MarkusYMaparaMDPhD

PubMed

• 495 citations
  CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.
  Haydar Frangoul, David Altshuler, M Domenica Cappellini, Yi-Shan Chen, Jennifer Domm
  The New England Journal of Medicine. 2021-01-21
• 52 citations
  Phase 1a/b Study of Monoclonal Antibody CAEL-101 (11-1F4) in Patients with AL Amyloidosis
  Camille V Edwards, Nisha Rao, Divaya Bhutani, Markus Y. Mapara, Jai Radhakrishnan
  Blood. 2021-09-14
• 164 citations
  Time-intensified dexamethasone/cisplatin/cytarabine:an effective salvage therapy with low toxicity in patients with relapsed and refractory Hodgkin’s disease
  Andreas Josting, Christian Rudolph, Marcel Reiser, Markus Y. Mapara, M. Sieber
  Annals of Oncology. 2002-10-01

Journal Articles

• Immunomodulatory Drugs Downregulate IKZF1 Leading to Expansion of Hematopoietic Progenitors with Concomitant Block of Megakaryocytic Maturation  
  Markus Y Mapara, Sara A Monaghan, Suzanne Lentzsch, Haematologica
• Brentuximab Vedotin and Bendamustine Produce High Complete Response Rates in Patients with Chemotherapy Refractory Hodgkin Lymphoma  
  Changchun Deng, Markus Y. Mapara, Ahmed Sawas, Matko Kalac, British Journal of Haematology

Abstracts/Posters

• Combination Chemotherapy with Carfilzomib, Bendamustine and Dexamethasone Is Highly Active for Therapy of Newly Diagnosed Multiple Myeloma-Results of Single Center Pha...
  Markus Y. Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Excellent Survival and Immune Reconstitution Following Matched/Mismatched Unrelated and Mismatched Related Transplantation in Adult Patients with Sickle Cell Disease: ...
  Markus Y Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Exploring the Drivers of Potential Clinical Benefit in Initial Patients Treated in the Hgb-206 Study of Lentiglobin for Sickle Cell Disease (SCD) Gene Therapy
  Markus Y. Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Resolution of Sickle Cell Disease Manifestations in Patients Treated with Lentiglobin Gene Therapy: Updated Results from the Phase 1/2 Hgb-206 Group C Study
  Markus Y. Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Autologous Transplant Recipients Have a Healthier Gut Microbiota at Baseline and Faster Recovery from Microbiome Injury Compared to Allogeneic Transplant Recipients
  Markus Y. Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Checkpoint Inhibitor PD-1H/VISTA Functions As MMP-13 Receptor on Osteoclasts and Mediates MMP-13 Induced Osteoclast Activation in Multiple Myeloma
  Markus Y. Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Gck Kinase Activity Is Critical for RAS Mutated Myeloma - a Potential Treatment Approach for Targeting Specific Mutations
  Markus Y Mapara, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

• Outcomes for Initial Patient Cohorts with up to 33 Months of Follow-up in the Hgb-206 Phase 1 Trial 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018