MatthiasASalatheMD

PubMed

• The Pulmonary Perspective: Can E-Cigarettes Be Labeled as Safe Smoking Cessation Tools?
  Charlotta Pisinger, Claus F Vogelmeier, Ava C Wilson, Matthias Salathe, Robert Tarran
  American Journal of Respiratory and Critical Care Medicine. 2024-10-01
• Cystic fibrosis.
  Marcus A Mall, Pierre-Régis Burgel, Carlo Castellani, Jane C Davies, Matthias Salathe
  Nature Reviews. Disease Primers. 2024-08-08
• 1 citations
  ETD001: A novel inhaled ENaC blocker with an extended duration of action in vivo.
  Henry Danahay, Clive McCarthy, Thomas Schofield, Roy Fox, Holly Charlton
  Journal of Cystic Fibrosis. 2024-06-07

Journal Articles

• The clinical features of bronchiectasis associated with alpha-1 antitrypsin deficiency, common variable immunodeficiency and primary ciliary dyskinesia--results from t...  
  Eden E., Choate R., Barker A., Addrizzo-Harris D., Aksamit T.R., Daley C.L., Daniels M.L.A., DiMango A., Fennelly K., Griffith D.E., Johnson M.M., Knowles M.R., Meters..., Chronic Obstr. Pulm. Dis., 1/1/2019
• Cigarette smoke exposure reduces leukemia inhibitory factor levels during respiratory syncytial viral infection  
  Poon J. Campos M., Foronjy R.F., Nath S., Gupta G., Railwah C., Dabo A.J., Baumlin N., Salathe M., Geraghty P., Int. J. Chron. Obstruct. Pulmon. Dis, 1/1/2019
• Protein Phosphatase 2A Prevents Cigarette Smoke-Induced Cathepsin S and Loss of Lung Function  
  Doherty D.F., Nath S., Foronjy R.F., Ohlmeyer M., Poon J., Dabo A.J., Salathe M., Birrell M., Belvisi M., Baumlin N., Kim M.D., Weldon S., Taggart C., and Geraghty P., Am., J. Respir. Crit. Care Med., 1/1/2019
• Chronic cigarette smoke exposure subdues PP2A activity by enhancing expression of the oncogene CIP2A  
  Nath S., Ohlmeyer M., Salathe M., Poon J., Baumlin N., Foronjy R.F., and Geraghty P., Am. J. Respir. Cell Mol. Biol, 1/1/2018
• VX-659-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles  
  Davies J.C., Moskowitz S.M., Brown C., Horsley A., Mall M.A., McKone E.F., Plant B.J., Prais D., Ramsey BW1, Taylor-Cousar JL1, Tullis E1, Uluer A1, McKee CM1, Roberts..., N. Engl. J. Med., 1/1/2018
• Catch the Wave: Quantitatively Assessing Airway Ciliary Function as a Diagnostic Tool (editorial)  
  Kim M.D., Salathe M., Am. J. Respir. Cell Mol. Biol., 1/1/2018
• Fibroblast Growth Factor 23 and Klotho Contribute to Airway Inflammation  
  Krick S., Grabner A., Baumlin N., Yanucil C., Helton S., Grosche A., Sailland J., Geraghty P., Viera L., Russell D.W., Wells J.M., Xu X., Gaggar A., Barnes J., King G...., Eur. Respir. J., 1/1/2018
• Differences in vaping topography in relation to adherence to exclusive electronic cigarette use in veterans  
  Guerrero A.M., Diaz L.V.L., Balestrini K., Holt G., Mirsaeidi M., Calderon-Candelario R., Whitney P., Salathe M., Campos M.A., PlosOne, 1/1/2018
• The Prevalence and Significance of Staphylococcus aureus in Patients with non-Cystic Fibrosis Bronchiectasis  
  Metersky M.L., Aksamit T.R., Barker A., Choate R., Daley C.L., Daniels L.A., DiMango A., Eden E., Griffith D., Johnson M., Knowles M., O�Donnell A.E., Olivier K., Sala..., Ann. Thorac. Ann Am Thorac Soc, 1/1/2018
• Pharmacotherapy for non-cystic fibrosis bronchiectasis: results from an NTM Info & Research patient survey and the Bronchiectasis and NTM Research Registry  
  Henkle E., Aksamit T.R., Barker A.F., Curtis J.R., Daley C.L., Daniels M.L., DiMango A., Eden E., Fennelly K., Griffith D.E., Johnson M., Knowles M.R., Leitman A., Lei..., Chest, 1/1/2017
• Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways  
  Schmid A., Sailland J., Novak L., Baumlin N., Fregien N., and Salathe M., FEBS lett, 1/1/2017
• Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia  
  Krick S., Baumlin N., Aller S.P., Aguiar C., GrabnerA., Sailland J., Mendes E., Schmid A., Qi L., David N.V., Geraghty P., King G., Birket S., Rowe S.M., Faul C., and ..., Sci Rep, 1/1/2017
• Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells  
  Sailland J., Grosche A., Baumlin N., Dennis J.S., Schmid A., Krick S., and Salathe M, Sci. Rep, 1/1/2017
• Frequency of untreated hypogammaglobulinemia in bronchiectasis  
  Ruffner M.A., Aksamit T.R., Thomashow B., Choate R., DiMango A., Turino G.M., O'Donnell A.E., Johnson M.M., Olivier K.N., Fennelly K., Daley C.L., Winthrop K.L., Meter..., Ann Allergy Asthma Immunol., 1/1/2017
• Bronchiectasis in Adult Non-Cystic Fibrosis Patients: A First Look at the United States Bronchiectasis Research Registry  
  Aksamit T., O'Donnell A., Barker A., Olivier K., Winthrop K., Daniels M.L., Johnson M., Eden E., Griffith D., Knowles M., Metersky M., Salathe M., Thomashow B., Tino G..., Chest, 1/1/2017
• Wood combustion particles induce adverse effects to normal and diseased airway epithelia  
  Krapf M., Kunzi L., Allenbach S., Bruns E.A., Gavarini I., El-Haddad I., Slowik J.G., Prevot A.S., Drinovec L., Mocnik G., Dumbgen L., Salathe M., Baumlin N., Sioutas ..., Environ Sci Process Impacts, 1/1/2017
• Association of systemic inflammation, adiposity, and metabolic dysregulation with asthma burden among Hispanic adults  
  Rastogi D., Jung M., Strizich G., Shaw P.A., Davis S.M., Klein O.L., Penedo F.J., Ries A.L., Daviglus M.L., Moreiras J.J., Salathe M.A., Celed�n J.C., Isasi C.R., Kapl..., Respir. Med, 1/1/2017
• A patient-based analysis of the geographic distribution of MAC, M abscessus and M kansasii infections in the US  
  Mirsaeidi M., Ann, V., Leitman P., Sharifi A., Wisliceny S., Leitman A., Schmid A., Campos M., Falkinham J., Salathe M., Chest, 1/1/2017
• Randomized Trial of Liposomal Amikacin for Inhalation in Nontuberculous Mycobacterial Lung Disease  
  Olivier K.N., Griffith D.E., Eagle G., McGinnis II J.P., Micioni L., Liu K., Daley C.L., Winthrop K.L., Ruoss S., Addrizzo-Harris D.J., Flume P.A., Dorgan D., Salathe ..., Am J Respir Crit Care Med, 1/1/2017
• Glutathione peroxidase-1 suppresses the unfolded protein response upon cigarette smoke exposure  
  Geraghty P., Baumlin N., Salathe M., Foronjy R.F. and D'Armiento J.M., Mediators Inflamm., 1/1/2016
• Chronic electronic cigarette exposure in mice induces COPD in a nicotine-dependent manner  
  Garcia-Arcos I., Geraghty P., Baumlin N., Campos M., Dabo A.J., Jundi B., Cummins N., Eden E., Salathe M.* and Foronjy R.*, Thorax, 1/1/2016
• TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice  
  Foronjy R.F., Salathe M., Dabo A.J., Baumlin N., Cummins N., Eden E., and Geraghty P, Am. J. Physiol - Lung Cell Mol. Physiol., 1/1/2016
• Optimal lentivirus production and cell culture conditions necessary to successfully transduce primary human bronchial epithelial cells  
  Baumlin N., Salathe M., Fregien N., J. Vis. Exp., 1/1/2016
• Protein tyrosine phosphatase 1B negatively regulates S100A9-mediated lung damage during respiratory syncytial virus exacerbations  
  Foronjy R.F., Ochieng P.O., Salathe M.A., Dabo A.J., Eden E., Baumlin N., Cummins N., Barik S., Campos M., Thorp E.B. and Geraghty P, Mucosal Immunol., 1/1/2016
• Is Gastroparesis Found More Frequently in Patients with Cystic Fibrosis? A Systematic Review  
  Corral J.E., Dye C.W., Mascarenhas M.R., Barkin J.S., Salathe M., and Moshiree B, Scientifica, 1/1/2016
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Books/Book Chapters

• The Pulmonary Epithelium 
  Chapter: Structure and function of cilia 
  Page 111.0 - 125.0Schmid A., Salathe MEditors: Proud D.John Wiley & Sons2008
• Chronic obstructive pulmonary disease, a practical guide to management 
  Chapter: Mucociliary clearance 
  Page 189.0 - 200.0El-Chemaly S., Wanner A., Salathe MEditors: Stockley R., Rennard S., Rabe K., Celli B..Blackwell Publishing, Oxford2006
• Encyclopedia of Respiratory Medicine. 
  Chapter: Primary ciliary dyskinesia 
  Page 485.0 - 488.0Mitchison H., Salathe M., Leigh M., and Carson J.L.Editors: Laurent G.J., Shapiro S.D..Academic Press, New York2006
• Chemistry and Biology of Hyaluronan. 
  Chapter: Hyaluronan in the airways 
  Page 323.0 - 337.0Forteza R.M., Conner G.E., Salathe MEditors: Garg H.G. & Hales C.A..Elsevier Ltd.2004
• Cilia and mucus; from development to respiratory defense 
  Chapter: Modeling the response of mammalian ciliary beating to changes in cytoplasmic calcium 
  Page 59.0 - 66.0Salathe M. and Bookman R.J.Editors: Salathe M., Satir P., Adler K.B., Boucher R.C..Marcel Dekker, Inc2001
• Cilia, mucus, and mucociliary interactions. 
  Chapter: Is bacterial colonization of the airways relevant? 
  Page 343.0 - 348.0Wanner A., Salathe M., Kobayashi K., Abraham W.M., Seybold Z., Jackowski J.T.Editors: Baum G.L., Priel Z., Roth Y., Liron N., Ostfeld E.Marcel Dekker, Inc.1998
• The Lung: Scientific Foundations 
  Chapter: Mucociliary clearance. 
  Page 2295. - 2308.Salathe M., O'Riordan T.G., and Wanner A.Editors: Crystal R.G., West J.B., Weibel E.R., and Barnes P.J..Lippincott RavenEdition Seco,1997
• Respiratory Infections. 
  Chapter: Nonspecific host defenses: Mucociliary clearance and cough 
  Page 17.0 - 32.0Salathe M., Wanner A.Editors: Niederman M.S., Sarosi G.A., Glassroth J..W.B. Saunders1994
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Abstracts/Posters

• Protein Phosphatase 2A Prevents Cigarette Smoke-Induced Cathepsin S and Loss of Lung Function.
  Nath S., Doherty D.F., Foronjy R.F., Ohlmeyer M., Poon J., Dabo A.J., Salathe M.A., Birrell M., Belvisi M., Baumlin N., Kim M.D., Weldon S., Taggart C., Geraghty P, Am. J. Respir. Crit. Care Med., 1/1/2019
• Downregulation of the RNA Binding Protein HuR Correlates with Enhanced Expression of Senescence Markers in COPD Bronchial Epithelial Cells.
  Wyman A.E., Dabo A.J., Ezegbunam W., Garcia-Arcos I., Baumlin-Schmid N., Salathe M.A., Geraghty P., Foronjy R.F., Am. J. Respir. Crit. Care Med., 1/1/2019
• E-cig Vapors Cause CFTR Dysfunction and Mucosal Inflammation in Never-Smokers In Vitro and In Vivo.
  Chung S., Baumlin N., Dennis J.S., Whitney P.L., Aguiar C., Paredes Aller S., Mendes E.S., Schmid A., Kim M.D., Salathe M.A., Am. J. Respir. Crit. Care Med., 1/1/2019
• Nasal Inflammation Is Maintained in Cigarette Smokers Who Switch to E-cigarettes.
  Kim M., Baumlin N., Dennis J.S., Whitney P., Guerrero-Cignarella A.M., Campos M., Aguiar C., Paredes-Aller S., Schmid A., Mendes E.S., Salathe M.A., Am. J. Respir. Crit. Care Med, 1/1/2019
• E-Liquid with Nicotine Causes Mucociliary Dysfunction Via TRPA1 Receptors in a Novel Large Animal Model of Exposure.
  Baumlin N., Kim M., Chung S., Whitney P., Sabater J.R., Abraham W.M., Salathe M, Am. J. Respir. Crit. Care Med., 1/1/2019
• Cigarette Smoke Exposure Reduces Leukemia Inhibitory Factor Levels During Respiratory Syncytial Viral Infection
  Poon J., Campos M.A., Foronjy R.F., Nath S., Gupta G., Railwah C., Dabo A.J., Baumlin N., Salathe M.A., Geraghty P., Am. J. Respir. Crit. Care Med., 1/1/2019
• Cigarette Smoke Induced Inhibition of Sphingomyelin Synthase 2 Activity Modulates Airway Resistance.
  Gupta G., Railwah C.N., Poon J., Wadgaonkar R., Salathe M.A., Baumlin N., Huan C., Foronjy R.F., Jiang X.-C., Geraghty P., Am. J. Respir. Crit. Care Med, 1/1/2019
• Oral Microbiome Differences Associated with Replacing Tobacco Smoking with Electronic Cigarette Vaping.
  Campos M.A. , Guerrero A.M., Calderon Candelario R.A., Holt G.E., Mirsaeidi M., Mende R., Salathe M.A., Perez V., Benarjee S., Am. J. Respir. Crit. Care Med., 1/1/2019
• Airway Clearance in Non-Cystic Fibrosis Bronchiectasis: Analysis from the United States Bronchiectasis Research Registry.
  Basavaraj A., Choate R., Addrizzo-Harris D.J., Aksamit T.R., Barker A.F., Daley C.L., Daniels L.A., Eden E., DiMango A.M., Fennelly K.P., Griffith D.E., Johnson M.M., ..., Am. J. Respir. Crit. Care Med., 1/1/2019
• Pseudomonas Aeruginosa Associated with Severity of Non-Cystic Fibrosis Bronchiectasis Measured by the Modified Bronchiectasis Severity Score (BSI) and the FACED: The U...
  Choate R., Aksamit T.R., Mannino D.M., Sone G.A., Addrizzo-Harris D.J., Barker A.F., Basavaraj A., Daley C.L., Daniels L.A., Eden E., DiMango A.M., Fennelly K.P., Grif..., Am. J. Respir. Crit. Care Med., 1/1/2019
• Novel AntiAging Strategies to Inhibit the Effect of Bronchial Cell Senescence on Mucociliary Dysfunction.
  Krick S., Garth J., Adewale A.T., Shei R.-J., Tang L.P., Helton E.S., Denson R., Zaharias R., King G., Sailland J., Kunzi L., Baumlin N., Salathe M.A., Rowe S.M., Barn..., Am. J. Respir. Crit. Care Med., 1/1/2019
• Chronic Losartan Treatment Improves Lumacaftor�s Rescue of TGF-b1-Induced Mucociliary Dysfunction In Vitro
  Chung S., Yoshida M., Baumlin N., Kim M., Salathe M., Pediatric Pulmonology, 1/1/2018
• Hyperglycemia Causes Ion ChannelInduced Mucociliary Dysfunction.
  Kim M., Baumlin N., Dennis J.S., Yoshida M., Salathe, M., Pediatric Pulmonology, 1/1/2018
• Brevenal Increases Ciliary Beat Frequency and Particle Diffusion In Airway Surface Liquid Of Cystic Fibrosis Human Bronchial Epithelial Cells With Nonsense Mutations.
  Cohen I., Milla C., Salathe M., Baumlin N., Chung S., Bourdelais A., Baden D., Pediatric Pulmonology, 1/1/2018
• A Novel Targeted RNAi Molecule Delivery Platform for The Therapeutic Inhibition of ENaC In Cystic Fibrosis Lung Disease.
  Bush E.W., Nicholas A., Li X., Kuipers I., Hamilton H., Hegge J., Zhu R., Chen B., Srivastava J., Schluep T., Baumlin, N., Salathe M., Shei R., Rowe S.M., Dickey B.F.,..., Pediatric Pulmonology, 1/1/2018
• Georgiopoulos A. Development of A CF-Specific CBT Intervention to Prevent Depression and Anxiety in Adults with CF
  Friedman D., Pinsky H., Quittner A.L., Salathe M., Smith B., Pediatric Pulmonology, 1/1/2018
• The Clinical Features of Bronchiectasis Associated with Alpha-1 Antitrypsin Deficiency, Common Variable Immunodeficiency, and Primary Ciliary Dyskinesia.
  Choate R., Eden E., Addrizzo-Harris D.J., Aksamit T.R., Daley C.L., Daniels L.A., DiMango A.M., Fennelly K.P., Griffith D.E., Johnson M.M., Knowles M.R., Metersky M.L...., Am. J. Respir. Crit. Care Med, 1/1/2018
• Cigarette Smoke Exposure of Airway Epithelial Cells Induces Specific NOTCH Signaling to Change the Balance of MUC5B and MUC5AC Expression
  Baumlin N., Dennis J.S., Aguiar C., Paredes-Aller S., Schmid A., Mendes E.S., Kim M., Salathe M., Am. J. Respir. Crit. Care Med, 1/1/2018
• Transcriptomic Analysis of Early Airway Epithelial Inflammatory Responses.
  Langley R.J., Hussain S.S., Baumlin N., Nair M., Salathe M.A., Chand H.S., Am. J. Respir. Crit. Care Med., 1/1/2018
• Correlation of Ambient Particle Characteristics and Adverse Effects of Reactive Oxygen Species (ROS) to Normal and Diseased Airway Epithelia.
  Leni Z., Cassagnes L.E., Haddad I.E., Baumlin N., Salathe M.A., Baltensperger U., Dommen J., Geiser M., Am. J. Respir. Crit. Care Med, 1/1/2018
• Evaluating Adverse Effects of Aerosols from Different Electronic Cigarettes to Airway Epithelia by Realistic In Vitro Technologies
  Delaval M., Egli D., Jonsdottir H.R., Sch�pfer P., Baumlin N., Salathe M.A., Burtscher H., Geiser M., Am. J. Respir. Crit. Care Med, 1/1/2018
• Never-Smokers Develop Mucosal Inflammation and CFTR Dysfunction Upon Vaping Nicotine-Free E-Liquid for One Week.
  Kim M., Baumlin N., Dennis J.S., Whitney P., Arana J., Aguiar C., Paredes Aller S., Mendes E., Schmid A., Salathe M.A., Am. J. Respir. Crit. Care Med, 1/1/2018
• Nicotine Activates Epithelial TRPA1 Receptors to Cause Mucociliary Dysfunction.
  Chung S., Moore R., Dennis J.S., Baumlin N., Kim M.D., Salathe M.A., Am. J. Respir. Crit. Care Med, 1/1/2018
• sGC Stimulators Modulate BK Channel Activity in Human Airway Epithelial Cells.
  Kim M., Pantoja Y., Yoshida M., Baumlin N., Salathe M.A, Am. J. Respir. Crit. Care Med, 1/1/2018
• Losartan Demonstrates Anti-Inflammatory Properties in Challenged CF Cells In Vitro and in a CF Sheep Model In Vivo.
  Salathe, M., Baumlin, N., Sailland-Tschudi, J., Whitney, P., Dennis, J.S., Sabater, J., Abraham, W.M., Pediatric Pulmonology, 1/1/2017
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Lectures

• Is the airway simply a renal tubule? Lessons from Cystic Fibrosis Research 
  Kidney Institute University of Kansas Medical Center - 1/1/2019
• Vaping Research 
  1/1/2019
• Overview of Health impact of e-cigarette use or vaping 
  1/1/2019
• E-cigarette vapor: friend or foe? 
  University of Kansas Medical Center - 1/1/2018
• Repurposing approved medications to improve mucociliary dysfunction in cystic fibrosis 
  University of Kansas Medical Center - 1/1/2018
• Repurposing anti-inflammatory medications to improve mucociliary dysfunction in cystic fibrosis 
  University of Pittsburgh - 1/1/2017
• Regulation of Motile Cilia � Puzzling Tale of Splice Variants 
  1/1/2017
• Angiotensin receptor blockers reveal anti-inflammatory properties to improve mucociliary dysfunction in CF cells in vitro and in an ovine CF model in vivo 
  1/1/2017
• Could this be CF? 
  University of Miami - 1/1/2017
• Novel anti-inflammatory therapy for smoke-induced mucociliary dysfunction 
  SUNY Downstate - 1/1/2017
• Difficult diagnostic case 
  St. Mary�s Medical Center - 1/1/2016
• Exposure of Tobacco Smoke and E-Cigarette Vapors to 3-D cell cultures at the Air/Liquid Interface 
  New Orleans - 1/1/2016
• BK channels and anti-inflammatory therapy in cystic fibrosis 
  University of Florida - 1/1/2016
• Updates in therapies of Cystic Fibrosis and adverse effects of e-cigarettes 
  University of Florida - 1/1/2016
• Vaping, Electronic Cigarettes, and Synthetic Drugs 
  Ft. Lauderdale - 1/1/2016
• Angiotensin receptor blockers reverse cystic fibrosis (CF)-related mucociliary dysfunction in vitro and in a novel CF sheep model in vivo 
  Basel, Switzerland - 1/1/2016
• Nicotine containing e-cigarette exposure induces changes in lungs and airway epithelia similar to tobacco smoke 
  University of North Carolina, Chapel Hill - 1/1/2016
• Advances in Cystic Fibrosis Care; Lessons for COPD? 
  Palm Beach VA Medical Center - 1/1/2015
• BK channels and ASL volume homeostasis in Cystic Fibrosis 
  Cystic Fibrosis Research Center, 2015; Cincinnati Children�s Hospital Medical Center, University of - 1/1/2015
• Developing Therapeutics for Disorders of Mucus and Cilia 
  Galveston, TX - 1/1/2015
• Mucociliary clearance in cystic fibrosis and COPD 
  Miami, FL - 1/1/2015
• The role of BK channels and anti-inflammatory therapy in treating mucociliary dysfunction in cystic fibrosis 
  North Carolina (UNC, Duke, NC State) - 1/1/2015
• Update on treatment of Cystic Fibrosis 
  University of Miami FL - 1/1/2015
• Diagnosis and Treatment of Nontuberculous Mycobacteria Infections 
  San Diego, CA - 1/1/2014
• Bronchiectasis� and �Cystic Fibrosis 
  Interlaken Switzerland - 1/1/2014
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Other

• Hyaluronan and airway mucosal host defense 
  Forteza R., Conner G.E., Salathe M., Science of Hyaluronan Today
  http://www.glycoforum.gr.jp/science/hyaluronan/HA25/HA25E.html
  1/1/2002
• System and interpretation errors of perfusion-pressure measurements of the lower esophageal high-pressure zone and of the analysis of the pressure records, Medical Doc... 
  Salathe M
  University of Basel, Switzerland - 1/1/1987