NathanIvanShapiroMD

Emergency Medicine • Boston, MA

Associate Professor, Medicine-Beth Israel Deaconess Medical Center, Harvard Medical School

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Office
330 Brookline Ave
CC2W
Boston, MA 02215
Phone+1 617-754-2343

Education & Training

Massachusetts General Hospital/Brigham and Women’s Hospital/Harvard Medical SchoolResidency, Emergency Medicine, 1997 - 2000
Lewis Katz School of Medicine at Temple UniversityClass of 1996

Certifications & Licensure

MA State Medical License 1999 - 2025
PA State Medical License 2002 - 2006
RI State Medical License 2005 - 2006
American Board of Emergency Medicine Emergency Medicine

Clinical Trials

The Utility of Ischemia Modified Albumin (IMA) in Sepsis Start of enrollment: 2007 Mar 01
Completed
Endothelium in Severe Sepsis Start of enrollment: 2008 Mar 01
Completed
Assessment of Acute Disease to Reduce Imaging Costs Start of enrollment: 2010 Jan 01
Completed
Not Applicable
Near Infrared Spectroscopy (St02) Start of enrollment: 2009 Jan 01
Completed
Pilot Study of Bevacizumab (Avastin) in Patients With Septic Shock Start of enrollment: 2010 Feb 01
Withdrawn
Not Applicable
Preemptive Resuscitation for Eradication of Septic Shock Start of enrollment: 2011 Sep 01
Completed
Not Applicable
Procalcitonin Monitoring Sepsis Study Start of enrollment: 2011 Dec 01
Completed
Efficacy and Safety of Ularitide for the Treatment of Acute Decompensated Heart Failure Start of enrollment: 2012 Jul 01
Completed
Phase 3
Rapid Administration of Carnitine in sEpsis Start of enrollment: 2013 Jan 01
Completed
Phase 2
Reoxygenation After Cardiac Arrest (REOX Study) Start of enrollment: 2013 Jun 01
Completed
Hematoma Block for Distal Radius Fracture Start of enrollment: 2014 Aug 01
Recruiting
Not Applicable
Biomarkers in Infection Start of enrollment: 2006 Apr 01
Recruiting
Reoxygenation After Cardiac Arrest II (REOX II Study) Start of enrollment: 2016 Apr 01
Completed
Phase 1
Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients Start of enrollment: 2018 Nov 10
Suspended
Early Identification of SEPsis SIGNs in Emergency Department Start of enrollment: 2020 Jul 06
Completed
Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19 Start of enrollment: 2020 Jun 01
Completed
Phase 2
Novel Experimental COVID-19 Therapies Affecting Host Response Start of enrollment: 2021 Jul 15
Completed
Phase 2, Phase 3
Roles: Contact
Pragmatic Trial Examining Oxygenation Prior to Intubation Start of enrollment: 2022 Mar 10
Completed
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

12 citations
Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine?
Alexander T. Limkakeng, Andrew A. Monte, Christopher Kabrhel, Michael A. Puskarich, Laura Heitsch
Academic Emergency Medicine. 2016-10-01
495 citations
Serum Lactate as a Predictor of Mortality in Emergency Department Patients with Infection
Nathan I. Shapiro, Michael D. Howell, Daniel Talmor, Larry A. Nathanson, Alan Lisbon
Annals of Emergency Medicine. 2005-05-01
234 citations
Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest
J. Hope Kilgannon, Alan E. Jones, Joseph E. Parrillo, R. Phillip Dellinger, Barry Milcarek
Circulation. 2011-06-14

Journal Articles

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients with COVID-19
Matthew W Semler, Lindsay M Leither, Derek C Angus, Roy G Brower, Steven Y Chang, John C Eppensteiner, Michael R Filbin, Adit A Ginde, Michelle N Gong, Douglas L Hayde..., JAMA

Press Mentions

For Septic Shock, Another Toss-up Between Emphasizing Vasopressors vs FluidsJanuary 21st, 2023
Symptoms and Recovery Among Adult Outpatients with and Without COVID‐19 at 11 Healthcare Facilities—July 2020, United StatesJanuary 6th, 2021
More About COVID-19: Where Are We Now and Where Are We Headed?November 10th, 2020
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Grant Support

Endothelial Cell Signaling And Microcirculatory Flow In Severe SepsisNational Heart, Lung, And Blood Institute2008–2011