MichaelG.HughesJr.MD

PubMed

• 2 citations
  Nutritional Assessment in Patients after Gastric Electrical Stimulation (GES).
  Tanureet Kochar, Wenjing Cai, John J Guardiola, Prateek Mathur, Hamza Hassan
  Journal of Clinical Gastroenterology. 2024-02-01
• 3 citations
  Baseline predictive factors for foregut and hindgut response to long-term gastric electrical stimulation using augmented energy.
  Mohamed Elmasry, Hamza Hassan, Prateek Mathur, Abigail Stocker, Hadi Atassi
  Neurogastroenterology and Motility. 2021-10-26
• 14 citations
  Pathophysiology of Gastroparesis Syndromes Includes Anatomic and Physiologic Abnormalities
  Thomas L. Abell, Archana Kedar, Abigail Stocker, Karen Beatty, Lindsay McElmurray
  Digestive Diseases and Sciences. 2021-04-01

Journal Articles

• Improved Recovery of Human Islets from Young Donor Pancreases Utilizing Increased Protease Dose to Collagenase for Digesting Peri‐Islet Extracellular Matrix  
  Michael Hughes Jr., MD, American journal of transplantation
• The impact of recipient obesity on outcomes after renal transplantation  
  Cannon RM, Jones CM, Hughes MG, Eng M, Marvin MR, Annals of Surgery, 1/1/2013
• A review of the United States experience with combined heart-liver transplantation  
  Cannon RM, Hughes MG, Jones, CM, Eng, M, Marvin MR, Transplant International, 1/1/2012
• BK virus in renal transplantation  
  Cannon R, Ouseph R, Jones C, Hughes M, Eng M, Marvin M, Current Opinion in Organ Transplantation, 1/1/2011
• Long-term outcome in 42 pediatric liver transplant patients with alpha 1-antitrypsin deficiency: A single-center experience  
  Hughes MG, Khan KM. Gruessner AC, Sharp H, Hill M, Jie T, Kandaswamy R, Humar A, Payne WD, Gruessner RW, Clinical Transplantation, 1/1/2011
• Can preemptive cytomegalovirus monitoring be as effective as universal prophylaxis when implemented as the standard of care in patients at moderate risk?  
  McGillicuddy JW, Weimert NA, Taber DJ, Turner A, Mitchell LA, Wray DW, Egidi MF, Kuppachi S, Hughes MG, Baliga PK, Chavin KD, Transplantation, 1/1/2010
• Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity  
  Zhang Y, Liu Y, Moxley KM, Golden-Mason L, Hughes MG, Liu T, Heemskerk MHM, Rosen HR, Nichimura MI, PLoS pathogens, 1/1/2010
• Human liver transplantation as a model to study HCV pathogenesis  
  Hughes MG, Rosen HR, Liver Transplantation, 1/1/2009
• Graft weight/recipient weight ratio: How well does it predict outcome after partial liver transplants?  
  Hill MJ, Hughes MG, Jie T, Cohen M, Lake J, Payne WD, Humar A, Liver Transplantation, 1/1/2009
• Does body mass index affect infection-related outcomes in the intensive care unit?  
  Smith RL, Chong TW, Hedrick TL, Hughes MG, Evans HL, McElearney ST, Pruett Tl, Sawyer RG, Surg Infect (Larchmt), 1/1/2007
• Cost of gram-negative resistance  
  Evans HL, Lefrak SN, Lyman J, Smith RL, Chong TW, McElearney ST, Schulman AR, Hughes MG, Raymond DP, Pruett TL, Sawyer RG, Crit Care Med, 1/1/2007
• General surgery morning report: A competency-based conference that enhances patient care and resident education  
  Stiles BM, Reece TB, Hedrick TL, Garwood RA, Hughes MG, Dubose JJ, Adams RB, Schirmer BD, Sanfey HA, Sawyer RG, Curr Surg, 1/1/2006
• Primary human hepatocytes in spheroid formation to study hepatitis C infection  
  Chong TW, Smith RL, Hughes MG, Camden J, Rudy CK, Evans HL, Sawyer RG, Pruett TL, J Surg Res, 1/1/2006
• Comparison of fungal and nonfungal infections in a broad-based surgical patient population  
  Hughes MG, Chong TW, Smith RL, Evans HL, Pruett TL, Sawyer RG, Surg Infect (Larchmt), 1/1/2005
• Nature of gram-negative rod antibiotic resistance during antibiotic rotation  
  Evans HL, Milburn ML, Hughes MG, Smith RL, Chong TW, Raymond DP, Pelletier SJ, Pruett TL, Sawyer RG, Surg Infect (Larchmt), 1/1/2005
• HCV infection of the transplanted liver: Changing CD81 and HVR1 variants immediately after liver transplantation  
  Hughes MG, Chong TW, Smith RL, Evans HL, Iezzoni JC, Sawyer RG, Rudy CK, Pruett TL, Am J Transplant, 1/1/2005
• Impact of immunomodulatory oligodeoxynucleotides on cytokine production in the lipopolysaccharide-stimulated human whole blood model  
  Smith RL, Chong TW, Hughes MG, Hedrick TL, Evans HL, MacElerney ST, Salwaacher AR, Raymond DP, Du K, Rudy CK, Pruett TL, Sawyer RG, Surgery, 1/1/2004
• E2 quasispecies specificity of hepatitis C versus association with allografts immediately after liver transplantation  
  Hughes MG, Rudy CK, Chong TW, Smith RL, Evans HL, Iezzoni JC, Sawyer RG, Pruett TL, Liver Transplantation, 1/1/2004
• Effect of an ICU rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit ward  
  Hughes MG, Raymond DP, Evans HL, Smith RL, Chong TW, Pruett TL, Sawyer RG, Crit Care Med, 1/1/2004
• Does prior transfusion worsen outcomes from infection in surgical patients?  
  Hughes MG, Evans HL, Lightfoot L, Chong TW, Smith RL, Raymond DP, Pelletier SJ, Claridge JA, Pruett TL, Sawyer RG, Surgical Infections, 1/1/2003
• Contact isolation in surgical patients: A barrier to care?  
  Evans HL, Shaffer MM, Hughes MG, Smith RL, Chong TW, Raymond DP, Volles DF, Pelletier SJ, Pruett TL, Sawyer RG, Surgery, 1/1/2003
• Fungal infections in trauma and burn patients  
  Hughes MG, Sawyer RS, Current Treatment Options in Infectious Diseases, 1/1/2001
• Hyaluronan enhances contraction of collagen by smooth muscle cells and adventitial fibroblasts Role of CD44 and implications for constrictive remodeling  
  Travis JA, Hughes MG, Wong JM, Wagner WD, Geary RL, Circ Res, 1/1/2001
• Hyaluronan is induced by arterial injury and promotes CD44-mediated smooth muscle cell contraction of collagen gels: Potential role in restenosis  
  Wong JM, Hughes MG, Wagner WD, Geary RL, Cardiovasc Surg, 1/1/2000
• Hyaluronan is induced by arterial injury and promotes collagen gel contraction by smooth muscle cells (SMC) and adventitial fibroblasts: Potential role in post-angiopl...  
  Hughes MG, Wong JA, Gotow L. Wagner WD, Geary RL, J Vasc Surg, 1/1/1999
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Books/Book Chapters

• Contemporary Pancreas Transplantation 
  Chapter: Islet cell transplantation in organ and tissue transplantation. 
  Balamurugan AN, Loganathan G, Tweed B, Hughes MG, Williams SKEditors: Lim JW.Springer International Publishing2016

Abstracts/Posters

• Rate of hepatitis C viral clearance by human livers in human patients: Liver transplantation modeling primary infection and implications for studying entry inhibition.
  Hughes MG Jr, Tucker WW, Reddy S, Brier ME, Koch D, McClain CJ, et al, PLOS One, 1/1/2017
• Mechanisms of Angiogenesis Process after Pancreatic Islet Cell Transplantation: Role of Intra-islet Endothelial Cells.
  Narayanan S, Loganathan G, Dhanasekaran M, Hughes MJ, Williams SK, et al, J Transplant Technol Res, 1/1/2017
• Technical Modifications to Improve Islet Yield from Chronic Pancreatitis Pancreas (CPP) for Islet Auto-Transplantation (IAT).
  Dhanasekaran M, Loganathan G, Narayanan S, Tucker W, Patel A, et al, J Clin Exp Transplant, 1/1/2017
• (Tul427) Neuromuscular evaluation of drug and device refractory patients with the symptoms of gastroparesis reveals a variety of adnormalities.
  Abell TL, Soota K, Patel C, McElmurray L, Stocker AM, Hughes MG, Kedar A, Vendanarayanan V, Rashed H, Gastroenterology, 1/1/2015
• Multicenter experience with Simeprevir/Sofosbuvir combination therapy for recurrent Hepatitis C virus infection in liver transplant recipients from all centers within ...
  Crittenden N, Buchanan L, Rosenau J, Marsano L, Goshko B, McClain C, Barve A, Marvin M, Jones C, Davis EG, Hughes M, Cave M, AASLD Conference, 1/1/2015
• (Sul851) Clinical correspondence of S100 levels on full thickness gastric biopsy.
  Patel C, Abell TL, Soota K, Yang X, Faig MM, Beatty K, Miller E, Kedar A, Hughes MG, McElmurray L, Stocker AM, Kennedy WR, Wendelschafer-Crabb G, Gastroenterology, 1/1/2015
• (Sul864) Clinical correspondence of interstitial cells of cajal values from full thickness gastric biopsy in patients undergoing gastric stimulation for diabetic gastr...
  Patel C, Soota K, Yang X, El Jamal SM, Fraig MM, Beatty K, Miller E, Kedar A, Hughes MG, McElmurray L, Stocker AM, Abell TL, Gastroenterology, 1/1/2015
• (Sul420) Evaluating gastric mucosal nerve density in relation to full thickness biopsy, gastric emptying, symptoms and response to temporary gastric stimulation.
  Patel C, Yang X, Wendelschafer-Crabb G, Kennedy WR, Beatty K, Miller E, Kedar A, Hughes MG, McElmurray L, Fraig MM, Stocker AM, Abell TL, Gastroenterology, 1/1/2015
• (Tul963) Gastric electrical stimulation is effective in reducing symptoms of malignancy associated gastroparesis.
  Shah H, Wendorf G, Ahmed S, McElmurray L, Hughes MG, Miller E, Stocker AM, Abell TL, Gastroenterology, 1/1/2015
• (Sul422) Autonomic and enteric responses to temporary gastric electrical stimulation.
  Vermani S, Patel AA, Miller E, Beatty K, Stocker AM, Hughes MG, Rashed H, Kedar A, Abell TL, Gastroenterology, 1/1/2015
• Initiation and early results of an Alemtuzumab-induction program utilizing a Belatacept in kidney transplantation.
  Marvin MR, Eng M, Ouseph R, Jones CM, Davis E, Hughes M, American Journal of Transplantation, 1/1/2014
• Next generation sequencing of the hepatitis C virus transmitted during liver transplantation reveals selection within hypervariable region1.
  Hughes MG, Rouchka EC, Marvin MR, McClain CJ, Jonsson CB, American Journal of Transplantation, 1/1/2014
• Single center experience with Simeprevir/ Sofosbuvir combination therapy for recurrent hepatitis C virus infection in liver transplant recipients.
  Marsano LS, McClain CJ, Barve A, Goshko BA, Tatum RR, Cave MC, Crittenden N, Davis EG, Hughes MG, Jones CM, Marvin MR, American Association for the Study of Liver Diseases, 1/1/2014
• Is micro-RNA-122 (miR-122) an accurate biomarker for ischemia-reperfusion injury during liver transplantation?
  Hughes MG, Reddy SC, Brier M, McClain CJ, Jonsson CB, American Journal of Transplantation, 1/1/2013
• The presence of polyomavirus BK replication in urine or plasma correlate with significant renal impairment in renal transplant recipients.
  Eng M, Jones CM, Hughes MG, Davis E, Marvin MR, American Journal of Transplantation, 1/1/2013
• Characterization of the variability in uptake of Hepatitis C virus (HCV) by liver allografts during reperfusion.
  Hughes MG, Reddy S, Brier M, Marvin MR, Jones CM, Eng M, Jonsson C, American Journal of Transplantation, 1/1/2012
• Combined heart-liver transplantation in the United States.
  Cannon RM, Hughes MG, Jones CM, Eng M, Marvin MR, Journal for Surgical Research, 1/1/2012
• Impact of MicroRNA-122 (miR-122) and small RNA prdocution on Hepatitis C Viral (HCV) uptake by liver allografts during reperfusion.
  Hughes MG, Reddy SC, Brier M, McClain C, Jonsson CB, Hepatology, 1/1/2012
• Evolution of cytomegalovirus (CMV) and BK virus complications after kidney transplantation with Alemtuzumab induction.
  Hughes MG, Cannon RM, Ouseph R, Mackelaite L, Eng M, Jones CM, Marvin MR, American Journal of Transplantation, 1/1/2012
• Does BMI affect infection-related outcomes in the ICU?
  Smith RL, Chong TW, Hedrick TL, McElearney ST, Hughes MG, Evans HL, Sawyer RG, Pruett TL, Surg Infect, 1/1/2006
• Recapture of favorable infection rates with reintroduction of quarterly two-drug antibiotic rotation against gram-negative organisms.
  McElearney ST, Evans HL, Smith RL, Saalwachter AR, Chong TW, Hughes MG, Raymond DP, Pruett TL, Sawyer RG, Surg Infect, 1/1/2004
• Sex hormones and infectious outcomes in surgical patients.
  Evans HL, Saalwachter AR, McElearney ST, Smith RL, Chong TW, Hughes MG, Raymond DP, Pruett TL, Sawyer RG, Surg Infect, 1/1/2004
• The cost of gram negative resistance.
  Evans HL, Lafrak SN, Lyman J, Smith RL, Chong TW. McElearney ST, Saalwachter AR, Hughes MG, Raymond DP, Pruett TL, Sawyer RG, Crit Care Med, 1/1/2004
• Nature of GNR antibiotic resistance in antibiotic rotation.
  Evans HL, Milburn ML, Hughes MG, Smith RL, Chong TW, Raymond DP, Pelletier SJ, Pruett TL, Sawyer RG, Surg Infections, 1/1/2003
• Quarterly Vancomycin/Linezolid reduced resistant gram-positive infections in an Intensive Care Unit.
  Smith RS, Evans HL, Chong TW, Hughes MG, Raymond DP, Pelletier EJ, Popovsky K, Bledsoe K, Volles D, Scheld M, Pruett TL, Sawyer RG, 41st Meeting of IDSA Meeting Program, 1/1/2003
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Lectures

• The Natural History of Diabetes 3c and the Importance of Maintaining C-peptide Positivity after Total Pancreatectomy. 
  Chicago, IL - 1/30/2017
• Peripancreatic fat-derived stromal vascular fraction cells stimulate intra-islet endothelial cells to form peri-islet vessels in human islets. 
  Oxford, England - 1/22/2017
• Peri-islet vessels formation around human islets by stimulating intra-islet endothelial cells: Bioengineering approaches to improve islet survival after transplantation. 
  Oxford, England - 1/22/2017
• Bio-printed spheroids with human islets and adipose-derived stromal vascular fraction cells (SVF) using a 3D bio-printing technology for improving islet integrity and ... 
  Oxford, England - 1/22/2017
• Identifying optimal enzyme blend of collagenase and protease for obtaining high islet yield from young donor pancreases. 
  Oxford, England - 1/21/2017
• Low cost, collagenase-protease enzyme mixtures successfully used for isolating human islets from human research pancreata. 
  Oxford, England - 1/21/2017
• Beneficial effect of recombinant collagenases class I (rC1) and class II (rC2) on human islet function: Efficacy of low dose enzymes on pancreas digestion and yield. 
  Oxford, England - 1/21/2017
• Total Pancreatectomy with Islet Auto-Transplantation for Chronic Pancreatitis. 
  Indiana University School of Medicine, Indianapolis, IN, 2016; Bowling Green, KY, 2017 - 1/16/2017
• Bioengineering Human Islets to Form Peri-Islet Vessels from Intraislet Endothelial Cells for Improving Human Islet Function. 
  Chicago, IL - 1/2/2017
• Improved Method to Obtain High Islet Mass from Severely Fibrotic Pancreatitis Pancreases Intended for Clinical Islet Auto-Transplantation. 
  Chicago, IL - 1/1/2017
• Initial Experince with Total Pancreatectomy-Islet Auto-Transplantation (TP-IAT) for Chronic Pancreatitis at the University of Louisville. 
  Chicago, IL - 1/1/2017
• Islet Auto-Transplantation 
  Bethesda, MD - 1/25/2016
• Transplant Surgery Research 
  1/19/2016
• Peripancreatic fat-derived stromal vascular fraction (PPSVF) cells stimulate intra-islet endothelial cells to form peri-islet vessels (PIVs) in human islets. 
  Louisville, KY - 1/11/2016
• Improved islet isolation techniques yielded high islet mass even from severely fibrotic chronic pancreatitis pancreases (CPP) intended for clinical islet autotransplan... 
  Louisville, KY - 1/11/2016
• Identifying the effect of collagenase and protease enzyme blends on human pancreas digestion for improving islet yield and function. 
  Louisville, KY - 1/11/2016
• Islet auto-transplantation at the University of Louisville. 
  University of Louisville, Louisville, KY, 2015; Louisville, KY, 2015; Washington, DC, 2016 - 1/9/2016
• Neuromuscular evaluation of drug and device refractory patients with the symptoms of gastroparesis reveals a variety of abnormalities. 
  Washington, DC - 1/16/2015
• (Sul 422) Autonomic and enteric responses to temporary gastric electrical stimulation. 
  Washington, DC - 1/16/2015
• Gastric electrical stimulation is erffective in reducing symptoms of malignancy associated gastroparesis. 
  Washington, DC - 1/16/2015
• Correlation of mucosal nerve density with gastric electrical activity at baseline and after gastric stimulation in patients with gastroparesis. 
  Washington, DC - 1/16/2015
• Autonomic and enteric responses to temporary gastric electrical stimulation. 
  Washington, DC - 1/16/2015
• (Tul 963) Gastric electrical stimulation is effective in reducing symptoms of malignancy associated gastroparesis. 
  Washington, DC - 1/16/2015
• (Sul 420) Evaluating gastric mucosal nerve density in relation to full thickness biopsy, gastric emptying, symptoms and response to temporary gastric stimulation. 
  Washington, DC - 1/16/2015
• (Sul 851) Clinical correspondence of S100 levels on full thickness gastric biopsy. 
  Washington, DC - 1/16/2015
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