MarlanaMariaOrloffMD

Oncology • Philadelphia, PA

Hematologic Oncology, Melanoma

Assistant Professor

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Office
925 Chestnut St
Ste 320A
Philadelphia, PA 19107
Phone+1 215-955-1175

Fax+1 215-955-2340

Education & Training

Sidney Kimmel Medical College at Thomas Jefferson University/TJUHFellowship, Hematology and Medical Oncology, 2012 - 2015
Sidney Kimmel Medical College at Thomas Jefferson University/TJUHResidency, Internal Medicine, 2009 - 2012
Pennsylvania State University College of MedicineClass of 2009

Certifications & Licensure

DE State Medical License 2017 - 2025
NJ State Medical License 2017 - 2025
PA State Medical License 2009 - 2024
American Board of Internal Medicine Medical Oncology

Clinical Trials

Ipilimumab and Nivolumab With Immunoembolization in Treating Participants With Metastatic Uveal Melanoma in the Liver Start of enrollment: 2018 May 02
Active, not recruiting
Phase 2
A Prospective Natural History Study in Uveal Melanoma Start of enrollment: 2021 May 06
Recruiting
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions Start of enrollment: 2019 Jun 28
Recruiting
Phase 1, Phase 2
Roles: Contact
Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma Start of enrollment: 2021 Aug 02
Active, not recruiting
Phase 1
Roles: Contact, Principal Investigator
IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma Start of enrollment: 2023 Oct 31
Recruiting
Phase 2, Phase 3
Roles: Contact
(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma Start of enrollment: 2023 Jul 03
Recruiting
Phase 2
Roles: Contact
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Publications & Presentations

PubMed

Treatment sequence with tebentafusp and immune checkpoint inhibitors in patients with metastatic uveal melanoma and metastatic GNA11/GNAQ mutant melanocytic tumors.
Florentia Dimitriou, Marlana M Orloff, Erica C Koch Hein, Phil F Cheng, Isaac F Hughes
European Journal of Cancer. 2025-01-01
Correction: Efficacy and Safety of the Melphalan/Hepatic Delivery System in Patients with Unresectable Metastatic Uveal Melanoma: Results from an Open-Label, Single-Ar...
Jonathan S Zager, Marlana Orloff, Pier Francesco Ferrucci, Junsung Choi, David J Eschelman
Annals of Surgical Oncology. 2024-11-01
Meeting Report From the 2023 Cure Ocular Melanoma (CURE OM) Global Science Meeting, Philadelphia, PA, November 2023.
Rino S Seedor, Andrew E Aplin, Corine Bertolotto, Richard D Carvajal, Nigel Deacon
Pigment Cell & Melanoma Research. 2024-10-09

Press Mentions

TriSalus Life Sciences Expands Clinical Executive Team and Scientific Advisors in Support of Company’s Focus to Overcome Liver and Pancreatic Cancer Treatment Barriers and Enable More Patients to Benefit from ImmunotherapyFebruary 10th, 2022
Metastatic Uveal Melanoma: New Drugs in Pipeline, but Prognoses Remain GrimDecember 14th, 2021
TriSalus Life Sciences Announces First Patient Enrolled in PERIO-01 Clinical Trial to Evaluate Delivery of SD-101 via Pressure-Enabled Drug Delivery in Uveal Melanoma Liver MetastasesSeptember 7th, 2021
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External Links

Jefferson Linkhttp://hospitals.jefferson.edu/find-a-doctor/o/orloff-marlana-m/