Dr. Mendelsohn is on Doximity
As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Office
New England Medical Ctre
750 Washington Street
Boston, MA 02111Phone+1 617-636-9370
Summary
- Cardiovascular physician-scientist, research leader and business executive with broad experience in healthcare (cardiovascular and internal medicine, basic and clinical sciences, executive management). Founder and Executive Chairman of Cardurion Pharmaceuticals, a cardiovascular biotechnology company. Dr. Mendelsohn also serves currently as senior advisor and consultant to the head of R&D at Takeda Pharmaceuticals and as a Board Director of Foghorn Therapeutics and Broadview Ventures. From 2013-2017, Dr. Mendelsohn served as a venture partner at SV Health Investors.
From 2010-2013, Dr. Mendelsohn served as SVP and Global Head of Cardiovascular Diseases, Merck & Co. Prior to Merck, Dr. Mendelsohn worked for 25 years as an academic cardiovascular physician-scientist in Boston. Dr. Mendelsohn received an undergraduate degree in Chemistry and English from Amherst College and his MD from Harvard Medical School (HMS) in 1982. From 1988-1993, he was an assistant professor of medicine on the faculty of HMS, a member of the BWH Cardiology Division and ran an independent, NIH-funded basic science laboratory focused on molecular cardiovascular biology. From 1993-2010, he moved to Tufts Medical Center, where served as the first executive director of the Molecular Cardiology Research Institute, In 2008, Dr. Mendelsohn was named Chief Scientific Officer at Tufts. In 2010, Dr. Mendelsohn was appointed senior vice president and global head of cardiovascular research at Merck Research Laboratories (MRL). He founded Cardurion Pharmaceuticals in 2017.
Education & Training
- Brigham and Women's HospitalFellowship, Cardiovascular Disease, 1985 - 1987
- Brigham and Women's HospitalResidency, Internal Medicine, 1982 - 1985
- Harvard Medical SchoolClass of 1982
Certifications & Licensure
- MA State Medical License 1988 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
Publications & Presentations
PubMed
- 9 citationsThe mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure.Guangshuo Zhu, Kazutaka Ueda, Masaki Hashimoto, Manling Zhang, Masayuki Sasaki
FEBS Letters. 2021-11-14 - 15 citationsCRD-733, a Novel PDE9 (Phosphodiesterase 9) Inhibitor, Reverses Pressure Overload-Induced Heart Failure.Daniel A. Richards, Mark Aronovitz, Peiwen Liu, Gregory L. Martin, Kelly Tam
Circulation. Heart Failure. 2021-01-01 - 58 citationsPDE5 inhibitor efficacy is estrogen dependent in female heart diseaseHideyuki Sasaki, Takahiro Nagayama, Robert M. Blanton, Kinya Seo, Manling Zhang
The Journal of Clinical Investigation. 2014-06-02
Press Mentions
- Cardurion Pharmaceuticals Announces Investment from Polaris Partners and Appoints Amy Schulman to Board of DirectorsNovember 20th, 2019
- Ironwood Pharmaceuticals Announces Board of Directors for Ironwood and Cyclerion, Effective Following SeparationJanuary 24th, 2019
Grant Support
- Vascular Surgery - Estrogen And The Injury ResponseNational Heart, Lung, And Blood Institute2003–2009
- Nitric Oxide Signaling Mechanisms In Vascular CellsNational Heart, Lung, And Blood Institute1996–2009
- Molecular Mechanisms Of Vascular RelaxationNational Heart, Lung, And Blood Institute2004–2008
- Training Program In Cardiovascular ResearchNational Heart, Lung, And Blood Institute2003–2007
- Molecular Biology Of The VasculatureNational Heart, Lung, And Blood Institute2005
- Cellular Fluorescence-Contractility Imaging System: Cardiovascular ResearchNational Center For Research Resources2005
- Cellular Fluorescence-Contractility Imaging SystemNational Center For Research Resources2005
- Core A-- Administration CoreNational Heart, Lung, And Blood Institute2004
- Specialized Center Of Research In Ischemic Heart DiseaseNational Heart, Lung, And Blood Institute2000–2004
- Estrogen Receptor Regulation Of NO SynthasesNational Heart, Lung, And Blood Institute2000–2004
- Core A-- AdministrativeNational Heart, Lung, And Blood Institute2003
- Vascular Estrogen Receptors--Molecular MechanismsNational Heart, Lung, And Blood Institute1998–2001
- Vascular Surgery--Estrogen And The Injury ResponseNational Heart, Lung, And Blood Institute1997–1999
- Endothelial-Derived Relaxing Factor &Platelet FunctionNational Heart, Lung, And Blood Institute1992–1993
- Endothelial-Derived Relaxing Factor &Platelet FunctionNational Heart, Lung, And Blood Institute1989–1992
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence: