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Office
1200 Main Street West, Hamilton, Ontario, CANADA L8N 3Z5
HSC 2N49B
Beverly Hills, CA 90210Phone+1 905-521-2100Fax+1 905-521-2655
Summary
- Dr. Nikhil Pai is an Associate Professor in the Division of Pediatric Gastroenterology at McMaster Children’s Hospital. He completed medical school at McMaster University, his pediatric residency at the Hospital for Sick Children (University of Toronto), and his pediatric gastroenterology fellowship at Boston Children's Hospital (Harvard Medical School). He is the Medical Lead of the Complex Pediatric Nutrition Service at McMaster Children's Hospital, and is the Medical Lead of the Pediatric Intestinal Failure program.
His research program focuses on the role of the intestinal microbiome in pediatric inflammatory bowel disease, particularly through the application of fecal microbiota transplantation. He is principal investigator of the PediCRaFT Trial (Pediatric Crohn's Disease Fecal Microbiota Transplant). His research expertise is in clinical, and basic science studies of host-microbial interactions. His lab supports a medium-sized team of trainees and research staff, actively publishes in peer-reviewed journals, and receives support from institutional and federal grants.
Dr. Pai is an active clinician-educator within the Department of Pediatrics, and trains medical students, pediatric residents, and fellows through his busy pediatric gastroenterology inpatient, outpatient and endoscopy practice. He is an Associate Faculty Member of McMaster University's Farncombe Family Digestive Diseases Research Institute, and the Centre for Metabolism, Obesity and Diabetes Research (MODR). His administrative work includes serving as Co-Chair of McMaster Children's Hospital's Pediatric Nutrition Advisory Commmittee, member of the Canadian Pediatric Malnutrition Task Force, and Academic Editor of PLOS One.
Education & Training
- Boston Children’s Hospital//Boston Medical CenterFellowship, Pediatric Gastroenterology, 2011 - 2014
- Michael G. DeGroote School of MedicineClass of 2007
Certifications & Licensure
- PA State Medical License 2010 - 2024
- MA State Medical License 2011 - 2016
- American Board of Pediatrics Pediatric Gastroenterology
Clinical Trials
- PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial Start of enrollment: 2018 Dec 01
Roles: Principal Investigator
- Soluble Fibre Supplementation in NAFLD Start of enrollment: 2022 Sep 09
Roles: Contact, Principal Investigator
- Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth Start of enrollment: 2024 Mar 11
Roles: Contact, Principal Investigator
Publications & Presentations
PubMed
- 272 citationsRole of the microbiome in energy regulation and metabolism.Max Nieuwdorp, Pim W. Gilijamse, Nikhil Pai, Lee M. Kaplan
Gastroenterology. 2014-05-01 - 46 citationsNutrition Support of Children With Chronic Liver Diseases: A Joint Position Paper of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutriti...Marialena Mouzaki, Jiri Bronsky, Girish Gupte, Iva Hojsak, Jörg Jahnel
Journal of Pediatric Gastroenterology and Nutrition. 2019-10-01 - 19 citationsReduction of Central Line-Associated Bloodstream Infections and Line Occlusions in Pediatric Intestinal Failure Patients Receiving Long-Term Parenteral Nutrition Using...Jill Quirt, Christina Belza, Nikhil Pai, Rose-Frances Clause, Filip Markovic
JPEN. Journal of Parenteral and Enteral Nutrition. 2021-08-01
Press Mentions
- McMaster Children’s Hospital Opens First Stool Bank for Kids in CanadaJuly 14th, 2023
Research History
- NEAT Study (Co-Principal Investigator)Prospective cohort study assessing the role of urine metabolite testing in the diagnosis of pediatric inflammatory bowel disease from functional gastrointestinal disorders, and differentiation of pediatric Crohn's disease from Ulcerative colitis.
- PediCRaFT Trial (Principal Investigator)Randomized-controlled clinical trial assessing the feasibility and clinical efficacy of a novel combination colonic and oral fecal microbiota transplant preparation for the treatment of active pediatric Crohn's disease (CD).
Professional Memberships
- North American Society of Pediatric Gastroenterology, Hepatology and NutritionMember
- Member
- Member
- Canadian Association of GastroenterologyMember
External Links
- McMaster Expertshttps://experts.mcmaster.ca/display/pain
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