MarlenePFreemanMD

Professor of Psychiatry, Harvard Medical School; Assoc Director, Center for Women's Mental Health; Clinical Trials Network & Institute; Massachusetts General Hospital. Editor-in-Chief, The Journal of Clinical Psychiatry

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Office
15 Parkman St
Boston, MA 02114
Phone+1 617-724-5600

Fax+1 617-643-3080

Education & Training

University of Cincinnati Medical CenterFellowship, 1998 - 1999
Brigham and Women's Hospital/Harvard Medical SchoolResidency, Psychiatry, 1994 - 1998
Northwestern University The Feinberg School of MedicineClass of 1994
University of WisconsinBS, Zoology, 1986 - 1990

Certifications & Licensure

MA State Medical License 1996 - 2026
AZ State Medical License 2000 - 2009
TX State Medical License 2007 - 2008
OH State Medical License 1998 - 2001
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

Use of Omega-3 Fatty Acids for Perinatal Depression Start of enrollment: 2004 Jun 01
Completed
Phase 2
Omega-3 for Peri- and Postmenopausal Depression Start of enrollment: 2008 Nov 01
Completed
Not Applicable
Escitalopram (Lexapro) for the Treatment of Postpartum Depression Start of enrollment: 2009 Jan 01
Completed
Phase 4
Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia Start of enrollment: 2009 Jul 01
Completed
Phase 4
Duloxetine for Menopausal Depression Start of enrollment: 2009 Aug 01
Completed
Phase 4
Trial of Low Field Magnetic Stimulation Augmentation of Antidepressant Therapy in Treatment-Resistant Depression Start of enrollment: 2013 Apr 01
Completed
Not Applicable
Symptom Tracking in Assisted Reproductive Technologies Start of enrollment: 2012 Oct 01
Completed
Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD) Start of enrollment: 2014 Dec 01
Completed
Phase 2
Vortioxetine for Menopausal Depression Start of enrollment: 2015 Jun 12
Completed
Phase 4
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy Start of enrollment: 2017 Jan 24
Completed
Not Applicable
Preconception and Pregnancy Obesity Treatment and Prevention Among Women With a History of Depression Start of enrollment: 2017 Feb 17
Recruiting
Not Applicable
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression Start of enrollment: 2018 Sep 01
Recruiting
Phase 1, Phase 2
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Publications & Presentations

PubMed

The phenomenology of postpartum psychosis: preliminary findings from the Massachusetts General Hospital Postpartum Psychosis Project.
Lee S Cohen, Miranda Arakelian, Taylor R Church, Madison M Dunk, Margaret L Gaw
Molecular Psychiatry. 2024-12-06
1 citations
The Risk of Postpartum Hemorrhage with Selective Serotonin Reuptake Inhibitors and Serotonin Norepinephrine Reuptake Inhibitors: Preliminary Results from the Massachus...
Adele C Viguera, Alexia Jones, Mercedes J Szpunar, Sarah N Bernstein, Parker C Killenberg
Journal of Women's Health. 2024-12-01
Reproductive Pharmacovigilance and Best Practices.
Marlene P Freeman
The Journal of Clinical Psychiatry. 2024-08-26

Journal Articles

Research Paper Tachyphylaxis in Major Depressive Disorder: A Review of the Current State of Research
Gustavo Kinrys, Andrew A Nierenberg, George I Papakostas, David Mischoulon, Maurizio Fava, Marlene P Freeman, ScienceDirect
Double-Blind, Placebo-Controlled, Dose-Ranging Trial of Intravenous Ketamine as Adjunctive Therapy in Treatment-Resistant Depression (TRD)
Sanjay J Mathew, Madhukar H Trivedi, Lee C Chang, Dan V Iosifescu, Manish K Jha, Maurizio Fava, Marlene P Freeman, Cristina Cusin, James Murrough, George I Papakostas,..., Nature
Course of Major Depressive Disorder After Pregnancy and the Postpartum Period
Lee S Cohen, Vivien K Burt, Marlene P Freeman, Danna Moustafa, Depression and Anxiety

Press Mentions

No Protection Against Relapse with CBT Added to Maintenance AntidepressantsDecember 3rd, 2019
Register Online MGH Conference on Women’s Mental Health – October 17, 2019September 11th, 2019
Sage’s Zulresso for Postpartum Depression Has Uncertain Payer CoverageJuly 19th, 2019
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Grant Support

A neurosteroid intervention for menopausal and perimenopausal depressionNational Institute on Aging (NIA), NIH, R01 mechanism2018–2023
Postpartum Depression: Omega-3 FA VS PlaceboNational Institute Of Mental Health2002–2006

Professional Memberships

American Society of Clinical Psychopharmacology
Board of Directors
American College of Neuropsychopharmacology
Member
Postpartum Support International
Member