Dr. Patti is on Doximity
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Office
1 Joslin Pl
# Joslin
Boston, MA 02215Phone+1 617-735-1966Fax+1 617-309-2593
Summary
- Dr. Patti is a physician-scientist, serving as Principal Investigator at Joslin Diabetes Center, Director of the Hypoglycemia Clinic, Co-Director of the Molecular Phenotyping Core, and Associate Professor of Medicine at Harvard Medical School. Dr. Patti’s NIH-funded lab focuses on identification of molecular/epigenetic mechanisms by which nutritional exposures during early life increase diabetes risk in subsequent generations. Translational studies are focused on mechanisms contributing to diabetes resolution and hypoglycemia after bariatric surgery. Dr. Patti received her MD from Jefferson Medical College magna cum laude, with internal medicine residency at University of Pittsburgh, and endocrinology fellowship at Harvard.
Education & Training
- Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 1992 - 1995
- UPMC Medical EducationResidency, Internal Medicine, 1985 - 1988
- Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1985
Certifications & Licensure
- MA State Medical License 1992 - 2025
- PA State Medical License 1986 - 1992
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- Fellow American College of Physicians, 2014
- Fellow Obesity Society, 2013
- CMS Meaningful Use Stage 1 Certification NextGen Ambulatory EHR, NextGen Healthcare, 2011-2012
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Clinical Trials
- Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia Start of enrollment: 2017 Sep 19
- Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety After Gastric Surgery Start of enrollment: 2019 Feb 07
- Hypoglycemia and the Gut Microbiome Start of enrollment: 2019 Feb 07
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Publications & Presentations
PubMed
- 34 citationsMicroneedle Aptamer-Based Sensors for Continuous, Real-Time Therapeutic Drug Monitoring.Yao Wu, Farshad Tehrani, Hazhir Teymourian, John Mack, Alexander Shaver
Analytical Chemistry. 2022-06-14 - 793 citationsInsulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle.Kenneth Cusi, Katsumi Maezono, Abdullah A. Osman, Merri Pendergrass, Mary-Elizabeth Patti
The Journal of Clinical Investigation. 2000-02-01 - 445 citationsSerum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid MetabolismMary-Elizabeth Patti, Sander M. Houten, Antonio C. Bianco, Raquel Bernier, P. Reed Larsen
Obesity. 2009-09-01
Lectures
- Evaluation and Treatment of Post-Bariatric Surgery HypoglycemiaENDO 2018: 100th Endocrine Society Annual Meeting - Chicago, Illinios - 03/18/2018
- Bariatric Surgery: Remodeling the Next GenerationENDO 2018: 100th Endocrine Society Annual Meeting - Chicago, Illinios - 03/17/2018
- American Diabetes Association (ADA) 73rd Scientific Sessions 2013American Diabetes Association, Chicago, Illinois - 6/21/2013
Press Mentions
- Continuous Glucose Monitoring Might Help in Managing Postoperative HypoglycemiaJuly 28th, 2023
- Glucagon Delivery System Treats Post-Bariatric HypoglycemiaJanuary 30th, 2020
- New Closed-Loop System Offers Promise as Novel Treatment for Post-Bariatric HypoglycemiaJanuary 9th, 2020
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Grant Support
- Genomics CoreNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2011
- Gene Expression In Prediabetes: Potential Role Of PGC-1National Institute Of Diabetes And Digestive And Kidney Diseases2003–2006
- Core--GenomicsNational Institute Of Diabetes And Digestive And Kidney Diseases2002
- Mechanisms Of Ffa-Induced Hepatic Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2001
- Bifunctional Modulation Of Insulin Action By Amino AcidsNational Institute Of Diabetes And Digestive And Kidney Diseases1997–2001
Committees
- Chair, American Diabetes Association Scientific Sessions Planning Committee 2011 - 2013
Professional Memberships
- Member
- Member
- Member
- Member
- Fellow
- Fellow
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