MindieH.NguyenMDMAS, FAASLD, AGAF

Hepatology & Liver Transplantation

Professor of Medicine, Director of Hepatology Fellowship, Director of Hepatology Clerkship at Stanford University Medical Center; Chair, AASLD Hepatitis B SIG

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Office
300 Pasteur Dr
Stanford, CA 94305
Phone+1 650-723-4000

Fax+1 650-498-7888

Summary

https://profiles.stanford.edu/mindie-nguyen;
http://med.stanford.edu/nguyenlab.html

Education & Training

University of California (San Diego) Medical CenterChief Residency, Internal Medicine, 1995 - 2006
UCSFMAS, Clinical Research, 2002 - 2004
University of California, San FranciscoM.A.S., Clinical Research, 2002 - 2004
Stanford University Medical CenterChief Fellow, Gastroenterology and Hepatology, 2001 - 2002
Stanford Health Care-Sponsored Stanford UniversityFellowship, Gastroenterology, 1999 - 2002
University of California (San Diego) Medical CenterResidency, Internal Medicine, 1992 - 1995
University of California San Diego School of MedicineClass of 1992
UCIBS, Biological Sciences, Magna Cum Laude, 1984 - 1988
University of California, IrvineB.S., Biological Sciences, Magna Cum Laude, 1984 - 1988

Certifications & Licensure

CA State Medical License 1994 - 2025
American Board of Internal Medicine Gastroenterology
American Board of Internal Medicine Transplant Hepatology

Awards, Honors, & Recognition

Physician Service Award Cardinal Free Clinic, 2013
The Franklin Edbaugh Advising Award for Faculty Stanford University School of Medicine, 2013
Poster of Distinction DDW, 2012
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013
AASLD/Schering Advanced Hepatology Research Fellow Award Stanford University Medical Center, 2001
Excellence in Teaching Award UCSD, 1995
Mabel Wilson Award University of California, Irvine, 1986
Phi Beta Kappa University of California, Irvine, 1985
Southland Scholar Award University of California, Irvine, 1984
Lockheed Management Award University of California, Irvine, 1984
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Clinical Trials

Pegasys and Copegus for Asian Patients With Treatment-naive Hepatitis C Genotypes 6, 7, 8, 9 Start of enrollment: 2004 Oct 01
Completed
Phase 4
Hepatitis B Virus (HBV) Viral Suppression by Entecavir in Adefovir Partial Responders Start of enrollment: 2008 May 01
Completed
Risk Factors and Molecular Genomics of U.S. Patients With Chronic Liver Disease and Hepatocellular Cancer Start of enrollment: 2001 May 01
Completed
Collection of Samples for the Clinical Evaluation of the Aptima HBV (Hepatitis B Virus) Quant (Quantification) Assay Start of enrollment: 2014 Mar 01
Completed
Epidemiologic Study of Hepatocellular Carcinoma in the US Start of enrollment: 2015 Apr 01
Completed
Comparative Efficacy of Fixed-dose Combination Sofosbuvir + Ledipasvir, 8 vs. 12 Weeks in Chronic Hepatitis C Genotype 6 Start of enrollment: 2015 Jun 01
Completed
Phase 4
Safety, Tolerability, and Efficacy of 24 Weeks Simeprevir+Sofosbuvir for Chronic Hepatitis C Genotype 1 Start of enrollment: 2015 Sep 01
Withdrawn
Phase 4
Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF) Start of enrollment: 2018 May 01
Completed
Phase 4
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Publications & Presentations

PubMed

533 citations
Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999–2019: a systematic review and meta-analysis
Jie Li, Biyao Zou, Yee Hui Yeo, Yuemin Feng, Xiaoyu Xie
The Lancet. Gastroenterology & Hepatology. 2019-05-01
437 citations
Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis.
Qing Ye, Biyao Zou, Yee Hui Yeo, Jie Li, Daniel Q. Huang
The Lancet. Gastroenterology & Hepatology. 2020-05-12
49 citations
Ethnic influence on nonalcoholic fatty liver disease prevalence and lack of disease awareness in the United States, 2011–2016
Michael H. Le, Yee Hui Yeo, Ramsey Cheung, Vincent Wai-Sun Wong, Mindie H. Nguyen
Journal of Internal Medicine. 2020-03-04

Journal Articles

Diagnosis Rates of Chronic Hepatitis B in Privately Insured Patients in the United States
Ramsey Cheung, Mindie H Nguyen, JAMA Network Open
Correction to: Hospital Cirrhosis Volume and Readmission in Patients with Cirrhosis in California
Allison J Kwong, Mike Wei, Mindie H Nguyen, Digestive Diseases and Sciences
Clinical Features Associated with Survival Outcome in African-American Patients with Hepatocellular Carcinoma
Jennifer Leong, Lewis Roberts, Myron Schwartz, Mindie H Nguyen, Nature
The Prevalence of Undetectable Vaccine‐Induced Immunity Against Hepatitis B Virus in US Adults at High Risk for Infection
Mindie Nguyen, MD, Hepatology
Oxford University Press Has Registered This DOI Pre-Publication
Mindie H Nguyen, Nghia Nguyen, Oxford University Press
Entecavir Therapy Is Safe And Effective In Patients Previously Treated With Adefovir, Including Those With Adefovir-Resistance
Nguyen NH, Trinh HN, Nguyen TT, Do ST, Tran P, Nguyen HA, Nguyen KK, Garcia RT, Lutchman GA, Nguyen MH, J Gastroetnerol and Hepatol, 1/1/2015
Poorer Long-Term Survival In Patients with Hepatocellular Carcinoma (HCC) Following Left-Sided Compared to Right-Sided Partial Hepatectomy
Valenzuela A, Ha NB, Gallo A, Bonham C, Melcher M, Ahmed A, Kim LH, Esquivel C, Concepcion W, Ayoub WS, Daugherty T, Lutchman GA, Nguyen MH, J Clin Gastroenterol, 1/1/2015
Chronic hepatitis B (CHB) treatment eligibility and actual treatment rates at community gastroenterology clinics and primary care clinics
Nguyen VG, Wan K, Trinh HN, Zhang JQ, Li J, Nguyen MH, J Clin Gastroenterol, 1/1/2015
Meta-analysis: treatment response in patients with chronic hepatitis C genotype 6 compared to those with genotypes 1 treated with pegylated interferon and ribavirin
Nguyen NH, McCormack SA, Yee BE, Chao D, Devaki P, Jencks DS, Nguyen MH, Intervirology, 1/1/2015
Gender Disparity and Real-Life Practice Setting Differences in Actual Treatment Rates of Patients with Chronic Hepatitis B
Kim LH, Nguyen VG, Trinh HN, Li J, Zhang JQ, Ahmed A, Nguyen MH, Dig Dis Sci, 1/1/2014
Similar Virologic Response to Entecavir 05 mg or 10 mg Daily in Treatment-Naïve Chronic Hepatitis B Patients: A Case-Control Study
Ha NB, Ha NB, Chaung KT, Trinh HN, Nguyen HA, Nguyen KK, Nguyen MH, Dig Dis Sci, 1/1/2014
Significantly Higher Long-Term Survival in Hepatocellular Carcinoma Patients in the Post-MELD Era: A Population-Based Cohort Study
Wong RJ, Devaki P, Nguyen L, Cheung R, Cho-Phan C, Nguyen MH, Clin Gastroenterol Hepatol, 1/1/2014
Mutations in HBV DNA Polymerase Associated with Nucleos(t)ide Resistance Are Rare in Treatment-naïve Patients
Vutien P , Trinh HN, Garcia RT, Nguyen HA, Levitt BS, Cooper AD, Keeffe EB, Nguyen K, Daugherty T, Lutchman GA, Ayoub WS, Ahmed A, Garcia G, da Silveira EB, Nguyen MH, Clin Gastroenterol Hepatol, 1/1/2014
Review article: the epidemiology and therapy of chronic hepatitis C genotypes 4, 5 and 6
Wantuck JM, Ahmed A, Nguyen MH, Alimentary Pharmacology & Therapeutics, 1/1/2014
Tenofovir is superior to entecavir for achieving complete viral suppression in HBeAg-positive chronic hepatitis B patients with high HBV DNA
Gao L, Trinh H, Li J, Nguyen MH, Alimentary Pharmacology & Therapeutics, 1/1/2014
Chao DA, Ayoub WS, Lim JK, Nguyen LH, Nguyen MH, Alimentary Pharmacology & Therapeutics, 1/1/2014
Tenofovir is superior to entecavir in HBeAg-positive chronic hepatitis B patients
Gao L, Trinh H, Li J, Nguyen MH, Aliment Pharmacol Ther, 1/1/2014
Apoptosis and hepatic fibrosis in chronic hepatitis B
Chao D, Nguyen MH, Aliment Pharmacol Ther, 1/1/2014
Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis
Kowdley KV, Gordon SC, Reddy KR, Rossaro L, Bernstein DE, Lawitz E, Shiffman ML, Schiff E, Ghalib R, Ryan M, Rustgi V, Chojkier M, Herring R, Di Bisceglie AM, Pockros ..., N Engl J Med, 1/1/2014
Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection
Afdhal N, Zeuzem S, Kwo P, Chojkier M, Gitlin N, Puoti M, Romero-Gomez M, Zarski JP, Agarwal K, Buggisch P, Foster GR, Bräu N, Buti M, Jacobson IM, Subramanian GM, Din..., N Engl J Med, 1/1/2014
Primary Surgical Resection Versus Liver Transplantation for Transplant-Eligible Hepatocellular Carcinoma Patients
Wong R, Wantuck J, Valenzuela A, Ahmed A, Bonham C, Gallo A, Melcher M, Lutchman G, Concepcion W, Esquivel C, Garcia G, Daugherty T, Nguyen MH, Dig Dis Sci, 1/1/2014
Genetic diversity and epidemic history of hepatitis C virus in Ho Chi Minh City, Vietnam
Lu L, Lu T, Yuan M, Li C, Tong W, Xu Y, An Y, Xia W, Pham VH, Vo AXD, Nguyen MH, Abe K, Virology, 1/1/2014
Management of Chronic hepatitis C among Asian Americans
Yip B, Nguyen LH, Nguyen MH, North American Journal of Medicine and Science, 1/1/2014
Access to novel therapeutics for chronic hepatitis C infection in low- and middle-income countries is not only needed but also possible
Jayasekera CR, Barry M, Roberts LR, Nguyen MH, N Engl J Med, 1/1/2014
Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection
Afdhal N, Reddy KR, Nelson DR, Lawitz E, Gordon SC, Schiff E, Nahass R, Ghalib R, Gitlin N, Herring R, Lalezari J, Younes ZH, Pockros PJ, Di Bisceglie AM, Arora S, Sub..., N Engl J Med, 1/1/2014
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Books/Book Chapters

Hepatology: A Practical Approach
Chapter: Benign tumors and evaluation of liver masses.
Nguyen MH, Keeffe EBEditors: Al Knawy B, Schiffman ML, and Wiesner R.Elsevier Science BV, AmsterdamEdition 1st,2005
Gastrointestinal Cancer: A companion to Sleisenger & Fordtran’s GI and liver diseases.
Chapter: Treatment of hepatocellular carcinoma.
Page 605 - 622Nguyen MH, Keeffe EBEditors: Rustgi AK and Crawford J.WB Saunders, Philadelphia, PAEdition 1st,2003
PocketMedicine.com
Chapter: Peritoneal disorders.
Nguyen MH, Keeffe EBEditors: Scharschmidt BF and Keeffe EB.PocketMedicine.com, Inc, Philadelphia, PA2001
PocketMedicine.com
Chapter: Budd-Chiari syndrome and veno-ccclusive disease.
Nguyen MH, Keeffe EBEditors: Scharschmidt BF and Keeffe EB.PocketMedicine.com, Inc2001
PocketMedicine.com
Chapter: Drug & toxin-induced liver disease.
Nguyen MH, Keeffe EBEditors: Scharschmidt BF and Keeffe EB.PocketMedicine.com, Inc2001
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Abstracts/Posters

Lower risk of hepatocellular carcinoma in chronic hepatitis B patients treated with Entecavir: A Reach-B analysis of the Enumerate Study.
Ahn J, Nguyen M, Lee H, Lim J, Pan C, Te H, Tran T, Trinh HN, Lau D, Chu D, Min A, Leduc TS, Pillai A, Bae H, Do S, Mannalithara A, Lok AS, Kim WR on behalf of the ENU..., International Liver Congress, Annual Meeting of the European Association for the Study of Liver Diseases, Vienna, Austria, 1/1/2015
Diagnosis by screening rather than symptoms in HBV-related HCC is associated with improved outcomes, regardless of cirrhosis status but screening history was only pres...
Chen VL, Kim L, Nguyen P, Zhao C, Nguyen MH, International Liver Congress, Annual Meeting of the European Association for the Study of Liver Diseases, Vienna, Austria, 1/1/2015
Gender differences in hepatocellular carcinoma (HCC) surveillance adherence patterns in patients with chronic hepatitis B (CHB) in a multicenter academic and community...
Nguyen L, Wang C, Hoang J, Trinh HN, Li J, Zhang JQ, Nguyen M, International Liver Congress, Annual Meeting of the European Association for the Study of Liver Diseases, Vienna, Austria, 1/1/2015
Meta-analysis: SVR12 with simeprevir and sofosbuvir (SMV+SOF) for 12 weeks in 225 liver transplant (LT) recipients with HCV genotype 1 (HCV-1).
Nguyen NH, Yee BE, Lutchman GA, Lim JK, Nguyen M, International Liver Congress, Annual Meeting of the European Association for the Study of Liver Diseases, Vienna, Austria, 1/1/2015
Outcomes of 12-week therapy with simeprevir+sofosbuvir ±ribavirin (SMV+SOF±RBV): A meta-analysis of 7 studies and 715 HCV genotype1 (HCV-1) patients.
Yee BE, Nguyen NH, Lutchman GA, Lim JK, Nguyen MH, International Liver Congress, Annual Meeting of the European Association for the Study of Liver Diseases, Vienna, Austria, 1/1/2015
Incidence of Hepatocellular Carcinoma (HCC) in a US Cohort of Chronic Hepatitis B(CHB) Patients by Age Gender, Cirrhosis and Antiviral Treatment Status.
Lin, D, Nguyen, N, Hoang, J, Vu, V, Trinh, H, Li, J Zhang, J, Nguyen, K, Nguyen MH, Hepatology; Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, 1/1/2014
Tenofovir (TDF) Monotherapy is Comparable to Tenofovir and Entecavir (TDF+ETV) Combination Therapy as Rescue Therapy for Patients with Partial Response to ETV: A Multi...
Lu L, Trinh HN, Pan CQ, Han SB, Wong CC, Li J, Chan S, Wong C, Nguyen MH, Gastroenterology; Digestive Disease Week, Chicago, IL, 1/1/2014
Meta-analysis: Sustained virologic response (SVR) in Asian patients with infection with hepatitis C virus genotype 6 (HCV-6) versus genotype 1 (HCV-1) treated with peg...
Nguyen N, McCormack S, Yee B, Vutien P, Nguyen MH, Gastroenterology; Digestive Disease Week, Chicago, IL, 1/1/2014
Rescue Therapy with Entecavir (ETV) plusTenofovir (TDF) Combination Therapy Compared to ETV Monotherapy in Chronic Hepatitis B (CHB) Patients with Partial Response to ...
O'Brien CG, Ha NB, Trinh HN, Li J, Nguyen HA, Nguyen MH, Gastroenterology; Digestive Disease Week, Chicago, IL, 1/1/2014
Low treatment Rates and Suboptimal Treatment Completion Rates to Hepatitis C Virus (HCV) Therapy: A Real-World Analysis of a Large US Cohort
Vutien P, Kim Y, Brooks L, Livornese R, Nguyen MH, Gastroenterology; Digestive Disease Week, Chicago, IL, 1/1/2014
Gender Disparity And Real-Life Practice Setting Differences In Actual Treatment Of Patients With Chronic Hepatitis B Meeting Criteria For Antiviral Therapy.
Kim LH, Nguyen VG, Trinh HN, Li J, Zhang JQ, Nguyen MH, Journal of Hepatology; International Liver Congress, Annual Meeting of the European Association for the Study of Liver Diseases, London, United Kingdom, 1/1/2014
Retreatment of Patients with Chronic Hepatitis C Genotype 4 (HCV-4) Infection With Pegylated Interferon and Ribavirin (P/R): A Systematic Review and Meta-Analysis.
Zhang B, Yee B, Nguyen N, Yip B, Ayoub W, Nguyen MH, Lutchman GL, Am J Gastroenterol, 1/1/2014
Sustained Virological Response (SVR) to Standard Interferon (IFN) or Pegylated Interferon (PEG IFN) and Ribavirin (RBV) in Patients with Hepatitis C Virus Genotype 5 (...
Devaki P, Jencks DS, Marupakula V, Nangia S, Nguyen MH, Gastroenterology, 1/1/2014
Meta-analysis: Sustained virologic response (SVR) in patients with infection with hepatitis C virus genotype 5 (HCV-5) versus genotype 1 (HCV-1) and HCV genotype 2/3 (...
Devaki P, Jencks DS, Nangia S, Marupakula V, Nguyen MH, Gastroenterology, 1/1/2014
Compared to HCC patients with chronic viral hepatitis (viral HCC), HCC patients with nonviral etiologies (nonviral HCC) were less likely to undergo HCC screening, pres...
Jencks DS, Kim LH, Wang C, Njie S, Hoang J, Wantuck JM, Nguyen MH, Gastroenterology, 1/1/2014
Gender Disparity and Real-Life Practice Setting Differences in Actual Treatment of Patients with Chronic Hepatitis B Who Met Criteria for Antiviral Therapy.
Kim LH, Nguyen VG, Trinh HN, Li J, Zhang JQ, Nguyen MH, Gastroenterology, 1/1/2014
Predictors for Meeting Criteria to Initiate Antiviral Therapy in U.S. Patients with Chronic Hepatitis B in Diverse Practice Settings
Kim LH, Nguyen VG, Trinh HN, Li J, Zhang JQ, Nguyen MH, Gastroenterology, 1/1/2014
Longer therapy with 48 weeks of pegylated interferon and ribavirin (PEG IFN+RBV) is superior to 24 weeks in patients with treatment-naive hepatitis C virus genotype 6 ...
Nguyen N, McCormack S, Yee B, Nguyen MH, Gastroenterology, 1/1/2014
High Normal ALT and Borderline HBV DNA Were Predictors for Future Treatment Eligibility in Chronic Hepatitis B (CHB) Patients Who Initially Did Not Meet Criteria.
Uribe LA, Nguyen N, Nguyen LH, Kim, Lily H, Trinh HN, Wong CC; Wong C, Nguyen MH, Gastroenterology, 1/1/2014
Differences in Subsequent Eligibility for Antiviral Therapy in Patients with Chronic Hepatitis B (CHB) at Different Real-Life Clinical Settings.
Uribe LA, Nguyen N, Nguyen LH, KimLH, Trinh HN, Wong CC, Wong C, Nguyen MH, Gastroenterology, 1/1/2014
More Frequent Clinic Visits May Improve Adherence to Screening for Hepatocellular Carcinoma (HCC) in Patients with Chronic Hepatitis B (CHB) with and without Cirrhosis.
Wang C, Wong C, Vu V, Trinh HN, Njie S, Hoang J, Nguyen L, Nguyen MH, Gastroenterology, 1/1/2014
Poor Adherence to Screening for Hepatocellular Carcinoma (HCC) in Chronic Hepatitis B (CHB) Patients in Community Gastroenterology and University Liver Clinics.
Wang C. Vu V, Wong C, Trinh HN, Hoang J, Njie S, Nguyen L, Nguyen MH, Gastroenterology, 1/1/2014
Entecavir Safety and Effectiveness in a National Cohort of Chronic Hepatitis B Patients in the United States – the ENUMERATE study.
Ahn, J, Lee,H, Lim, J, Pan C, Nguyen, MH, Kim W, Trinh, H, Tran, T, Chu, D, Min, A, Do S, Woog, J, Mannalithara, M, Lok, A on behalf of the Asian Health Foundation (AHF), Hepatology, 1/1/2014
Incidence of Hepatocellular Carcinoma in a National Cohort of Chronic Hepatitis B Patients on Long Term Entecavir Treatment- the Enumerate study.
Ahn, K, Lim, J, Lee, H, Pan, C, Nguyen, MH, Trinh, H, Tran, T, Chu, D, Min A, Do S, Woog, J, Mannalithara, A, Lok,A, Kim W on behalf of the Asian Health Foundation (AHF), Hepatology, 1/1/2014
Similar Renal Function Profile in Chronic Hepatitis B (CHB) Patients Treated with Tenofovie (DF) vs. Entecavir (ETV) Monotherapy – A Multicenter Matched Case Cohort St...
Ha, N, Ku K, Ha, N, Chaung, K, Trinh, H, Nguyen, MH, Hepatology, 1/1/2014
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Lectures

Training of students and physicians in liver disease among Vietnamese population.
Boston, MA - 1/11/2014
HCP: Low treatment initiation rates and low treatment persistency in patients treated with PEG IFN+RBV based therapy in pre-and post-protease inhibitor eras.
1/5/2014
Chronic hepatitis B.
San Jose, CA - 1/1/2009
Hepatitis B and Liver Cancer.
San Jose, CA - 1/1/2005
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Other

KNTV: Baby Boomers Urged to Take Hepatitis C Test (HCV Screening with Brian Williams)
Nguyen MH
http://www.nbcbayarea.com/news/local/Baby-Boomers-Urged-to-Take-Hepatitis-C-Test-212850911.html
1/24/2013
Hepatocellular carcinoma.
Nguyen MH, Song Manh “Healthy Living”
1/1/2004
Colon Cancer Screening: Who and How
Nguyen MH, KTSF Channel 36, Vietnamese Journal Program, Fall
San Francisco, CA - 1/1/2003
Screening for Liver Cancer and Liver Diseases in Asian-Americans
Nguyen MH, KTSF Channel 36, Vietnamese Journal Program, Fall
San Francisco, CA - 1/1/2003
Guidelines for Preventing and Treating Opportunistic Infections in HIV-Infected Adults and Adolescents - 2008: Recommendations from the National Institutes of Health, ...
Nguyen MH, Member of the Opportunistic Infection/HIV Working Group
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Press Mentions

HCV Elimination Represents ‘Win-Win-Win’ for Patients, Public Health, Cost SavingsMarch 20th, 2023
Strong Support to Provide DAA Therapy to All Patients with HCVJanuary 10th, 2023
Hepatitis C Treatment Rate Remains Low, Despite EfficacyDecember 19th, 2022
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