MichaelJHoltzmanMD
Pulmonology • Saint Louis, MOAsthma & COPD, Critical Care Medicine, Infectious Disease, Restrictive Lung Disease
Seldin Professor and Director, Pulmonary and Critical Care Medicine, Washington University School of Medicine
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Office
1 Barnes Jewish Hospital Plz
Dept Internal
Saint Louis, MO 63110Phone+1 314-362-8983Fax+1 314-362-8987
Education & Training
University of California (San Francisco)/FresnoFellowship, Pulmonary Disease and Critical Care Medicine, 1977 - 1980
Duke University HospitalResidency, Internal Medicine, 1975 - 1977
Northwestern University The Feinberg School of MedicineClass of 1975
Certifications & Licensure
CA State Medical License 1977 - Present
MO State Medical License 1987 - 2025- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Pulmonary Disease
Awards, Honors, & Recognition
- Member Association of American Physicians (AAP)
- Fellow American Association for the Advancement of Science (AAAS)
- Member American Society for Clinical Investigation (ASCI)
Clinical Trials
- Factors That Affect the Development of COPD Symptoms Start of enrollment: 2007 Oct 01
- Analyzing Lung Tissue in People With and Without Chronic Obstructive Pulmonary Disease Who Are Undergoing Lung Transplantation Start of enrollment: 2007 Oct 01
- Biomarkers and Genetic Factors Related to Emphysema Start of enrollment: 2007 Oct 01
Publications & Presentations
PubMed
- 352 citationsThe microbial metabolite desaminotyrosine protects from influenza through type I interferonAshley Steed, George P. Christophi, Gerard E. Kaiko, Lulu Sun, Victoria M. Goodwin
Science. 2017-08-04 - 111 citationsThe choroid plexus is an important circadian clock component.Jihwan Myung, Christoph Schmal, Sungho Hong, Yoshiaki Tsukizawa, Pia Rose
Nature Communications. 2018-03-14 - 46 citationsSARS-CoV-2 causes lung infection without severe disease in human ACE2 knock-in mice.Emma S. Winkler, Rita E. Chen, Fahmida Alam, Soner Yildiz, James Brett Case
Journal of Virology. 2021-10-20
Press Mentions
Lee to Lead Pulmonary & Critical Care DivisionNovember 22nd, 2022- Lee to Lead Pulmonary & Critical Care DivisionNovember 22nd, 2022
- Holtzman Receives Grant to Fund Lung Disease Drug DevelopmentJuly 13th, 2022
- Join now to see all
Grant Support
- Mechanisms In The Remodeling Of Lung StructureNational Heart, Lung, And Blood Institute2012
- New Immune Pathways For Epithelial RemodelingNational Heart, Lung, And Blood Institute2010–2012
- STAT 1 Modification For Antiviral DefenseNational Institute Of Allergy And Infectious Diseases2009–2012
- Epithelial Barrier Programs In Asthma And Allergic DiseaseNational Institute Of Allergy And Infectious Diseases2011
- Airway Epithelial Defense And InterferonNational Institute Of Allergy And Infectious Diseases2011
- Target Validation And Assay Development For Anti-Mucus TherapyNational Heart, Lung, And Blood Institute2011
- Basis Of Chronic Mucous Cell MetaplasiaNational Heart, Lung, And Blood Institute2008–2011
- Alveolar And Airway Mechanisms For COPDNational Heart, Lung, And Blood Institute2007–2011
- Airway Determinants: Innate Immune SignalingNational Heart, Lung, And Blood Institute2007–2011
- AdministrativeNational Heart, Lung, And Blood Institute2007–2011
- Administrative CoreNational Institute Of Allergy And Infectious Diseases2006–2011
- Principles In Pulmonary ResearchNational Heart, Lung, And Blood Institute1991–2011
- STAT1 Signaling And Airway Epithelial CellsNational Institute Of Allergy And Infectious Diseases2006–2010
- Innate And Adaptive Immune Signaling In AsthmaNational Institute Of Allergy And Infectious Diseases2006–2010
- Basis Of Airway Epithelial Cell SurvivalNational Heart, Lung, And Blood Institute2003–2007
- Basis Of Long-Term Virus-Induced Goblet Cell HyperplasiaNational Heart, Lung, And Blood Institute2003–2006
- SCOR: Mechanisms Of Airway Inflammation And RemodelingNational Heart, Lung, And Blood Institute2001–2005
- STAT1 Dependent Gene RegulationNational Heart, Lung, And Blood Institute1996–2005
- Virus-Inducible Remodeling Of Airway EpitheliumNational Heart, Lung, And Blood Institute2000–2002
- Virus Induced Gene Expression In Airway Epithelial CellsNational Heart, Lung, And Blood Institute1998–2002
- Mechanisms Of Airway InflammationNational Heart, Lung, And Blood Institute1996–2000
- Virus Inducible Remodeling Of Airway EpitheliumNational Heart, Lung, And Blood Institute1999
- Regulation Of Cell Adhesion In The AirwayNational Heart, Lung, And Blood Institute1995–1999
- Fiberoptic Bronchoscopy &Bronchial Biopsy In Asthma Patient And Normal ControlNational Center For Research Resources1996–1997
- Lung Epithelial Mechanisms For Mediator ReleaseNational Heart, Lung, And Blood Institute1988–1997
- Mechanisms Of Airway HyperreactivityNational Heart, Lung, And Blood Institute1985
Professional Memberships
- Member
- Fellow
- Fellow
- Member
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