Nicholas J Pytel DO MS FAAP

Pediatric Hematology & Oncology•Madison, WI

Pediatric Neuro-Oncology

Neuro-Oncology Physician

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600 Highland AveMadison, WI 53792

Summary

Dr. Nicholas ‘Nick’ Pytel is a pediatric oncologist based in Madison, WI. He received his medical degree from Arizona College of Osteopathic Medicine with residency and prior fellowship training at University of Wisconsin Hospitals and Clinics as well as St. Jude Children’s Research Hospital. He specializes in pediatric hematology/oncology and neuro-oncology.

Education & Training

University of TennesseeFellowship, Pediatric Neuro-Oncology, 2021 - 2022
University of Wisconsin Hospitals and ClinicsFellowship, Pediatric Hematology/Oncology, 2017 - 2020
University of Wisconsin Hospitals and ClinicsResidency, Pediatrics, 2014 - 2017
Arizona College of Osteopathic Medicine of Midwestern UniversityClass of 2014, DO, Sigma Sigma Phi
University of WisconsinMS, Biomedical Engineering, 2007 - 2009
University of Illinois at Urbana-ChampaignBS, Materials Science and Engineering , Honors, 2002 - 2006
St. Jude Children's Research HospitalPOE, Pediatric Oncology Research Intern, Top Basic Science Paper

Certifications & Licensure

WI State License 2016 - 2025
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Certificate of Appreciation - Manuscript Reviewer St Jude Children's Research Hospital: Pediatric Oncology Education Program, 2021
Outstanding 2nd Year Pediatric Resident University of Wisconsin Dept of Pediatrics, 2016
1st Place, Basic Science Paper Pediatric Oncology Education Program, 2011
Sigma Sigma Phi National Osteopathic Honor Society, 2011
Silver Pin Award for over 50 hours community service Translating Osteopathic Understanding through Community Health (TOUCH), 2011
Keramos – Materials Science and Engineering Honor Society 2006
Eagle Scout Boy Scouts of America, 1999
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Clinical Trials

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG Start of enrollment: 2023 Oct 01
ACTIVE_NOT_RECRUITING
PHASE1
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
ACTIVE_NOT_RECRUITING
PHASE4
67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma Start of enrollment: 2020 Aug 18
RECRUITING
PHASE1, PHASE2
A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma Start of enrollment: 2021 Feb 16
RECRUITING
PHASE3
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma Start of enrollment: 2020 Jan 31
RECRUITING
PHASE3
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG) Start of enrollment: 2022 May 31
SUSPENDED
PHASE1, PHASE2
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma Start of enrollment: 2020 Jan 15
RECRUITING
PHASE3
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma Start of enrollment: 2020 Feb 20
ACTIVE_NOT_RECRUITING
PHASE2
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Start of enrollment: 2021 Jul 13
RECRUITING
PHASE2
A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors Start of enrollment: 2022 May 10
RECRUITING
PHASE3
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Publications & Presentations

PubMed

Cataract Formation in a Child Receiving Dabrafenib and Trametinib Therapy.
Elaine Botros, Yasmin Bradfield, Nicholas Pytel
Journal of Pediatric Ophthalmology and Strabismus. 2024-09-01
Atypical teratoid/rhabdoid tumour-TYR subtype arising in the setting of germline ring chromosome 22: An uncommon form of tumour predisposition.
Julieann C Lee, Quynh T Tran, Rose B McGee, Melissa R Perrino, Santhosh A Upadhyaya
Neuropathology and Applied Neurobiology. 2024-04-01
2 citations
A CTNNB1-altered medulloblastoma shows the immunophenotypic, DNA methylation and transcriptomic profiles of SHH-activated, and not WNT-activated, medulloblastoma.
Jason Chiang, Daniel C Moreira, Nicholas J Pytel, Yen-Chun Liu, Patrick R Blackburn
Neuropathology and Applied Neurobiology. 2022-08-01

Abstracts/Posters

Three Cases Of Clinically Suspected Cavernomas Found To Have Very Different Pathologies
Nicholas Pytel, Nicholas Harn, Shahriar M Salamat, Kristin Bradley, Raheel Ahmed, Bermans Iskandar, Diane Puccetti, ISPNO 2018, Denver, CO, 6/22/2018
Case report of the natural history of incidentally found medulloblastoma followed radiographically in a young adult with chronic headaches
Pytel, N.J., Bashir, M., Salamat, S., Lulla, R., Patel, N., and Puccetti, D, Society for Neuro-Oncology Conference, San Antonio, TX, 1/1/2015
Structural polymorphism in the N-terminal oligomerization domain of NPM1
Mitrea DM1, Grace CR, Buljan M, Yun MK, Pytel NJ, Satumba J, Nourse A, Park CG, Madan Babu M, White SW, Kriwacki RW, Proc Natl Acad Sci U S A, 1/1/2014
Pre-Pharmacokinetic Studies of Antimalarial Agents
Pytel NJ, Pediatric Oncology Education Program Seminar Series, St. Jude Children’s Research Hospital, Memphis, TN, 1/1/2011
Partially Polymerized Lipidic Vesicles: A Concept Re-invented for Efficient Intracellular Delivery of Macromolecules
Megha Goshi, N.J. Pytel, T. Elbayoumi and M. A. Jordan, Midwestern University Research Day, 1/1/2011
Triggered Growth Factor Release from Dynamic Microspheres via a Protein Conformation Change
W.J. King, N.J. Pytel, K. Ng, and W.L. Murphy, Macromolecular Bioscience, 1/1/2010
Biophysical and Structural Characterization of Interactions Between Nucleophosmin and Arf
N.J. Pytel, C.G. Park, C.R. Grace, and R.W. Kriwacki, Southeastern Magnetic Resonance Conference, Vanderbilt University, Nashville, TN, 1/1/2009
Insights into the Nucleophosmin-Arf Interaction via Structural and Biophysical Approaches
Pytel NJ, Pediatric Oncology Education Program Seminar Series, St. Jude, Memphis, TN, 1/1/2009
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Press Mentions

Kids Color Car to Honor Pediatric Cancer Research at American Family Children’s HospitalSeptember 4th, 2019
Protein's Structural Shift Offers Clues to Tumor Suppression and Other Key Cell FunctionsJuly 2nd, 2014