MoniqueEvangelineHinchcliffMDMS

PubMed

• Gastrointestinal disease in systemic sclerosis: the neglected organ system?
  Zsuzsanna McMahan, John Pandolfino, Harris Perlman, Francesco Del Galdo, Monique Hinchcliff
  Current Opinion in Rheumatology. 2024-11-01
• Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis.
  Ilayda Gunes, Elana Bernstein, Shawn E Cowper, Gauri Panse, Niki Pradhan
  Research Square. 2024-10-15
• Perioral hyaluronidase injection for the treatment of microstomia in systemic sclerosis patients: A retrospective cohort study.
  May Elgash, Sa Rang Kim, Madisen Swallow, Monique Hinchcliff, Kathleen Suozzi
  Journal of the American Academy of Dermatology. 2024-09-21

Journal Articles

• Soluble Biomarkers for Prediction of Vascular and Gastrointestinal Disease Severity in Patients with Systemic Sclerosis  
  Miruna Carnaru, MD, and Monique Hinchcliff, MD, MS, Springer Nature, 2/12/2021
• The Scleroderma Patient-Centered Intervention Network Cohort: Baseline Clinical Features and Comparison with Other Large Scleroderma Cohorts  
  Daniel E Furst, Robert Spiera, Maureen D Mayes, Lorinda Chung, Suzanne Kafaja, Virginia Steen, Shervin Assassi, Monique Hinchcliff, Rheumatology
• Mycophenolate mofetil treatment of systemic sclerosis reduces myeloid cell numbers and attenuates the inflammatory gene signature in skin Journal of Investigative Derm...  
  Hinchcliff M, Toledo DM, Taroni JN, Wood TA, Franks JM, Ball MS, Hoffmann A, Amin SA, Tan AU, Tom K, Nesbeth Y, Lee J, Ma M, Aren K, Carns MA, Pioli PA, Whitfield ML, J Invest Dermatol, 1/31/2018
• Validation of the Brief Fear of Negative Evaluation Scale-II in patients with systemic sclerosis: A Scleroderma Patient-centered Intervention Network Cohort study  
  Fox RS, Kwakkenbos L, Carrier ME, Mills SD, Gholizadeh S, Jewett LR, Roesch SC, Merz EL, Assassi S, Furst DE, Gottesman K, Mayes MD, Thombs BD, Malcarne VL; SPIN Inves..., Arthritis Care Res (Hoboken), 1/6/2018
• Reliability and Validity of the Tender and Swollen Joint Counts and Modified Rodnan Skin Score in Early Diffuse Cutaneous Systemic Sclerosis  
  Gordon JK, Girish G, Berrocal VJ, Zhang M, Hatzis C, Assassi S, Bernstein EJ, Domsic RT, Hant F, Hinchcliff M, Schiopu E, Steen VD, Frech T, Khanna D, J Rheumatol, 1/15/2017
• Abnormal esophageal acid exposure on high-dose proton pump inhibitor therapy is common in systemic sclerosis patients  
  Stern EK, Carlson DA, Falmagne S, Hoffmann A, Carns MA, Pandolfino JE, Hinchcliff M, Brenner DM, Neurogastroenterology and Motility, 1/6/2017
• A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis, pulmonary fibrosis and pulmonary arterial hypertension  
  Taroni JN, Greene CS, Martyanov V, Wood TA, Christmann RB; Farber HW, Lafyatis RA, Denton CP, Hinchcliff ME, Pioli PA, Mahoney JM, Whitfield ML, Genome Med, 1/1/2017
• Contributed equally Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the lifespan  
  Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen C, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M,..., J Exp Med, 1/1/2017
• The association between systemic sclerosis disease manifestations and esophageal high-resolution manometry parameters  
  Kimmel JN, Carlson DA, Hinchcliff M, Carns MA, Aren KA, Lee J, Pandolfino JE, Neurogastroenterol Motil, 1/27/2016
• Esophageal dilatation and interstitial lung disease in systemic sclerosis: A cross-sectional study  
  Richardson C, Agrawal R, Lee J, Almagor O, Nelson R, Varga J, Cuttica MJ, Dematte JD, Chang RW, Hinchcliff ME, Semin Arthritis Rheum, 1/26/2016
• Integrated, Multi-cohort Analysis of Systemic Sclerosis Identifies Robust Transcriptional Signature of Disease Severity  
  Lofgren S, Hinchcliff M, Carns M, Wood TA, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi A, Boin F, Chung L, Fiore..., Journal of Clinical Investigation Insight, 1/22/2016
• Loss of Peristaltic Reserve, Determined by Multiple Rapid Swallows is the Most Frequent Esophageal Motility Abnormality in Patients with Systemic Sclerosis  
  Carlson DA, Crowell MD, Kimmel JN, Patel A, Gyawali CP, Hinchcliff M, Griffing WL, Pandolfino JE, Vela MF, Clin Gastroenterol Hepatol, 1/5/2016
• Calcinosis is associated with digital ulcers and osteoporosis in patients with Systemic Sclerosis: A Scleroderma Clinical Trials Consortium Study  
  Valenzuela A, Gordon J, Rodriguez-Reyna TS, Proudman S, Hsu V, Baron M, Medsger TA, Assassi S, Salazar G, Hinchcliff M, Fiorentino D, Khanna D, Young A, Kahaleh B, Cas..., Semin Arthritis Rheum, 1/2/2016
• Controversies: molecular vs clinical systemic sclerosis classification  
  Johnson SR, Hinchcliff M, Asano Y, J scleroderma Relat Disord, 1/1/2016
• Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients  
  Wu M, Assassi S, Salazar GA, Pedroza C, Gorlova OY, Chen WV, Charles J, Taing ML, Liao K, Wigley FM, Hummers LK, Shah AA, Hinchcliff M, Khanna D, Schiopu E, Phillips K..., Arthritis Res Ther, 1/1/2016
• Tenascin-C drives persistence of organ fibrosis  
  Bhattacharyya S, Wang W, Morales-Nebreda L, Feng G, Wu M, Zhou X, Lafyatis R, Lee J, Hinchcliff M, Feghali-Bostwick C, Lakota K, Budinger GR, Raparia K, Tamaki Z, Varga J, Nat Commun, 1/1/2016
• Survival in SSc-PAH by Serum Autoantibody Status in the Pulmonary Hypertension Assessment and Recognition of Outcomes Registry  
  Hinchcliff ME, Khanna S, Lee J, Podlusky S, Almagor O, Chang RW, Steen VD, Chung L for the PHAROS Investigators, Seminars in Arthritis and Rheumatism, 1/19/2015
• Association between Initial Oral Therapy and Outcomes in Systemic Sclerosis-related Pulmonary Arterial Hypertension: Observations from PHAROS  
  Lammi MR, Mathai SC, Saketkoo L, Domsic RT, Bojanowski C, Furst D, Steen V; PHAROS Investigators: Hinchcliff M, Varga J, Frech T, Hummers L, Hsu V, Chung L, Csuka ME, ..., Arthritis Rheumatol, 1/19/2015
• Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures  
  Taroni JN, Martyanov V, Huang CC, Mahoney JM, Hirano I, Shetuni B, Yang GY, Brenner D, Jung B, Wood TA, Bhattacharyya S, Almagor O, Lee J, Sirajuddin A, Varga J, Chang..., Arthritis Research & Therapy, 1/1/2015
• The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor B Signaling  
  Wei J, Ghosh AK, Chu H, Fang F, Hinchcliff ME, Wang J, Marangoni RG, Varga J, Arthritis Rheumatol, 1/1/2015
• A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-y) gene and systemic sclerosis  
  Marangoni RG, Korman BD, Allanore Y, Dieude P, Armstrong LL, Rzhetskaya M, Hinchcliff M, Carns M, Podlusky S, Shah SJ, Ruiz B, Hachulla E, Tiev K, Cracowski JL, Varga ..., Arthritis Res Ther, 1/1/2015
• Longitudinal evaluation of PROMIS-29 and FACIT-Dyspnea short forms in systemic sclerosis  
  Hinchcliff M, Beaumont JL, Carns M, Podlusky S, Thavarajah K, Varga J, Cella D, Chang RW, J Rheumatol, 1/1/2015
• Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms  
  Mahoney JM, Taroni J, Martyanov V, Wood TA, Greene CS, Pioli PA, Hinchcliff ME, Whitfield ML, PLoS Comput Biol, 1/1/2015
• Serum amyloid A is a marker for pulmonary involvement in systemic sclerosis  
  Lakota K, Carns M, Podlusky S, Mrak-Poljsak K, Hinchcliff M, Lee J, Tomsic M, Sodin-Semrl S, Varga J, PLoS One, 1/1/2015
• Cardiac metabolomics and autopsy in a patient with early diffuse systemic sclerosis presenting with dyspnea: a case report  
  Frech TM, Revelo MP, Ryan JJ, Shah AA, Gordon J, Domsic R, Hant F, Assassi S, Shanmugam VK, Hinchcliff M, Steen V, Khanna D, Bernstein EJ, Cox J, Luem N, Drakos S, J Med Case Rep, 1/1/2015
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Books/Book Chapters

• Scleroderma: From Pathogenesis to Comprehensive Management 
  Chapter: Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis. 
  Hinchcliff M, Whitfield MEdition 2nd,2016
• Scleroderma: From Pathogenesis to Comprehensive Management. 
  Chapter: Generic Patient �Reported Outcome Instruments In Systemic Sclerosis: Patient-Reported Outcomes Information System (PROMIS) and Functional Assessment of Chronic Illness Therapy (FACIT). 
  Hinchcliff M, Cella DEditors: Varga J, Denton C, Wigley F.2012

Abstracts/Posters

• High-throughput Quantitative Histology in Systemic Sclerosis Skin Disease Using Computer Vision.
  Correia C, Saber R, Hoffmann A, Wood TA, Whitfield ML, Hinchcliff M, Mahoney JM, Scleroderma World Congress, Amsterdam, Netherlands, 1/1/2018
• Optimal forced vital capacity and lung diffusion cut-points for associated interstitial lung disease in systemic sclerosis.
  Showalter K, Hoffmann A, Aaby D, Richardson C, Dematte J, Chang RW, Rishi Agrawal R, Lee J, Hinchcliff M, American College of Physicians Residents' and Medical Students' Day, Chicago, IL, 1/9/2016

Lectures

• New Clinical and Research Developments in Systemic Sclerosis 
  Bridgeport Hospital, 2019, Griffin Hospital, 2019 - 1/7/2019
• Academia with a Focus on Research and Work/Life Balance. 
  American College of Rheumatology, Chicago, IL, 2016, 2018 - 1/13/2018
• Translational Research in Systemic Sclerosis. 
  Yale School of Medicine Rheumatology, New Haven, CT - 1/29/2017
• The modified Rodnan skin score. 
  American College of Rheumatology, Chicago, IL - 1/28/2017
• Clinical and research update in systemic sclerosis. 
  Presence St. Joseph Hospital, Chicago, IL - 1/26/2017
• Starting a Career in Translational Research. 
  San Diego, CA - 1/3/2017
• Rheumatology Update for the Primary Care Physician. 
  Rosemont, IL - 1/15/2016
• The Scleroderma Esophagus. 
  Cleveland, OH, 2015; New York University Langone Medical Center, New York, NY, 2015 - 1/12/2015
• Scleroderma. 
  Fontana, WI - 1/31/2014
• SSc intrinsic subset classification in patients that demonstrate clinical improvement during treatment. 
  Boston, MA, 2013; Rome, Italy, 2014 - 1/5/2014
• Essential Role for Alternately-Spliced Tenascin-C and TLR4 in Persistence of Organ Fibrosis. 
  Boston, MA - 1/1/2014
• Novel High-throughput Biomarkers in SSc. 
  San Francisco, CA - 1/23/2013
• Systemic Sclerosis: A Treatable Multi-System Disease. 
  Chicago, IL - 1/22/2013
• The utility of measuring gene expression in skin as a biomarker of systemic sclerosis. 
  Geisel School of Medicine at Dartmouth Medical Center, Hanover, NH, 2012; University of Utah, Salt L - 1/15/2013
• Gene Expression in SSc skin and esophagus provides insights into pathogenesis. 
  University of Alabama Birmingham, Birmingham, AL - 1/7/2013
• Autologous Stem Cell Transplant Outcomes in Systemic Sclerosis: The Northwestern Scleroderma Program experience. 
  Montereggioni, Italy - 1/4/2013
• Gene Expression in Skin: Biomarker Studies. 
  Stanford University, Stanford, CA - 1/23/2012
• Pathogenesis and Treatment of Systemic Sclerosis. 
  Mt. Sinai Hospital, Chicago, IL - 1/15/2012
• Crystalline Arthropathies: other crystals that cause joint pain in addition to gout. 
  Rehabilitation Institute of Chicago Academy, Chicago, IL - 1/28/2011
• The Genetics of Systemic Scleroderma. 
  Chicago, IL - 1/24/2011
• Assessing gene expression before and after mycophenolate mofetil (Cellcept) treatment in skin biopsies from patients with scleroderma: the agony and the ecstasy of RNA... 
  Ann Arbor, MI - 1/1/2011
• Navigating the American College of Rheumatology Annual Scientific Meeting. 
  Atlanta, GA - 1/6/2010
• Raynaud's Phenomenon: not just a medley of color. 
  Northwestern University Feinberg School of Medicine - 1/26/2009
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Other

• Contributed equally. Integrative Cardiac Phenomapping and Skin Genome Expression Analysis Identify Similarities in Pathophysiology in Systemic Sclerosis 
  Hinchcliff M, Frech T, Wood TA, Huang CC, Ryan JJ, Beussink-Nelson L, Ma M, Julia Lee J, Varga J, Chang RW, Whitfield ML, Deo RC, Shah SJ
  https://www.biorxiv.org/content/early/2017/11/03/213678
  1/1/2017