OmarYusufMianMDPhD

PubMed

• 142 citations
  NCCN Guidelines® Insights: Bladder Cancer, Version 2.2022.
  Thomas W Flaig, Philippe E Spiess, Michael Abern, Neeraj Agarwal, Rick Bangs
  Journal of the National Comprehensive Cancer Network. 2022-08-01
• 8 citations
  Lineage plasticity and treatment resistance in prostate cancer: the intersection of genetics, epigenetics, and evolution.
  Jarrell Imamura, Shinjini Ganguly, Andrew Muskara, Ross S Liao, Jane K Nguyen
  Frontiers in Endocrinology. 2023-01-01
• 65 citations
  Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
  Robert Vander Velde, Nara Yoon, Viktoriya Marusyk, Arda Durmaz, Andrew Dhawan
  Nature Communications. 2020-05-14

Journal Articles

• Use of 5-alpha-reductase inhibitors as alternatives to luteinizinghormone releasing hormone (LHRH) analogs or anti-androgens for prostate downsizing before brachytherapy  
  Bae HJ, Mian Omar Y, Vaidya D, DeWeese TL, Song DY, Pract Radiat Oncol, 1/10/2017
• Current controversies in prostate brachytherapy for prostate cancer  
  Ibrahim Abu-Gheida, Christopher Fleming, Paul Ramia, Omar Mian, Rahul Tendulkar and Jay Ciezki, MD, Applied Radiation Oncology, 1/1/2017
• The evolving role of molecular profiling in prostate cancer: basal and luminal subtyping transcends tissue of origin  
  Mian OY, Tendulkar RD, Abazeed ME., Transl Cancer Res, 1/1/2017
• An imageguidance system for dynamic dose calculation in prostate brachytherapy using ultrasound and fluoroscopy  
  Kuo N, Dehghan E, Deguet A, Omar Y. Mian., Le Y, Burdette EC, Fichtinger G, Prince JL, Song DY, Lee J., Med Phys, 1/1/2014
• The human sodium-dependent ascorbic acid transporters SLC23A1 and SLC23A2 do not mediate ascorbic acid release in the proximal renal epithelial cell  
  Eck P, Kwon O, Chen S, Omar Y. Mian, Levine M, Physiol Rep, 1/1/2013
• Methyl-binding domain protein 2-dependent proliferation and survival of breast cancer cells  
  Omar Y. Mian, Shou Zhen Wang, Sheng Zu Zhu, Merlin Gnanapragasam, Laura Graham, Harry Bear, Gordon D. Ginder, Mol. Cancer Res, 1/1/2011
• Atherosclerotic Plaque Macrophage Transcriptional Regulators Are Expressed in Blood and Modulated by Tristetraprolin  
  Willmar D. Patino, Ju-Gyeong Kang, Satoaki Matoba, Omar Y. Mian, Bernadette R. Gochuico, and Paul M. Hwang, Circ. Res, 1/1/2006
• Circulating transcriptome reveals markers of atherosclerosis  
  Willmar D. Patino, Omar Y. Mian, Ju-Gyeong Kang, Satoaki Matoba, Linda D. Bartlett, Brenda Holbrook, Hugh H. Trout III, Louis Kozloff, and Paul M. Hwang, PNAS, 1/1/2005
• Current and Future Applications of SAGE to Cardiovascular Medicine  
  Patino W.D., Omar Y. Mian, Shizukuda Y., Hwang P.M, Trends Cardiovasc. Med., 1/1/2003
• Serial Analysis of Gene Expression: Technical Considerations and Applications to Cardiovascular Biology  
  Patino W., Omar Y. Mian, Hwang P., Circ. Res, 1/1/2002
• Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in mice  
  Shizukuda Y, Matoba S, Omar Y. Mian, Nguyen T, Hwang PM, Mol. Cell Biochem
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Books/Book Chapters

• Pocket Guide to Radiation Oncology 
  Chapter: Chapter 14: Occult Primary Cancer of the Head and Neck 
  Omar Y. Mian and Ana KiessDemos Medical Publishing2017
• Essentials of Clinical Radiation Oncology 
  Chapter: Chapter 41: Penile Cancer 
  Rupesh Kotecha, Omar Y. Mian, Rahul D. TendulkarDemos Medical Publishing2017
• Advances in Developmental Biology 
  Chapter: The Role of the Epigenetic Signal, DNA Methylation, in Gene Regulation During Erythroid Development, Red Cell Development 
  Gordon D. Ginder, Merlin Gnanapragasam, Omar Y. MianElsevier2008

Abstracts/Posters

• Genetic and Epigenetic Profiling of Small Cell Bladder Cancer (SCBC).
  Petros Grivas, Vadim S. Koshkin, Jordan Reynolds, Paul Elson, Cristina Magi-Galluzzi, Jesse McKenney, Karen Streator Smith, Bonnie Shadrach, Kumiko Isse, Laura R. Saun..., ASTRO Annual Meeting, 1/1/2017
• Molecular Profiling of Small Cell Bladder Cancer (SCBC) Reveals Gene Expression Determinants of an Aggressive Phenotype
  Vadim S. Koshkin, Jordan Reynolds, Paul Elson, Cristina Magi-Galluzzi, Jesse McKenney, Karen Streator Smith, Bonnie Shadrach, Kumiko Isse, Laura R. Saunders, Ming Hu, ..., ASCO Annual Meeting, 1/1/2017
• DNA Methylation and H3K27M Mutant Allele Frequency as a biomarker of therapeutic response in DIPG
  Adam DeLong, Peter Anderson, Stephen Dombrowski, Erin Murphy, and Omar Mian, Lepow Day Research Presentation, CWRU SOM, 1/1/2017
• Prostate Volume Reduction Prior to Brachytherapy Using 5-alpha Reductase Inhibition Alone without Androgen Blockade
  HJ Bae, O Mian, Y Le, T DeWeese, D Song, Brachytherapy, American Brachytherapy Society Annual Meeting, 1/1/2016
• Partial Agonist Activity of Hydroxyflutamide Induces AR-and TOP2B-dependent DNA Double Strand Breaks and Radiosensitizes Prostate Cancer Cells
  JB Coulter, MC Haffner, OY Mian, K Kim, M Hedayati, Y Zhang, H Zhou, ... TL DeWeese, International journal of radiation oncology, biology, physics, American Society of Therapeutic Radiation Oncology Annual Meeting, 1/1/2016
• Volumetric Assessment of Tumor Vessel Interaction Is a Predictor of Surgical Candidacy in Patients With Borderline Resectable and Locally Advanced Pancreatic Cancer Tr...
  Z Cheng, LM Rosati, L Chen, OY Mian, A Narang, Y Cao, J Moore, ... T McNutt, International journal of radiation oncology, biology, physics, American Society of Therapeutic Radiation Oncology Annual Meeting, 1/1/2016
• Preference to Spare Critical Anatomy Near Gross Tumor Volume Is Associated With Poor Pathologic Complete Response With Breath HoldBased Neoadjuvant Stereotactic Body R...
  Z Cheng, LM Rosati, L Chen, SP Robertson, J Moore, LC Peng, OY Mian, ... JM Herman, T McNutt, International journal of radiation oncology, biology, physics, American Society of Therapeutic Radiation Oncology Annual Meeting, 1/1/2016
• SU-FR-47: Quantitative Shape Relationship Analysis of PTV Modification for Critical Anatomy Sparing and Its Impact On Pathologic Response for Neoadjuvant Stereotactic ...
  Z Cheng, L Rosati, L Chen, S Robertson, J Moore, L Peng, O Mian, ... T McNutt, Medical Physics, AAPM Annual Meeting, 1/1/2016
• Reductions in Prostatic and Urethral Doses Are Associated With Less Acute Morbidity in Patients Undergoing Pd-103 Brachytherapy: Substantiation of the Rationale for Fo...
  A Ferro, H Bae, SP Robertson, Y Le, TR McNutt, OY Mian, C Gergis, et al, and DY Song, International journal of radiation oncology, biology, physics, American Society of Therapeutic Radiation Oncology Annual Meeting, 1/1/2016
• Neoadjuvant Stereotactic Body Radiation Therapy Dosimetric Parameters Predict for Pathologic Outcomes and Survival in Pancreas Adenocarcinoma
  L Chen, Y Cao, A Narang, Z Cheng, LM Rosati, OY Mian, SP Robertson, et al, and JM Herman, International journal of radiation oncology, biology, physics, American Society of Therapeutic Radiation Oncology Annual Meeting, 1/1/2016
• Pancreas Stereotactic Body Radiation Therapy Demonstrates Minimal Acute Treatment-Related Toxicity.
  Y Cao, L Chen, ZD Guss, J Moore, OY Mian, CC Hsu, SP Robertson, ...JM Herman, International journal of radiation oncology, biology, physics, American Society of Therapeutic Radiation Oncology Annual Meeting, 1/1/2016
• A Prospective Study of 80 patients Evaluating Registered Ultrasound and Fluoroscopy (RUF) For Intraoperative Dose Calculation: Improved Accuracy Compared To Convention...
  Omar Y. Mian, Carol Gergis, Adam Ferro, Yi Le, Scott Robertson, Robert Hobbs, Jerry L. Prince, Todd McNutt, Theodore L. DeWeese, Junghoon Lee, Daniel Y. Song, American Society of Therapeutic Radiation Oncology Annual Meeting., 1/1/2016
• A retrospective review of 366 patients treated with LDR prostate brachytherapy at a single institution: histopathologic, biochemical, and dosimetric predictors of outc...
  Omar Y. Mian, MD, PhD, Scott Robertson PhD, Amol Narang MD, Hee Joon Bae BS, Phuoc Tran MD, PhD, Theodore L. DeWeese MD, Danny Y. Song, MD, American Brachytherapy Society Annual Meeting, Orlando, FL, 1/1/2015
• Dosimetric predictors of sexual function decline following LDR brachytherapy for prostate cancer (PCa)
  Omar Y. Mian, Scott Robertson, Amol Narang, Sameer Agarwal, Hee Joon Bae, Todd McNutt, Phuoc Tran, Theodore L. DeWeese, Danny Y. Song, ASCO/Genitourinary Meeting, San Francisco, CA, 1/1/2015
• Total Lesion Glycolysis as a Predictor of Pathologic Outcomes Locally Advanced and Borderline Resectable Patients Undergoing Surgery after Preoperative Stereotactic Bo...
  Omar Y. Mian, Linda Chen, Amol Narang, Jeffrey Leal, Steven Rowe, Avani Dholakia, Shalini Moningi, Lauren Rosati, Joseph Herman., American Society of Therapeutic Radiation Oncology Annual Meeting, San Antonio, TX, 1/1/2015
• A Novel Technology for Noninvasive Detection of Prostate Cancer (PCa) DNA in the Blood and Urine of Men With High Risk Pca Receiving Radiation Therapy and Androgen Sup...
  Omar Y. Mian, Michael Haffner, Jonathan Coulter, David Esopi, Jennifer Meyers, Carol Gergis, Ryan Assadi, William Nelson, Srinivasan Yegnasubramanian, Theodore DeWeese, American Society of Therapeutic Radiation Oncology Annual Meeting, San Antonio, TX, 1/1/2015
• Reduced lymphocytopenia following stereotactic body radiation therapy (SBRT) for spine metastases compared with conventional radiation therapy (CRT).
  Omar Y. Mian, Uri Hadelsberg, Kubra Gokce, Sara Alcorn, Susannah Ellsworth, Michael Lim, Jean Paul Wolinsky, Chetan Bettegowda, Daniel Sciubba, Ziya Gokaslan, Stuart G..., American Society of Therapeutic Radiation Oncology Annual Meeting, San Francisco, CA, 1/1/2014
• Timely Radiosurgery for Spine Metastases per RTOG 0613 Guidelines using a Rapidly Deployable Automated Planning Script (FastPlan)
  Omar Y. Mian, O. Thomas, Y. Le, T. McNutt, M. Lim, D. Rigamonti, K. Redmond, L. Kleinberg, American Society of Therapeutic Radiation Oncology Annual Meeting, Atlanta, GA, 1/1/2013
• Methyl Binding Domain Protein 2 (MBD2) Promotes Epithelial Dedifferentiation in Breast Cancer.
  Omar Y. Mian and Gordon D. Ginder, American Association for Cancer Research, Joint National Meeting, Washington, DC, 1/1/2010
• Methyl Binding Domain Proteins Maintain Epithelial Dedifferentiation and Therapeutic Resistance in Breast Cancer
  Omar Y. Mian, Shou Zhen Wang, Sheng Zu Zhu, Merlin N. Gnanapragasam, Gordon D. Ginder, American College of Physicians, Virginia Chapter Meeting, McLean, VA, 1/1/2009
• MBD2 Mediates Epigenetic Silencing Of Maspin In MCF-7 Cells And Contributes To Elevated Tumor Grade In 3D Culture
  Omar Y. Mian, Shou Zhen Wang, Sheng Zu Zhu, Merlin N. Gnanapragasam, Gordon D. Ginder, Keystone Symposia on Epigenetics in Health and Disease, Keystone, CO, 1/1/2009
• MBD2 inhibits migration, differentiation, and tumor suppressor expression in the breast cancer cell line, MCF7.
  Omar Y. Mian, Shou Zhen Wang, Sheng Zu Zhu, Merlin N. Gnanapragasam, Gordon D. Ginder, American Society for Clinical investigation/Association of American Physicians (ASCI/AAP) Joint Meeting, Chicago, IL, 1/1/2008
• Methyl Binding Domain Protein 2 (MBD2) Mediates Epigenetic Silencing of Maspin in MCF7 Cells and Contributes to Elevated Tumor Grade in 3D Culture.
  Omar Y. Mian, Shou Zhen Wang, Sheng Zu Zhu, Merlin N. Gnanapragasam, Gordon D. Ginder, ICAMS Retreat, Molecular Biology and Genetics, Richmond, VA, 1/1/2008
• Inter-individual Gene Expression Variation Assessed by SAGE in Human Monocytes.
  Omar Y. Mian, Willmar D. Patino, Andrew Wragg, Satoaki Matoba, Ju-Gyeong Kang, Paul M. Hwang, Keystone Symposia: The Cellular Biology of Atherosclerosis., Keystone CO, 1/1/2005
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Lectures

• Circulating tumor DNA (ctDNA) as a precision tool in radiotherapy. 
  Washington, DC - 1/4/2017
• Controversies in the contemporary management of prostate cancer: Emerging role of biomarkers 
  Sheraton Hotel, Cordoba, Argentina - 1/2/2017
• Dosimetric Predictors of Sexual Function Decline Following LDR Brachytherapy for Prostate Cancer (PCa) 
  San Antonio, TX - 1/1/2015
• Non-invasive Detection of Prostate Cancer-Specific DNA in Blood and Urine 
  James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, MD - 1/1/2014
• A Prospective Study of Registered Ultrasound and Fluoroscopy (RUF) for Intraoperative Dose Calculation: Improved Accuracy Compared To Current Ultrasound-based Intraope... 
  San Diego, CA - 1/1/2014
• Methyl Binding Domain Proteins Maintain Epithelial Dedifferentiation and Therapeutic Resistance in Breast Cancer 
  Richmond, VA - 1/1/2009
• Methyl Binding Domain Proteins Maintain Epithelial Dedifferentiation and Therapeutic Resistance in Breast Cancer. 
  Charlottesville, VA - 1/1/2009
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Other

• Integrated Molecular Profiling of GU Tumors: Applications for Personalized Therapy 
  Nature Webinar
  Nature.com
  1/28/2017
• Thesis, The Role of the Methyl DNA Binding Domain Protein 2 (MBD2) in Breast Cancer