MichaelBYaffeMD

General Surgery • West Roxbury, MA

Trauma Surgery & Surgical Critical Care

David H. Koch Professor, MIT and Beth Israel Deaconess Medical Center

Join to view full profile

Dr. Yaffe is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
Connect with colleagues in the same hospital or clinic.
Read the latest clinical news, personalized to your specialty.

See Dr. Yaffe's full profile

Already have an account?

Office
1 Chesbrough Rd
West Roxbury, MA 02132
Phone+1 617-452-2103

Education & Training

Beth Israel Deaconess Medical CenterFellowship, Surgical Critical Care, 1995 - 1996
Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Surgery, 1991 - 1995
Beth Israel Deaconess Medical CenterResidency, Surgery, 1989 - 1991
Case Western Reserve University School of MedicineClass of 1989

Certifications & Licensure

MA State Medical License 1996 - 2025
OH State Medical License 1992 - 1996
American Board of Surgery Surgery
American Board of Surgery Surgical Critical Care

Publications & Presentations

PubMed

An RNA damage response network mediates the lethality of 5-FU in colorectal cancer.
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng
Cell Reports. Medicine. 2024-10-15
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks.
Bert van de Kooij, Fenna J van der Wal, Magdalena B Rother, Wouter W Wiegant, Pau Creixell
Nature Communications. 2024-08-16
Signal amplification by cyclic extension enables high-sensitivity single-cell mass cytometry.
Xiao-Kang Lun, Kuanwei Sheng, Xueyang Yu, Ching Yeung Lam, Gokul Gowri
Nature Biotechnology. 2024-07-29

Lectures

8th Protein Kinases in Drug Discovery Conference
Global Technology Community (GTC), Boston, Massachusetts - 7/8/2013

Press Mentions

3 Questions: Michael Yaffe on Treating Covid-19 Patients with Acute Respiratory DistressApril 29th, 2020
Repurposing a Drug for Blood Clots: A Stopgap Measure to Treat Respiratory Distress in COVID-19March 30th, 2020
Blood Clot-Dissolving Drug May Treat Critical Covid-19 PatientsMarch 27th, 2020
Join now to see all

Grant Support

DNA Damage NetworksNational Cancer Institute2010–2012
Biopolymers &ProteomicsNational Cancer Institute2010–2012
Project 7National Institute Of General Medical Sciences2008–2011
Protein Kinase Signaling And Cell Cycle ControlNational Institute Of Environmental Health Sciences2007–2011
Cell Growth &Proliferation Gordon Research ConferenceNational Cancer Institute2007–2011
Neutrophil Priming In Trauma And SepsisNational Institute Of General Medical Sciences2000–2011
Core--Biopolymer LaboratoryNational Cancer Institute2007–2009
High-Content Screening For Modifiers Of The DNA Damage ResponseNational Institute Of Neurological Disorders And Stroke2008
2004 Growth Factor Signalling Gordon ConferenceNational Cancer Institute2006–2008
Structure Of The Sigma Isoform Of The Phosphopeptide-Binding Protein 14-3-3National Center For Research Resources2005–2008
DNA Repair SignalingNational Cancer Institute2004–2008
Phosphoserine Dependant Assembly Of Signaling ComplexesNational Institute Of General Medical Sciences2004–2007
Ncrr Shared Instrumentation Grant (SIG) PROGRAM: Structural BiologyNational Center For Research Resources2005
Ncrr Shared Instrumentation Grant (SIG) ProgramNational Center For Research Resources2005
Ncrr (SIG) PROGRAM: Struct Biol: Clp-X ProjectsNational Center For Research Resources2005
Identification Of Molecular Pathways In Cancer BiologyNational Cancer Institute2004–2005
High-Throughput Assay Design:Polo Kinase Inhibitors(Rmi)National Institute Of Neurological Disorders And Stroke2004
Sigma Isoform Of Phosphopeptide-Binding Protein 14-3-3National Center For Research Resources2004
Phosphoserine Dependent Assembly Of Signaling ComplexesNational Institute Of General Medical Sciences2000–2003
Phosphoserine Dependent Assembly Of Signaling ComplexesNational Institute Of General Medical Sciences2000
Neutrophil Priming In Trauma And SepsisNational Institute Of General Medical Sciences1999–2000
Heat Shock Protein HSP-90 Following InjuryNational Heart, Lung, And Blood Institute1997–1999
Heat Shock Protein HSP90 Following InjuryNational Heart, Lung, And Blood Institute1998