NaderNajafianMD

Nephrology • Boston, MA

Assistant Professor of Medicine, Brigham and Women's Hospital

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Office
Brigham and Womans Hospital Immunogenetics Transplant
75 Francis St PBB Adm 1
Boston, MA 02115
Phone+1 617-732-5868

Education & Training

Brigham and Women's Hospital/Massachusetts General HospitalFellowship, Nephrology, 1998 - 2002
University of Iowa Hospitals and ClinicsResidency, Internal Medicine, 1995 - 1998
University of Vienna Faculty of MedicineClass of 1995

Certifications & Licensure

MA State Medical License 1997 - 2026
CA State Medical License 1997 - 2025
FL State Medical License 2013 - 2025
IA State Medical License 1995 - 2002
American Board of Internal Medicine Nephrology

Clinical Trials

Characterization of Immunological Profile of Renal Transplant Patients Undergoing Induction Treatment With Thymoglobulin vs. IL-2 Receptor Antagonist Basiliximab Start of enrollment: 2008 Sep 01
Completed
A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome Start of enrollment: 2017 Sep 19
Withdrawn
Phase 2
A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP) Start of enrollment: 2018 Apr 26
Completed
Phase 1
A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN) Start of enrollment: 2019 Sep 30
Terminated
Phase 2
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Publications & Presentations

PubMed

351 citations
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice
Qing Ding, Melissa Y. Yeung, Geoffrey Camirand, Qiang Zeng, Hisaya Akiba
The Journal of Clinical Investigation. 2011-09-01
68 citations
TIM-1 signaling is required for maintenance and induction of regulatory B cells
Melissa Y. Yeung, Qing Ding, Craig R. Brooks, Sheng Xiao, Creg J. Workman
American Journal of Transplantation. 2015-04-01
22 citations
Glomerular inflammation correlates with endothelial injury and with IL-6 and IL-1β secretion in the peripheral blood.
Ibrahim Batal, Sacha A. De Serres, Bechara Mfarrej, Monica Grafals, Geraldine S. Pinkus
Transplantation. 2014-05-27