MichelleLHernandezMD

Pediatric Asthma & Allergic Conditions

Professor of Pediatrics, Division of Allergy and Immunology, University of North Carolina-Chapel Hill School of Medicine. Director, Clinical Research Unit, UNC Children's Research Institute.

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Office
1301 Central Dr
Sanford, NC 27330
Phone+1 919-718-9512

Fax+1 919-718-9516

Summary

I am a board certified pediatrician and allergist/immunologist. My clinical interests are focused on difficult-to-control asthma and other allergic disorders.

My research is focused on identifying pragmatic interventions to treat asthma, and the development of novel technology to enhance asthma care.

Education & Training

University of California (San Diego) Medical CenterFellowship, Allergy and Immunology, 2005 - 2007
University of North Carolina HospitalsResidency, Pediatrics, 2002 - 2005
University of North Carolina at Chapel Hill School of MedicineClass of 2002

Certifications & Licensure

NC State Medical License 2002 - 2025
CA State Medical License 2005 - 2007
American Board of Allergy and Immunology Allergy & Immunology
American Board of Pediatrics Pediatrics

Clinical Trials

Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults Start of enrollment: 2008 May 01
Completed
Phase 1
Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers Start of enrollment: 2005 Oct 01
Completed
Phase 1
In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics Start of enrollment: 2008 Dec 01
Completed
Phase 1
Evaluation of Allergenicity of Hypoallergenic Peanut Product in Peanut Allergic Subjects Start of enrollment: 2011 Dec 01
Completed
Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2 Start of enrollment: 2013 Oct 01
Completed
Not Applicable
Sulforaphane Supplementation in Atopic Asthmatics Start of enrollment: 2013 Apr 01
Completed
Phase 1
Observational Assessment of Baseline Asthma Control in African-American Children Start of enrollment: 2013 Jul 01
Completed
Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy Start of enrollment: 2015 Mar 03
Completed
Phase 1, Phase 2
To Determine the Measurement Properties of the ACT in an African American Adolescent Population With Persistent Asthma Start of enrollment: 2014 Oct 01
Completed
Screening Inhaled Allergen Challenge for Dermatophagoides Farinae Start of enrollment: 2018 Jan 29
Terminated
Early Phase 1
Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Start of enrollment: 2020 Sep 01
Withdrawn
Phase 1, Phase 2
Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation Start of enrollment: 2019 Aug 09
Withdrawn
Phase 1, Phase 2
Woodsmoke Particulate + Hypertonic Saline Start of enrollment: 2019 Aug 01
Enrolling by invitation
Not Applicable
Woodsmoke Particulate + Prednisone Start of enrollment: 2019 Mar 22
Completed
Phase 1, Phase 2
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Publications & Presentations

PubMed

182 citations
Environmental determinants of allergy and asthma in early life
Allison J. Burbank, Amika K. Sood, Matthew J. Kesic, David B. Peden, Michelle L. Hernandez
The Journal of Allergy and Clinical Immunology. 2017-07-01
2 citations
Effect of aeroallergen sensitization on asthma control in African American teens with persistent asthma.
Allison J. Burbank, Shannon C. Grabich, Krista Todorich, Marcia Frye, Ceila E. Loughlin
Annals of Allergy, Asthma & Immunology. 2016-10-01
38 citations
CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice.
Anke Leichtle, Michelle L. Hernandez, Joerg Ebmeyer, Kenshi Yamasaki, Yuping Lai
Journal of Immunology. 2010-03-15

Journal Articles

Review and Feature Article Eosinophilic Granulomatosis with Polyangiitis: Clinical Pathology Conference and Review
Ronald J Falk, Eveline Y Wu, Michelle L Hernandez, ScienceDirect

Press Mentions

Newsworthy from the School of Medicine, Week of August 16 – August 22August 21st, 2024
UNC School of Medicine Experts to Present New Research at AAAAI and SRNT Annual Meetings in San FranciscoFebruary 19th, 2019
Half of US Adults Who Think They Have a Food Allergy Don't. Here's What They Could Have InsteadJanuary 8th, 2019
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Professional Memberships

American Academy of Allergy Asthma and Immunology - AAAAI
Member