MitchellHGraysonMD

Pediatric Asthma & Allergic Conditions

Grant Morrow, III, MD, Endowed Chair in Pediatric Research, Professor and Chief, Division of Allergy and Immunology, Department of Pediatrics, Nationwide Children's Hospital - The Ohio State University.

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Office
555 S 18th St
Columbus, OH 43205
Phone+1 614-722-6200

Fax+1 614-722-4423

Summary

Dr. Mitchell Grayson is an allergist/immunologist in Columbus, OH and is affiliated with Nationwide Children's Hospital. He received his medical degree from University of Chicago Pritzker School of Medicine and has been in practice 24 years. He specializes in pediatric asthma & allergic conditions and is experienced in asthma, sinusitis, food allergy, rhinitis, and atopy.

Education & Training

Johns Hopkins UniversityFellowship, Allergy and Immunology, 1998
University of Pennsylvania Health SystemResidency, Internal Medicine, 1995
University of Pennsylvania Health SystemInternship, Internal Medicine, 1993 - 1994
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1993
Knox CollegeB.A., 1985 - 1989

Certifications & Licensure

OH State Medical License 2016 - 2027
WI State Medical License 2008 - 2017
MD State Medical License 1996 - 1998
PA State Medical License 1994 - 1995
American Board of Allergy and Immunology Allergy & Immunology

Awards, Honors, & Recognition

Named one of "America's Top Physicians" Allergy and Immunology, Consumers' Research Council Allergy and Immunology, Consumers' Research Council, 2011
Selected as a Top Allergist/Immunologist, Spotlighted in The Leading Physicians of the World International Association of Healthcare Professionals (IAHCP), 2011
Alain L. deWeck Travel Grant awardee 28th symposium of the Collegium Internationale Allergologicum, 2010
MCW Outstanding Medical Student Teachers Medical College of Wisconsin, 2010
2014 Voted as a "Best Doctor" Best Doctors of America 2009, 2009
Orchid Award Asthma and Allergy Foundation of America, Saint Louis Chapter, 2007
Elected to Fellow American College of Allergy, Asthma and Immunology, 2007
Professor Pro Tempore The University of Mississippi Medical Center School of Medicine, Department of Medicine, 2007
Present Interest Section Award American Academy of Allergy, Asthma, and Immunology, 2004
New Outstanding Volunteer American Lung Association of Eastern Missouri, 2001
Saturday Service Award Washington University's Saturday Neighborhood Health Center, 2001
Pharmacia Fellowship Award 1999
Elected to Fellow American Academy of Allergy, Asthma and Immunology, 1998
Globus Award for Best Clinical Paper Mt. Sinai Journal of Medicine, 1998
Student Summer Research Award National Institutes of Health, 1989
Elected to membership, Phi Beta Kappa 1989
Elected to membership, Sigma Xi 1989
Elected member Collegium Internationale Allergologicum
Super Doctor SuperDoctors.com
Elected member American Society for Clinical Investigation
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Clinical Trials

Innate Immunity and the Allergic Response Start of enrollment: 2012 Mar 01
Completed
Not Applicable
Leukotriene Antagonism in Recruitment of CD49d Expressing Neutrophils in Atopic Subjects Start of enrollment: 2017 Sep 06
Completed
Not Applicable

Publications & Presentations

PubMed

417 citations
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease.
Edy Y. Kim, John T. Battaile, Anand C. Patel, Yingjian You, Eugene Agapov
Nature Medicine. 2008-05-18
57 citations
Granzyme B Regulates Antiviral CD8+ T Cell Responses
Suzan M. Salti, Erin Hammelev, Jenny Grewal, Sreelatha T. Reddy, Sarah J. Zemple
Journal of Immunology. 2011-12-15
180 citations
Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort.
Rosalind J. Wright, Cynthia M. Visness, Agustin Calatroni, Mitchell H. Grayson, Diane R. Gold
American Journal of Respiratory and Critical Care Medicine. 2010-07-01

Journal Articles

CD49d-expressing neutrophils differentiate atopic from nonatopic individuals
Sigua JA, Buelow B, Cheung DS, Buell E, Hunter D, Klancnik M, Grayson MH, J Allergy Clin Immunol, 12/18/2013
Rhinovirus specific IgE can be detected in human sera
Tam JS, Jackson WT, Hunter D, Proud D, Grayson MH, J Allergy Clin Immunol, 11/1/2013
Mice Matter
Kelly BT, Grayson MH, Ann Allergy Asthma Immunol, 1/1/2013
Evidence mounts that viruses drive atopic development
Sigua JA, Grayson MH, J Allergy Clin Immunol, 1/1/2013
Role of Viruses in the Development of Atopic Disease in Pediatric Patients
Cheung DS, Grayson MH, Curr Allergy Asthma Rep, 12/1/2012
Ghosts in the annals: boo!
Grayson MH, Marshall GD Jr, Ann Allergy Asthma Immunol., 7/1/2012
Reflux, Colic, Vomiting and Food Allergies in Young Children
Tam JS, Grayson MH, Pediatrics for Parents, 1/1/2012
Expression of High-Affinity IgE Receptor on Human Peripheral Blood Dendritic Cells in Children
Vasudev M, Cheung DS, Pincsak H, Li SH, Yan K, Simpson P, Dasu T, Grayson MH, PLoS One, 1/1/2012
Cutting edge: CD49d+ neutrophils induce FceRI expression on lung dendritic cells in a mouse model of postviral asthma
Cheung DS, Ehlenbach SJ, Kitchens RT, Riley DA, Thomas LL, Holtzman MJ, Grayson MH, J Immunol, 1/1/2010
Cross-linking IgE augments human conventional dendritic cell production of CCL28
Khan SH, Grayson MH, J Allergy Clin Immunol, 1/1/2010
Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 years after severe respiratory syncytial virus bronchiolitis
Silver E, Yin-DeClue H, Schechtman KB, Grayson MH, Bacharier LB, Castro M, Pediatr Allergy Immunol, 1/1/2009
The lymphotoxin LTa1b2 controls postnatal and adult spleen marginal sinus vascular structure and function
Zindl CL, Kim TH, Zeng M, Archambault AS, Grayson MH, Choi K, Schreiber RD, Chaplin DD, Immunity, 1/1/2009
Dipeptidyl peptidase I (DPPI)-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection
Akk A, Simmons PM, Chan H, Agapov E, Holtzman MJ, Grayson MH, Pham CTN, J Immunol, 1/1/2008
Clinical research: protection of the "vulnerable"?
Park SS, Grayson MH, J Allergy Clin Immunol, 1/1/2008
Pulmonary defense mechanisms against pneumonia and sepsis
Tsai K, Grayson MH, Curr Opin Pulm Med., 1/1/2008
Persistent activation of an innate NKT cell-macrophage immune axis translates respiratory viral infection into chronic inflammatory lung disease
Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit L, Byers D, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, Polenini D, Patt..., Nat Med, 1/1/2008
Respiratory virus and asthma: the role of IgE
Khan SH, Park SS, Sirajuddin IA, Grayson MH, Curr Therapeutics, 1/1/2008
Lung dendritic cells and IgE: the link between virus and atropy
Park SS, Ehlenbach SJ, Grayson MH, Future Microbiol, 1/1/2008
Emerging role of dendritic cells in respiratory viral infection
Grayson MH, Holtzman MJ, J Mol Med., 1/1/2007
Controls for lung dendritic cell maturation and migration during respiratory viral infection
Grayson MH, Ramos MS, Rohlfing MM, Kitchens R, Wang HD, Gould A, Agapov E, Holtzman MJ, J Immunol., 1/1/2007
Chemokine complexity: the case for CCL5
Grayson MH, Holtzman MJ, Am J Respir Crit Care Med, 1/1/2006
Treating asthma in the older-patient: is there a place for leukotriene modifiers?
Grayson MH, Korenblat PE, Drugs Aging, 1/1/2006
"Hit-and-run" effects of paramyxoviruses as a basis for chronic respiratory disease
Holtzman MJ, Shornick LP, Grayson MH, Kim EY, Tyner JW, Patel AC, Agapov E, and Zhang Y, Pediatr Infect Dis J., 1/1/2004
Sepsis Induces Apoptosis and Profound Depletion of Splenic Interdigitating and Follicular Dendritic Cells
Tinsley KM, Grayson MH, Swanson PE, Drewry AM, Chang KC, Karl IE, Hotchkiss RS, J. Immunol, 1/1/2003
Adoptive transfer of apoptotic splenocytes worsens survival while adoptive transfer of necrotic splenocytes improves survival in sepsis--effects mediated by interferon?
Hotchkiss RS, Chang KC, Grayson MH, Tinsley KW, Dunne BS, Davis CG, Osborne DF, Karl IE, Proc Natl Acad Sci USA, 1/1/2003
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Press Mentions

Those with Asthma Not at Greater Risk for Severe Disease from COVID-19April 19th, 2022
High Demand for Drug to Prevent Covid in the Vulnerable, yet Doses Go UnusedMarch 6th, 2022
High Demand for Drug to Prevent COVID-19 in the Vulnerable, yet Doses Go UnusedMarch 5th, 2022
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Grant Support

Targeting CCL28 as therapy for obstructive lung diseaseNational Institute of Allergy and Infectious Diseases (NIAID)2016–2019
Mechanisms of atomic disease development in the lungNational Heart, Lung, and Blood Institute (NHLBI)2015–2019
Development of new drugs for asthma by targeting GABA(A) receptors in the lungNational Heart, Lung, and Blood Institute (NHLBI)2014–2018
Dendritic Cells In Atopic And Virus-Induced Airway DiseaseNational Heart, Lung, And Blood Institute2008–2012
Induction Of Food Allergy By Intestinal Dendritic CellsNational Institute Of Allergy And Infectious Diseases2008–2009
Lymphocyte Homing To The SpleenNational Institute Of Allergy And Infectious Diseases2001–2005