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Office
185 Cambridge st
Boston, MA 02114
Summary
- I specialize in liquid biopsy for cardiovascular diseases, with a focus on developing novel biomarkers for the diagnosis and prognosis of these conditions. Additionally, I lead the SEAL-HF study, which investigates RNA profiles in extracellular vesicles to develop new diagnostic tests for heart failure, aiming to enhance early detection and improve patient outcomes.
My research centers on the application of Extracellular Vesicles (EVs) and extracellular RNAs (exRNAs) as non-invasive diagnostic and therapeutic tools. I am dedicated to advancing methods for capturing and analyzing cardiomyocyte-specific EVs from various biofluids, including blood and saliva.
Education & Training
Athens Medical School, National & Kapodistrian University of AthensClass of 2020
Clinical Trials
- Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF) Start of enrollment: 2023 Apr 19
Roles: Contact, Study Director
Publications & Presentations
PubMed
- Injectable hydrogel with miR-222-engineered extracellular vesicles ameliorates myocardial ischemic reperfusion injury via mechanotransduction.Yongtao Wang, Danni Meng, Xiaohui Shi, Yan Hou, Shihui Zang
Cell Reports. Medicine. 2025-03-18 - Nanomedicines for cardiovascular diseases: Lessons learned and pathways forward.Yi-An Mao, Xiaozhou Shi, Pingyuan Sun, Michail Spanos, Liyun Zhu
Biomaterials. 2025-03-18 - Traditional Chinese Medicine Monomers Are Potential Candidate Drugs for Cancer-Induced Cardiac Cachexia.Zhizheng Li, Xinyi Peng, Xinyi Zhu, Michail Spanos, Lan Wu
Pharmacology. 2025-01-01
Press Mentions
Molecules produced by cells in response to stress may be indicators of various diseasesApril 4th, 2022
Committees
- Editorial Board, Journal of Cardiovascular Translational Research 2022 - Present
Other Languages
- Greek
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