MichaelWilliamLawlorMD

PubMed

• High mobility group box 1 (HMGB1) is a potential disease biomarker in cell and mouse models of Duchenne muscular dystrophy.
  Rebecca A Slick, Jessica Sutton, Margaret Haberman, Benjamin S O'Brien, Jennifer A Tinklenberg
  Biology Open. 2024-09-15
• Injectable and Dynamically Crosslinked Zwitterionic Hydrogels for Anti-Fouling and Tissue Regeneration Applications.
  Zhicheng Pan, Jonathan Dorogin, Andrew Lofts, Gurpreet Randhawa, Fei Xu
  Advanced Healthcare Materials. 2024-07-01
• 1 citations
  Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects.
  Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani
  Acta Neuropathologica. 2024-04-18

Journal Articles

• Whole thorax irradiation induces hypoxic respiratory failure, pleural effusions, and congestive heart failure  
  Medhora M, Gao F, Glisch C, Narayanan J, Sharma A, Harmann LM, Lawlor MW, Snyder LA, Fish BL, Down JD, Moulder JE, Strande JL, Jacobs ER, Journal of Radiation Research, 1/3/2014
• Polydopamine coatings enhance biointegration of a model polymeric implant  
  Jeong KJ, Wang LQ, Stefanescu CF, Lawlor MW, Polat J, Dolhman CH, Langer RS, Kohane DS, Soft Matter, 1/1/2011

Books/Book Chapters

• ISN Book on Muscle Disease: Pathology and Genetics 
  Chapter: "Thin filament proteins (nemaline and related myopathies)" 
  Page 145 - 151Lawlor MW, Beggs AHWiley-Blackwell, Hoboken2013
• Rapid Review for the USMLE Step 2 
  Lawlor MWMosby, Philadelphia2007
• Zebra Mussels and Aquatic Nuisance Species 
  Chapter: "The effect of high voltage electrostatic fields on zebra mussels" 
  Page 429 - 438Shana ZA, Maki JS, Zanoni AE, Benes SJ, Mercier CJ, Lawlor MWEditors: FM D'Itri.Ann Arbor Press, Ann Arbor1997

Abstracts/Posters

• Treatment with ActRIIB-mFc Improves Lifespan, Behavior, and Pathology in the Acta1 H40Y Murine Model of Nemaline Myopathy.
  Lawlor MW et al, American Association of Neuropathologists Meeting; New Directions in Biology and Disease of Skeletal Muscle Conference, 1/29/2014
• Gene replacement therapy improves muscle function and pathology in murine and canine models of X-linked myotubular myopathy.
  Lawlor MW et al, American Association of Neuropathologists Meeting, 1/20/2013
• Integration of common data elements into muscle biopsy reporting.
  Dastgir J, Rutkowski A, Alvarez R, Cossette S, Yan K, Hoffmann R, Hayashi Y, Goebel HH, Bonnemann C, Lawlor MW, American Association of Neuropathologists Meeting; Canadian Association of Neuropathologists Meeting, 1/16/2013
• Integration of common data elements into muscle biopsy reporting.
  Dastgir J, Rutkowski A, Alvarez R, Cossette S, Yan K, Hoffmann R, Hayashi Y, Goebel HH, Bonnemann C, Lawlor MW, Muscular Dystrophy Association National Scientific Conference; World Muscle Society Conference, 1/1/2013
• Satellite cell depletion and dysfunction correlates with disease progression in severe murine myotubularin deficiency.
  Lawlor MW, Alexander MS, Viola MG, Meng H, Gupta V, Motohashi N, Manfready RA, Hsu CP, Huang P, Joubert R, Buj Bello A, Kunkel LM, Beggs AH, Gussoni E, American Association of Neuropathologists Meeting; New Directions in Biology and Disease of Skeletal Muscle Meeting, 1/21/2012
• Ultrastructural pathology and functional deficits can be reversed following enzyme replacement in myotubularin deficient mice.
  Lawlor MW, Armstrong D, Viola MG, Meng H, Buj-Bello A, Hsu CP, Pierson CR, Childers MK, Grange RW, Widrick JJ, Beggs AH, American Association of Neuropathologists Meeting; New Directions in Biology and Disease of Skeletal Muscle Meeting, 1/21/2012
• Responses to ActRIIB-mFc treatment are specific to individual muscles in the Mtm1p.R69C model of myotubularin deficiency.
  Lawlor MW, Viola MG, Meng H, Edelstein RV, Pierson CR, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH, New Directions in Biology and Disease of Skeletal Muscle Meeting, 1/17/2012
• Distribution and extent of weakness is dependent on fiber type and mutation in murine models of myotubularin deficiency.
  Lawlor MW, Viola MG, Widrick JJ, Grange RW, Buj-Bello A, Pierson CR, Beggs AH, American Association of Neuropathologists Meeting, Seattle, WA, 1/23/2011
• Responses to treatment are dependent of fiber type, muscle, and mutation in murine models of myotubularin deficiency.
  Lawlor MW, Viola MG, Edelstein RV, Pierson CR, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH, American Association of Neuropathologists Meeting, Seattle, WA, 1/23/2011
• Responses to treatment are dependent on fiber type and mutation in murine models of myotubularin deficiency.
  Lawlor MW, Viola MG, Edelstein RV, Pierson CR, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH, 2011 Muscular Dystrophy Association National Scientific Conference, Las Vegas, NV, 1/13/2011
• Impaired contractile properties in myotubularin deficient mice and dogs.
  Lawlor MW, Grange RW, Edelstein RV, Shelton GD, Pierson CR, Buj Bello A, Tegeler C, Childers MK, Beggs AH, 2010 New Directions in Biology and Disease of Skeletal Muscle Meeting, Ottawa, Canada, 1/5/2010
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Lectures

• "Treatment with ActRIIB-mFc Improves Lifespan, Behavior, and Pathology in the Acta1 H40Y Murine Model of Nemaline Myopathy" 
  1/2/2014
• "Congenital muscle disease consortium international workshop" (organizer and speaker) 
  Washington, DC - 1/21/2013
• "Diagnostic and genetic considerations in the congenital myopathies." 
  1/19/2013
• "Current advances in nemaline myopathy research" 
  Stanford University - 1/6/2013
• "Emerging treatments for X-linked myotubular myopathy." 
  University of Kentucky, Lexington - 1/1/2013
• "Infrastructure established in the Congenital Muscle Disease Tissue Repository and opportunities for tissue use in biomarker discovery efforts" 
  Pacific Grove, CA - 1/1/2013
• "Pumping up the myotubularin-deficient mouse: A pre-clinical trial for congenital myopathy." 
  University of Pittsburgh Medical Center - 1/1/2009
• "Taking the USMLE Step 2 Exam." 
  Loyola University Chicago - 1/1/2007
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