Nicola Hanania MD MS

PubMed

• The Direct and Indirect Role of IgE on Airway Epithelium in Asthma.
  Christian Domingo, William W Busse, Nicola A Hanania, Muyesser Ertugrul, Lauren A Millette
  Allergy. 2025-04-01
• Asthma outcomes in a safety net hospital system: A comparative study to a national cohort.
  Juan Ortiz, Kristen A Staggers, Muhammad Adrish, Nicola A Hanania, Tianshi David Wu
  Respiratory Medicine. 2025-03-07
• Dupilumab for chronic obstructive pulmonary disease with type 2 inflammation: a pooled analysis of two phase 3, randomised, double-blind, placebo-controlled trials.
  Surya P Bhatt, Klaus F Rabe, Nicola A Hanania, Claus F Vogelmeier, Mona Bafadhel
  The Lancet. Respiratory Medicine. 2025-03-01

Journal Articles

• Care Pathways for the Selection of a Biologic in Severe Asthma  
  Michael E Wechsler, Wanda Phipatanakul, Nicola A Hanania, The European Respiratory Journal
• Executive summary: prevention of acuteexacerbation of COPD: American College of Chest Physicians and Canadian Thoracic Society Guideline  
  Criner GJ, Bourbeau J, Diekemper RL, Ouellette DR, Goodridge D, Hernandez P, Curren K, Balter MS, Bhutani M, Camp PG, Celli BR, Dechman G, Dransfield MT, FielSB, Forem..., Chest, 1/1/2015
• Omalizumab in asthma: an update on recent developments  
  Humbert M, Busse W, Hanania NA, Lowe PJ, Canvin J, Erpenbeck VJ, Holgate S, J Allergy Clin Immunol Pract, 1/1/2014
• The American Lung Association: Asthma Clinical Research Centers network: addressing real life questions in asthma management  
  E.A. Lancet, J. T. Holbrook, R.A. Wise, NA Hanania, Clin. Invest., 1/1/2014
• Blocking KV13 channels inhibits Th2 lymphocyte function and treats a rat model of asthma  
  Koshy S, Huq R, Tanner MR, Atik MA, Porter PC, Khan FS, Pennington MW, Hanania NA, Corry DB, Beeton C, J Biol Chem, 1/1/2014
• The Saudi guidelines for chronic obstructive pulmonary disease: A fresh "Real-World" approach to COPD  
  Hanania NA, Ann Thorac Med, 1/1/2014
• The safety of long-acting beta2-agonists in the treatment of stable chronic obstructive pulmonary disease  
  Decramer ML, Hanania NA, Lotvall JO, Yawn BP, Int J Chron Obstruct Pulmon Dis, 1/1/2013
• Optimizing safety of COPD treatments: role of the nurse practitioner  
  Spencer P, Hanania NA, J Multidiscip Healthc, 1/1/2013
• Ten years of tiotropium: clinical impact and patient perspectives  
  Yohannes AM, Connolly MJ, Hanania NA, Int J Chron Obstruct Pulmon Dis, 1/1/2013
• Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility  
  Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Lang..., Hum Genet, 1/1/2013
• Age-related differences in asthma outcomes in the United States, 1988-2006  
  Tsai CL, Delclos GL, Huang JS, Hanania NA, Camargo CA Jr, Ann Allergy Asthma Immunol, 1/1/2013
• Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, rando...  
  Dransfield MT, Bourbeau J, Jones PW, Hanania NA, Mahler DA, Vestbo J, Wachtel A, Martinez FJ, Barnhart F, Sanford L, Lettis S, Crim C, Calverley PMA, Lancet Respir Med, 1/1/2013
• Evaluating the safety of COPD medications: an evidence-based review  
  Hanania NA, Chest, 1/1/2013
• Exploring the effects of omalizumab in allergic asthma  
  Hanania NA, Wenzel S, Rosen K, Hsieh HJ, Mosesova S, Choy DF, Lal P, Arron JR, Harris JM, Busse W, Am J Respir Crit Care Med, 1/1/2013
• Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma  
  Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa E Silva JR, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Hales JB, McEvoy C, Slebos..., J Allergy Clin Immunol, 1/1/2013
• Age-related differences in clinical outcomes for acute asthma in the United States, 2006-2008  
  Tsai CL, Lee WY, Hanania NA, Camargo CA Jr, J Allergy Clin Immunol, 1/1/2012
• New bronchodilators  
  Mak G, Hanania NA, Curr Opin Pharmacol, 1/1/2012
• Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype  
  Agusti A, Edwards LD, Rennard SI, MacNee W, Tal-Singer R, Miller BE, Vestbo J, Lomas DA, Calverley PM, Wouters E, Crim C, Yates JC, Silverman EK, Coxson HO, Bakke P, M..., PLoS One, 1/1/2012
• Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease  
  Martinez CH, Chen YH, Westgate PM, Liu LX, Murray S, Curtis JL, Make BJ, Kazerooni EA, Lynch DA, Marchetti N, Washko GR, Martinez FJ, Han MK; COPDGene Investigators (H..., Thorax, 1/1/2012
• Methacholine challenge test: diagnostic characteristics in asthmatic patients receiving controller medications  
  Sumino K, Sugar EA, Irvin CG, Kaminsky DA, Shade D, Wei CY, Holbrook JT, Wise RA, Castro M; American Lung Association Asthma Clinical Research Centers (Hanania NA), J Allergy Clin Immunol, 1/1/2012
• The efficacy and safety of the novel long-acting beta2 agonist vilanterol in patients with COPD: a randomized placebo-controlled trial  
  Hanania NA, Feldman G, Zachgo W, Shim JJ, Crim C, Sanford L, Lettis S, Barnhart F, Haumann B, Chest, 1/1/2012
• Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale  
  Al-shair K, Muellerova H, Yorke J, Rennard SI, Wouters EF, Hanania NA, Sharafkhaneh A, Vestbo J; ECLIPSE investigators, Health Qual Life Outcomes, 1/1/2012
• Effect of a primary care continuing education program on clinical practice of chronic obstructive pulmonary disease: translating theory into practice  
  Adams SG, Pitts J, Wynne J, Yawn BP, Diamond EJ, Lee S, Dellert E, Hanania NA, Mayo Clin Proc, 1/1/2012
• Pulmonary arterial enlargement and acute exacerbations of COPD  
  Wells JM, Washko GR, Han MK, Abbas N, Nath H, Mamary AJ, Regan E, Bailey WC, Martinez FJ, Westfall E, Beaty TH, Curran-Everett D, Curtis JL, Hokanson JE, Lynch DA, Mak..., N Engl J Med, 1/1/2012
• Quantitative computed tomography of the lungs and airways in healthy nonsmoking adults  
  Zach JA, Newell JD Jr, Schroeder J, Murphy JR, Curran-Everett D, Hoffman EA, Westgate PM, Han MK, Silverman EK, Crapo JD, Lynch DA; COPDGene Investigators (Hanania NA), Invest Radiol, 1/1/2012
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Books/Book Chapters

• Advances in Geroscience 
  Chapter: Aging and Asthma 
  Hanania NA, Busse PEditors: Sierra F and Kohanski RA.Springer2015
• Gastroesophageal Reflux and the Lung 
  Chapter: GER in Asthma and COPD 
  Akkanti B, Hanania NAEditors: Meyer KC and Raghu G.Humana Press2013
• COPD: Clinical Guide for the Diagnosis and Management 
  Editors: Hanania NA, Sharafkhaneh A.Springer2011
• COPD: Clinical Guide for the Diagnosis and Management 
  Chapter: Pharmacologic Therapy: Bronchodilators 
  Hanania NA, Cazzola MEditors: Hanania NA and Sharafkhaneh AS.Humana Press2011
• Conn’s Current Therapy 
  Chapter: COPD 
  Hanania NA, Sharafkhaneh AEditors: Bope ET, Kellerman RD.Elsevier Saunders2011
• Critical Care Obstetrics 
  Chapter: Acute lung injury and acute respiratory distress (ARDS) during pregnancy 
  Mallampalli A, Hanania NA, Guntupalli KKEditors: Belfort MA, Saade G, Foley MR, Phelan JP, Dildy GA.Blackwell Publishing LimitedEdition 5th,2010
• Atlas of COPD 
  Chapter: Comorbidities of chronic obstructive pulmonary disease 
  Kao C, Hanania NAEditors: Crapo JD.Springer2009
• Therapeutic strategies for Acute COPD Exacerbations 
  Chapter: Future pharmacologic therapy of exacerbations in COPD 
  Hanania NA, Sharafkhaneh ASEditors: Cazzola M, Sethi S, Blasi F, Anzueto A.Clinical Publishing, Oxford2009
• Clinical Asthma 
  Chapter: Bronchodilators: Beta2-agonists and anticholinergics 
  Hanania NA, Cazzola MEditors: Castro M, Kraft M.Mosby Elsevier2008
• Therapeutic Strategies Asthma Current Treatments 
  Chapter: Non-bronchodilator activities of Beta2- agonists 
  Hanania NAEditors: Polosa R, Holgate ST.Clinical Publishing, Oxford2007
• Principles of Critical Care 
  Chapter: Hypothermia 
  Hanania NA, Zimmerman JLEditors: Hall, Schmidt, Wood.McGraw Hill2004
• Tuberculosis 
  Chapter: Endobronchial Tuberculosis 
  Dhillon S, Hanania NAEditors: Sharma.Edition 3rd,2004
• Saunders Manual of Critical Care 
  Chapter: Hypothermia 
  Page 525.0 - 530.0Hanania NAEditors: Kruse JA, Fink MP, Carlson RW.Saunders, Elsevier Science2003
• Environmental Emergencies 
  Editors: Hanania NA.Critical Care Clinics1999
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Abstracts/Posters

• Characteristics Of Elderly And Younger Patients With COPD In The COPDgene Cohort
  A. D. Parulekar, C.-L. Tsai, M. A. Atik, H. Al-Azzawi, A. F. Mohsin, A. Sharafkhaneh, D. L. DeMeo, E. A. Regan, B. J. Make, N. A. Hanania, COPDGene Study Group, Am J Respir Crit Care Med, 1/1/2014
• Characteristics Of Previously Undiagnosed COPD In The COPDgene Cohort
  A. D. Parulekar, M. A. Atik, D. C. Everett, M. S. Gozegir, A. F. Mohsin, E. A. Regan, R. A. Wise, B. J. Make, A. Sharafkhaneh, N. A. Hanania, COPDGene Study Group, Am J Respir Crit Care Med, 1/1/2014
• Factors Affecting Mortality In Very Elderly Patients With Chronic Obstructive Pulmonary Disease (COPD): Results From COVAD (COPD Outcomes From VA Database) Study
  M. B. Nair, A. Spiegelman, N. A. Hanania, A. Sharafkhaneh, Am J Respir Crit Care Med, 1/1/2014
• Impact Of Initiating Nebulized Formoterol Fumarate On Health Outcomes In COPD Patients Who Frequently Use Short-Acting Inhaled beta2-Agonists
  G. Colice, A. Buikema, L. Xie, A. Sharafkhaneh, R. Rodiguez-Roisin, N. Hanania, A. Altman, J. R. Harper, O. Baser, P. Altman, Am J Respir Crit Care Med, 1/1/2014
• Efficacy and safety of lebrikizumab in severe uncontrolled asthma: Results from the lute and verse phase II randomized, double-blind, placebo-controlled trials
  Hanania NA, et al, AAAAI, 1/1/2014
• Effect Of Fluticasone Furoate (ff)/vilanterol (vi) Compared With Vi On COPD Exacerbations: A Pre-Specified Subgroup Analysis
  M. T. Dransfield, P. M. Calverley, J. Bourbeau, P. W. Jones, N. A. Hanania, D. A. Mahler, J. Vestbo, A. Wachtel, F. J. Martinez, F. Barnhart, D. Midwinter, S. Lettis, ..., Am J Respir Crit Care Med, 1/1/2013
• A Large Simple Safety Study of Nebulized Arformoterol Tartrate: Risk of Respiratory-Related Deaths and COPD Exacerbation-Related hospitalizations by Smoking Status, Ag...
  J. Donohue, N. A. Hanania, B. Make, Chest, 1/1/2013
• Improved Health Related Quality of Life Outcomes in Subjects With Moderate to Severe COPD Treated With Nebulized Arformoterol Tartrate: Results From a 52-Week Trial
  J. Donohue, V. Bollu, N.A. Hanania, Chest, 1/1/2013
• A Large Simple Safety Study of Nebulized Arformoterol Tartrate: Incidence and Risk of Protocol-Defined COPD Exacerbations
  N.A. Hanania, J. Donohue, B. Make, Chest, 1/1/2013
• Comorbid Diseases In COPD Impacts Exercise Capacity, Quality Of Life And Dyspnea
  N. Putcha, N. Hansel, C. H. Martinez, M. K. Han, A. E. Williams, C. P. Hersh, R. A. Wise, B. M. Thomashow, N. A. Hanania, R. Casaburi, G. L. Kinney, Y.-I. Kim, G. R. W..., Am J Respir Crit Care Med, 1/1/2013
• A Simplified Severity Staging System For Chronic Obstructive Pulmonary Disease
  W. Checkley, M. G. Foreman, S. P. Bhatt, M. T. Dransfield, M. K. Han, N. A. Hanania, N. Hansel, E. Regan, R. A. Wise, COPDGene Investigators, Am J Respir Crit Care Med, 1/1/2013
• A Long Term Safety Study Of Arformoterol Tartrate In The Maintenance Therapy Of Patients With Moderate To Severe COPD: Incidence Of Respiratory-Related Deaths And COPD...
  J. F. Donohue, N. A. Hanania, B. J. Make, L. Curry, Am J Respir Crit Care Med, 1/1/2013
• A Long Term Safety Study Of Arformoterol Tartrate In The Maintenance Therapy Of Patients With Moderate To Severe COPD: Evaluation Of Lung Function
  B. J. Make, N. A. Hanania, J. F. Donohue, Am J Respir Crit Care Med, 1/1/2013
• Total Mortality Decreased In Last Decade In Patients With Clinical Diagnosis Of COPD
  H. Qureshi, A. Spiegelman, N. A. Hanania, A. Sharafkhaneh, Am J Respir Crit Care Med, 1/1/2013
• A Long Term Safety Study Of Arformoterol Tartrate In The Maintenance Therapy Of Patients With Moderate To Severe COPD: Incidence Of Adverse Events
  N. A. Hanania, J. F. Donohue, B. J. Make, Am J Respir Crit Care Med, 1/1/2013
• Efficacy Of Roflumilast In COPD Patients With Previous Inhaled Corticosteroid And Concomitant Long-Acting beta2-Agonist Treatment
  M. T. Dransfield, N. A. Hanania, U.-M. Goehring, D. Bredenbroker, H. Lakkis, H. Zhu, P. Rowe, P. M. Calverley, Am J Respir Crit Care Med, 1/1/2012
• The Effect of Roflumilast on Lung Function: Pooled Results From Seven 6-Month Studies in Subjects With Moderate-to-Severe COPD
  N.A. Hanania, J. Karpel, U. Goehring, M. Brose, D. Bredenbroker, H. Lakkis, P.Rowe, L.Fabbri, Chest, 1/1/2012
• Respiratory-Associated Adverse Events in the Roflumilast COPD Safety Pool
  G. Ferguson, N.A.Hanania, U.Goehring, H. Mosberg, M. Brose, D. Bredenbroker, H. Lakkis, P. Rowe, Chest, 1/1/2012
• Treatment With Formoterol Fumarate Inhalation Solution (FFIS) Among COPD Patients With High Use of Nebulized Short Acting Beta 2-Agonists (SABAs)
  A.Sharafkhaneh, N.A Hanania, G. Colice, J.Donohue, A. Riedel, J. Kurlander, P. Mastoridis, P. Altman, Chest, 1/1/2012
• Lebrikizumab, An Anti-Il-13 Monoclonal Antibody, Reduces Severe Asthma Exacerbations Over 32 Weeks In Adults With Inadequately Controlled Asthma
  D. McClintock, J. Corren, N. A. Hanania, S. Mosesova, P. Lal, J. R. Arron, M. D. Eisner, J. G. Matthews, Am J Respir Crit Care Med, 1/1/2012
• A Simple Rule To Identify COPD Patients Who May Need Treatment Re-Evaluation Based On SABA Use
  A. Sharafkhaneh, N. A. Hanania, G. L. Colice, J. D. Donahue, A. Altan Riedel, J. Kurlander, P. R. Altman, Am J Respir Crit Care Med, 1/1/2012
• Safety of fluticasone furoate (FF), an inhaled corticosteroid in combination with vilanterol (VI), a long-acting beta agonist in management of COPD exacerbations
  P.M.A. Calverley, M. T. Dransfield, J.Bourbeau, P. Jones, N. A. Hanania, D. A. Mahler, J. Vestbo, A. Wachtel, F. Martinez, F. Barnhart, L. Sanford, S. Lettis, C. Crim, Eur Respir J, 1/1/2012
• Efficacy of the novel inhaled corticosteroid, fluticasone furoate (FF)/long-acting beta2-agonist, vilanterol (VI) combination in reducing COPD exacerbations
  M. T. Dransfield, P. M.A.C. Calverley, J. Bourbeau, P. Jones, N.A. Hanania, D. A. Mahler, J. Vestbo, A. Wachtel, F. Martinez, F. Barnhart, L. Sanford, S. Lettis, C.C. ..., Eur Respir J, 1/1/2012
• Efficacy And Safety Of Roflumilast From The Pivotal Studies In The North American Patient Population
  N. A. Hanania, J. P. Karpel, U.-M. Goehring, M. Brose, D. Bredenbroker, H. Lakkis, P. Rowe, F. J. Martinez, Am J Respir Crit Care Med, 1/1/2012
• Age-Related Differences In The Presentation And Outcomes Of Acute Asthma In The United States, 2006-2008
  C.-L. Tsai, W.-Y. Lee, N. A. Hanania, C. Camargo, Am J Respir Crit Care Med, 1/1/2012
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Lectures

• COPD: A new look at an old disease 
  Yale University, New Haven, CT - 1/1/2005
• An update on COPD 
  Hartford, CT - 1/1/2005
• Achieving Asthma Control 
  Baltimore, MD - 1/1/2005
• Managing COPD 
  Hunt, Texas - 1/1/2005
• Ventilator- Associated Pneumonia 
  San Antonio, Texas - 1/1/2005
• Indoor Air and Asthma 
  Orlando, FL - 1/1/2004
• SIIVA substudies 
  Orlando, FL - 1/1/2004
• The role of formoterol in acute asthma 
  Chicago, IL - 1/1/2004
• Ozone and Asthma 
  San Francisco, CA - 1/1/2000
• Update on Community Acquired Pneumonia 
  Houston, TX - 1/1/2000
• Frontline Management of COPD 
  Beaumont, Texas - 1/1/1999
• Ozone Related Health Issues 
  Houston, Texas - 1/1/1999
• The use of Beta-agonists in Asthma and COPD 
  Humble, Texas - 1/1/1999
• Use of intravenous immunoglobulins in asthma 
  1/1/1999
• Introduction to Clinical Medicine Course: Management of Asthma and COPD 
  1/1/1999
• Acute Respiratory Failure: Asthma Module 
  1/1/1999
• Current Trends in the Management of COPD 
  Toronto, Ontario, Canada - 1/1/1998
• Decreased bone density in asthmatics treated with inhaled corticosteroids 
  Short Hills, New Jersey - 1/1/1998
• Current Concepts in the Treatment of Nosocomial Pneumonia 
  Pittsburgh, Pennsylvania - 1/1/1998
• Management of Community Acquired Pneumonia 
  Pensacola, Florida - 1/1/1998
• Multi disciplinary Care of the Pulmonary Patient, Treatment Options in COPD 
  1/1/1998
• Asthma and Pulmonary Disease Update for Primary Care Provider 
  Mission, Texas - 1/1/1998
• NIH Guidelines for Asthma 
  Mission, Texas - 1/1/1998
• Prevention and Control: Role of Anti-inflammatory Drugs 
  Mission, Texas - 1/1/1998
• COPD and Smoking Cessation 
  Houston, Texas - 1/1/1998
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Other

• COPD in African Americans 
  Hanania NA
  Baylor College of Medicine Healthline - 1/1/2004
• Measures of success for treatment of chronic obstructive pulmonary disease 
  Hanania NA, Medscape CME article
  www.medscape.com
  1/1/2004
• Update on the pharmacologic management of COPD 
  Hanania NA, Medscape CME article
  www.medscape.com
  1/1/2004
• Experto en asma dicta charlas en Puerto Rico 
  Hanania NA
  www.consalud.com
  1/1/2004
• Emphysema in women 
  Hanania NA, Baylor Healthline
  1/1/2003
• Expert interview: Treatment of chronic obstructive pulmonary disease. A changing paradigm 
  Hanania NA, An expert interview with Nicola A. Hanania, MD, FCCP, Medscape article
  www.medscape.com
  1/1/2003
• FDA alerts asthmatics to drug safety 
  Hanania NA, Nature Reviews: Drug Discovery, News article
  1/1/2003
• Inhaled glucocorticoids as monotherapy in asthma 
  Agrawal A, Hanania NA, Harrison’s Online
  1/1/2002
• Asthma and heartburn 
  Hanania NA, Baylor Healthline
  1/1/2002
• Taking asthma medications every day 
  Hanania NA, Baylor Healthline
  1/1/2002
• Add-on therapy for asthma: leukotriene modifiers vs. long-acting beta2-agonists 
  Hanania NA, Castro M, Harrison’s Online
  1/1/2002
• Smoking and COPD 
  Hanania NA, Baylor Healthline
  1/1/2001
• Ozone and Asthma 
  Hanania NA, Baylor Healthline
  1/1/2001
• Ask the Doctor: COPD 
  Hanania NA, Easy Dose it Gazette, American Lung Association of Texas
  1/1/2001
• 5 Myths about air pollution in the Houston Region – that could be costing us our lives 
  Hanania NA, American Lung Association, Houston and Southeast Texas Region (Newspaper/Print Feature)
  1/1/2001
• Influenza vaccinations in patients with asthma 
  Hanania NA, Baylor Healthline
  1/1/2000
• Asthma in the African Americans 
  Hanania NA, Baylor Healthline
  1/1/2000
• Children are at high risk of exposure to high levels of ozone 
  Hanania NA, Texas Medical Center News
  1/1/1998
• Community Acquired Pneumonia 
  Hanania NA, Baylor Health Channel
  1/1/1998
• Managing Asthma in the Elderly 
  Hanania NA, RT Magazine
  1/1/1997
• Lung Function testing 
  Hanania NA, KUHF Radio/KHOU TV
  Houston - 1/14/2003
• Chronic Obstructive Pulmonary Disease: Current Issue in Management 
  Hanania NA, PeerView CME
  www.peerviewpress.com
  University of Florida - 1/6./2004
• New guidelines summarize treatments for COPD 
  Hanania NA, Reuters Health
  1/25/2004
• Group reports city’s air plagued more by ozone than particles 
  Hanania NA, Houston Chronicle
  1/29/2004
• Distant fires darken skies, raise health concerns 
  Hanania NA, Houston Chronicle
  1/8./2003
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