OscarJoeHinesMD

PubMed

• 147 citations
  Risk of Malignancy in Resected Cystic Tumors of the Pancreas ≤3 cm in Size: Is it Safe to Observe Asymptomatic Patients? A Multi-institutional Report
  Cheong J. Lee, James M. Scheiman, Michelle A. Anderson, Oscar J. Hines, Howard A. Reber
  Journal of Gastrointestinal Surgery. 2008-02-01
• 53 citations
  Downstaging Chemotherapy and Alteration in the Classic Computed Tomography/Magnetic Resonance Imaging Signs of Vascular Involvement in Patients With Pancreaticobiliary...
  Timothy R. Donahue, William H. Isacoff, O. Joe Hines, James S. Tomlinson, James J. Farrell
  Archives of Surgery. 2011-07-18
• 107 citations
  Circulating tumour cells as a biomarker for diagnosis and staging in pancreatic cancer
  Jacob S. Ankeny, Colin M. Court, Shuang Hou, Qingyu Li, Min Song
  British Journal of Cancer. 2016-06-14

Journal Articles

• A Prognostic Scoring System for the Prediction of Metastatic Recurrence Following Curative Resection of Pancreatic Neuroendocrine Tumors  
  Paul A Toste, Shonan Sho, Colin M Court, Joseph R Pisegna, Oscar J Hines, Howard A Reber, David W Dawson, Michael Lewis, James S Tomlinson, Timothy R Donahue, Journal of gastrointestinal surgery
• Current Recommendations for Surveillance and Surgery of Intraductal Papillary Mucinous Neoplasms May Overlook Some Patients with Cancer  
  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR, J Gastrointest Surg, 1/1/2015
• Simultaneous Knock-down of Bcl-xL and Mcl-1 Induces Apoptosis through Bax Activation in Pancreatic Cancer Cells  
  Takahashi H, Chen MC, Pham H, Matsuo Y, Ishiguro H, Reber HA, Takeyama H, Hines OJ, Eibl G., Biochim Biophys Acta, 1/1/2013
• miR-143 Decreases COX-2 mRNA Stability and Expression in Pancreatic Cancer Cells  
  Pham H, Ekaterina Rodriguez C, Donald GW, Hertzer KM, Jung XS, Chang HH, Moro A, Reber HA, Hines OJ, Eibl G, Biochem Biophys Res Commun, 1/1/2013
• High-fat, High-calorie Diet Promotes Early Pancreatic Neoplasia in the Conditional KrasG12D Mouse Model  
  Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G, Cancer Prev Res, 1/1/2013
• Impact of Tumor Grade on Pancreatic Cancer Prognosis: Validation of a Novel TNMG Staging System  
  Rochefort MM, Ankeny JS, Kadera BE, Donald GW, Isacoff W, Wainberg ZA, Hines OJ, Donahue TR, Reber HA, Tomlinson JS, Ann Surg Oncol, 1/1/2013
• Nonfunctional Pancreatic Neuroendocrine Tumors <2cm on Preoperative Imaging Are Associated with a Low Incidence of Nodal Metastasis and an Excellent Overall Survival  
  Toste PA, Kadera BE, Tatishchev SF, Dawson DW, Clerkin BM, Muthusamy R, Watson R, Tomlinson JS, Hines OJ, Reber HA, Donahue TR, J Gastrointest Surg, 1/1/2013
• The Effect of a Dedicated Endocrine Surgery Program on General Surgery Training: A Single Institutional Experience  
  Wiseman JE, Ituarte PH, Ro K, Pasternak JD, Quach CA, Tillou AK, Hines OJ, Hiatt JR, Yeh MW, Am J Surg., 1/1/2012
• Evidence for Activation of Mutated P53 by Apigenin in Human Pancreatic Cancer  
  King J, Lu GY, Li G, Moro A, Hiroki T, Chen M, Go VLW, Reber HA, Eibl G, Hines OJ, BBA - Molecular Cell Research, 1/1/2012
• The Evolving Management of Infected Pancreatic Necrosis  
  Donald GW, Donahue T, Reber HA, Hines OJ, American Surgeon, 1/1/2012
• Overexpression of CXCL5 Is Associated with Poor Survival of Patients with Pancreatic Cancer  
  Li A, King J, Moro J, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, Strieter RM, Burdick M, Go VLW, Reber HA, Eibl G, Hines OJ, American Journal of Pathology, 1/1/2011
• Morbidity and Mortality as a Televideoconference: A Randomized Prospective Evaluation of Learning and Perceptions  
  Lewis CE, Relan A, Hines OJ, Tillou A, Hiatt JR, Journal of the American College of Surgeons, 1/1/2011
• CXCR2-dependent Endothelial Progenitor Cell Mobilization in Pancreatic Cancer Growth  
  Li A, Cheng XJ, Moro A, Singh RK, Hines OJ, Eibl G, Translational Oncology, 1/1/2011
• Anti-Angiogenic Agents in Pancreatic Cancer: A Review  
  Assifi MM, Hines OJ, Anticancer Agents in Medical Chemistry, 1/1/2011
• Downstaging Chemotherapy and Alteration in the Classic Computed Tomography/magnetic Resonance Imaging Signs of Vascular Involvement in Patients with Pancreaticobiliary...  
  Donahue TR, Isacoff WH, Hines OJ, Tomlinson JS, Farrell JJ, Bhat YM, Garon E, Clerkin B, Reber HA, Archives of Surgery, 1/1/2011
• Appendicitis Equals Diverticulitis: A Challenge to Traditional Dogma  
  Assifi MM, Hines OJ, Archives of Surgery, 1/1/2011
• Web-based Portfolio: A Powerful New Instrument for Residents and Education Administrators  
  Lewis CE, Tillou A, Yeh MW, Quach C, Hiatt JR, Hines OJ, Journal of Surgical Research, 1/1/2010
• Evidence for Proteotoxicity in Beta-cells in Type 2 Diabetes, Toxic Islet Amyloid Polypeptide Oligomers Form Intracellularly in the Secretory Pathway  
  Gurlo T, Ryazantsev S, Huang C, Yeh M, Reber H, Hines OJ, O'Brien T, Glabe C, Butler P, American Journal of Pathology, 1/1/2010
• Cellular Histone Modification Patterns Predict Prognosis and Response to 5-fluorouracil Adjuvant Therapy in Resectable Pancreatic Adenocarcinoma  
  Manuyakorn A, Paulus R, Farrell J, Dawson NA, Tze S, Hines OJ, Reber H, Seligson DB, Horvath S, Kurdistani SK, Guha C, Dawson DW, Journal of Clinical Oncology, 1/1/2010
• The ZIP4 Pathway in Pancreatic Cancer  
  Donahue T, Hines OJ, Cancer Biology and Therapy, 1/1/2010
• Impact of Splenectomy on Thrombocytopenia, Chemotherapy, and Survival in Patients with Unresectable Pancreatic Cancer  
  Donahue TR, Kazanjian KK, Isacoff WH, Reber HA, Hines OJ, Journal of Gastrointestinal Surgery, 1/1/2010
• Quercetin Aglycone Is Bioavailable in Murine Pancreas and Pancreatic Xenografts  
  Zhang L, Angst E, Park JL, Moro A, Dawson DW, Reber HA, Eibl G, Hines OJ, Go VL, Lu QY, Journal of Agricultural Food Chemistry, 1/1/2010
• Epigenetic Regulation of N-myc Gene-1 in Pancreatic Cancer Cells  
  Angst E, Dawson DW, Nguyen A, Park JL, Reber HA, Hines OJ, Eibl G, Pancreas, 1/1/2010
• Howard A Reber, MD, Distinguished Professor of Surgery, UCLA School of Medicine  
  Hines OJ, Langenbecks Arch Surgery, 1/1/2010
• Bioluminescence Imaging of Angiogenesis in a Murine Orthotopic Pancreatic Cancer Model  
  Angst E, Chen M, Mojadidi M, Hines OJ, Reber HA, Eibl G, Molecular Imaging and Biology, 1/1/2010
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Books/Book Chapters

• Operative Techniques in Surgery 
  Chapter: Laparoscopic Pancreatic Debridement 
  Page 875.0 - 880.0Hines OJ, Hertzer KEditors: Operative Techniques in Surgery.Wolters Kluwer Health, Philadelphia, PAEdition Firs,2014
• Current Surgical Therapy 
  Chapter: Pancreatic Ductal Disruptions Leading to Pancreatic Fistula, Pancreatic Ascites, or Pancreatic Pleural Effusion 
  Hines OJ, Graham DEditors: Cameron J, Cameron A.Mosby/Elsevier, Philadelphia, PAEdition Elev,2013
• Essentials of General Surgery 
  Chapter: Biliary Tract 
  Hines OJ, Cason FD, Edwards M, Hopkins MAEditors: Lawrence P.Wolters Kluwer, Baltimore, MDEdition 5th,2013
• Shackelford's Surgery of the Alimentary Tract 
  Chapter: Anatomy and Physiology of the Stomach 
  King J, Hines OJEditors: Yeo, CJ.Mosby/Elsevier, Philadelphia, PAEdition 7th,2013
• Gut Instincts - a Clinician's Handbood of Digestive and Liver Disease 
  Chapter: Ileus and Bowel Obstruction 
  Page 193.0 - 198.0Morris LF, Hines OJEditors: Esralian E.Slack, Thorofare, NJ2012
• Current Surgical Therapy 
  Chapter: Palliative Therapy for Pancreatic Cancer 
  Page 434.0 - 440.0King J, Hines OJEditors: Cameron J, Cameron A.Mosby/Elsevier, Philadelphia, PAEdition 10th,2011
• Up to Date 
  Chapter: Distal Pancreatectomy 
  Donahue TR, Hines OJWaltham, MA2009
• Current Surgical Therapy 
  Chapter: Periampullary Cancer 
  Hines OJ, Reber HAEditors: Cameron J.Mosby/Elsevier, Philadelphia, PA2008
• Diseases of the Pancreas: Current Surgical Therapy 
  Chapter: Indications for Resection of Pancreatic Cancer 
  Page 559.0 - 565.0Hines OJ, Reber HAEditors: Cameron J, Beger H.Springer-Verlag, Heidelberg, Germany2008
• Maingot's Abdominal Operations 
  Chapter: Chronic Pancreatitis 
  Page 983.0 - 997.0Hines OJ, Reber HAEditors: Zinner, MJ, Ashley SW.Appleton & Lange, Stamford, CTEdition Tent,2007
• Advanced Therapy in Gastroenterology and Liver Disease 
  Chapter: Chronic Pancreatitis: Surgical Considerations 
  Page 784.0 - 788.0Hines OJ, Reber HAEditors: Bayless, TM, Diehl, AM.BC Decker Inc.2005
• Clinical Pancreatology 
  Chapter: Indications for Surgery in Acute Pancreatitis 
  Page 125.0 - 132.0Hines OJ, Reber HAEditors: Munoz, JE.Blackwell Publishing2005
• The Handbook of Plastic Surgery 
  Chapter: Primary Treatment of Breast Cancer 
  Page 867.0 - 874.0Beanes, S, Hines, OJU. INFRMA-HC2004
• Procedures and Techniques in Endrocrinologic Surgery 
  Chapter: Cushing's Syndromes, Adrenocortical Carcinoma, and Estrogen and Androgen Secreting Tumors 
  Page 381.0 - 400.0Wente M, Eibl G, Hines OJEditors: Schwartz A, Pertsemlidis D, Gagner M.Marcel Dekker, Inc2004
• The Practice of General Surgery 
  Chapter: Acute Pancreatitis 
  Page 738.0 - 742.0Sarr MG, Hines, OJ, Reber, HAEditors: Bland K.W.B. Saunders2002
• Shackelford's Surgery of the Alimentary Tract 
  Chapter: Anatomy and Embryology of the Pancreas 
  Page 3.0 - 8.0Reemtsen B, Hines, OJ, Reber, HAEditors: Zuidema, GD, Yeo, CJ.W.B. SaundersEdition Fift,2001
• Complications in Urologic Surgery 
  Chapter: Management of Bowel Complications 
  Page 177.0 - 185.0Hines, OJW.B. Saunders, Philadelphia, PAEdition 3.0,2001
• Oxford Textbook of Surgery 
  Chapter: Acute Pancreatitis 
  Page 1765. - 1778.Hines, OJ, Reber, HAEditors: Morris, PJ, Wood, WC.Oxford University Press, OxfordEdition Seco,2000
• Maingot's Abdominal Operations 
  Chapter: Lesions of the Mesentery, Omentum and Retroperitoneum 
  Page 709.0 - 721.0Hines, OJ, Ashley, SWEditors: Zinner, MJ.Appleton & Lange, Stamford, CTEdition Tent,1997
• Essentials of Experimental Surgery - Gastroenterology 
  Chapter: Absorption Studies of the Gastrointestinal Tract 
  Page 1.0 - 11.0Hines, OJ, Ashley, SW, McFadden, DWEditors: Jensen, SL, Gregersen, H, Moody, FG, Shokouh-Amiri, H.Harwood Academic Publishers, New York, Chur, Switzerland1996
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Abstracts/Posters

• 2014 Society of University Surgeons Presidential Address
  Hines OJ, Surgery, 1/1/2014
• Diet-Induced Obesity Results in Robust Differential Inflammation of Peripancreatic and Visceral Adipose Tissue Depots in the KrasG12D Mouse Model of Pancreatic Cancer
  Hertzer KM, Moro A, Hines OJ, Eibl G, Pancreas, 1/1/2014
• Long-Term Survival in Patients With Pancreatic Ductal Adenocarcinoma
  Stark A, Rochefort M, Sacks G, Hertzer K, Ankeny J, Donahue T, Reber H, Tomlinson J, Eibl G, Hines O, Pancreas, 1/1/2014
• The Surgical Forum
  Hines OJ, Introduction in the Supplement to the Journal of the American College of Surgeons, 1/1/2013
• Impact of Tumor Grade on Prognosis in Pancreatic Cancer: Validation of a Novel "TNMG" Staging System.
  Rochefort MM, Donald GW, Kadera BE, Donahue TR, Reber HA, Hines OJ, Tomlinson JS, Journal of Surgical Research, 1/1/2013
• Prophylactic Antibiotics for Surgical Site Infection in Pancreaticoduodenectomy: Does the SCIP-approved Regimen Provide Adequate Coverage?
  Donald GW, Chen F, Clerkin B, Tomlinson JS, Donahue TR, Reber HA, Hines OJ, Journal of Surgical Research, 1/1/2013
• The Bioflavonoid Baicalein Inhibits Human Pancreatic Cancer Cell Migration
  Donald GW, Chen M, Moro A, Pham H, Hertzer KM, Reber HA, Hines OJ, Eibl G., Journal of Surgical Research, 1/1/2013
• A High Fat, High Calorie Diet Leads to Inflammation of the Pancreas and Adipose Tissue in the KrasG12D Mouse Model
  Hertzer KM, Moro A, Dawson DW, Hines OJ, Eibl G, Pancreas, 1/1/2013
• Simultaneous Knock-down of Bcl-xL and Mcl-1 Induces Apoptosis in Gemcitabine-sensitive and -resistant Pancreatic Cancer Cells
  Takahashi H, Brovman EY, Matsuo Y, Ishiguro H, Chen M, Pham H, Reber HA, Takeyama H, Eibl G, Hines OJ, Journal of Surgical Research, 1/1/2012
• Enhanced Growth of Syngeneic Pancreatic Cancer in CXCR2 Deficient Mice
  Donald GW, Assifi M, Moro A, Chen M, Eibl G, Reber HA, Dawson D, Li VG, Hines OJ, Journal of Surgical Research, 1/1/2012
• Severe Upper Gastrointestinal Hemorrhage from Linear Gastric Ulcers in Large Hiatal Hernias: A Large Prospective Case Series of Cameron Ulcers
  Camus M, Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Machicado GA, Dulai CS, Hines OJ, Endoscopy, 1/1/2012
• Baicalein Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine through Modulation of MCL-1 Expression
  Brovman EY, Takahashi, Chen M, Go VL, Reber HA, Eibl G, Hines OJ, Journal of Surgical Research, 1/1/2011
• CXCL5-Mediated Signaling Events and in Vitro Angiogenesis in Human Pancreatic Cancer
  King JC, Li A, Reber HA, Eibl G, Hines OJ, Journal of Surgical Research, 1/1/2011
• Neoadjuvant Therapy in Pancreatic Adenocarcinoma: A Meta-analysis of Phase II Trials
  Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ, Journal of Surgical Research, 1/1/2011
• Eicosapentaenoic Acid Decreases Fatty Acid Synthase through an AKT Dependent Pathway in Pancreatic Cancer Cells
  Chen MC, Esquivel S, Reber HA, Hines OJ, Go VLW, Eibl G, Pancreas, 1/1/2011
• COX-2 Depending CXC-chemokines Production in Human Pancreatic Cancer Cells
  Satake M, Eibl G, Kuroda N, Hirano T, Ishikawa H, Nishii M, Babaya A, Go VL, Reber H, Fukuda Y, Hines OJ, Fujimoto J., Pancreas, 1/1/2011
• Anti-apptotic Bcl-2 Family Protein Mcl-1 Plays a Critical Role in Baicalein-induced Apoptosis in Human Pancreatic Cancer Cells
  Takahashi H, Chen MC, Harris DM, Pham H, Reber HA, Hines OJ, Go VLW, Eibl G, Gastroenterology, 1/1/2011
• Vitamin D3 Regulates 15-hydroxyprostaglandin Dehydrogenase in Human Pancreatic Cancer Cells
  Pham H, Chen MC, Takahashi H, Reber HA, Hines OJ, Eibl G, Gastroenterology, 1/1/2011
• Eicosapentaenoic Acid Induces Apoptosis through an Akt-dependent Pathway in Pancreatic Cancer Cells
  Chen MC, Park JL, Srihari P, Reber HA, Hines OJ, Go VLW, Eibl G, Pancreas, 1/1/2011
• Eicosapentaenoic Acid Decreases Fatty Acid Synthase Through an Akt-Dependent Pathway in Pancreatic Cancer Cells
  Chen MC, Esquivel S, Reber HA, Hines OJ, Go VLW, Eibl G, Pancreas, 1/1/2011
• Book Review: Schwartz's Principles of Surgery. 9th Edition
  Hines OJ, Annals of Surgery, 1/1/2010
• Apigenin Induces Pancreatic Cancer Cell Apoptosis by a P53-mediated Mechanism
  King JC, Li A, Reber HA, Go VW, Eibl G, Hines OJ, Journal of Surgical Research, 1/1/2010
• Baicalein Inhibits Pancreatic Cancer Cell Growth and Induces Apoptosis by Reducing PGE2 Synthesis
  Chen MC, Takahashi H, Pham H, Harris CM, Angst E, Reber HA, Hines OJ, Go VLW, Eibl G, Gastroenterology, 1/1/2010
• Apigenin Inhibits NNK-Induced FAK Y397 Activation in Pancreatic Cells.
  Pham H, Chen MC, King JC, Takahashi H, Pandol SJ, Reber HA, Hines OJ, Eibl G, Gastroenterology, 1/1/2010
• Morbidity and Mortality as a Televideoconference: A Randomonized Prospective Evaluation of Learning and Perceptions
  Lewis CE, Relan A, Hines OJ, Tillou A, Hiatt JR, Journal of the American College of Surgeons, 1/1/2010
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Lectures

• Impact of Tumor Grade on Prognosis in Pancreatic Cancer: Validation of a Novel "TNMG" Staging System 
  New Orleans, LA - 1/5./2013
• Distal Pancreatectomy: Incidence of Postoperative Diabetes 
  1/1/2007
• CXC Chemokines Are Elevated in the Serum and Tumors of Pancreatic Cancer Patients 
  San Diego, CA - 1/1/2007
• Risk of Malignancy in Resected Cystic Tumors of the Pancreas <3 Cm in Size: Is It Safe to Observe Asymptomatic Patients? A Multi-institutional Study 
  Washington, DC - 1/1/2007
• Defining N2 Disease in Resected Adenocarcinoma of the Pancreas 
  Washington, DC - 1/1/2007
• RNA-mediated Gene Silencing of VEGF-C Inhibits the Growth of Human Pancreatic Cancer 
  1/1/2006
• Laparoscopic Distal Pancreatectomy: A Cases Series 
  1/1/2006
• Opposing Actions of Prostaglandin E2 on Pancreatic Cancer Cell Proliferation and Invasion 
  1/1/2006
• Comprehensive Analysis of Prostaglandin E2 Production in Pancreatic Cancer Cells 
  1/1/2006
• Resection of Pancreatic Neuroendocrine Tumors: Results of 70 Cases. 
  1/1/2006
• Ampullary Carcinoma: How Population-based Outcomes Compare to Academic Reports 
  1/1/2006
• Broad Spectrum G Protein-coupled Receptor Antagonist [DArg1,DTrp5,7,9,Leu11]SP: A Dual Inhibitor of Growth and Chemokine Mediated Angiogenesis in Pancreatic Cancer 
  1/1/2005
• GDNF Stimulates Invasion of Pancreatic Cancer Cells by Activation of the Ret Receptor and MAPK Signaling 
  1/1/2005
• Improved Survival for Adenocarcinoma of the Pancreas after Pancreaticoduodenectomy 
  1/1/2005
• Management of Pancreatic Fistulas after Pancreaticoduodenectomy: Results in 437 Consecutive Patients 
  1/1/2005
• Activation of Nuclear Receptor PPAR-gamma Inhibits Invasion in Pancreatic Cancer Cells through Modulation of the Plasminogen Activator Sytem 
  1/1/2004
• Broad-spectrum G Protein-coupled Receptor Antagonist [Darg1, Dtrp5,7,9, Lue11]AP: A Novel Potent Inhibitor of Growth and Angiogenesis in Pancreatic Cancer 
  1/1/2004
• Suramin Inhibits Not Only Tumor Growth and Metastasis but Angiogenesis in Experimental Human Pancreatic Cancer 
  1/1/2004
• Matriptase Is Anew Hpoxia Inducible Regulator of Tumor Cell Invasion and Metastasis 
  1/1/2004
• Distinct Expression of CXC Chemokines in Human Pancreatic Cancer Tissues 
  1/1/2004
• Morbidity after Pancreaticoduodenectomy: Analysis of 350 Consecutive Cases 
  1/1/2003
• Comparison of Different Antiangiogenic Treatment Strategies for Experimental Human Pancreatic Cancer 
  1/1/2003
• Selective Endothelin-A-receptor Blockade Reduces the Growth of Receptor-positive Pancreatic Cancer in Vitro and in Vivo 
  1/1/2003
• 15-deoxy-prostaglandin J2 Stimulates Cathepsin-L Expression in Human Pancreatic Cancer Cells through Multiple Pathways 
  1/1/2003
• Inhibition of Hypoxia Inducible Factor-1 Reduces Neoangiogenesis and VEGF Production in Pancreatic Cancer in Vivo and in Vitro 
  1/1/2003
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Other

• Distal pancreatectomy: Techniques 
  Hines OJ, Donahue TR
  http://www.uptodate.com/contents/distal-pancreatectomy-techniques
  UpToDate, Wolters Kluwer Health - 2012-08-15