MaryLouSchmidtMD

Pediatric Hematology & Oncology • Chicago, IL

Associate Professor, Pediatrics, University of Illinois College of Medicine

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Office
1740 W Taylor St
Chicago, IL 60612
Phone+1 866-660-2273

Fax+1 312-413-9484

Education & Training

Robert H. Lurie Cancer Center, Northwestern University Medical SchoolResearch Fellowship, 1989 - 1992
McGaw Medical Center of Northwestern UniversityFellowship, Pediatric Hematology/Oncology, 1988 - 1992
Children’s Memorial Hospital, Northwestern UniversityClinical Fellowship, 1988 - 1989
McGaw Medical Center of Northwestern UniversityResidency, Pediatrics, 1986 - 1988
McGaw Medical Center of Northwestern UniversityInternship, Pediatrics, 1985 - 1986
University of Louisville School of MedicineClass of 1985
Univesity of MichiganB.S., Psychology, 1977 - 1981

Certifications & Licensure

IL State Medical License 1987 - 2026
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Best Doctors in America 2011
Gold Foundation Humanism Faculty Award (national nominee) UIC College of Medicine, 2011
Class Act Award UICMC, 2007
2007 Leonard Tow/Gold Foundation Humanism Award (Faculty) UIC College of Medicine, 2007
UIC COM Faculty Mentoring Award UIC COM, 2006
Outstanding Attending Award Department of Pediatrics UIC, 2006
2006 Women in Medicine Leadership Development Award Association of American Medical Colleges, 2006
Alpha Omega Alpha Clinical Instructor Award Alpha of Illinois Chapter, University of Illinois, 2005
Class Act Award for Competence and Compassion UICMC, 2004
Fellow The Institute of Medicine of Chicago, 2003
Essentials of Clinical Medicine Course - Exceptional Faculty UIC COM, 2003
Honorary Faculty Member Alpah Omega Alpha Alpha of Illinois Chapter, University of Illinois, 1998
Clinical Science Junior Faculty Award Children's Cancer Group, 1997
First Prize for Abstract Andrew Seligson Foundation, 1996
Frank E. Trobaugh Hematology Young Investigator Midwest Blood Club, 1992
Frederick M. Kenny Award Midwest Section of the Society for Pediatric Research, 1992
Young Investigator Award American Society for Clinical Oncology, 1991
Senior Resident Teaching Award Children’s Memorial Hospital, Northwestern University, 1988
Super Doctor SuperDoctors.com
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Clinical Trials

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET Start of enrollment: 2007 Mar 26
Active, not recruiting
Phase 3
Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma Start of enrollment: 2007 Oct 08
Completed
Phase 3
Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Start of enrollment: 2008 Feb 04
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Start of enrollment: 2010 Nov 22
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor Start of enrollment: 2011 Aug 01
Completed
Phase 2
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Start of enrollment: 2013 Feb 12
Completed
Phase 2
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma Start of enrollment: 2013 Nov 13
Completed
Phase 2
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Start of enrollment: 2014 Jul 11
Active, not recruiting
Phase 2, Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
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Publications & Presentations

PubMed

Evaluation of Image-Defined Risk Factor (IDRF) Assessment in Patients With Intermediate-risk Neuroblastoma: A Report From the Children's Oncology Group Study ANBL0531.
Erin G Brown, E Stanton Adkins, Peter Mattei, Fredric A Hoffer, Sandra L Wootton-Gorges
Journal of Pediatric Surgery. 2025-01-01
1 citations
Outcomes of patients with intermediate-risk neuroblastoma presenting with motor deficits relating to intraspinal tumor extension: A report from the Children's Oncology...
Julie Voeller, Howard M Katzenstein, Arlene Naranjo, Sheena C Tenney, Lulu Chen
Pediatric Blood & Cancer. 2025-01-01
Fibrin-associated diffuse large B-cell lymphoma in a pediatric patient.
Paige Reilly, Carlos Murga-Zamalloa, Batool H Husain, Alex Javois, Peter Varga
Pediatric Blood & Cancer. 2024-09-01

Journal Articles

Ototoxicity in Children with High Risk Neuroblastoma-Prevalence, Risk Factors and Concordance of Grading Scales: A Report from the Children’s Oncology Group.
Landier W, Knight K, Wong L, Lee J, Thomas O, Kiim H, Kreissman S, Schmidt ML, Chen L, London W, Gurney J, Bhatia S, Journal of Clinical Oncology, 5/1/2013
A Prospective Study of Expectant Observation as Primary Therapy for Neuroblastoma in Young Infants: A Children’s Oncology Group Study.
Nuchtern JG, London WB, Barnewolt CE, Naranjo A, McGrady PW, Geiger JD, Diller L, Schmidt ML, Maris JM, Cohn SL, Shamberger RC, Annals of Surgery, 10/1/2012
Outcome After Surgery Alone or With Restricted Use of Chemotherapy for Patients with Low-Risk Neuroblastoma: Results of Children’s Oncology Group Study P9641.
Strother DR, London WB, Schmidt ML, Brodeur GM, Shimada H, Thorner P, Collins MH, Tagge E, Adkins S, Reynolds CP, Murray K, Lavey RS, Matthay KK, Castleberry R, Maris..., Journal of Clinical Oncology, 4/23/2012
Prognostic value of the Stage 4S Metastatic Pattern and Tumor Biology in Patients with Metastatic Neuroblastoma diagnosed between birth and 18 months.
Taggart DR, London WB, Schmidt ML, DuBois SG, Monclair T, Nakagawara A, De Bernardi B, Ambros PF, Pearson AD, Cohn SL, Matthay KK, Journal of Clinical Oncology, 11/1/2011
Ototoxicity in childrens with high-risk neuroblastoma: Prevalence, risk factors, and concordance of grading scales-A report from the Children’s Oncology Group.
Landier W, Knight KR, Wong FL, Lee JK, Thomas O, Kim H, Kreissman SG, Schmidt ML, Chen L, London WB, Bhatia S, Gurney JG, J Clin Oncol, 1/1/2011
Biologically-based therapy reduction for intermediate-risk neuroblastoma: Children’s Oncology Group Study A3961.
Baker DL, Schmidt ML, Cohn SL, Maris JM, London WB, Buxton A, Stram D, Castleberry RP, Shimada H, Sandler A, Shamberger RC, Look AT, Seeger RC, Matthay KM, New England Journal of Medicine, 9/30/2010
Medical radiation exposure and risk of retinoblastoma resulting from new germline RB1 mutation
Bunin GR, Felice MA, Davidson W, Friedman DL, Shields CL, Maidment A, O’Shea M, Nichols KE, Leahey A, Dunkel IJ, Jubran R, Rodriguez-Galindo C, Schmidt M, Weinstein JL..., Int J Cancer, 7/20/2010
Conjunctival Marginal Zone B-cell Lymphoma in a 13 year old: a Treatment Dilemma.
Frankel, S, Gaitonde AA, Azar N, Wood MG, Schmidt ML, Journal of Pediatric Ophthalmology Strabismus, 2/1/2010
Control of disseminated intravascular coagulation in Klippel-Trenauney-Weber syndrome using enoxaparin and recombinant activated factor VIIa: a case report.
Beier UH, Schmidt ML, Hast H, Valentino LA, Journal of Medical Case Reports, 1/1/2010
Online Ethics Discussion Forum Facilitates Medical Center Clinical Ethics Case Reviews.
Ramsey DJ, Schmidt ML, Anderson-Shaw L, Journal of Nursing Administration’s Healthcare Law, Ethics and Regulation, 1/1/2010
Prolonged Chronic Phase of Chronic Myeloid Leukemia in a Patient with Congenital Human Immunodeficiency Virus Infection.
Setty, BA, Hayani KC, Sharon BI, Schmidt ML, Pediatric Blood and Cancer, 6/1/2009
Pediatric Squamous Cell Carcinoma Arising in an Alpha-Fetoprotein-Producing Mature Cystic Teratoma of the Mandible.
Cabay RJ, Setty S, Schwartz JL, Yao M, Schmidt ML, Gordon SC, Pediatric Blood and Cancer, 1/1/2008
Fixing the System not the Women: an innovative approach to faculty advancement.
Morrissey CS, Schmidt ML, Journal of Women’s Health, 1/1/2008
Pediatric Squamous Cell Carcinoma Arising in an Alpha-Fetoprotein (AFP)-Producing Cystic Teratoma of the Mandible.
Cabay R, Setty S, Schwartz JL, Yao M, Schmidt ML, Goodon SC, Arch Path Lab Med, 9/1/2007
Hearing Loss, Quality of Life and Academic Problems in Long-Term Neuroblastoma Survivors-A Report From the Children’s Oncology Group.
Gurney JG, Tersak JM, Ness KK, Landier W, Matthay KK, Schmidt ML, Pediatrics, 1/1/2007
Do Parents Have the Right to Refuse Standard Treatment for their child with Favorable Prognosis Cancer?-Ethical and Legal Concerns.
Hord JD, Rehman W, Hannon P, Anderson-Shaw L, Schmidt ML, Journal of Clinical Oncology, 12/1/2006
A novel MLL-SEPT6 fusion transcript in an infant with acute myeloid leukemia.
Kadkol SS, Bruno A, Oh S, Schmidt ML, Lundgren V, Cancer Genetics and Cytogenetics, 1/1/2006
The Role of Age in Neuroblastoma Risk Stratification: The German, Italian and Children’s Oncology Group Perspectives.
London WB, Boni L, Simon T, Berthold F, Twist C, Schmidt ML, Castleberry RP, Matthay KK, Cohn SL, De Bernardi B, Cancer Letters, 1/1/2005
Evolution of a living donor liver transplantation advocacy program.
Anderson-Shaw L, Testa G, Schmidt ML, Elkin J, Chamberlin WM, Benedetti E, The Journal of Clinical Ethics, 1/1/2005
Favorable Prognosis For Patients Ages 12-18 Months with Stage 4 MYCN-Nonamplified Neuroblastoma: A Children’s Cancer Group Study.
Schmidt ML, Lal, A, Seeger RC, Maris J, Shimada H, O’Leary M, Gerbing R, Matthay KK, J. Clin. Oncol, 1/1/2005
Differential Expression in an Antisense-MYCN Neuroblastoma (NB) Model.
Schmidt ML, Lal A, Dittmann D, Med Pediatr Oncol, 1/1/2000
Synergy between 5’ and 3’ flanking regions of the human tryosine hydroxylase gene ensures specific, high-level expression in neuroblastoma cells.
Gardaneh M, Gilbert J, Haber M, Norris MD, Cohn SL, Schmidt ML, Marshall GM, Neuroscience Letters, 1/1/2000
Biologic Factors Determine Prognosis in Infants with Stage IV Neuroblastoma: A Prospective Children’s Cancer Group Study.
Schmidt ML, Lukens J, Seeger RC, Brodeur GM, Shimada H, Gerbing RB, Stram DO, Perez C, Haase GM, Matthay KK, Journal of Clinical Oncology, 1/1/2000
Hepatoblastoma Following Renal Transplantation in a Child with Urinary Tract Anomolies.
Amin S, John E, Benedetti E, Radhakrishnan J, Ferrer K, Schey W, Schmidt ML, Journal of Pediatric Hematology/Oncology, 8/1/1999
p53 Influences Betulinic Acid-induced Apoptosis in Neuroblastoma.
Schmidt ML, Ling-Indeck L, Journal of Pediatric Hematology/Oncology, 8/1/1999
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Books/Book Chapters

In This Side of Doctoring, Reflections from Women in Medicine.
Chapter: Finding the balance point between overdrive and the mommy track.
Page 205 - 207Schmidt MLEditors: Eliza Chin.Sage Publications, Thousand Oaks, CAA2001
In This Side of Doctoring, Reflections from Women in Medicine.
Chapter: Can it be done?
Page 276 - 280Schmidt MLEditors: Eliza Chin.Sage Publications, Thousand Oaks, CAA2001

Abstracts/Posters

Data-driven Policy Recommendations to Promote the Advancement & Retention of Female Physician, Physician Scientists in the Academic Medicine Pipeline.
Kwan JM, Daye D, Schmidt ML, Morrissey C, Kim H, Payne A, Quinn K, American Association of Medical Colleges Annual Meeting (Nov 2-7, 2012), 11/2/2012
Outcome Analysis of Non-High Risk Neuroblastoma Patients Enrolled on Children’s Oncology Group Trials P9641 and A3961.
Attiyeh E, , Meany H, Naranjo A, Twist C, London W, Villablanca J, Baker D, Strother DR, Schmidt ML, Maris J, Park J, The Advances in Neuroblastoma Research Conference 2012, Toronto, Ont, Canada, 6/21/2012
Infant Metastatic (4+4S) Non-amplified Neuroblastoma has a very high survival rate with moderate dose chemotherapy.
Schmidt ML, Strother D, Baker D, Naranjo A, McGrady P, London W, Shimada H, Cohn SL, Matthay KK, Maris J, The Advances in Neuroblastoma Research Conference 2012, Toronto, Ont, Canada (Jun 18-21, 2012), 6/18/2012
Morbidity and Mortality risks in infants with Stage 4S neuroblastoma: A report from the Children’s Oncology Group study ANBL0531, “Response and Biology-based Therapy ...
Twist C, London W, Schmidt ML, Cohn SL, Park JR, Maris J, The Advances in Neuroblastoma Research Conference 2012, Toronto, Ont, Canada (Jun 18-21, 2012), 6/18/12
Outcome analysis of non-high-risk neuroblastoma patients enrolledon Children’s Oncology Group trials P9641 and A3961.
Meany HJ, Attiyeh EF, Naranjo A, Twist C, London WB, Villablanca J, Schmidt ML, Baker D, Strother DR, Shimada H, Matthay KK, Cohn SL, Maris JM, Park JR, American Society of Clinical Oncology, Chicago, IL, 6/1/2012
Caring for Children with Neuroblastoma: Biology Determines Survival.
Schmidt ML, Cancer Cell Signaling Program, UIC Cancer Center, 11/15/2011
Ototoxicity in childrens with high-risk neuroblastoma: Prevalence, risk factors, and concordance of grading scales-A report from the Children’s Oncology Group.
Landier W, Knight KR, Wong FL, Lee JK, Thomas O, Kim H, Kreissman SG, Schmidt ML, Chen L, London WB, Bhatia S, Gurney JG, American Society of Clinical Oncology Meeting Chicago, IL, 6/1/2011
Capillary Hemangiomas treated with Propranolol: A new and exciting innovation in care.
Schmidt ML, UIC Department of Pediatrics Grand Rounds, 7/16/2010
Outcome for Stage 3 Neuroblastoma: A Report From The Children’s Oncology Group.
Park JR, London WB, Schmidt ML, Baker D, Kreissman S, Villablanca JG, Shimada H, Attiyeh E, Hogarty M, Maris JH, Matthay KK, Cohn SL, Advances in Neuroblastoma Research, Sweden, 6/1/2010
Giving Bad News: Impact on Child Life Therapists.
Schmidt ML, Chicagoland Child Life Therapy Association, 5/13/2010
Panel Discussion on Sub-Specialties in Pediatrics
Schmidt ML, Pediatric Interest Group, UIC, 3/17/2010
New Approaches to Capillary Hemangiomas.
Schmidt ML, Illinois Association of Ophthalmology, Rosemont, IL, 2/19/2010
Pediatric Oncology: Life, Death and The Role of Spiritual Support
Schmidt ML, Integritas Institute for Ethics, UIC, 2/11/2010
107. Why I love being a Physician in the 21st Century.
Schmidt ML, Society of Future Physicians, UIC, 10/20/2009
Significance of tumor biology compared to metastatic pattern (INSS 4 vs 4s) and age for prognosis of neuroblastoma less than 18 months of age.
Taggert, D, London W, Schmidt, ML, Zhang Y, DuBois S, Monclair T, Pearson A, Cohn SL, Matthay KK, American Society of Clinical Oncology Meeting, Orlando, FL, 6/1/2009
Women and Medicine Panel and Discussion: “Life in the Fast Lane: Insights from the Journeys of Women Physician Scientists”.
Schmidt ML, American Physician Scientist Association, Chicago, IL, 4/24/2009
Faith at the bedside for patients with life-threatening conditions.
Schmidt ML, UIC Catholic Medical Student Association, 3/26/2009
Disclosure of Poor Prognosis to a 13 y/o with multiply relapsed cancer.
Schmidt ML, Jewish Medical Ethics Symposium, UIC, 3/18/2009
Lifestyle Panel
Schmidt ML, American Medical Women’s Association Region 6 Conference and Research Symposium, UIC, Chicago, IL, 1/18/2009
Fixing the System, Not the Women
Schmidt ML, American Medical Women’s Association Region 6 Conference and Research Symposium, UIC, Chicago, IL, 1/17/2009
Seeking Nirvana: Finding Balance between Personal and Professional Goals.
Schmidt ML, Kwan J, UIC Undergraduate Honors Seminar, 11/19/2008
Pediatric Oncology Research: The Impact of Collaborative Clinical Trials
Schmidt ML, Partnerships 4 Cure Donors Forum, Chicago, IL, 5/15/2008
Genomic Aberration Patterns Predict Relapse in Low- And Intermediate-Risk Neuroblastoma (NB): A Children’s Oncology Group (COG) Study
Advances in Neuroblastoma Research meeting, Japan, 5/1/2008
A Career in Pediatric Oncology
Schmidt ML, Hematology/Oncology Interest Group, UIC COM, 4/17/2008
Parity without Power, Chicago Medical Student Campus Leadership Series.
Schmidt ML, Chicago Medical Student Campus Leadership Series, 3/25/2008
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