MitchellEricHorwitzMD

PubMed

• 145 citations
  Partially Matched, Nonmyeloablative Allogeneic Transplantation: Clinical Outcomes and Immune Reconstitution
  David A. Rizzieri, Liang Piu Koh, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan
  Journal of Clinical Oncology. 2007-02-09
• 439 citations
  Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes
  Bart L. Scott, Marcelo C. Pasquini, Brent R. Logan, Juan Wu, Steven M. Devine
  Journal of Clinical Oncology. 2017-02-13
• 616 citations
  Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma
  John F. DiPersio, Edward A. Stadtmauer, Auayporn Nademanee, Ivana N. Micallef, Patrick J. Stiff
  Blood. 2009-06-04

Journal Articles

• Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: a phase 1–2 dose de-escalation study  
  Anderlini P, Wu J, Gersten I, Ewell M, Tolar J, Antin J, Adams R, Arai S, Eames G, Horwitz M, McCarty J, Nakamura R, Pulsipher M, Rowley S, Leifer E, Carter S, DiFronz..., Lancet Haematology, 1/1/2015
• Improving the Outcome of Umbilical Cord Blood Transplantation Through Ex Vivo Expansion or Graft Manipulation  
  Horwitz ME, Frassoni F, Cytotherapy, 1/1/2015
• Results of a prospective multicentre myeloablative double-unit cord blood transplantation trial in adult patients with acute leukaemia and myelodysplasia  
  Barker JN, Fei M, Karanes C, Horwitz M, Devine S, Kindwall-Keller TL, Holter J, Adams A, Logan B, Navarro WH, Riches M; the RCI BMT 05-DCB Protocol Team, Br J Haematol, 1/1/2015
• Cardiopulmonary exercise testing prior to myeloablative allo-SCT: a feasibility study  
  Kelsey CR, Scott JM, Lane A, Schwitzer E, West MJ, Thomas S, Herndon Ii JE, Michalski MG, Horwitz ME, Hennig T, Jones LW, Bone Marrow Transplant, 1/28/2014
• Increased BCR responsiveness in B cells from patients with chronic GVHD  
  Allen JL, Tata PV, Fore MS, Wooten J, Rudra S, Deal AM, Sharf A, Hoffert T, Roehrs PA, Shea TC, Serody JS, Richards KL, Jagasia M, Lee SJ, Rizzieri D, Horwitz ME, Chao..., Blood, 1/27/2014
• Umbilical Cord Blood Expansion with Nicotinamide Provides Long-term Multi-lineage Engraftment  
  Horwitz M, Chao N, Rizzieri D, Long G, Sullivan K, Gasparetto C, Chute J, Morris A, McDonald C, Waters-Pick B, Stiff P, Wease S, Peled A, Snyder D, Galamidi Cohen E, S..., J Clin Invest, 1/1/2014
• Reduced-intensity allogeneic transplantation using alemtuzumab from HLA-matched related, unrelated, or haploidentical related donors for patients with hematologic mali...  
  Kanda J, Long GD, Gasparetto C, Horwitz ME, Sullivan KM, Chute JP, Morris A, Shafique M, Li Z, Chao NJ, Rizzieri DA, Biol Blood Marrow Transplant, 1/1/2014
• Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone  
  Sung AD, Grima DT, Bernard LM, Brown S, Carrum G, Holmberg L, Horwitz ME, Liesveld JL, Kanda J, McClune B, Shaughnessy P, Tricot GJ, Chao NJ, Bone Marrow Transplant, 1/1/2013
• A phase I study of arsenic trioxide (trisenox), ascorbic Acid, and bortezomib (velcade) combination therapy in patients with relapsed/refractory multiple myeloma  
  Held LA, Rizzieri D, Long GD, Gockerman JP, Diehl LF, Castro CM, Moore JO, Horwitz ME, Chao NJ, Gasparetto C, Cancer Inves, 1/1/2013
• Outcomes of a 1-day nonmyeloablative salvage regimen for patients with primary graft failure after allogeneic hematopoietic cell transplantation  
  Kanda J, Horwitz ME, Long GD, Gasparetto C, Sullivan KM, Chute JP, Morris A, Hennig T, Li Z, Chao NJ, Rizzieri DA, Bone Marrow Transplant, 1/1/2012
• Preemptive Dosing of Plerixafor Given To Poor Mobilizers on Day 5 of G-CSF Administration  
  Horwitz ME, Chute JP, Gasparetto C, Long G, McDonald C, Morris A, Rizzieri D, Sullivan K, Chao N, Bone Marrow Transplant, 1/1/2012
• Long-term Survival and Late Deaths After Hematopoietic Cell Transplantation for Primary Immunodeficiency Diseases and Inborn Errors of Metabolism  
  Eapen M, Ahn KW, Orchard PJ, Cowan MJ, Davies SM, Fasth A, Hassebroek A, Ayas M, Bonfim C, O'Brien TA, Gross TG, Horwitz M, Horwitz E, Kapoor N, Kurtzberg J, Majhail N..., Biol Blood Marrow Transplant, 1/1/2012
• Differential impact of inhibitory and activating Killer Ig-Like Receptors (KIR) on high-risk patients with myeloid and lymphoid malignancies undergoing reduced intensi...  
  Chen DF, Prasad VK, Broadwater G, Reinsmoen NL, Deoliveira A, Clark A, Sullivan KM, Chute JP, Horwitz ME, Gasparetto C, Long GD, Yang Y, Chao NJ, Rizzieri DA, Biol Blood Marrow Transplant, 1/1/2012
• Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors  
  Horwitz ME, Long G, Holman P, Libby E, Calandra GC, Schriber JR, Bone Marrow Transplant, 1/1/2012
• Nakamura R, Pulsipher MA, Difronzo NL, Confer DL, Eapen M, Anderlini P Fludarabine-based Conditioning for Marrow Transplantation from Unrelated Donors in Severe Aplas...  
  Tolar J, Deeg HJ, Arai S, Horwitz M, Antin JH, McCarty JM, Adams RH, Ewell M, Leifer ES, Gersten ID, Carter SL, Horowitz MM, Biol Blood Marrow Transplant, 1/1/2012
• Immune Recovery in Adult Patients Following Myeloablative Dual Umbilical Cord Blood, Matched Sibling, and Matched Unrelated Donor Hematopoietic Cell Transplantation  
  Kanda J, Chiou LW, Szabolcs P, Sempowski GD, Rizzieri DA, Long GD, Sullivan KM, Gasparetto C, Chute JP, Morris A, McPherson J, Hale J, Livingston JA, Broadwater G, Nie..., Biol Blood Marrow Transplant, 1/1/2012
• Mini test dose of intravenous busulfan (busulfex(R)) in allogeneic non-myeloablative stem cell transplantation, followed by liquid chromatography tandem-mass spectrometry  
  Spasojevic I, da Costa LR, Horwitz ME, Long GD, Sullivan KM, Chute JP, Gasparetto C, Morris A, Chao NJ, Rizzieri DA, Cancer Invest, 1/1/2012
• Reduced Intensity versus Myeloablative Allogeneic Stem Cell Transplantation for the Treatment of Acute Leukemia, Myelodysplastic Syndrome and Acute Lymphoid Leukemia  
  Horwitz ME, Curr Opin Oncol, 1/1/2011
• Stem Cell Transplantation for Adults and Children with Sickle Cell Disease: Progress at a Different Pace  
  Horwitz, M, The Hematologist, 1/1/2011
• Clinical Outcomes following Hematopoietic Stem Cell Transplantation for the Treatment of Mucopolysaccharidosis VI  
  Turbeville S, Nicely H, Rizzo D, Pederson T, Orchard P, Horwitz M; Horwitz E, Veys P, Bonfim C, Al-Seraihy A, Molecular Genetics and Metabolism, 1/1/2011
• Early post transplant (F-18) 2-fluoro-2-deoxyglucose positron emission tomography does not predict outcome for patients undergoing auto-SCT in non-Hodgkin and Hodgkin ...  
  Palmer J, Goggins T, Broadwater G, Chao N, Horwitz M, Beaven A, Sullivan K, Coleman RE, Rizzieri D, Bone Marrow Transplant, 1/1/2011
• "Short course" bortezomib plus melphalan and prednisone as induction prior to transplant or as frontline therapy for nontransplant candidates in patients with previous...  
  Gasparetto C, Gockerman JP, Diehl LF, de Castro CM, Moore JO, Long GD, Horwitz ME, Keogh G, Chute JP, Sullivan KM, Neuwirth R, Davis PH, Sutton LM, Anderson RD, Chao N..., Biol Blood Marrow Transplant, 1/1/2010
• Umbilical Cord Blood Transplantation for Treatment of Non-malignant Disorders  
  Horwitz Mitchell, Chao Nelson, Cellular Therapy and Transplantation, 1/1/2010
• Allogeneic hematopoietic stem cell transplantation for Leukocyte Adhesion Deficiency  
  Qasim W, Cavazzana-Calvo M, Davies EG, Davis J, Duval M, Eames G, Farinha N, Filopovich A, Fischer A, Friedrich W, Gennery A, Heilmann C, Landais P, Horwitz M, Porta F..., Pediatrics, 1/1/2009
• Response and toxicity of donor lymphocyte infusions following T-cell depleted non-myeloablative allogeneic hematopoietic SCT from 3-6/6 HLA matched donors  
  Rizzieri DA, Dev P, Long GD, Gasparetto C, Sullivan KM, Horwitz M, Chute J, Chao NJ, Bone Marrow Transplant, 1/1/2009
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Books/Book Chapters

• Cord Blood Biology, Transplantation, Banking and Regulation 
  Chapter: Umbilical Cord Blood Transplantation for Treatment of Non-malignant Disorders 
  Horwitz M, Chao NEditors: Broxmeyer H.AABB Press, Bethesda MD2011
• Stem Cell Transplantation for Hematologic and other Disorders 
  Chapter: Umbilical Cord Hematopoietic Stem Cell Transplantation 
  Horwitz Mitchell, Chao NelsonEditors: Soiffer R.Humana Press, Totowa NJ2007
• Blood Reviews 
  Chapter: Chronic Graft versus Host Disease 
  Page 15 - 27Horwitz, Mitchell, Sullivan, Keith2006
• Gene Therapy: Therapeutic Mechanisms and Strategies 
  Chapter: Gene Therapy for Hematopoietic Disorders 
  Horwitz ME, Malech HLEditors: Templeton N.S.Marcel Dekker Inc, New York, NY1999
• Hematology 
  Chapter: Stem Cell Transplantation 
  Horwitz M, Dunbar DEditors: Schiffman F.Lippencott-Raven, Philadelphia, PA1998
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Abstracts/Posters

• Evaluation of the Oral SYK Inhibitor Fostamatinib in Patients after Allogeneic Transplantation for Chronic Graft-Versus-Host Disease
  Mitchell E. Horwitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Daily Chlorhexidine Gluconate Bathing Reduces the Rate of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Stem Cell Transplantation
  Mitchell E. Horwitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Geriatric Assessment Identifies Impairments in Younger Candidates for Allogeneic Hematopoietic Stem Cell Transplantation
  Mitchell E. Horwitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd
  Mitchell E. Horwitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Decreased Mortality after the First Year of Allogeneic Hematopoietic Stem Cell Transplant in Recipients of Umbilical Cord Blood Vs. Matched Related or Matched Unrelate...
  Mitchell E. Horwitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Nicord(R) Expanded Hematopoietic Progenitor Cells (HPC) Are Capable of Outcompeting the Unmanipulated (UM) Cord Blood Unit and of Prolonged Myeloid and Lymphoid Engraf...
  Mitchell E. Horwitz, Patrick J. Stiff, Nelson J. Chao, David Rizzieri, Gwynn Long, Keith Sullivan, Cristina Gasparetto, John Chute, Ashley Morris, Carolyn McDonald, St..., Biology of Blood and Marrow Transplant, 1/1/2013
• Surgical Mask Usage Reduces the Incidence of Parainfleunza Virus 3 in Recipients of Stem Cell Transplantation
  Anthony D. Sung, Julia A.M. Sung, Kelly Corbet, Vera Hars, Lan Lan, Gloria Broadwater, Ashley Zanter, John Chute, Cristina Gasparetto, Gwynn Long, David Rizzieri, Keit..., 1/1/2013
• Surgical Mask Usage Reduces the Incidence of Parainfluenza Virus 3 in Recipients of Stem Cell Transplantation
  Anthony D. Sung, Julia A.M. Sung, Kelly Corbet, Gloria Broadwater, Vera Hars, Ashley Zanter, Nelson J. Chao, and Mitchell E. Horwitz, Blood (ASH Annual Meeting Abstracts), 1/1/2012
• NiCord(R) expanded Hematopoietic Progenitor Cells (HPC) are Capable of Prolonged Myeloid and Lymphoid Engraftment Following Myeloablative Dual Umbilical Cord Blood (UC...
  Mitchell E. Horwitz, MD, Nelson J. Chao, MD, David A. Rizzieri, MD, Gwynn D. Long, MD, Keith M. Sullivan, MD, Cristina Gasparetto, MD, John P. Chute, MD, Ashley Morris..., Annual meeting of the American Society of Blood and Marrow Transplantation, San Diego, CA, 1/1/2012
• The Impact of Lymphocyte Subset Recovery at 3 Months on Progression-free survival after Myeloablative Allogeneic Stem Cell Transplantation
  Junya Kanda, MD, David A. Rizzieri, MD, Gwynn D. Long, MD, Cristina Gasparetto, MD, John P. Chute, MD, Keith M. Sullivan, MD, Ashley Morris, PharmD, Jacalyn McPherson,..., Annual meeting of the American Society of Hematology, San Diego, CA, 1/1/2011
• Use of Cyclosporine Is Associated with the Increase in Pre-Engraftment Syndrome After Myeloablative Dual Cord Blood Transplantation
  J. Kanda, L. Kaynar, Y. Kanda, V.K. Prasad, S.H. Parikh, D.A. Rizzieri, G.D. Long, K.M. Sullivan, C. Gasparetto, J.P. Chute, A. Morris, S. Winkel, J. McPherson, J. Kur..., Biology of Blood and Marrow Transplant, 1/1/2011
• Use of cyclosporine is associated with the increase in pre-engraftment syndrome after myeloablative dual cord blood transplantation
  Junya Kanda, MD, Leylagul Kaynar, MD, Yoshinobu Kanda, MD, Vinod K. Prasad, MD, Suhag H. Parikh, MD, David A. Rizzieri, MD, Gwynn D. Long, MD, Keith M. Sullivan, MD, C..., Annual meeting of the American Society of Hematology, San Diego, CA, 1/1/2011
• A Comprehensive Comparison Immune Recovery In Adult Patients Following Allogeneic Umbilical Cord Blood, Matched Sibling and Matched Unrelated Donor Stem Cell Transplan...
  Lun-Wei Chiou, Junya Kanda, Paul Szabolcs, Gregory E. Sempowski, Jeffrey Hale, Donna Niedzwiecki, Gloria Broadwater, Nelson J. Chao, and Mitchell E. Horwitz, Blood (ASH Annual Meeting Abstracts), 1/1/2010
• Adult Dual Umbilical Cord Blood Transplantation Using Myeloablative Total Body Irradiation (1350cGy) and Fludarabine Conditioning
  Junya Kanda, David A. Rizzieri, Cristina Gasparetto, Gwynn D. Long, John P. Chute, Keith M. Sullivan, Ashley Morris, Clayton A. Smith, Donna E. Hogge, Janet Nitta, Kev..., Blood (ASH Annual Meeting Abstracts), 1/1/2010
• Efficacy and Safety of Hematopoietic Stem Cell Remobilization with Plerixafor (Mozobil(R)) + G-CSF In Adult Patients with Non-Hematologic Malignancies
  Mitchell E. Horwitz, Edward Gorak, Peter Holman, Edward Libby, Dirk Huebner, Purvi D Mody, and Jeffrey R. Schriber, Blood (ASH Annual Meeting Abstracts), 1/1/2010
• Plerixafor Given “Just In Time” For Peripheral Blood Stem Cell Mobilization Of Patients With Suboptimal Response To G-CSF
  M. Horwitz, T. Khan, G. Long, C. Gasparetto, K. Sullivan, J. Chute, D. Rizzieri, S. Drago, N. Chao, Biology of Blood and Marrow Transplant, 1/1/2010
• Polyoma Virus Is The Principal Cause Of Cystitis Following Alemtuzumab-Based Allogeneic Stem Cell Transplantation
  T. Khan, K. Richard, G. Broadwater, S.E. Hemphill, M. Lassiter, M.E. Horwitz, Biology of Blood and Marrow Transplant, 1/1/2010
• Survival Following Allogeneic Stem Cell Transplantation for Congenital Immunodeficiency and Metabolic Disorders
  M.E. Horwitz, G. Tunes da Silva, M. Eapen, E.M. Horwitz, Biol Blood Marrow Transplant, 1/1/2009
• Total Body Irradiation 1350cGy/Fludarabine (TBI/FLU) vs Myeloablative Busulfan/Fludarabine (Bu/Flu) Preparation in Adult Recipients of Dual Umbilical Cord Blood (UCB) ...
  Mitchell Horwitz, John Chute, Cristina Gasparetto, Gwynn Long, David Rizzieri, Keith Sullivan, Jackie McPherson, and Nelson Chao, Blood (ASH Annual Meeting Abstracts, 1/1/2008
• Myeloablative Intravenous Busulfan/Fludarabine Conditioning Does Not Facilitate Reliable Engraftment of Dual Umbilical Cord Blood Grafts in Adult Recipients
  Mitchell Horwitz, John Chute, Cristina Gasparetto, Gwynn Long, David Rizzieri, Ashley Morris, Jackie McPherson, Keith Sullivan, and Nelson Chao, Blood (ASH Annual Meeting Abstracts, 1/1/2007
• Fludarabine-based non-myeloablative stem cell transplantation in a patient with sickle cell disease and renal failure
  I. Spasojevic, A. Morris, G. Long, C. Gasparetto, K. Sullivan, J. Chute, M. Telen, N. Chao, D. Rizzieri, M. Horwitz, Biology of Blood and Marrow Transplant, 1/1/2007
• Adult Umbilical Cord Blood Transplantation Following Non-Myeloablative Conditioning; Impact of Increased Cell Dose and 200cGy TBI on Engraftment and Survival
  Mitchell Horwitz, David Rizzieri, Gwynn D. Long, Cristina Gasparetto, Ashley Morris, Keith Sullivan, John Chute, Dawn Marshall, and Nelson Chao, Blood (ASH Annual Meeting Abstracts, 1/1/2006
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Lectures

• Stem Cell Transplant for Bone Marrow Failure Disorders 
  Durham, NC - 1/15/2015
• Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia; Transplant or Not in 1st Complete Remission 
  Asheville, NC - 1/12/2015
• Myelofibrosis; To Transplant or Not? 
  Asheville, NC - 1/11/2015
• Improving the Outcome of UCB Transplantation through Ex Vivo Expansion or Graft Manipulation 
  Clinical Center of the National Institutes of Health, Bethesda, MD - 1/4/2015
• Stem Cell Transplantation for Sickle Cell Disease 
  Raleigh, NC - 1/1/2015
• Research and Progress Session: Stem/Progenitor Cell Expansion and Engraftment 
  1/26/2014
• Adult Umbilical Cord Blood Transplantation; Past, Present and Future 
  University of North Carolina, Chapel Hill, NC - 1/16/2014
• Umbilical Cord Blood Stem Cells Cultured in the Presence of Nicotinamide (NiCord(TM)) Provide Long Term Multi-lineage Engraftment 
  Philadelphia, PA - 1/6/2014
• Adult Umbilical Cord Blood Transplantation; Past, Present and Future Oncology 
  Charlotte, NC - 1/4/2014
• Umbilical Cord Blood Stem Cells Expanded in the Presence of Nicotinamide (NiCord) Provide Long Term Multi-lineage Engraftment 
  Philadelphia, PA - 1/1/2013
• Cord Blood Expansion 
  Alexandria, VA - 1/1/2012
• Current Status of Adult Umbilical Cord Blood Transplantation 
  Duke University Medical Center, Durham, NC - 1/2/2011
• Umbilical Cord Blood Transplantation for Treatment of Adult Patients with Hematologic Malignancies 
  Durham, NC - 1/30/2010
• Transplantation vs. Novel, Less Toxic Approaches to Myelodysplastic Syndrome 
  Asheville, NC - 1/1/2010
• Stem Cell Transplantation for Malignant and Non-Malignant Conditions 
  Eden, NC - 1/1/2008
• Nonmyeloablative Allogeneic Stem Cell Transplantation for Sickle Cell Disease 
  Durham, NC - 1/23/2007
• Clinical Utility of FDG-PET Scanning In Restaging of Lymphoma 
  Hot Springs, VA - 1/1/2005
• Poor Prognosis Non-Hodgkins Lymphoma: How Aggressive to Treat? 
  Asheville, NC - 1/1/2005
• Stem Cell Transplantation for Myelodysplastic Syndrome 
  Asheville, NC - 1/1/2004
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