Nils W.G. Lambrecht MD

PubMed

• Long COVID has variable incidence and clinical presentations: our 6-country collaborative study.
  Sandor Szabo, Iryna Muzyka, Veronika Muller, Attila J Szabo, Attila Szijártó
  Inflammopharmacology. 2025-03-01
• 8 citations
  Single-cell dissection of Merkel cell carcinoma heterogeneity unveils transcriptomic plasticity and therapeutic vulnerabilities.
  Bhaba K Das, Aarthi Kannan, Graham J Velasco, Mikaela D Kunika, Nils Lambrecht
  Cell Reports. Medicine. 2023-07-18
• 1 citations
  IGF-1/IGFBP-3 Serum Ratio as a Robust Measure to Determine GH Deficiency and Guide Human Recombinant GH Therapy.
  Nils Lambrecht
  The Journal of Clinical Endocrinology and Metabolism. 2023-03-10

Journal Articles

• Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of non-alcoholic fatty liver disease  
  SH. Ganji, G.D. Kukes, N. Lambrecht, ML. Kashyap, VS. Kamanna, Am J Physiol Gastrointest Liver Physiol, 2/1/2014
• The ghrelin activating enzyme ghrelin-O-acyltransferase (GOAT) is present in human plasma and expressed dependent on body mass index  
  M. Goebel-Stengel, T. Hofmann, U. Elbelt, P. Teuffel, A. Ahnis, P. Kobelt, N. Lambrecht, B. Klapp, A. Stengel, Peptides, 1/1/2013
• Ghrelin and NUCB2/nesfatin-1 are expressed in the same gastric cell and differentially correlated with body mass index in obese subjects  
  A. Stengel, T. Hofmann, M. Goebel-Stengel, V. Lembke, A. Ahnis, U. Elbelt, N. Lambrecht, J. Ordemann, B.F. Klapp, P. Kobelt, Histochem Cell Biol, 1/1/2013
• Lung Cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention  
  MR. Jadus, J. Natividad, A. Mai1, Y. Ouyang, N. Lambrecht, S. Szabo, L. Ge, N. Hoa, and MG. Dacosta-Iyer, Clinical and Developmental Immunology, 1/1/2012
• Excessive therapeutic response in a case of blastic plasmacytoid dendritic cell neoplasm  
  M.P. Shieh, N. Reisian, V. Walavalkar, L.M. Slater, N. Lambrecht, Clin Adv Hematol Oncol, 1/1/2012
• Abdominal surgery inhibits circulating acyl ghrelin and ghrelin-O-acyltransferase levels in rats: role of the somatostatin receptor subtype 2  
  A. Stengel, M. Goebel-Stengel, L. Wang, A. Shaikh, N. Lambrecht, J. Rivier, Y. Tache, American Journal of Physiology - Gastrointestinal and Liver Physiology, 1/1/2011
• Lipopolysaccharide differentially decreases plasma acyl and desacyl ghrelin levels in rats: potential role of the circulating ghrelin acylating enzyme GOAT  
  A. Stengel, M. Goebel, L. Wang, J.R. Reeve Jr., Y. Tache, N. Lambrecht, Peptides, 1/1/2010
• Impaired Intestinal Vitamin B(1) (Thiamin) Uptake in Thiamin Transporter-2-Deficient Mice  
  J.C. Reidling, N. Lambrecht, M. Kassir, H.M. Said, Gastroenterology, 1/1/2010
• Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa  
  A. Stengel, M. Goebel, L. Wang, Y. Tache, G. Sachs, N. Lambrecht, Biochemical and Biophysical Research Communications, 1/1/2010
• Nesfatin-1 immunoreactivity in rat brain and spinal cord autonomic nuclei  
  M. Goebel, A. Stengel, N. Lambrecht, L. Wang, Y. Tache, Neuroscience Letters, 1/1/2009
• The transcriptomes of purified gastric ECL and parietal cells: identification of a novel pathway regulating acid secretion  
  N. Lambrecht, I. Yakubov, C. Zer, G. Sachs, Physiol Genomics, 1/1/2006
• Identification of the K efflux channel coupled to the gastric H,K ATPase during acid secretion  
  N. Lambrecht, I. Yakubov, D. Scott, G. Sachs, Physiol Genomics, 1/1/2005
• The control of gastric acid and Helicobacter pylori eradication  
  G. Sachs, J.M. Shin, K. Munson, O. Vagin, N. Lambrecht, D.R. Scott, D.L. Weeks, K. Melchers, Aliment Pharmacol Ther, 1/1/2000
• Identification of the site of inhibition by omeprazole of alpha-beta fusion protein of the HK-ATPase using site directed mutagenesis  
  N. Lambrecht, Z. Corbett, D. Bayle, S.J.D. Karlish, G. Sachs, J Biol Chem, 1/1/1998
• Structural aspects of the gastric H,K ATPase: The M5/M6 domain and alpha-beta association  
  D. Melle-Milovanovic, N. Lambrecht, G. Sachs, J.M. Shin, Acta Physiol Scand, 1/1/1998
• Muller:Functional ablation of sensory neurons impairs the healing of acute gastric mucosal damage in rats  
  B.M. Peskar, N. Lambrecht, Th. Stroff, M. Respondek, K.-M, Dig Dis Sci, 1/1/1995
• Nitric oxide as mediator of the gastroprotection by cholecystokinin-8 and pentagastrin  
  Th. Stroff, N. Lambrecht, B.M. Peskar, Europ J Pharmacol, 1/1/1994
• Role of calcitonin gene-related peptide and nitric oxide in the gastroprotective effect of capsaicin  
  N. Lambrecht, M. Burchert, M. Respondek, K. M. Müller, B. M. Peskar, Gastroenterology, 1/1/1993
• Effect of prostaglandins and capsaicin on gastric vascular flow and mucosal injury in endothelin-1-treated rats  
  B. M. Peskar, P. Nowak, N. Lambrecht, Agents and Actions, 1/1/1992
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Abstracts/Posters

• Calpain-1 Contributes to Pain and Organ Damage in Sickle Cell Disease
  Nils Lambrecht, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• An Intimal Cardiac Sarcoma with Overexpression of MDM2, first presented as intestinal obstruction, a case report and review of literature.
  N. Lambrecht, ASCP Online Case Reports; American Society for Clinical Pathology, Chicago, IL, 1/1/2014
• A Case Of Unsuspected Hereditary Hemochromatosis And The Important Role Of Autopsy
  Ali Nael, Sasan Setoodeh, M. DaCosta-Iyer, SA. Deshmukh-Rane, Y. Ouyang, N. Lambrecht, Arch Pathol Lab Med, 1/1/2014
• Mechanisms of Preprandial Ghrelin Release From Mouse Gastric X/A-like Cells - Molecular Basis for Regulation by Insulin.
  Michelle Giffin, Janusz Jawien, Andreas Stengel, Miriam Goebel-Stengel, Nils W. Lambrecht, Gastroenterology, 1/1/2013
• The ghrelin activating enzyme ghrelin-O-acyltransferase (GOAT) is present in the human circulation and expressed dependent on body weight.
  Andreas Stengel, Miriam Goebel-Stengel, Tobias Hofmann, Peter Kobelt, Nils W. Lambrecht, Burghard F. Klapp, Gastroenterology, 1/1/2012
• Exploration of Selective Gene Expression by Rat Gastric Corpus Epithelium
  Miriam Goebel, Andreas Stengel, George Sachs, Nils W. Lambrecht, Gastroenterology, 1/1/2011
• Abdominal Surgery Inhibits Circulating Acyl Ghrelin and Ghrelin-O-Acyltransferase Levels in Rats: Role of the Somatostatin Receptor 2
  Andreas Stengel, Miriam Goebel, Lixin Wang, Nils W. Lambrecht, Almaas Shaikh, Burghard F. Klapp, Jean E. Rivier, Yvette Tache, Gastroenterology, 1/1/2011
• Lipopolysaccharide increases Gastric and Circulating NUCB2/Nesfatin-1 Concentrations in Rats
  Andreas Stengel, Miriam Goebel, Janusz Jawien, Yvette Tache, Nils Lambrecht, Gastroenterology, 1/1/2011
• Comparative Gene Expression Analysis of the Rat Gastrointestinal Tract Epithelia
  Nils W. Lambrecht, Andreas Stengel, Miriam Goebel, George Sachs, Gastroenterology, 1/1/2010
• Differential Distribution of Ghrelin-O-Acyltransferase (Goat) Immunoreactive Cells in the Mouse and Rat Gastric Oxyntic Mucosa
  Miriam Goebel, Andreas Stengel, Lixin Wang, Yvette Tache, George Sachs, Nils W. Lambrecht, Gastroenterology, 1/1/2010
• Blastic Plasmacytoid Dendritic Cell Neoplasm
  Niloufar Reisian, Nils W. Lambrecht, Vignesh Walavalkar, Marie Shieh, Lewis Slater, Arch Pathol Lab Med, 1/1/2010
• Isolation and Transcriptomal Characterization of Endocrine Cells of the Rat Ileum
  Nils W. Lambrecht, Andreas Stengel, Miriam Goebel, Yvette Tache, George Sachs, Gastroenterology, 1/1/2009
• Fasting Decreases Nesfatin-1/NUCB2 Serum Levels in Rats
  Miriam Goebel, Andreas Stengel, Yvette Tache, George Sachs, Nils W. Lambrecht, Gastroenterology, 1/1/2009
• Changes in Rat ECL Cell Gene Expression Due to 24 hr Fasting
  Nils W. Lambrecht, Iskandar Yakubov, George Sachs, Gastroenterology, 1/1/2007
• Pacap Activation of Secretory and Proliferative Signaling Pathways in Bon Cells Is Mediated Through PKA, Calmodulin and RAS
  Sandy N. Lieu, David S. Oh, Nils W. Lambrecht, Iskandar Yakubov, George Sachs, Joseph R. Pisegna, Patrizia M. Germano, Gastroenterology, 1/1/2006
• Identification of a Novel Negative Feedback Regulation of the ECL Cell During Acid Secretion By the Parietal Cell Using Subtractive Hybridization Microarray Gene Expre...
  Nils W. Lambrecht, Iskandar Yakubov, Cindy Zer, George Sachs, Gastroenterology, 1/1/2006
• Expression, Localization and Function of the K Channel Complex [kcnq1, Kcne2] in Parietal Cells
  Nils W. Lambrecht, Iskandar Yakubov, George Sachs, Gastroenterology, 1/1/2005
• Physiological Genomics of the Gastric Parietal Cell
  Nils W. Lambrecht, Iskandar Yakubov, George Sachs, Gastroenterology, 1/1/2004
• The binding region of a novel class of anti-ulcer drugs, the imidazo[1,2 alpha] pyridines, on the gastric H,K-ATPase
  Olga Vagin, Keith Munson, Nils W. Lambrecht, George Sachs, Gastroenterology, 1/1/2001
• Mutational analysis of glutamate 820 of the alpha subunit of the rabbit H,K-ATPase
  Nils W. Lambrecht, Keith Munson, George Sachs, Gastroenterology, 1/1/1999
• Identification of the loop region between TM5 and TM6 of the H,K ATPase using cysteine mutagenesis
  N. Lambrecht, Z. Corbett, D. Bayle, S.J.D. Karlish, G. Sachs, Gastroenterology, 1/1/1998
• Prostagalndins involved in mild irritant-evoked gastroprotection are derived via the cyclooxygenase 2 pathway.
  Britta Gretzer, Nils W. Lambrecht, Karlheinz Ehrlich, M. Chantrain, Brigitta M Peskar, Gastroenterology, 1/1/1997
• Functional expression of the gastric H,K-ATPase as an alpha-beta fusion protein.
  Nils W. Lambrecht, Denis Bayle, Steve J. D. Karlish and George Sachs, Gastroenterology, 1/1/1996
• Is omeprazole resistance due to mutations of cysteine 813 or 822 in the acid pump?
  Luis P. Leite, Nils W. Lambrecht, George Sachs, Donald O. Castell, Per-Olaf Lagerstrom, Gastroenterology, 1/1/1995
• Nitric oxide participates in the regulation of gastric emptying but is not involved in the inhibitory effects of cholecystokinin (CCK)-8 on gastric motility in rats.
  Susanne Plate, Nils W. Lambrecht, Brigitta M Peskar, Gastroenterology, 1/1/1994
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