MichaelMiksaMDPhD

PubMed

• 1513 citations
  Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.
  Chrysanthy Ikonomidou, Friederike Bosch, Michael Miksa, Petra Bittigau, Jessica Vöckler
  Science. 1999-01-01
• 218 citations
  A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester
  Michael Miksa, Hidefumi Komura, Rongqian Wu, Kavin G. Shah, Ping Wang
  Journal of Immunological Methods. 2009-03-15
• 72 citations
  Pivotal Role of the α2A-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis
  Michael Miksa, Padmalaya Das, Mian Zhou, Rongqian Wu, Weifeng Dong
  Plos One. 2009-05-11

Journal Articles

• Control of serum glucose concentration in critical illness  
  Kandil SB, Miksa M, Faustino EV, Curr Opin Pediatr, 1/1/2013
• Milk fat globule epidermal growth factor 8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion  
  Cui T, Miksa M, Wu R, Komura H, Zhou M, Dong W, Wang Z, Higuchi S, Chaung W, Blau SA, Marini CP, Ravikumar TS, Wang P, Am J Respir Crit Care Med, 1/1/2010
• A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester  
  Miksa M, Komura H, Wu R, Shah KG, Wang P, J Immunol Methods, 3/1/2009
• Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII  
  Miksa M, Wu R, Dong W, Komura H, Amin D, Ji Y, Wang Z, Wang H, Ravikumar TS, Tracey KJ, Wang P, J Immunol, 1/1/2009
• Ghrelin hyporesponsiveness contributes to age-related hyperinflammation in septic shock  
  Wu R, Zhou M, Dong W, Ji Y, Miksa M, Marini CP, Ravikumar TS, Wang P, Ann Surg, 1/1/2009
• Pivotal role of the alpha(2A)-adrenoceptor in producing inflammation and organ injury in a rat model of sepsis  
  Miksa M, Das P, Zhou M, Wu R, Dong W, Ji Y, Goyert SM, Ravikumar TS, Wang P, PLoS One, 1/1/2009
• VX-166: a novel potent small molecule caspase inhibitor as a potential therapy for sepsis  
  Weber P, Wang P, Maddens S, Wang PSh, Wu R, Miksa M, Dong W, Mortimore M, Golec JM, Charlton P, Crit Care, 1/1/2009
• Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response  
  Miksa M, Amin D, Wu R, Jacob A, Zhou M, Dong W, Yang WL, Ravikumar TS, Wang P, Int J Mol Med, 1/1/2008
• Downregulation of protein disulfide isomerase in sepsis and its role in tumor necrosis factor-alpha release  
  Zhou M, Jacob A, Ho N, Miksa M, Wu R, Maitra SR, Wang P, Crit Care, 1/1/2008
• Milk fat globule epidermal growth factor-factor VIII is down-regulated in sepsis via the lipopolysaccharide-CD14 pathway  
  Komura H, Miksa M, Wu R, Goyert SM, Wang P, J Immunol, 1/1/2008
• Ghrelin inhibits sympathetic nervous activity in sepsis  
  Wu R., Zhou M., Das P., Dong W., Ji Y., Yang D., Miksa M., Zhang F., Ravikumar T., Wang P, Am J Physiol Endoc M, 1/1/2007
• Vasoactive hormone adrenomedullin and its binding protein: anti-inflammatory effects by upregulating PPAR-gamma  
  Miksa, M., Wu R., Cui X., Dong W., Das P., Simms H.H., Ravikumar T.S., Wang, P, J Immunol, 1/1/2007
• Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages  
  Miksa, M., D. Amin, R. Wu, T. S. Ravikumar, and P. Wang, Mol Med, 1/1/2007
• Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis  
  Miksa, M., R. Wu, W. Dong, P. Das, D. Yang, and P. Wang, Shock, 1/1/2006
• Sympathetic excitotoxicity in sepsis: pro-inflammatory priming of macrophages by norepinephrine  
  Miksa, M., R. Wu, M. Zhou, and P. Wang, Front Biosci, 1/1/2005
• Gut-brain interaction in sepsis. E-Letter response to M Badman, J Flier: The Gut and Energy Balance: Visceral Allies in the Obesity Wars  
  Miksa, M, Science, 1/1/2005
• Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain  
  Ikonomidou, C., F. Bosch, M. Miksa, P. Bittigau, J. Vockler, K. Dikranian, T. I. Tenkova, V. Stefovska, L. Turski, and J. W. Olney, Science, 1/1/1999
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Abstracts/Posters

• Fractalkine Induces MFG-E8 and Anti-Inflammatory IL-10 in Sepsis
  M. Miksa, et al., Crit Care Med, 35th Critical Care Congress, 2/6/2008
• Erhohte Sterblichkeit von Mausen mit Lactadherinmangel in einer Sepsis: Rolle Verminderter Phagozytose Apoptotischer Zellen
  Miksa, M., D. Dong, R. Wu, T. S. Ravikumar, and P. Wang, Z Geburtshilfe Neonatol, 1/1/2007
• Impaired apoptotic cell clearance in MFG-E8-deficient mice leads to increased mortality in sepsis
  Miksa, M., D. Dong, R. Wu, Y. Ji, T. S. Ravikumar, and P. Wang, Shock, 1/1/2007
• Downregulation of milk fat globule EGF-factor VIII in sepsis is CD14-dependent
  Komura, H., M. Miksa, R. Wu, S. Goyert, and P. Wang, Shock, 1/1/2007
• Hyporesponsiveness to ghrelin contributes to aging-related hyperinflammatory state in septic shock
  Wu, R., M. Zhou, W. Dong, Y. Ji, M. Miksa, C. P. Marini, T. S. Ravikumar, and P. Wang, Shock, 1/1/2007
• Immature Dendritic Cell Derived Exosomes as Gatekeepers in Sepsis
  M. Miksa, et al., Crit Care Med, 35th Critical Care Congress, 1/6/2006
• Fractalkine increases apoptotic cell clearance by upregulation MFG-E8 in macrophages
  Miksa, M., D. Amin, R. Wu, T. S. Ravikumar, and P. Wang, Shock, 1/1/2006
• Downregulation of protein disulfide isomerase (PDI) in sepsis and its role in proinflammatory cytokine release
  Zhou, M., N. Ho, M. Miksa, R. Wu, Y. Cui, and P. Wang, Shock, 1/1/2006
• VX-166, a novel potent small molecule caspase inhibitor, as a promising new treatment for sepsis
  Weber, P., P. Wang, R. Wu, M. Miksa, W. Dong, G. Ku, D. Dawson, K. Miller, and P. Charlton, Critical Care, 1/1/2006
• Ghrelin inhibits sympathetic nervous activity in sepsis
  Wu, R., M. Zhou, P. Das, W. Dong, Y. Ji, D. Yang, M. Miksa, T. S. Ravikumar, and P. Wang, Shock, 1/1/2006
• Immature dendritic cell (DC)-derived exosomes as gatekeepers in sepsis
  Miksa, M., R. Wu, W. Dong, Y. Ji, T. S. Ravikumar, and P. Wang, Crit Care Med, 12/1/2005
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Lectures

• Proposal of a retrospective study re: “Safety of High-Flow Nasal Cannula Use vs. Non-Invasive Ventilation in infants with Bronchiolitis 
  10/1/2013
• Acute Management in the ER 
  Children's Hospital Boston Satellite Pediatric ER at South Shore Hospital, Weymouth, MA - 1/1/2012
• Case Based Learning for MS2 
  SUNY Downstate, Brooklyn, NY - 1/1/2010
• Annual Scientific Cushing Lectures 
  North Shore-LIJ Medical Center, Manhasset, NY - 1/1/2008
• Hyporesponsiveness to ghrelin contributes to aging-related hyperinflammatory state in septic shock 
  Baltimore, MD - 6/9/2007
• Downregulation of milk fat globule EGF-factor VIII in sepsis is CD14-dependent 
  Baltimore, MD - 6/9/2007
• Impaired apoptotic cell clearance in MFG-E8-deficient mice leads to increased mortality in sepsis 
  Baltimore, MD - 6/9/2007
• Downregulation of Protein Disulfide Isomerase in Sepsis and Its Role in Proinflammatory Cytokine Release 
  Denver, CO - 6/2/2006
• Ghrelin Inhibits Sympathetic Nervous Activity in Sepsis 
  Denver, CO - 6/2/2006
• Fractalkine Induces Apoptotic Cell Clearance By Upregulating MFG-E8 In Macrophages 
  1/1/2006
• A Novel Approach to Inhibit Inflammatory Responses in Sepsis: Modulation of the Sympathetic Nervous System 
  Marco Island, FL - 6/4/2005
• Dendritic Cell-Derived Exosomes Expressing MFG-E8 Attenuate Proinflammatory Responses in Sepsis by Promoting Apoptotic Cell Clearance 
  Nashville, TN - 2/9/2005
• Anti-Inflammatory Effects of Andrenomedullin (AM) and AM Binding Protein-1: an ERK-1/2 MAP Kinase-dependent Pathway 
  Nashville, TN - 2/9/2005
• Anti-Inflammatory Effects of AM and AMBP1 are mediated by PPAR-gamma through the cAMP-Dependent Pathway 
  Halifax, Nova Scotia - 6/5/2004
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Other

• N-Methyl-D-Aspartat-Antagonists induce apoptotic Cell Death in Neonatal Rat Brains 
  Miksa, M
  Medical Faculty Charite, Department of Neuropediatrics . Humboldt-University, Berlin - 1/1/2004