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Matlock Jeffries, MD, Rheumatology, Oklahoma City, OK

MatlockJeffriesMD

Rheumatology Oklahoma City, OK

Osteoarthritis

Associate Professor, Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation

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  • Office

    825 NE 13th St.
    Oklahoma City, OK 73104
    Phone+1 405-271-7805
    Fax+1 405-271-8797

Education & Training

  • University of Oklahoma Health Sciences Center
    University of Oklahoma Health Sciences CenterFellowship, Rheumatology, 2014 - 2016
  • University of Oklahoma Health Sciences Center
    University of Oklahoma Health Sciences CenterChief Residency, Internal Medicine, 2013 - 2014
  • University of Oklahoma Health Sciences Center
    University of Oklahoma Health Sciences CenterResidency, Internal Medicine, 2010 - 2013
  • University of Oklahoma College of Medicine
    University of Oklahoma College of MedicineClass of 2010
  • University of Oklahoma
    University of OklahomaB.S., Biochemistry; Minors in Spanish, Business, Medical Humanities, 2002 - 2005
  • Oklahoma State University
    Oklahoma State UniversityBachelor's, Biochemistry; Computer Science, 2000 - 2002

Certifications & Licensure

  • OK State Medical License
    OK State Medical License 2012 - 2026
  • American Board of Internal Medicine Rheumatology

Awards, Honors, & Recognition

  • Lloyd Rader Resident Award for Excellence in Clinical Practice and Medical Research University of Oklahoma Health Sciences Center, 2014
  • Winner, Oral Presentation Competition Oklahoma Skeletal Biology Symposium, 2013
  • Winner, James F. Hammarsten Award, Best Oral Research Presentation University of Oklahoma Health Sciences Center, 2012
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Publications & Presentations

PubMed

Journal Articles

  • Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage  
    Jeffries, MA, Donica M, Baker L, Stevenson M, Annand A, Humphrey MB, James JA, Sawalha AH, Arthritis and Rheumatology, 1/30/2014
  • Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse  
    Koelsch K, Webb R, Jeffries MA, Dozmorov M, Frank MB, Guthridge J, James JA, Wren J, Sawalha AH, J. Autoimmunity, 1/1/2013
  • Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients  
    Coit P, Jeffries M, Altorok N, Dozmorov MG, Koelsch KA, Wren JD, Merrill JT, McCune WJ, Sawalha AH, J Autoimmun, 1/1/2013
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Abstracts/Posters

  • Global transcriptomic profiling of osteoarthritic chondrocytes
    Jeffries MA, Multiple Locations, 2014, 1/1/2015
  • Epigenome-wide DNA methylation study of osteoarthritic subchondral bone
    Jeffries MA, American College of Rheumatology Annual Meeting, 1/1/2015
  • Jeffries MA, American Society of Human Genetics Annual Meeting; American College of Rheumatology Annual Meeting, Boston, 2013; San Diego, 2013, 1/1/2013
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Lectures

  • Epigenomics of Osteoarthritis 
    Malaga, Spain, 2014; Sun Valley, ID, 2014 - 1/1/2014
  • k-RAS, Epigenetics, and Pancreatic Cancer 
    University of Oklahoma - 1/1/2013
  •  
    Oklahoma City - 1/1/2013
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Press Mentions

  • Checkpoint Inhibitors Seem Safe in Autoimmune Disease
    Checkpoint Inhibitors Seem Safe in Autoimmune DiseaseNovember 21st, 2024
  • OMRF Receives $412,610 Grant to Study Arthritis
    OMRF Receives $412,610 Grant to Study ArthritisNovember 18th, 2024
  • Study Links Gut Health to Osteoarthritis
    Study Links Gut Health to OsteoarthritisJune 6th, 2024
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Research History

  • Principal InvestigatorMy lab studies epigenetics in osteoarthritis with a particular focus on systemic inflammatory signatures in OA.2016 - Present

Professional Memberships