MatthewThomasWheelerMDPhD

Cardiology • Stanford, CA

Heart Failure & Transplantation, Cardiovascular Disease Genetics

Associate Professor of Cardiovascular Medicine at Stanford University

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Office
300 Pasteur Dr
Stanford, CA 94305
Phone+1 650-723-4000

Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Advanced Heart Failure and Transplant Cardiology, 2012 - 2013
Stanford Health Care-Sponsored Stanford UniversityFellowship, Cardiovascular Disease, 2007 - 2012
Stanford Health CarePost-Doctoral Fellowship, 2007 - 2008
Stanford Health Care-Sponsored Stanford UniversityResidency, Internal Medicine, 2005 - 2007
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 2005

Certifications & Licensure

CA State Medical License 2007 - 2026
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Study of Exercise Training in Hypertrophic Cardiomyopathy Start of enrollment: 2010 Apr 01
Completed
Not Applicable
Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM Start of enrollment: 2014 Mar 01
Completed
Phase 2
A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL) Start of enrollment: 2013 Oct 01
Completed
Not Applicable
Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy Start of enrollment: 2013 Dec 09
Completed
Phase 3
Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy Start of enrollment: 2015 Feb 05
Terminated
Phase 2, Phase 3
International Consortium for Multimodality Phenotyping in Adults With Non-compaction Start of enrollment: 2021 Jan 01
Recruiting
Roles: Contact
A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy Start of enrollment: 2022 Dec 14
Active, not recruiting
Phase 3
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network Start of enrollment: 2015 Sep 16
Recruiting
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive HCM) Start of enrollment: 2022 Aug 16
Recruiting
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Publications & Presentations

PubMed

Researcher views on returning results from multi-omics data to research participants: insights from The Molecular Transducers of Physical Activity Consortium (MoTrPAC)...
Kelly E Ormond, Caroline Stanclift, Chloe M Reuter, Jennefer N Carter, Kathleen E Murphy
BMC Medical Ethics. 2025-02-07
1 citations
Reference equations for peak oxygen uptake for treadmill cardiopulmonary exercise tests based on the NHANES lean body mass equations, a FRIEND registry study.
Everton J Santana, Daniel Seung Kim, Jeffrey W Christle, Nicholas Cauwenberghs, Bettia E Celestin
European Journal of Preventive Cardiology. 2025-02-07
Unlocking insights: Clinical associations from the largest 6-minute walk test collection via the my Heart Counts Cardiovascular Health Study, a fully digital smartphon...
Daniel Seung Kim, Narayan Schuetz, Anders Johnson, Alexander Tolas, Sriya Mantena
Progress in Cardiovascular Diseases. 2025-01-28

Journal Articles

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease
Carlos A Bacino, Vandana Shashi, Euan A Ashley, Cynthia J Tifft, William A Gahl, Brendan H Lee, John J Mulvihill, Rizwan Hamid, Matthew T Wheeler, Jonathan A Bernstein..., The New England Journal of Medicine
Original Investigation Editorial Comment Genome Sequencing in Hypertrophic Cardiomyopathy∗
Euan A Ashley, Matthew T Wheeler, Chloe M Reuter, ScienceDirect

Press Mentions

Intellia, with First Results, Delivers a 'Landmark' for CRISPR Gene EditingJune 26th, 2021
Fitness Trackers Accurately Measure Heart Rate but Not Calories BurnedMay 24th, 2017
DCM Precision Medicine StudyJanuary 31st, 2017

Grant Support

GREGoR Stanford SiteNHGRI2021–Present
Center for Undiagnosed Diseases at Stanford U01NINDS2014–Present

Professional Memberships

American Heart Association - AHA
Member
American Society of Human Genetics
Member

External Links

Stanford Center for Inherited Cardiovascular Diseasehttp://familyheart.stanford.edu/
Stanford Amyloid Centerhttp://stanfordhealthcare.org/medical-clinics/amyloid-center.html
Stanford Program in Mechanical Circulatory Supporthttps://stanfordhealthcare.org/programs-services/mechanical-circulatory-support.html