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Office
75 Francis St
# Brigham
Boston, MA 02115Phone+1 617-732-6245
Summary
- I am the Vice Chair for Clinical Pathology and Quality, the Director of the Brigham and Women’s Hospital (BWH) and Dana Farber Cancer Institute (DFCI) Clinical Laboratories, and an Associate Professor of Pathology at Harvard Medical School. The BWH and DFCI clinical laboratories include over forty licensed laboratory sites performing more than 10 MM tests annually with combined revenues of over $ 500 MM and featuring state-of-the-art lab automation and robotics and advanced molecular diagnostics capabilities. Our labs were recently recognized by the Institute of Medicine’s Roundtable on Value and Science-Driven Health Care as an example of increased system efficiency through application of Clinical Lab Automation and LEAN Process Redesign.
I completed my residency training in Clinical Pathology at the BWH in 1993 and I became the Director of the DFCI Clinical Laboratories in 1999 and of both the BWH and DFCI Clinical Laboratories in 2002. My research in the area of cardiac biomarkers as part of the TIMI group led by Dr. Eugene Braunwald, contributed to the worldwide adoption of cardiac troponin-I (cTnI) as the new gold standard for diagnosing and risk-stratifying patients with acute myocardial infarction (AMI) and prompted the redefinition of AMI by the European Society of Cardiology and the American College of Cardiology in 2000. In collaboration with Dr. David Bates, I conducted a series of groundbreaking studies demonstrating the value of a computerized clinical decision support in enhancing the utility of laboratory testing.
I am the co-founder of Cell Imaging Systems Inc., which assigned and licensed its core technology to Constitution Medical, Inc. This technology served as basis for building the Bloodhound™ System, the world's first integrated hematology instrument (www.bloodhoundcbc.com). ROCHE Professional Diagnostics acquired the Bloodhound system in July 2013.
Education & Training
- Boston University School of ManagementMBA, Business Administration, 2004
- Boston University School of MedicineMBA, 2004
- Brigham and Women's HospitalResidency, Pathology-Anatomic and Clinical, 1993
- University Kiril and Metodij Faculty of MedicineClass of 1987, MD
- Saints Cyril and Methodius University of SkopjeMD
Certifications & Licensure
- MA State Medical License 1992 - 2025
- American Board of Pathology Clinical Pathology
Awards, Honors, & Recognition
- Partners in Excellence Award Operational Efficiency 2012
- Partners in Excellence Award for the work of the Advanced Laboratory Diagnostics Steering Committee 2011
- Certificate of Appreciation for an outstanding service 2011
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Publications & Presentations
PubMed
- 214 citationsA randomized trial of a computer-based intervention to reduce utilization of redundant laboratory tests.David W. Bates, Gilad J. Kuperman, Eve Rittenberg, Jonathan M. Teich, Julie M. Fiskio
The American Journal of Medicine. 1999-02-01 - 14 citationsHow SARS-CoV-2 Transformed the Clinical Laboratory: Challenges and Lessons Learned.Jonathan M. Tsai, Nicole V. Tolan, Athena K. Petrides, Sanjat Kanjilal, Manfred Brigl
The Journal of Applied Laboratory Medicine. 2021-04-06 - 55 citationsWhat Proportion of Vancomycin Trough Levels Are Drawn Too Early? Frequency and Impact on Clinical ActionsAileen P. Morrison, Stacy E.F. Melanson, Marcy G. Carty, David W. Bates, Paul M. Szumita
American Journal of Clinical Pathology. 2012-03-01
Journal Articles
- Use of Potassium Concentrations as a Qualityof-Service Metric for Phlebotomists Detects Systematic Preanalytical Biases and Facilitates Their CorrectionGreenblatt MB, Torre M, Means J, Tanasijevic M, Pedulla LV, Bunnell CA, Conrad MJ, Jarolim P, Clin Chem, 1/1/2014
- Significant cost savings achieved by in-sourcing urine drug testing for monitoring medical compliance in pain managementMelanson S, Jarolim P, Snyder M and Tanasijevic M, Clin Chim Acta, 1/1/2013
- An Intervention to Improve the Timing of Vancomycin LevelsMelanson S, Mijailovic AS, Morrison A, Szumita P, Bates DM and Tanasijevic MJ, Am J Clin Path, 1/1/2013
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Abstracts/Posters
- Are specimen collections for Vancomycin trough concentrations appropriately timed?Morrison AP, Tanasijevic, MJ, Carty MG, Szumita P, Melanson SE, American Association for Clinical Chemistry, Anaheim, CA, 1/1/2010
- Biomarkers in Myocardial Injury: Past, Present and Future.Milenko Jovan Tanasijevic, MD, 17th Meeting of the Balkan Clinical Laboratory Federation, 5th Macedonian National Congress of Medical Biochemists, Ohrid, Macedonia, 1/1/2009
- Cardiac troponin assays: A view from the clinical chemistry laboratory.Melanson SEF, Tanasijevic, MJ, Jarolim P, Circulation, American Heart Association, 1/1/2007
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Lectures
- Grand Rounds: "Advanced Diagnostics as Strategy for Success for Academic Clinical Laboratory Programs"ARUP Laboratories, Salt Lake City UT - 9/18/2014
- "Brigham and Women's Clinical Laboratories' Strategy for Advanced Diagnostics."Washington University, Department of Pathology, St. Louis MO - 1/1/2011
- "Strategies for managing reference laboratories testing"Washington University, Department of Pathology, St. Louis MO - 1/1/2011
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Committees
- Member, College of American Pathologists Instrumentation Committee
Professional Memberships
- Member
Industry Relationships
- Scientific Advisor, SynapDx
- Senior Consultant, Integrated Diagnostics, Inc.
- Co-Founder, Cell Imaging Systems, Inc.
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