NirmishShahMD

Medicine/Pediatrics • Durham, NC

Associate Professor at Duke University

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Office
40 Medicine Circle
Durham, NC 27710
Phone+1 919-684-8111

Education & Training

Duke University HospitalFellowship, Pediatric Hematology/Oncology, 2010
ECU Health Medical Center/East Carolina UniversityResidency, Internal Medicine/Pediatrics, 2000 - 2004
American University of the Caribbean School of MedicineClass of 2000

Certifications & Licensure

NC State Medical License 2000 - 2025

Clinical Trials

Evaluation of the Duration of Therapy for Thrombosis in Children Start of enrollment: 2008 Mar 01
Completed
Phase 3
Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo Start of enrollment: 2011 May 01
Completed
Phase 2
A Phase II Trial of Regadenoson in Sickle Cell Anemia Start of enrollment: 2013 Jul 01
Completed
Phase 2
Use of a Mobile-based App for SCD Patients Start of enrollment: 2012 Jun 01
Completed
Use of Mobile Technology for Intensive Training in Medication Management Start of enrollment: 2014 May 01
Completed
Not Applicable
Apixaban in Patients With Sickle Cell Disease Start of enrollment: 2015 Jan 01
Terminated
Phase 3
Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD) Start of enrollment: 2018 Feb 05
Terminated
Not Applicable
Ketamine Infusion for Sickle Cell Pain Crisis Start of enrollment: 2022 Jan 01
Withdrawn
Phase 4
Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications Start of enrollment: 2020 Aug 12
Completed
Not Applicable
Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease Start of enrollment: 2020 Oct 27
Completed
Not Applicable
A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises Start of enrollment: 2021 Oct 26
Active, not recruiting
Phase 3
Roles: Principal Investigator
Patient-Empowered Mobile Technology in Hospitalized Patients (TRU-PAIN) Start of enrollment: 2016 Aug 01
Completed
Not Applicable
Roles: Contact, Principal Investigator
Patient-Empowered Mobile Technology in Hospitalized Patients (TRU-PAIN) Start of enrollment: 2016 Aug 01
Completed
Not Applicable
Roles: Contact, Principal Investigator
Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain Start of enrollment: 2021 Nov 24
Recruiting
Phase 2
Roles: Contact
AB1 in Adult Patients With Sickle Cell Disease (SCD) Start of enrollment: 2022 Dec 05
Recruiting
Phase 1, Phase 2
Roles: Contact, Principal Investigator, Sponsor-Investigator
Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers Start of enrollment: 2018 Apr 06
Completed
Phase 2
Roles: Contact
Predictors of Pain in Sickle Cell Disease Start of enrollment: 2024 Apr 01
Not yet recruiting
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

23 citations
Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial.
James F. Casella, Bruce A. Barton, Julie Kanter, L. Vandy Black, Suvankar Majumdar
JAMA. 2021-04-20
18 citations
Perspectives of individuals with sickle cell disease on barriers to care.
Shannon Phillips, Yumei Chen, Rita Masese, Laurence Noisette, Kasey Jordan
Plos One. 2022-01-01
28 citations
Pregnancy outcomes with hydroxyurea use in women with sickle cell disease.
Barbara L Kroner, Jane S Hankins, Norma Pugh, Abdullah Kutlar, Allison A King
American Journal of Hematology. 2022-05-01

Journal Articles

Effects of Red Blood Cell (RBC) Transfusion on Sickle Cell Disease Recipient Plasma and RBC Metabolism
Nirmish Shah, Ian Welsby, Reed Kamyszek, Andrea Ansari, Transfusion
Transition to Adult Care in Sickle Cell Disease: A Longitudinal Study of Clinical Characteristics and Disease Severity
Nirmish Shah, Gary Maslow, Pediatric Blood & Cancer

Press Mentions

GBT Presents Positive New Data on Oxbryta® (Voxelotor) in Patients with Sickle Cell Disease at ASH Annual Meeting and ExpositionDecember 12th, 2021
Development of a Severity Classification System for Sickle Cell DiseaseOctober 28th, 2020
Treating Sickle Cell Disease with HSCTFebruary 19th, 2020
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