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Office
Nhlbi Nih
Bld 10-Crc, Rm 53150, 10 Center Drive
Bethesda, MD 20892Phone+1 301-402-9259Fax+1 301-402-0888
Education & Training
- Washington University/B-JH/SLCH ConsortiumFellowship, Cardiovascular Disease, 1994 - 1998
- MedStar Health/Georgetown University HospitalResidency, Internal Medicine, 1991 - 1994
- University of the WitwatersrandClass of 1988
Certifications & Licensure
- MD State Medical License 1992 - 2025
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2009
Clinical Trials
- Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System Start of enrollment: 2010 Jul 21
- Mutations Associated With Parkinson s Disease Start of enrollment: 2012 Feb 27
- Effect of Fasting and Refeeding on T-cell Fate Start of enrollment: 2016 Apr 18
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Publications & Presentations
PubMed
- 53 citationsEmerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heartMichael N. Sack
American Journal of Physiology. Heart and Circulatory Physiology. 2011-12-01 - 85 citationsUnlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Wo...Rong Tian, Wilson S. Colucci, Zoltan Arany, Markus Bachschmid, Scott W. Ballinger
Circulation. 2019-10-01 - 49 citationsThe complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation.Christopher L. Riley, Christine K. Dao, M. Alexander Kenaston, Luigina Muto, Shohei Kohno
The Journal of Physiology. 2016-12-15
Journal Articles
- Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4+ T Cell ActivationMichael Sack, MD, The Journal of Immunology
- A Pilot Study to Investigate the Immune-Modulatory Effects of Fasting in Steroid-Naive Mild AsthmaticsMichael N Sack, Stewart J Levine, The Journal of Immunology
- Second Signals Rescue B Cells from Activation-Induced Mitochondrial Dysfunction and DeathMichael N Sack, Susan K Pierce, Nature
Press Mentions
- ChromaDex Clinical Trial Shows Anti-Inflammatory Effects of NR SupplementJanuary 28th, 2022
- New Clinical Data Is Promising for NR Supplementation and Anti-Inflammatory EffectsJanuary 25th, 2022
- Reducing Obesity-Related InflammationNovember 16th, 2015
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Grant Support
- Metabolic Regulation In The Pathophysiology Of DiabetesNational Heart, Lung, And Blood Institute2010–2011
- Acetylation In The Control Of Mitochondrial HomeostasisNational Heart, Lung, And Blood Institute2010–2011
- Mitochondrial Biology In Cardiovascular DiseaseNational Heart, Lung, And Blood Institute2009–2011
- Mitochondrial Biology In DiabetesNational Heart, Lung, And Blood Institute2009
- Mitochondrial Biology In DiabetesNational Heart, Lung, And Blood Institute2007–2008
- Mitochondrial Biology In Cardiovascular DiseaseNational Heart, Lung, And Blood Institute2005–2008
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