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Office
3500 Gaston Avenue
Dallas, TX 75246
Summary
- Milton Packer, MD, is an internationally recognized clinical investigator who has made many seminal contributions to the field of heart failure, both in understanding its mechanisms and defining its rational management.
Dr. Packer’s work has spanned nearly 40 years and has been strongly supported by numerous investigator-initiated grants from the NIH and from industry.
His research established the cornerstone of the current modern treatments for heart failure, for which he was the recipient of the Lewis Katz lifetime achievement award in cardiovascular research.
Dr. Packer is also widely recognized for his outstanding leadership abilities, having led the Division of Circulatory Physiology at Columbia University for 12 years, which he built into the nation’s most outstanding research group devoted to heart failure. He has been the principal investigator of more than 15 large international multicenter trials.
Dr. Packer has served frequently as a member of government advisory committees, study sections, task forces or Data and Safety Monitoring Boards for the NIH. He served as a member of the Cardiac and Renal Drugs Advisory Committee to the US Food and Drug Administration from 1986-1992 and then as its Chair from 1997-2001, and he continues to serve on various FDA advisory committees.
Dr. Packer was President of the Heart Failure Society of America from 2000-2002 and has served on numerous guidelines and standards committees for the American Heart Association and American College of Cardiology. He has received many teaching awards and has mentored dozens of young clinical investigators, many of whom have become leaders in basic and clinical research.
Dr. Packer spent most of his career in New York City, where he was the Dickinson Richards Professor and Chief of the Division of Circulatory Physiology at Columbia University. From 2004 until 2015, he was Professor and Chair of the Department of Clinical Sciences at the University of Texas Sou
Education & Training
- Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1973
- Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital/NYC Health and Hospitals (Elmhurst)Fellowship, Cardiovascular Disease
Certifications & Licensure
- TX State Medical License 2009 - 2020
- NY State Medical License 1975 - 2019
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Lewis Katz lifetime achievement award
- Elected Member The American Society for Clinical Investigation, 1992
- Fellow (FACC) American College of Cardiology
Clinical Trials
- Study of DITPA in Patients With Congestive Heart Failure Start of enrollment: 2004 Dec 01
- PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing Start of enrollment: 2007 Jan 01
Publications & Presentations
PubMed
- 57 citationsSGLT2 inhibitors: role in protective reprogramming of cardiac nutrient transport and metabolism.Milton Packer
Nature Reviews. Cardiology. 2023-07-01 - 21 citationsGlucagon-like peptide 1 receptor agonists in patients with type 2 diabetes with and without chronic heart failure: A meta-analysis of randomized placebo-controlled out...João Pedro Ferreira, Francisca Saraiva, Abhinav Sharma, Francisco Vasques-Nóvoa, António Angélico-Gonçalves
Diabetes, Obesity & Metabolism. 2023-06-01 - 6 citationsAlleviation of functional iron deficiency by SGLT2 inhibition in patients with type 2 diabetes.Milton Packer
Diabetes, Obesity & Metabolism. 2023-05-01
Journal Articles
- Growth Differentiation Factor‐15 Is Not Modified by sacubitril/valsartan and Is an Independent Marker of Risk in Patients with Heart Failure and Reduced Ejection Fract...Milton Packer, Scott D Solomon, Michael R Zile, European Journal of Heart Failure
- Effects of Sacubitril/Valsartan on Physical and Social Activity Limitations in Patients with Heart FailureMilton Packer, Alvin Chandra, Akshay S. Desai, Martin P Lefkowitz, Martin P. Lefkowitz, Milton Packer, Michael R. Zile, Scot D. Solomon, Michael R Zile, Alvin Chandra,..., JAMA
- Worsening Heart Failure During the Use of DPP-4 InhibitorsMilton Packer, MD, ScienceDirect
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Lectures
- Patient Selection for MitraClip in Heart Failure With FMR: What Are the “COAPT Criteria” and Where (if Anywhere) Might They Be Stretched?CRF Transcatheter Cardiovascular Therapeutics - Annual Symposium 2019 - Miami, FL - 9/26/2019
- Proportional vs. Disproportional Mitral Regurgitation — The New ParadigmCRF Transcatheter Valve Therapy (TVT) - Structural Heart Disease Summit - Chicago, IL - 6/14/2019
- Learning from Recent Clinical Trials2019 ACC Scientific Session & Expo, New Orleans - 3/18/2019
Authored Content
- The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure — NEJMMay 1996
Press Mentions
- L.A. County Resident Physicians and Fellows Are Poised to StrikeMay 27th, 2022
- Why Are Physicians Silent About Outrageous Drug Prices?January 12th, 2022
- Secondary Mitral Regurgitation: COAPT Inclusion Criteria Helpful in M-TEER Patient SelectionDecember 7th, 2021
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Committees
- member, guidelines and standards committees for the American Heart Association and American College of Cardiology 2000 - 2002
- member, FDA advisory committees 1997 - 2001
- member, Cardiac and Renal Drugs Advisory Committee to the US Food and Drug Administration 1986 - 1992
- member, Government advisory committees on Data and Safety Monitoring Boards for the NIH
Professional Memberships
- Member
- Heart Failure Society of America - 2000-2002President
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