NaderNajafianMD

Nephrology • Boston, MA

Assistant Professor of Medicine, Brigham and Women's Hospital

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Office
Brigham and Womans Hospital Immunogenetics Transplant
75 Francis St PBB Adm 1
Boston, MA 02115
Phone+1 617-732-5868

Education & Training

Brigham and Women's Hospital/Massachusetts General HospitalFellowship, Nephrology, 1998 - 2002
University of Iowa Hospitals and ClinicsResidency, Internal Medicine, 1995 - 1998
University of Vienna Faculty of MedicineClass of 1995

Certifications & Licensure

MA State Medical License 1997 - 2026
CA State Medical License 1997 - 2025
FL State Medical License 2013 - 2025
IA State Medical License 1995 - 2002
American Board of Internal Medicine Nephrology

Clinical Trials

Characterization of Immunological Profile of Renal Transplant Patients Undergoing Induction Treatment With Thymoglobulin vs. IL-2 Receptor Antagonist Basiliximab Start of enrollment: 2008 Sep 01
Completed
A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome Start of enrollment: 2017 Sep 19
Withdrawn
Phase 2
A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP) Start of enrollment: 2018 Apr 26
Completed
Phase 1
A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN) Start of enrollment: 2019 Sep 30
Terminated
Phase 2
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Publications & Presentations

PubMed

300 citations
A Novel Mechanism of Action for Anti-Thymocyte Globulin: Induction of CD4+CD25+Foxp3+ Regulatory T Cells
Marta Lopez, Michael R. Clarkson, Monica J. Albin, Mohamed H. Sayegh, Nader Najafian
Journal of the American Society of Nephrology. 2006-10-01
35 citations
THE EMERGING ROLE OF THE TIM MOLECULES IN TRANSPLANTATION
Melissa Y. Yeung, Martina M. McGrath, Nader Najafian
American Journal of Transplantation. 2011-10-01
109 citations
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
Sheng Xiao, Nader Najafian, Jay Reddy, Monica J. Albin, Chen Zhu
The Journal of Experimental Medicine. 2007-07-09