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Office
Eye Institute University of Washington
737 Olive Way 3809
Seattle, WA 98101Phone+1 206-719-8520
Summary
- I am an ophthalmologist with a glaucoma tertiary care subspecialty practice of 37 years. I am passionate about the need to understand the regulation of aqueous outflow in glaucoma, how it fails, and how to restore it. I have had a research laboratory for the past twelve years studying aqueous outflow regulation. Our lab has collaborated with the UW Department of Bioengineering, Keck Microscopy Center, and Nanotechnology Center. We identify dynamically moving valves and chambers in the aqueous outflow system that permit pulsatile aqueous outflow. Using OCT in human subjects, we find tissue stiffening in glaucoma with loss of motion. Motion loss identifies the glaucoma process and can predict diurnal IOP fluctuations not apparent from daytime IOP measurements.
Education & Training
- Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolResidency, Ophthalmology, 1969 - 1972
- University of Washington School of MedicineInternship, Transitional Year, 1967 - 1968
- Harvard Medical School1968
- Washington University in St. Louis School of MedicineClass of 1967
- University of Puget SoundB.A., Chemistry, 1961
Certifications & Licensure
- WA State Medical License 1968 - 2014
- American Board of Ophthalmology Ophthalmology
Awards, Honors, & Recognition
- University of Cincinnati Endowed Glaucoma Lecture-Official UC Glaucoma Lecture Cincinnati Society of Ophthalmology, 2013
- Honorary Named Glaucoma Symposium Lecture-Robert N. Shaffer Lecture American Academy of Ophthalmology & Prevent Blindness America, 2011
- Honorary Keynote Lecture_Stephen A. Obstbaum Honored Lecture American Society of Cataract & Refractive Surgery-Glaucoma Day, 2010
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Publications & Presentations
PubMed
- Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches.Ted S Acott, Michael P Fautsch, Weiming Mao, C Ross Ethier, Alex S Huang
Investigative Ophthalmology & Visual Science. 2024-12-02 - iStent insertion orientation and impact on trabecular meshwork motion resolved by optical coherence tomography imaging.Zhaoyu Gong, Murray A Johnstone, Ruikang K Wang
Journal of Biomedical Optics. 2024-07-01 - 2 citationsTrabecular Meshwork Movement Controls Distal Valves and Chambers: New Glaucoma Medical and Surgical Targets.Murray Johnstone, Chen Xin, Elizabeth Martin, Ruikang Wang
Journal of Clinical Medicine. 2023-10-18
Journal Articles
- Quantification of Pulse-Dependent Trabecular Meshwork Motion in Normal Humans Using Phase-Sensitive OCTMurray Johnstone, MD, Investigative Ophthalmology and Visual Science
- Aqueous Outflow - A Continuum from Trabecular Meshwork to Episcleral VeinsMurray Johnstone, Ronald L Fellman, ScienceDirect
- Noninvasive imaging of pulsatile movements of the optic nerve head in normal human subjects using phase-sensitive spectral domain optical coherence tomography.An, L. Chao, J. Johnstone, M. Wang, R., 1/1/2013
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Books/Book Chapters
Abstracts/Posters
- Optic Nerve Head label-free Microangiography: OCT-based Correlation of Microstructure and Microvasculature in Normal and Open Angle Glaucoma Subjects.An, L. Li, P. Johnstone, M. Wang, R., 1/1/2013
- Microspheres (MS) Perfused into the Anterior Chamber (AC) Enter the Lumen of Cylindrical Structures Spanning Schlemm's canal (SC).Martin, E. Orkney, N. Johnstone, M., 1/1/2013
- Extended-imaging depth (16 mm) Spectral Domain OCT Operating at 1310-nm for Anterior Segment Biometry of the Human Eye.Lan, G. Li, P. An, L. Malchow, D. Johnstone, M. Wang, R., 1/1/2013
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Lectures
- Histologic and Aqueous Vein Studies Predict and Explain Phase-sensitive OCT Evidence of Pulse-induced TM Movement in Monkey and Human EyesARVO SIG Aqueous Humor Dynamics: New Approaches, Seattle - 1/1/2013
- Pulse-induced Trabecular Meshwork Movement in Humans: Characterization by Phase-sensitive OCT (PhSOCT)ARVO New Ideas, Seattle - 1/1/2013
- MIGS-New Schlemm's Canal Glaucoma Surgeries: Rationale, Evolution, Expectations?University of Cincinnati, Cincinnati - 1/1/2013
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Other
- "What Does Viscocanalostomy Do?Johnstone, M.A., Ophthalmology Interactive (CD-ROM)
Glaucoma 2001: Evolution and Revolution. American Academy of Ophthalmology and American Glaucoma S - 1/1/2001 - "Releasable Sutures in Filtering Surgery"Johnstone, M.A., Ophthalmology Interactive (CD-ROM)
Improving Success in Filtering Surgery, Bradford Shingleton Editor Sponsored by Ophthalmology Intera - 1/1/2000 - "Digital Pressure in Postop Glaucoma Management"Johnstone, M.A., Ophthalmology Interactive (CD-ROM)
Glaucoma 2000: Cutting Edge Diagnosis and Therapy. Sponsored by the American Academy of Ophthalmolo - 1/1/2000 - Join now to see all
Press Mentions
- Why I Choose the iStent InjectMarch 12th, 2019
Professional Memberships
- Fellow
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