MichaelS.RafiiMDPhD

Neurology • San Diego, CA

Associate Professor of Neurology, Keck School of Medicine of USC

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Office
4510 Executive Dr
San Diego, CA 92121
Phone+1 858-657-8540

Fax+1 858-657-8557

Education & Training

Johns Hopkins UniversityResidency, Neurology, 2003 - 2006
Johns Hopkins UniversityInternship, Internal Medicine, 2002 - 2003
The Warren Alpert Medical School of Brown UniversityClass of 2002

Certifications & Licensure

CA State Medical License 2006 - 2026
American Board of Psychiatry and Neurology Neurology

Clinical Trials

AC-1204 26-Week Long Term Efficacy Response Trial With Optional Open-label Ext Start of enrollment: 2013 Mar 01
Completed
Phase 2, Phase 3
Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo Start of enrollment: 2013 Jul 01
Terminated
Phase 3
Down Syndrome Biomarker Initiative (DSBI) Start of enrollment: 2013 Jun 01
Completed
Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome Start of enrollment: 2016 Mar 01
Completed
Phase 1
Trial-Ready Cohort-Down Syndrome (TRC-DS) Start of enrollment: 2021 Jun 07
Recruiting
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Publications & Presentations

PubMed

Clinical and neuropathological analysis of Down syndrome over 7 decades of life.
Sonal Sukreet, Vanessa S Goodwill, Jennifer Ngolab, Ha Y Kim, Solana Leisher
Journal of Neuropathology and Experimental Neurology. 2025-02-01
Artificial intelligence-enabled safety monitoring in Alzheimer's disease clinical trials.
Gustavo A Jimenez-Maggiora, Michael C Donohue, Michael S Rafii, Rema Raman, Paul S Aisen
The Journal of Prevention of Alzheimer's Disease. 2025-01-01
Diagnostic abnormalities, disease severity and immunotherapy responsiveness in individuals with Down syndrome regression disorder.
Jonathan D Santoro, Saba Jafarpour, Laura Keehan, Mellad M Khoshnood, Lilia Kazerooni
Scientific Reports. 2024-12-28

Journal Articles

Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease
Reisa Sperling, Michael S Rafii, Gary Romano, JAMA Neurology

Press Mentions

Alzheimer's Meds Are Here. But for the down Syndrome Community, It's Still the 1980sMarch 1st, 2023
Top Dementia Scientists Present Key Findings, InitiativesNovember 28th, 2022
It’s Not a Normal Sign of Aging: Mild Cognitive Impairment Takes TollApril 19th, 2022
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