
Ottavio Valerio Vitolo MD
Neuropsychiatry
Neuropsychiatrist, Massachusetts General Hospital
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15 Parkman StWACC 815Boston, MA 02114
Phone+1 617-724-5600
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Summary
- I am a board-certified psychiatrist and neuropsychiatrist with extensive experience across academic medicine, clinical research, and the biotechnology industry. I serve as a neuropsychiatrist at Massachusetts General Hospital and a Lecturer in Psychiatry at Harvard Medical School.
I specialize in the treatment of complex neuropsychiatric and neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, traumatic brain injury, and long COVID. My clinical focus includes cognitive, emotional, and behavioral symptoms across the neurological-psychiatric spectrum.
I bring additional expertise in translational medicine, clinical trial design, and biomarker development, shaped by leadership roles in the biotech and pharmaceutical sectors.
I am also the founder of New England Brain Health, a private practice offering personalized neuropsychiatric care and brain health optimization programs for individuals seeking data-driven, holistic, and precision-based care.
Education & Training
- Harvard Medical SchoolM.M.Sc., Translational Medicine, 2010 - 2012
- Brigham and Women's HospitalBehavioral Neurology and Neuropsychiatry, 2008 - 2009
- Washington University/B-JH/SLCH ConsortiumResidency, Psychiatry, 2004 - 2008
- Sapienza University of RomeClass of 1998
Certifications & Licensure
- MA State Medical License 2008 - 2025
- American Board of Psychiatry and Neurology Psychiatry
- United Council for Neurologic SubspecialtiesBehavioral Neurology and Neuropsychiatry
Clinical Trials
- Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression Start of enrollment: 2012 Apr 01
Publications & Presentations
PubMed
- 1 citations"When Will All of This End?": A 65-Year-Old Man With Amyotrophic Lateral Sclerosis and Psychiatric Distress.Ethan G Lester, Ottavio V Vitolo, Alice Flaherty, Yvan Beaussant, Margaret Cramer
The Journal of Clinical Psychiatry. 2023-12-13 - 1 citationsResilient together-ALS: leveraging the NDD transdiagnostic framework to develop an early dyadic intervention for people with amyotrophic lateral sclerosis and their in...Christina L Rush, Ethan G Lester, Heena Manglani, Emily Woodworth, Ottavio Vitolo
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2023-06-22 - 54 citationsREL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial.Maurizio Fava, Stephen Stahl, Luca Pani, Sara De Martin, Marco Pappagallo
The American Journal of Psychiatry. 2022-02-01
Press Mentions
- Relmada Therapeutics Stock Soars on Phase 2 Depression Study ResultsOctober 15th, 2019
- Relmada Therapeutics Announces Publication of REL1017 Phase 1 Studies ResultsApril 16th, 2019
Committees
- Member, Target ALS - Independent Review Committee 2024 - Present
Professional Memberships
- Fellow
- American Neuropsychiatric AssociationFellow
- American Society of Clinical PsychopharmacologyMember
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