MichaelHHandlerMD

PubMed

• 22 citations
  Identical twin sisters with Rubinstein-Taybi syndrome associated with Chiari malformations and syrinx.
  Lea K. Parsley, Gary Bellus, Michael H. Handler, Anne Chun Hui Tsai
  American Journal of Medical Genetics. Part A. 2011-11-01
• 44 citations
  Pediatric Brainstem Gangliogliomas Show BRAFV600E Mutation in a High Percentage of Cases
  Andrew M. Donson, Bette K. Kleinschmidt-DeMasters, Dara L. Aisner, Lynne T. Bemis, Diane Birks
  Brain Pathology. 2014-03-01
• 8 citations
  The utility of magnetic resonance imaging in pediatric trauma patients suspected of having cervical spine injuries.
  S Christopher Derderian, Krista Greenan, David M Mirsky, Nicholas V Stence, Sarah Graber
  The Journal of Trauma and Acute Care Surgery. 2019-12-01

Journal Articles

• Identification of FDA-approved oncology drugs with selective potency in high-risk childhood ependymoma  
  Donson AM, Amani V, Warner EA, Griesinger AM, Witt DA, Mulcahy Levy JM, Hoffman LM, Hankinson TC, Handler MH, Vibhakar R, Dorris K, Foreman NK, Mol Cancer Ther, 1/20/2018
• Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma  
  Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Ge..., Neuro Oncol, 1/1/2018
• Significance of FDG-PET hypermetabolism in children with intractable focal epilepsy  
  Shur S, Allen V, White A, Mirsky D, Stence N, O'Neill BR, Handler MH, Dudley R, Laoprasert P, Pediatric Neurosurgery, 1/1/2018
• Frontal and occipital horn ratio is associated with multifocal intraparenchymal hemorrhages in neonatal shunted hydrocephalus  
  Oushy S, Parker JJ, Campbell K, Palmer C, Wilkinson C, Stence NV, Handler MH, Mirsky DM, J Neurosurg Pediatr, 1/8/2017
• Modified hysterotomy closure technique for open fetal surgery  
  Zaretsky MV, Liechty KW, Galan HL, Behrendt NJ, Reeves S, Marwan AI, Wilkinson CC, Handler MH, Lagueux M, Crombleholme TM, Fetal Diagnosis and Therapy, 1/1/2017
• Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood  
  Amani V, Donson AM, Lummus SC, Prince EW, Griesinger AM, Witt DA, Hankinson TC, Handler MH, Dorris K, Vibhakar R, Foreman NK, Hoffman LM, J Neuropathol Exp Neurol, 1/1/2017
• Advancing Treatment for Pediatric Craniopharyngioma Consortium Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamanti...  
  Donson AM, Apps J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan ..., J Neuropathol Exp Neurol, 1/1/2017
• NF-KappaBeta upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma  
  Griesinger AM, Witt DA, Grob ST, Georgio Westover SR, Donson AM, Sanford B, Mulcahy Levy JM, Wong R, Moreira DC, DeSisto JA, Balakrishnan I, Hoffman LM, Handler MH, Jo..., Neuro Oncol, 1/1/2017
• Chordoma Occurs in Young Children With Tuberous Sclerosis  
  Dahl NA, Luebbert T, Loi M, Neuberger I, Handler MH, Kleinschmidt-DeMasters BK, Mulcahy Levy JM, J Neuropathol Exp Neurol, 1/1/2017
• Insular epilepsy surgery  
  Laoprasert P, Ojemann JG, Handler MH, Epilepsia, 1/1/2017
• Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors  
  Mulcahy Levy J, i Zahedi S, Griesinger AM, Morin A, Davies KD, Aisner DL, Kleinschmidt-DeMasters BK, Fitzwalter BE, Goodall ML, Thorburn J, Amani V, Donson AM, Birks D..., eLife, 1/1/2017
• Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma  
  Prince E, Balakrishnan I, Shah M, Mulcahy-Levy J, Greisinger A, Alimova I, Birks D, Donson A, Remke M, Taylor MD, Handler MH, Foreman NK, Venkataraman S, Vibhakar R, Oncotarget, 1/19/2016
• The Emergence of Zoonotic Onchocerca lupi Infection in the United States-A Case-Series  
  Cantey PT, Weeks J, Edwards M, Rao S, Ostovar GA, Dehority W, Alzona M, Swoboda S, Christiaens B, Ballan W, Hartley J, Terranella A, Weatherhead J, Dunn JJ, Marx DP, H..., Clin Infect Dis, 1/15/2016
• Use of magnetic resonance imaging to detect occult spinal dysraphism in infants  
  O'Neill BR, Gallegos D, Herron A, Palmer C, Stence NV, Hankinson TC, Corbett Wilkinson C, Handler MH, J Neurosurg Pediatr, 1/2/2016
• Routine perioperative ketorolac administration is not associated with hemorrhage in pediatric neurosurgery patients  
  Richardson MD, Palmeri NO, Williams SA, Torok MR, O'Neill BR, Handler MH, Hankinson TC, J Neurosurg Pediatr, 1/1/2016
• Short-term mortality following surgical procedures for the diagnosis of pediatric brain tumors: outcome analysis in 5533 children from SEER, 2004-2011  
  Hankinson TC, Dudley RW, Torok MR, Patibandla MR, Dorris K, Poonia S, Wilkinson CC, Bruny JL, Handler MH, Liu AK, J Neurosurg Pediatr, 1/1/2016
• Outcome of hospital discharge on postoperative Day 1 following uncomplicated tethered spinal cord release  
  Poonia S, Graber S, Corbett Wilkinson C, O'neill BR, Handler MH, Hankinson TC, J Neurosurg Pediatr, 1/1/2016
• Response to Journal Club: Pediatric Low-Grade Ganglioglioma: Epidemiology, Treatments, and Outcome Analysis of 348 Children From the Surveillance, Epidemiology, and En...  
  Dudley RW, Torok MR, Hoffman L, Levy JM, Handler MH, Liu AK, Hankinson TC, Neurosurgery, 1/1/2016
• Atypical pediatric ganglioglioma is common and associated with a less favorable clinical course  
  Patibandla MR, Ridder T, Dorris K, Torok MR, Liu AK, Handler MH, Stence NV, Fenton LZ, Hankinson TC, J Neurosurg Pediatr, 1/1/2016
• A cervical spine mass caused by Onchocerca lupi  
  Dudley RW, Smith C, Dishop M, Mirsky D, Handler MH, Rao S, Lancet, 1/3/2015
• Surgery for infants with catastrophic epilepsy: an analysis of complications and efficacy  
  Kumar RM, Koh S, Knupp K, Handler MH, O'Neill BR, Childs Nerv Syst, 1/1/2015
• Interleukin-6/STAT3 pathway signaling drives an inflammatory phenotype in Group A ependymoma  
  Griesinger AM, Josephson RJ, Donson AM, Mulcahy Levy JM, Amani V, Birks DK, Hoffman LM, Furtek SL, Reigan P, Handler MH, Vibhakar R, Foreman NK, Cancer Immunol Res, 1/1/2015
• Incidence of seizures on continuous EEG monitoring following traumatic brain injury in children  
  O'Neill BR, Handler MH, Tong S, Chapman KE, J Neurosurg Pediatr, 1/1/2015
• Pediatric choroid plexus tumors: epidemiology, treatments, and outcome analysis on 202 children from the SEER database  
  Dudley RW, Torok MR, Gallegos D, Liu AK, Handler MH, Hankinson TC, J Neurooncol, 1/1/2015
• Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma  
  Hoffman LM, Donson AM, Nakachi I, Griesinger AM, Birks DK, Amani V, Hemenway MS, Liu AK, Wang M, Hankinson TC, Handler MH, Foreman NK, Acta Neuropathol, 1/1/2014
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Books/Book Chapters

• Pediatric Neurosurgery: Tricks of the Trade 
  Chapter: "Hemispherotomy and Hemispherectomy." 
  Handler MH and O'Neill BEditors: Cohen AR.Thieme2015
• Pediatric Decision Making 
  Chapter: "Evaluation of a Child with a Ventricular Shunt for Hydrocephalus." 
  Handler MH and Batchelder PEditors: Berman, S.Harcourt BraceEdition 4th,2003

Abstracts/Posters

• "Optimal treatment options for arachnoid cyst in infants less than 18 months."
  Handler MH, Graber S, Battista-Silverman L, Wilkinson C, O'Neill B, Hankinson TC, 2017 Consensus Conference on Arachnoid Cysts, Rome, 1/23/2017
• "Primary Intracranial Ewing's Sarcoma: Report of Three Cases"
  Handler MH, Madden J, Hankinson TC, Kleinschmidt-Demasters BK, Foreman NK, 44th Annual Meeting of the International Society for Pediatric Neurosurgery, Kobe, Japan, 1/23/2016
• "Vascular Abnormalities after Treatment for Craniopharyngioma."
  Handler MH, Batchelder P, Hankinson TC, Foreman NK, Liu, A, Vibhakar R, 44th Annual Meeting of the International Society for Pediatric Neurosurgery, Kobe, Japan, 1/23/2016
• "MRI Utility in C-Spine clearance following pediatric trauma."
  Handler MH, Greenan K, Mirsky D, Graber S, Hubbell N, Stence N, 26th Congress of the European Society for Pediatric Neurosurgery, Bonn, Germany, 1/1/2016
• "Thirty day reoperation rate for pediatric shunt surgery: a good quality measure?"
  Kumar F, Graber S, Palmer C, Hankinson T, Handler MH, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, Orlando, FL, 1/1/2016
• "International survey on the management of lumbosacral cutaneous stigmata in infants with suspected occult spinal dysraphism."
  Svokos K, Silvernan LB, Graber S, Handler MH, O'Neill B, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, Orlando, FL, 1/1/2016
• "International Survey on operative management of infants with occult spinal dysraphism."
  Svokos K, Silvernan LB, Graber S, Handler MH, O'Neill B, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, Orlando, FL, 1/1/2016
• "New Fetal Myelomeningocele Program: Oversight and Initial Experience."
  Handler MH, Liechty K, Galan H, Zaretsky M, Behrendt N, Marwan R, Wilkinson CW, Myers M, Mirsky D, Crombleholme TM, Annual Meeting of the International Society of Pediatric Neurosurgeons, Izmir, Turkey, 1/1/2015
• "Cognitive Outcomes in Medulloblastoma Patients with Cerebellar Mutism and Shunted Hydrocephalus."
  Batchelder P, Wilkening G, Hankinson TC, Foreman NK, Handler MH, 16th International Symposium on Pediatric Neuro-Oncology, Singapore, 1/28/2014
• "Disseminated leptomeningeal PNET without a primary tumor: 5 cases."
  Handler MH, Hankinson T, Madden J, Kleinschmidt-Demasters BK, Foreman NK, 16th International Symposium on Pediatric Neuro-Oncology, Singapore, 1/28/2014
• "Knock-down of YAP1 reduces proliferation and survival of !T/RT cells."
  Birks DK, Griesinger A, Amani V, Donson AM, Posner RK, Dunham C Kleinschmidt-Demasters BK, Handler MH, Vibhakar R, Foreman NK, 16th International Symposium on Pediatric Neuro-Oncology, Singapore, 1/28/2014
• "Epilepsy surgery in infants under a year of age."
  Handler MH, Kumar R, Koh S, Laoprasert P, Knupp K, O'Neill B, 24th Congress of the European Society of Pediatric Neurosurgery, Rome, 1/4/2014
• "Disseminated leptomeningeal PNET without a primary tumor: 5 cases."
  Handler MH, Hankinson TC, Madden J, Kleinschmidt-Demasters BK, Foreman N, Annual Meeting of the International Society for Pediatric Neurosurgery, Rio de Janeiro, 1/1/2014
• "BRAFv600E Mutations in Brainstem Gangliogliomas."
  Handler MH, Donson K, Kleinschmidt-Demasters B, Bemis L, Aisner D, Birks D, Levy J, Smith A, Rush S, Foreman N, Annual Meeting of the American Society of Pediatric Neurosurgeons, Guanacaste, Costa Rica, 1/1/2014
• "Ketorolac in Pediatric Neurosurgery."
  Handler MH, Richardson MD, Palmeri N, Williams S, Turok M, Hankinson TC, Annual Meeting of the International Society for Pediatric Neurosurgery, Rio de Janeiro, 1/1/2014
• "Epilepsy Surgery in Infants under a year of age."
  O'Neill B, Koh S, Laoprasert P, Knupp K, Handler MH, 81st Annual Scientific Meeting of the American Association of Neurological Surgeons, New Orleans, LA, 1/27/2013
• "Incidence of seizures on continuous EEG after traumatic brain injury in children."
  Handler MH, Wolter-Warmerdam K, O'Neill B, Chapman K, Annual Meeting of the International Society of Pediatric Neurosurgeons, Mainz, Germany, 1/1/2013
• "Fractionated Stereotactic Radiosurgery for Recurrent Pediatric Ependymomas."
  Handler MH, Hoffman L, Hankinson TC, Foreman N, Liu A, Annual Meeting of the American Society of Pediatric Neurosurgeons, Kauai, HI, 1/1/2013
• "High throughput sequencing reveals SMARCB1 loss results instable genome but variable transcriptome in AT/RTs."
  Birks D, Jones K, Donson, A, Griesinger A, Amani V, Handler MH, Vibhakar R, Foreman, Annual Meeting of the Society for Neuro-oncology, Ft. Lauderdale, FL, 1/1/2013
• "Pediatric choroid plexus tumors: epidemiology, treatments and outcome analysis on 198 children from the SEER database."
  Dudley R, Torok M, Gallegos D, Liu A, Handler MH, Hankinson TC, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, Toronto, 1/1/2013
• "Safety of perioperative ketorolac use in pediatric neurosurgery patients."
  Richardson MD, Palmeri NO, Williams S, Torok MR, Handler MH, Hankinson TC, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, St. Louis, MO, 1/1/2012
• "Patterns of care for craniopharyngioma: Survey of AANS membership."
  Serrano CA, Williams SA, Palmeri NO, Torok MR, Handler MH, Liu AK, Hankinson TC, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, St. Louis, MO, 1/1/2012
• "Surgical Outcome and Prognostic Factors in Children with Medically Intractable Epilepsy caused by Focal Cortical Dysplasia."
  O'Neill BR, Laoprasert P, Shmueli D, White A, Handler MH, Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS, St. Louis, MO, 1/1/2012
• "ATRTs: unusual clinical variants manifest typical microarray profiles."
  Batchelder P, Birks D, Donson AM, Kleinschmidt-Demasters BK, Foreman N, Handler MH, 15th International Symposium on Pediatric Neuro-Oncology, Toronto, 1/1/2012
• "Diffuse pontine PNET: confounding the diagnosis of DIPGs."
  Handler MH, Sufit A, Donson A, Birks D, Patel P, Foreman NK, 15th International Symposium on Pediatric Neuro-Oncology, Toronto, 1/1/2012
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Lectures

• "Vein of Galen Aneurysmal Malformations." 
  Haikou, China - 1/13/2018
• "Epilepsy Surgery-A Conceptual Framework." 
  Haikou, China - 1/13/2018
• "Focal Epilepsy-Surgical Strategies." 
  Haikou, China - 1/13/2018
• "Lumbosacral Lipomas." 
  Haikou, China - 1/13/2018
• "Third Ventricular Tumors, Interesting Cases." 
  Haikou, China - 1/13/2018
• "Pediatric Brain Tumors, Interesting Cases." 
  Haikou, China - 1/13/2018
• "The Tethered Cord." 
  Children's Hospital Colorado, Aurora, CO - 1/9/2018
• "Hycrocephalus and its Management." 
  Children's Hospital Colorado, Aurora, CO - 1/2/2018
• "How I do it: temporal lobectomy." 
  Hilton, South Africa - 1/8/2017
• "How I do it: lesional epilepsy." 
  Hilton, South Africa - 1/8/2017
• "What to do when your epilepsy operation fails?" 
  Hilton, South Africa - 1/8/2017
• "Special challenges: low grade temporal lobe tumors." 
  Hilton, South Africa - 1/8/2017
• "Dermal sinus, dermoids and epidermoids." 
  Hilton, South Africa - 1/8/2017
• "Antenatal surgery-High risk, low benefit?" 
  Hilton, South Africa - 1/8/2017
• "Fetoscopic closure of myelomeningocele: not ready for prime time." 
  Maui, HI - 1/1/2017
• "Regionalize Fetal Myelomeningocele Care Centers." 
  Maui, HI - 1/1/2017
• "Evolution of Neurosurgical Decision Making." 
  Liverpool, England - 1/12/2016
• "Hydrocephalus after Hemispherectomy." 
  Omni Interlocken Hotel, Broomfield, CO - 1/9/2016
• "Brain Stem Tumors." 
  Guangzhou, China - 1/2/2016
• "Epilepsy and Brain Tumors." 
  Guangzhou, China - 1/2/2016
• "Posterior Fossa Ependymomas." 
  Guangzhou, China - 1/2/2016
• "Supratentorial Ependymomas." 
  Guangzhou, China - 1/2/2016
• "30 day return to OR after VP shunt operation: a quality measure?" 
  Paris - 1/1/2016
• "Decompressive Craniectomy in Children" 
  Park City, UT - 1/15/2015
• "Hydrocephalus and shunts for neurologists." 
  1/17/2014
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Other

• "Cervical Spine Clearance in the Obtunded Child." 
  Handler MH, Debate-Western Pediatric Trauma Conference 2015
  Park City, UT - 1/15/2015
• "Prenatal Closure Should Be Standard in Management of Myelomeningocele." 
  Handler MH, Debate-Meeting of the Joint Section on Pediatric Neurological Surgery of the AANS and CNS
  Austin, TX - 1/1/2011