MarkKSantillanMDPhD, FACOG,FAHA

Obstetrics & Gynecology • Iowa City, IA

Maternal & Fetal Medicine/High Risk

Associate Professor, University of Iowa College of Medicine

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Office
200 Hawkins Dr
Iowa City, IA 52242
Phone+1 319-356-1616

Fax+1 319-384-6004

Education & Training

University of IowaNo Degree, Translational Biomedicine, 2009
University of Iowa Carver College of MedicinePhD, Translational Biomedicine, 2009 - 2015
University of Iowa Hospitals and ClinicsFellowship, Maternal-Fetal Medicine, 2006 - 2009
University of Iowa Hospitals and ClinicsResidency, Obstetrics and Gynecology, 2002 - 2006
Loyola University Medical CenterResidency, Obstetrics and Gynecology, 2002 - 2006
Loyola University Chicago Stritch School of MedicineClass of 2002
Loyola University ChicagoB.A./B.S., Philosophy/Chemistry, 1994 - 1998

Certifications & Licensure

IA State Medical License 2006 - 2026
IL State Medical License 2002 - 2014
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Maternal-Fetal Medicine

Awards, Honors, & Recognition

Reproductive Scientist Development Program Scholar National Institutes of Health, 2011-2016
Junior Faculty Teacher of the Year M3, 2013
Best Poster Session IV Society for Maternal Fetal Medicine 33rd Annual Meeting, 2013
Vision Grant Preeclampsia Foundation, 2013
National Faculty Award for Excellence in Resident Teaching ACOG/CREOG, 2011
National Faculty Teaching Award ACOG, 2011
Reproductive Scientist Development Program Scholar 2011
KL2 Scholar Award University of Iowa Institute for Clinical and Translational Science, 2008
Institutional Research Fellowship Iowa Cardiovascular Center, 2007
Resident Teacher of the Year Loyola SSOM, 2006
Resident Teaching Award Burex, 2003
Fellow American Pediatric Society/Society for Pediatric Research, 1999
Merck Index Award 1998
Outstanding Graduating Senior American Institute of Chemists, 1998
Phi Beta Kappa 1998
Discover Pharmacology Research Fellowship Loyola 1997
Alpha Sigma Nu Jesuit Honor Society 1997
Golden Key National Honor Society 1996
Academic Scholarship Philip Morris, 1994
Presidential Scholarship Loyola University Chicago, 1994
Fellow (FACOG) American Congress of Obstetricians and Gynecologists
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Clinical Trials

Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women Start of enrollment: 2007 Sep 01
Terminated
Not Applicable
Improving Women's and Children's Health Via Biobanking and Electronic Registry Start of enrollment: 2020 Jan 07
Completed

Publications & Presentations

PubMed

Validation of the Patient-Reported Outcomes Measurement Information System Pain Intensity and Brief Pain Inventory During Pregnancy.
Julie Vignato, Yelena Perkhounkova, Hannah Marilim, Jihye Lee, Maria Hein
Western Journal of Nursing Research. 2025-02-08
Depression in the time of COVID-19: Examination of prenatal and postpartum depression, rurality, and the impact of COVID-19.
Kelsey L Blocklinger, Serena B Gumusoglu, Ashlyn S Kenney, Alexis J Faudel, Elissa Faro
Journal of Affective Disorders. 2025-02-01
1 citations
Reduced ATR Signaling Contributes to Endothelial Dysfunction After Preeclampsia.
Kelsey S Schwartz, Mingyao Sun, Diana I Jalal, Mark K Santillan, Anna E Stanhewicz
Hypertension. 2024-12-26

Journal Articles

Vasopressin in preeclampsia: a novel very early human pregnancy biomarker and clinically relevant mouse model.
Santillan MK, Santillan DA, Scroggins SM, Min JY, Sandgren JA, Pearson NA, Leslie KK, Hunter SK, Zamba GK, Gibson-Corley KN, Grobe JL., Hypertension, 10/2014
PlacentaSpecific Protein 1: A Potential Key to Many Oncofetal-Placental OB/GYN Research Questions
Devor EJ, Reyes HD, Santillan DA, Santillan MK, Onukwugha C, Goodheart MJ, Leslie KK, Obstet Gynecol Int, 1/1/2014
Collection of a Lifetime: A Practical Approach to Developing a Longitudinal Collection of Women's Healthcare Biological Samples
Santillan MK, Leslie KK, Hamilton WS, Boese BJ, Ahuja M, Hunter SK, Santillan DA, Eur J Obstet Gynecol Reprod Biol, 1/1/2014
Vasopressin in Preeclampsia: A Novel Very Early Human Pregnancy Biomarker and Clinically Relevant Mouse Model
M. Santillan, D. Santillan, S. Scroggins, J. Min, J. Sandgren, N. Pearson, K. Leslie, S. Hunter, G.Zamba K. Gibson-Corley, J. Grobe, Hypertension, 1/1/2014
Preeclampsia and microRNAs
Devor E, Santillan DA, Santillan MK, Proc Obstet Gynecol, 1/1/2013
Noninvasive Fetal Genome Sequencing: A Primer
Snyder MW, Simmons LE, Kitzman JO, Santillan DA, Santillan MK, Gammill HS, Shendure J, Prenat Diagn, 1/1/2013
Wandering Womb, Water and Worms: The History, Myths, and Messy Immunologic Etiology of Preeclampsia/eclampsia
Santillan MK, POG, 1/1/2013
Non-invasive Fetal Genome Sequencing: Opportunities and Challenges
Tabor HK, Murray J, Gammill HS, Kitzman JO, Snyder MW, Ventura M, Lewis AP, Qiu R, Simmons LE, Rubens CE, Santillan MK, Eichler EE, Cheng EY, Bamshad MJ, She..., Am J Med Genet, 1/1/2012
Anti-Mullerian Hormone Concentration Levels in Maternal Plasma during the First, Second and Third Trimester of Pregnancy
Stegmann B, Santillan MK, Santillan DA, Smith E, Van Voorhis B, Schultz K, Proc Obstet Gynecol, 1/1/2012
The Influence of Fetal Sex on Patterns of Change in Anti-Mullerian Hormone during Pregnancy
Empey R, Santillan DA, Santillan MK, Tyler E, Hunter S, Smith E, Stegmann B, Proc Obstet Gynecol, 1/1/2012
Efficacy of Polymeric Encapsulated C5a peptidase-based Group B Streptococci Vaccines in a Murine Model
Santillan DA, Rai K, Santillan MK, Krishnamachari Y, Salem AK, Hunter S, Am J Obstet Gynecol, 1/1/2011
2010 Updates of the CDC Guidelines for GBS in Pregnancy
Santillan MK, Santillan DA, The Perinatal Letter, 1/1/2010
Preeclampsia/Eclampsia: An Immediate and Long Term Problem
Santillan MK, Hunter S, The Perinatal Letter, 1/1/2008
The Effects of Preeclampsia on Signaling to Hematopoietic Progenitor Cells
Santillan DA, Hamilton W, Christenson A, Talcott K, Gravatt L, Santillan MK, Hunter S, Proc Obstet Gynecol
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Press Mentions

Daily Recap: Lung Ultrasound Helps Diagnose COVID-19 in Kids, First Treatment Approved for Adult-Onset Still’s DiseaseJune 18th, 2020
New Definitions of Hypertension Reveal New Preeclampsia RisksJune 18th, 2020
GO RED for Your Heart Health on October 24thOctober 1st, 2019
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