MichaelCMiloneMD

Blood Banking & Transfusion Medicine, Anatomic Pathology, Clinical Pathology

Assistant Professor, Pathology & Laboratory Medicine, Perelman School of Medicine

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University of Pennsylvania Health SystemFellowship, Blood Banking/Transfusion Medicine, 2002 - 2003
University of Pennsylvania Health SystemResidency, Pathology-Anatomic and Clinical, 2000 - 2002
University of Pennsylvania Health SystemInternship, Internal Medicine, 1999 - 2000
Rutgers New Jersey Medical SchoolClass of 1999

PubMed

2503 citations
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.
Stephan A. Grupp, Michael Kalos, David M. Barrett, Richard Aplenc, David L. Porter
The New England Journal of Medicine. 2013-04-17
191 citations
Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy
Vijay Bhoj, Dimitrios Arhontoulis, Gerald Wertheim, James Capobianchi, Colleen Callahan
Blood. 2016-07-21
329 citations
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.
Omkar U Kawalekar, Roddy S O'Connor, Joseph A Fraietta, Lili Guo, Shannon E McGettigan
Immunity. 2016-02-16

Journal Articles

Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-Exposure SARS-CoV-2 Prophylaxis Among Health Care Workers
Matthew C Hyman, Ian Frank, Scott E Hensley, Saar Gill, Dan T Vogl, Ivan Maillard, Daria V Babushok, Alexander C Huang, Sunita D Nasta, Jennifer C Walsh, Michael C Mil..., JAMA Internal Medicine
CAR T Cell Immunotherapy for Human Cancer
Carl H June, Michael C Milone, Science Magazine
High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Stephan A Grupp, Zissimos Mourelatos, Michael C Milone, David M Barrett, Sarah A Richman, Clinical Cancer Research

Lectures

Predictors of T Cell Expansion and Clinical Responses Following B-Cell Maturation Antigen-Specific Chimeric Antigen Receptor T Cell Therapy (CART-BCMA) for Relapsed/Re...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
PD-1 Inhibitor Combinations As Salvage Therapy for Relapsed/Refractory Multiple Myeloma (MM) Patients Progressing after Bcma-Directed CAR T Cells
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Clinical Predictors of T Cell Fitness for CAR T Cell Manufacturing and Efficacy in Multiple Myeloma
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Optimized FVIII-Domain-Based Chimeric Antigen Receptors to Specifically Target FVIII Inhibitor-Producing B Cells in Hemophilia a
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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Penn Medicine Breakthrough Immunotherapy Technique Could Reduce Cost of Cancer TreatmentApril 12th, 2022
Research Roundup: Scientists May Have Solved CAR-T Turnaround ChallengeApril 1st, 2022
FDA Approves Personalized Cellular Therapy for Advanced Leukemia Developed by University of Pennsylvania and Children’s Hospital of PhiladelphiaAugust 30th, 2017
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