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Office
185 Cambridge st
Boston, MA 02114
Summary
- I specialize in liquid biopsy for cardiovascular diseases, with a focus on developing novel biomarkers for the diagnosis and prognosis of these conditions. Additionally, I lead the SEAL-HF study, which investigates RNA profiles in extracellular vesicles to develop new diagnostic tests for heart failure, aiming to enhance early detection and improve patient outcomes.
My research centers on the application of Extracellular Vesicles (EVs) and extracellular RNAs (exRNAs) as non-invasive diagnostic and therapeutic tools. I am dedicated to advancing methods for capturing and analyzing cardiomyocyte-specific EVs from various biofluids, including blood and saliva.
Education & Training
Athens Medical School, National & Kapodistrian University of AthensClass of 2020
Clinical Trials
- Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF) Start of enrollment: 2023 Apr 19
Roles: Contact, Study Director
Publications & Presentations
PubMed
- Cirbp: A Key Regulator in Hypothermic Cardioprotection of Aged Donor Hearts During Transplantation.Danni Meng, Michail Spanos, Junjie Xiao
Journal of Cardiovascular Translational Research. 2024-12-01 - Inhibition of METTL4: Targeting a Methyltransferase that Alleviates Heart Failure by Modulating Excess N6-Methyladenine in Mitochondrial DNA.Jiaqi Wang, Michail Spanos, Yihua Bei
Journal of Cardiovascular Translational Research. 2024-10-01 - A Novel Prediction Model for Post-TAVI MACCE Based on Extracellular Vesicles Concentration Analysis.Shuqin Liu, Michail Spanos, Jing Wang, Junjie Xiao
Journal of Cardiovascular Translational Research. 2024-10-01
Press Mentions
Molecules produced by cells in response to stress may be indicators of various diseasesApril 4th, 2022
Committees
- Editorial Board, Journal of Cardiovascular Translational Research 2022 - Present
Other Languages
- Greek
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