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Mark Pepin, MD, Internal Medicine, Boston, MA

MarkPepinMD, PhD, MS(He/Him)

Internal Medicine • Boston, MA

MD, PhD, MS | PGY1 | Brigham and Womens Hospital | Harvard Medical School | Boston, MA, USA

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  • Office

    75 Francis St
    Boston, MA 02115

Summary

  • Mark Pepin, MD, PhD is currently a resident physician at Brigham and Women's Hospital and Harvard Medical School. His clinical and scientific interests are centered in end-stage heart failure, specifically the targeted molecular and epigenetic therapies for myocardial disease. He was recently a Humboldt postdoctoral fellow at the Institute for Experimental Cardiology at Heidelberg University (Heidelberg, DE), where his main project defined a causal role of catecholaminergic histone modifications in heart failure-induced carcinogenesis.

Education & Training

  • Brigham and Women's Hospital
    Brigham and Women's HospitalResidency, Internal Medicine, 2022
  • Universitätsklinikum Heidelberg
    Universitätsklinikum HeidelbergPost-Doctoral Fellowship, 2020 - 2022
  • University of Alabama School of Medicine
    University of Alabama School of MedicineClass of 2020, MD, AOA Member
  • University of Alabama at Birmingham
    University of Alabama at BirminghamPhD, Biomedical Engineering, Suma Cum Laude, 2015 - 2019
  • UC Davis
    UC DavisMS, Biomedical Engineering, Cum Laude, 2011 - 2013
  • Clemson University
    Clemson UniversityBS, Chemical Engineering, Cum Laude, 2006 - 2011

Certifications & Licensure

  • CA State Medical License
    CA State Medical License 2024 - 2026
  • MA State Medical License
    MA State Medical License 2022 - 2024

Awards, Honors, & Recognition

  • "Tinsley Harrison" Excellence in Clinical Medicine UAB Department of Medicine, 2022
  • “William C. Stanley” Early Investigator Award Society for Heart and Vascular Metabolism, 2019
  • "Samuel B Barker" Award for Excellence in Graduate Studies UAB Graduate School, 2019
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Publications & Presentations

PubMed

Journal Articles

  • Glucagon-Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21  
    Stephen Barnes, Mark Pepin, Diabetes Care

Press Mentions

  • Race and Poverty Appear to Guide Heart Muscle DNA Methylation in Heart-Failure Patients
    Race and Poverty Appear to Guide Heart Muscle DNA Methylation in Heart-Failure PatientsApril 7th, 2021
  • Epigenetic Reprogramming of Human Hearts Found in Congestive Heart Failure
    Epigenetic Reprogramming of Human Hearts Found in Congestive Heart FailureAugust 10th, 2018
  • Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure
    Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart FailureAugust 10th, 2018
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Grant Support

  • "DZHK-Omics: Intuitive and Standardized Bulk RNA-Sequencing Analysis for the Coding-Naïve Basic Scientist."DZHK - German Society for Heart Research2021–2022
  • "The role of CaMKII-dependent histone modification in heart failure-induced carcinogenesis."Alexander von Humboldt Society2020–2022
  • Developing an Integrated Media Production Studio for Medical EducationUAB Innovations in Medical Education2018–2020
  • "Gadd45b and Metabolic Memory in Diabetic Heart Failure."NIH National Heart, Lung, and Blood Institute (NHLBI)2017–2020

Committees

  • Director, Academic Engagement Committee 2015 - 2020

Research History

  • First AuthorDoes an optimal learning style exist in preclinical medicine? A Learning Assessment and Study Skills Inventory.2016 - 2019
  • First AuthorHAART-Induced Metabolic Syndrome and Adipocyte-Infiltrating Macrophages.2016 - 2018
  • Middle-AuthorGamificaiton of medical knowledge as a retention tool for physician scientists.2017 - 2017
  • First AuthorEtiology-specific heart failure susceptibility: of mice and men.
  • First AuthorEpigenetic reprogramming of the failing diabetic heart.

Professional Memberships

Other Languages

  • German

Dr. Mark Pepin, Dr. Mark Pepin, MD, Dr. M Pepin