Overview of Dr. Becker
Pamela S. Becker, MD, PhD is a physician scientist at City of Hope in the Division of Leukemia, Department of Hematology and Hematopoietic Cell Transplantation.
Her research studies include the mechanism of cell adhesion-mediated chemotherapy resistance in AML, hematopoietic stem cell gene therapy for an inherited disorder of DNA repair, and precision therapy for AML, multiple myeloma, CML and all hematologic malignancies based on high-throughput drug sensitivity testing including correlation of mutations and gene expression with drug sensitivity.
Becker earned a medical degree and PhD at Harvard Medical School in the Harvard-MIT Health Sciences and Technology Program in Boston. She completed an internal medicine internship and residency at Beth Israel Hospital/Harvard Medical School in Boston and a fellowship in hematology at Yale University School of Medicine.
She has a long career as a translational researcher and is an author on over 200 peer-reviewed and other publications in the fields of inherited blood disorders, hematologic malignancies, and hematopoietic cell transplantation.
Office
City of Hope
1500 E. Duarte Rd
Duarte, CA 91010
Education & Training
- Yale-New Haven Medical CenterFellowship, Hematology and Medical Oncology, 1988 - 1991
- Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1986 - 1988
- Harvard Medical SchoolClass of 1986
Certifications & Licensure
- WA State Medical License 2003 - 2026
- CA State Medical License 2019 - 2025
- MA State Medical License 1993 - 2005
- CT State Medical License 1988 - 2003
- American Board of Internal Medicine Hematology
Clinical Trials
- Gene Therapy for Fanconi Anemia Start of enrollment: 2012 Feb 22
- Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome Start of enrollment: 2013 May 21
- Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay Start of enrollment: 2013 Aug 02
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Publications & Presentations
PubMed
- 8 citationsComparative analysis of flow cytometry and morphology for the detection of acute myeloid leukaemia cells in cerebrospinal fluidKeith R. Loeb, Sindhu Cherian, Pamela S. Becker, Roland B. Walter, John M. Pagel
British Journal of Haematology. 2016-01-01 - 132 citationsA machine learning approach to integrate big data for precision medicine in acute myeloid leukemiaSu-In Lee, Safiye Celik, Benjamin A. Logsdon, Scott M. Lundberg, Timothy J. Martins
Nature Communications. 2018-01-03 - 38 citationsA Phase Ib Study of Onvansertib, a Novel Oral PLK1 Inhibitor, in Combination Therapy for Patients with Relapsed or Refractory Acute Myeloid LeukemiaAmer M. Zeidan, Maya Ridinger, Tara L. Lin, Pamela S. Becker, Gary J. Schiller
Clinical Cancer Research. 2020-09-30
Journal Articles
- Phase 1/2 Trial of Cladribine, High-Dose Cytarabine, Mitoxantrone, and G-CSF with Dose-Escalated Mitoxantrone for relapsed/refractory Acute Myeloid Leukemia or Other H...Kelda M Gardner, Vivian G Oehler, Heather A Smith, Anna B Halpern, Paul C Hendrie, Sarah A Buckley, Roland B Walter, Pamela S Becker, Ryan D Cassaday, Asma Anwar, Bart..., Haematologica
- Long Term Follow-up of Tandem Autologous-Allogeneic Hematopoietic Cell Transplantation for Multiple MyelomaParameswaran Hari, Brenda M Sandmaier, Pamela S Becker, Leona Holmberg, Damian J Green, Peter A McSweeney, David G Maloney, Thomas R Chauncey, Haematologica
- Novel Lineage Depletion Preserves Autologous Blood Stem Cells for Gene Therapy of Fanconi Anemia Complementation Group ALauri M Burroughs, Pamela S Becker, Haematologica
Abstracts/Posters
- Treatment of Refractory Acute Myeloid Leukemia and High-Grade Myelodysplastic Syndrome: Implications of Further Care at an Academic Center Versus Community SettingPamela S. Becker, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- Outcomes after Stem Cell Transplant in Older Patients with Acute Myeloid Leukemia Treated with Venetoclax-Based TherapiesClinically Relevant AbstractPamela S. Becker, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- Safety, Efficacy and Biomarker Analysis of a Phase 1b/2 Study of Onvansertib (ONV), a Polo-like Kinase 1 (PLK1) Inhibitor, in Combination with Low-Dose Cytarabine (LDA...Pamela S. Becker, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures
- A Multi-Omic Precision Medicine Clinical Trial in Acute Leukemia61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Machine Learning in Hematology61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Dose-Adjusted Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) Is Active and Well-Tolerated in Adults with Newly-Diagnosed Acute Lympho...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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Press Mentions
- BBI ‘Catalytic Collaboration’ Grant Leads to ‘Extraordinary’ Progress in Research for Directing Treatment of Multiple Myeloma PatientsMay 28th, 2021
Insurance Accepted
- Aetna Choice POS II
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ODS Network
Premera BCBS Heritage & Heritage Plus 1
Providence Health System Personal Option
Regence Washington - Preferred Provider Network
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO - Please verify your coverage with the provider's office directly when scheduling an appointment
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