellate cell proliferation by bile acids.
  Meng J, Nguyen A, Miyazaki T, Latham PS, Rojkind M, Afram J, Lin P, Bouscarel B, Hepatology, Am Assoc Study of Liver Dis, Annual Meeting, San Francisco, CA, 1/1/2008
• Rapid Cardiac Failure and Death Due to Giant Cell Myocarditis Associated with Myositis, Thymoma, and Myasthenia Gravis.
  Tryggestad (Codispotti) K, Jones R, Latham PS, Archives of Pathol. Lab. Med., College of American Pathology, Annual Meeting, Chicago, IL, 1/30/2007
• CDCA regulates cell proliferation and COX-2 protein expression through activation of both PKCa and p38 MAPK in human stellate cells.
  Meng JP, AlRashid M, Krilov L, Johston H, Latham P, Lin PP, Aphram JD, Rojkind M, Bouscarel B, Gastroenterology, Digestive Disease Week, Washington, DC, 1/22/2007
• FXR plays a key role in the regulation of COX-2 expression by the bile acid CDCA in human stellate cells.
  Meng JP, AlRashid M, Krilov L, Johston H, Latham P, Lin PP, Aphram JD, Rojkind M, Bouscarel B, Gastroenterology, Digestive Disease Week, Washington, DC, 1/22/2007
• Supporting the Role of Faculty in Transformational Curriculum Change.
  Latham PS, American Medical Colleges-Northeast Group on Educational Affairs, Stony Brook, NY, 1/8/2007
• Bile acid regulation of COX-2-dependent cell proliferation in both human fibroblasts and stellate cells.
  Meng JP, Krilov L, Rashid A, Rojkind M, Nsien E, Afram J, Brody F, Lin P, Latham P, Carter C, Drenon E, Bouscarel B, AACR Meeting, Am Assoc Cancer Res, Washington, DC, 1/1/2006
• Nonalcoholic Steatohepatitis (NASH) in patients with morbid obesity is commonly associated with normal liver enzymes.
  Latham PS, Borum ML, Nsien EE, Afram JD, Hepatology, Annual Meeting of the Am Assoc Study of Liver Dis, Boston, MA, 1/1/2003
• Development of a rodent soft tissue model of infection: An application towards the study of the anti-inflammatory potential of simvastatin in infectious disease.
  Friedman L, Malik A, Yoon B, Kan V, Latham P, Simon G, Liappis A, GWY 7th Annual Research Day, 1/1/2003
• Intestinal alkalinization as a possible preventive mechanism in irinotecan (CPT-11)-induced diarrhea.
  Ikegami T, Linan H, Latham PS, Kobayashi K, Ceryak S, Matsuzaki Y, Bouscarel B, Gastroenterology, Digestive Disease Week, Atlanta, GA, 1/1/2001
• The impact of carbon dioxide on monocyte-macrophage cytotoxicity.
  Jackson PG, Czerniach DR, Iglesias AR, Evans SRT, Latham PS, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Annual Meeting, MO, 1/1/2001
• Carbon dioxide impairs cytokine secretion and phagocytosis in human macrophages.
  Jackson PG, Czerniach DR, Iglesias AR, Evans SRT, Sackier JM, Latham PS, GWU 5th Annual Research Day, 1/1/1999
• Carbon dioxide impairs human macrophage cytokine secretion and phagocytosis.
  Jackson PG, Czerniach DR, Iglesias AR, Evans SRT, Sackier JM, Latham PS, Annual Meeting of the American College of Surgeons, San Francisco, CA, 1/1/1999
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Lectures

• "Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma" 
  Washington, DC - 1/21/2015
• "Use of Virtual Slides for Pathology Case Studies in Medical Education" 
  Seattle, WA - 1/14/2010
• "Virtual Microscopy with Digital Slides: Now, How, Wow" 
  New Orleans, LA - 1/10/2010
• "The Role of Inflammation in Toxicology" 
  Washington, DC - 1/23/2007
• "Role Modeling: Pathology Residents as Teachers in Undergraduate Medical Education" 
  Colorado Springs, CO - 1/19/2007
• Assessing the process of patient flow in the outpatient clinics of a medical center: An organizational diagnosis. 
  Columbus, OH - 1/25/2006
• "The Virtual Autopsy Project-web-based Pathology case studies" 
  Mont Tremblant, Quebec, Canada - 1/28/2005
• "The role of macrophages in chronic hepatitis" 
  Memphis, TN - 1/3/1993
• "The role of macrophages in a model of experimental viral hepatitis" 
  University of California San Francisco Medical System, San Francisco, CA - 1/15/1991
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  Tucson, AZ - 1/1/1990
• Endotoxin (LPS) toxicity to hepatocytes (H) in vitro-modulation by macrophages (M). 
  Tampa, FL - 1/1/1985
• "TPN (total parenteral nutrition)-Associated Liver Disease" 
  Baltimore, MD - 1/1/1984
• "Evaluation of Patients with Chronic Liver disease" 
  Baltimore, MD - 1/1/1984
• "New Insights in Chronic Liver Disease" 
  Baltimore, MD - 1/1/1983
• "Alpha-antitrypsin Disease" 
  Baltimore, MD - 1/1/1982
• "Cytology Assessment in the Evaluation of Liver disease" 
  Baltimore, MD - 1/1/1982
• Membranous Glomerulonephropathy in children. 
  St. Johns, Newfoundland - 1/1/1980
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Other

• The impact of instructional design in a case-based, computer-assisted instruction module on learning liver pathology in a medical school pathology course. 
  Latham, Patricia S, Ed.D. dissertation, The George Washington University
  http://search.proquest.com/docview/1654779435?accountid=11243
  1/1/2015
• The Virtual Autopsy Project (Autopsy Case Studies for Students of Pathology for Autopsy Case Studies for Students of Pathology for) 
  Latham PS
  https://inside.gwumc.edu/pathology/virtualautopsy/