Nancy K Sweitzer MD PhD

Heart Failure & Transplantation

Professor of Medicine, Vice-Chair for Clinical Research, Associate Director, Institute for Clinical and Translational Sciences, Washington University School of Medicine. Editor-in-Chief, Circulation: Heart Failure

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4921 Parkview Pl# DvSaint Louis, MO 63110
Phone+1 314-362-1291
Fax+1 314-362-4278

Education & Training

Mass General Brigham/Brigham and Women's HospitalFellowship, Cardiovascular Disease, 1996 - 1999
University of Wisconsin School of Medicine & Public HealthClass of 1993

Certifications & Licensure

MO State Medical License 2022 - 2026
AZ State Medical License 2014 - 2024
WI State Medical License 2002 - 2015
MA State Medical License 1995 - 2006
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

FAHA American Heart Association
Fellow Heart Failure Society of America
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012
Fellow (FACC) American College of Cardiology
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Clinical Trials

Catheterization Laboratory Study: Acute Responses in Diastolic Heart Failure Start of enrollment: 2005 Feb 01
Completed
Not Applicable
Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation Start of enrollment: 2005 May 01
Completed
Not Applicable
Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure Patients Start of enrollment: 2005 Dec 01
Terminated
Not Applicable
Assessment of Cardiac Functional Reserve in Heart Failure With Preserved Ejection Fraction (HF-PEF) Start of enrollment: 2005 Dec 01
Completed
Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF) Start of enrollment: 2011 Apr 01
Completed
Not Applicable
DCM Precision Medicine Study Start of enrollment: 2016 Jun 07
ACTIVE_NOT_RECRUITING
NA
Angiotensin (1-7) Treatment to Improve Cognitive Functioning in Heart Failure Patients Start of enrollment: 2016 Apr 01
Suspended
Phase 2
Evaluation of the Safety and Efficacy of Ang-(1-7) to Enhance Cognitive Function in Participants Undergoing CABG Start of enrollment: 2017 Jul 20
Suspended
Phase 2
Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF) Start of enrollment: 2020 Sep 21
Completed
Phase 1
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Publications & Presentations

PubMed

Multiregional Implementation Initiative's Impact on Guideline-Based Performance Measures for Patients Hospitalized With Heart Failure: IMPLEMENT-HF.
Andrew J Sauer, Chandler Beon, Sruthi Cherkur, Lynn Mallas-Serdynski, Kathie Thomas
Circulation. Heart Failure. 2025-03-21
Harnessing the Plasma Proteome to Predict Mortality in Heart Failure Subpopulations.
Jessica Chadwick, Michael A Hinterberg, Folkert W Asselbergs, Hannah Biegel, Eric Boersma
Circulation. Heart Failure. 2025-03-07
Assessment of the Sensitivity of a Smartphone App to Assist Patients in the Identification of Stroke and Myocardial Infarction: Cross-Sectional Study.
Amar Dhand, Rama Mangipudi, Anubodh S Varshney, Jonathan R Crowe, Andria L Ford
JMIR Formative Research. 2025-03-03

Journal Articles

Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction
Amil M Shah, Nancy K Sweitzer, Akshay S Desai, James C Fang, Sanjeev Saksena, Bertram Pitt, Sanjiv J Shah, Marc A Pfeffer, Scott D Solomon, ScienceDirect
Sudden Death in Heart Failure with Preserved Ejection Fraction
Scot D. Solomon, Sheila M. Hegde, Nancy K. Sweitzer, Sanjiv J. Shah, James C. Fang, Akshay S. Desai, ScienceDirect

Lectures

Can Proteomics Partition PEF Pathophysiology?
2019 ACC Scientific Session & Expo, New Orleans - 3/18/2019
HFpEF: Why Is My Patient Huffing and Puffing? How Can We Help?
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Young Investigator Awards: Basic and Translational Science
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019

Press Mentions

Tirzepatide Helps in HFpEF Across Spectrum of Obesity SeverityFebruary 12th, 2025
Tirzepatide Cuts Heart Failure Events in People with ObesityNovember 19th, 2024
285. Guidelines: 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure – Question #15 with Dr. Ileana PinaApril 11th, 2023
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Grant Support

Reduced Contractile Reserve: A Therapeutic Target In Heart Failure With Normal EFNational Heart, Lung, And Blood Institute2011–2012
Effect Of Aortic Impedance On Myocardial RelaxationNational Center For Research Resources2006–2007
Mechanisms Of Diastolic Heart Failure In AgingNational Institute On Aging2002–2005
Mechanisms Of Diastolic Heart Failure In AgingNational Institute On Aging2000