MarkEdwardPennesiMDPhD

PubMed

• 95 citations
  The effects of PEGylation on LNP based mRNA delivery to the eye
  Renee C. Ryals, Siddharth Patel, Chris Acosta, Madison McKinney, Mark E. Pennesi
  Plos One. 2020-10-29
• 284 citations
  Animal models of age related macular degeneration.
  Mark E. Pennesi, Martha Neuringer, Robert J. Courtney
  Molecular Aspects of Medicine. 2012-08-01
• 22 citations
  Three-Year Safety Results of SAR422459 (EIAV-ABCA4) Gene Therapy in Patients With ABCA4-Associated Stargardt Disease: An Open-Label Dose-Escalation Phase I/IIa Clinica...
  Maria A Parker, Laura R Erker, Isabelle Audo, Dongseok Choi, Saddek Mohand-Said
  American Journal of Ophthalmology. 2022-08-01

Journal Articles

• Strategies for Treating Inherited Retinal Degeneration with Large Genes That Are Not Amenable to Adeno-Associated Virus–Based Gene Replacement Therapy  
  Mark E Pennesi, Richard G Weleber, JAMA Ophthalmology
• Disease Course in Patients with Pentosan Polysulfate Sodium–Associated Maculopathy After Drug Cessation  
  Joseph M Simonett, Mark E Pennesi, Nieraj Jain, JAMA Ophthalmology
• Effect of Oral Valproic Acid vs Placebo for Vision Loss in Patients with Autosomal Dominant Retinitis Pigmentosa  
  David G Birch, Michael P Teske, Richard G Weleber, Robert Lindblad, Byron L Lam, Judith Warner, Gary Edd Fish, Neal L Sklaver, Mark E Pennesi, John Heckenlively, Paul ..., JAMA
• Preliminary Results of a New Method of Drug Delivery Into the Subretinal Space Using Antibody Conjugated Gold Nanoparticles.  
  Hayashi A, Naseri A, Pennesi ME, Lam H, de Juan E, Jr, Invest Ophthalmol Vis Sci
• GCAP1 Rescues Rod Photoreceptor Response in GCAP1/GCAP2 Knockout Mice.  
  Baehr W, Pennesi ME, Sokal I, et al, Invest Ophthalmol Vis Sci
• ERG Analysis of Cone Recovery in GCAP1/GCAP2 and GCAP2 Null Mice Using Paired Flashes.  
  Pennesi ME, Howes K, Baehr W, Wu S, Invest Ophthalmol Vis Sci
• Safety of Intravitreal Voriconazole - Histopathologic and Electoretinographic Study.  
  Gao H, Pennesi ME, Shah K, Mieler WF, Wu SM, Holz ER, Invest Ophthalmol Vis Sci
• SCA7 Knock-In Mice Reproduce the Retinal Degeneration Seen in Human SCA7.  
  Pennesi ME, Yoo S, Wu SM, Zogbhi H, Invest Ophthalmol Vis Sci
• Delayed ERG b-wave Switching off in PKC-alpha Knock Out Mice.  
  Ruether KW, Leitges M, Pennesi ME, Wu SM, Strauss ORuether KW, Leitges M, Pennesi ME, Wu SM, Strauss O, Invest Ophthalmol Vis Sci
• Altered Lacrimal Response in Protein-kinase C deficient mice.  
  Basti S, Pennesi ME, Leitges M, et al, Invest Ophthalmol Vis Sci
• Functional Studies of a human rhodopsin-EGFP fusion in knock-in mice.  
  Kyle KA, Gross AK, Rubin WW, et al, Invest Ophthalmol Vis Sci
• ERGs from Bhlhb4 knockout mice reveal normal rod-driven a-waves but severely diminished b-waves.  
  Pennesi ME, Bramblett D, Tsai M-J, Wu SM, Invest Ophthalmol Vis Sci
• Safety of Intravitreal Moxifloxacin: Electroretinographic and Histopathologic Study.  
  Gao H, Pennesi ME, Iyer M, Qiao X, Holz ER, Mieler WF, Invest Ophthalmol Vis Sci
• Relationship of Retinal Vasculature Development and Photoreceptor Degeneration in Mutant Rhodopsin Transgenic Rats.  
  Pennesi ME, Matthes MT, Yasumura D, La Vail MM, Invest Ophthalmol Vis Sci
• Genetic Dissection of Retinal Pathways Using the Electroretinogram (ERG).  
  Pennesi ME, Abd-El-Barr MM, Saszik SM, et al, Invest Ophthalmol Vis Sci
• OCT/SLO Offers a New Perspective on Retinal Disease.  
  Pennesi ME, Stewart JM, Retina Times
• Slow Insensitive Scotopic Responses in Three Children With Leber Congenital Amaurosis (LCA): A New Electroretinogram (ERG) Phenotype?  
  Pennesi ME, Weleber RG, Invest Ophthalmol Vis Sci
• Serotonin Receptor Expression in the Rodent Retina.  
  Michaels KV, Stoddard JW, Blum ED, Maricle A, Zhou E, Pennesi ME, Francis PJ, Invest Ophthalmol Vis Sci
• Handheld Spectral Domain Optical Coherence Tomography in the Evaluation of Patients with Congenital Nystagmus.  
  Courtney RJ, Wen Y, Pickell SR, Weleber RG, Pennesi ME, Invest Ophthalmol Vis Sci
• Characterization of Retinal Degeneration in rd1 and rd10 Mice Using Spectral Domain OCT.  
  Pennesi ME, Magee SS, Garg AK, Tu DC, Wen Y, Maricle A, Invest Ophthalmol Vis Sci
• Lentiviral Vector Gene Replacement Therapy in Stargardt Disease and Usher Syndrome Type 1b.  
  Stout JT, Wilson DJ, Weleber RG, Pennesi ME, Toomey M, Francis P, Sahel JA, Audo I, Mohand-Said S, Naylor SM, Invest Ophthalmol Vis Sci
• Measuring the Performance of an Adaptive Optics Flood Illuminated Camera for Imaging the Cone Mosaic in a Clinical Setting.  
  Fay JD, Faridi A, Garg AK, Pennesi ME, Invest Ophthalmol Vis Sci
• Expression and Localzation of Serotonin Receptors in the Mouse Retina.  
  Pennesi ME, Stoddard JW, Michaels KV, Blum ED, Maricle A, Francis PJ, Invest Ophthalmol Vis Sci
• Slow Insensitive Scotopic Responses in Leber Congenital Amaurosis Patients with AIPL1 mutations. Investigative Ophthalmology and Visual Sciences.  
  Pennesi ME, Stover NB, Stone EM, Chiang PW, Weleber RG, Invest Ophthalmol.Vis.Sci
• Retinal Degenerations Associated with Systemic Diseases.  
  Courtney RJ, Pennesi ME, International Ophthalmology Clinics
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Books/Book Chapters

• Online Encyclopedia of the Eye 
  Chapter: Primary Photoreceptor Degenerations: Terminology 
  Pennesi ME, Francis PJ, Weleber RGEditors: Bok D, Besharse, J.C.
• Online Encyclopedia of the Eye. 
  Chapter: Primary Photoreceptor Degenerations: Retinitis Pigmentosa 
  Pennesi ME, Francis PJ, Weleber RGEditors: Bok D, Besharse, J.C.
• Genetic Diseases of the Eye. 
  Chapter: Peroxisomal Disorders 
  Pennesi ME and Weleber RGEditors: Traboulsi E.
• Retina. 
  Chapter: Retinitis Pigmentosa 
  Gregory-Evans KA, Pennesi ME, Weleber RGEditors: Ryan SJ.Edition 5,
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Abstracts/Posters

• Lentiviral Vector for Gene Replacement Therapy in Stargardt Disease and Usher Syndrome Type IB.
  Wilson D, Stout JT, Weleber RG, Pennesi ME, Francis PJ, Sahel J, Mohand-Said S, Naylor S Audo I, Macula Society, Jerusalem Israel
• Imaging the Cone Mosaic using a Commerically available Adaptive Optics Flood Illuminated Camera and Examining its Potential as an Endpoint for Clinical Trials.
  Pennesi ME, Fay JD, Faridi A, Garg AK, Chegarnov EN, Michaels KV, International Society for Clinical Electrophysiology in Vision, Valencia, Spain
• Hand-Held Spectral-Domain Optical Coherence Tomography in the Evaluation of Patients in a Pediatric Ophthalmic Genetics Clinic.
  Pennesi ME, Courtney RJ, Francis PJ, Weleber RG, International Society for Clinical Electrophysiology in Vision, Quebec City, Montreal
• Results from 12 years of experience with propofol for sedated ERGs.
  Pennesi ME, Stover NB, Johnsen S, et al, International Society for Clinical Electrophysiology in Vision, Padua, Italy
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Lectures

• SD-OCT of Mice and Men. 
  Coordes Conference, UCSF
• Retinitis Pigmentosa. 
  Foundation Fighting Blindness, Visions Conference
• The Advantages of Hand-held sdOCT for Studying Retinal Degeneration in Infants and Animal Models. 
  National Eye Institute
• Adaptive Optic Imaging using the RTx1. 
  Oregon Ophthalmic Alumni Association
• Inherited Diseases of the Retina. 
  Casey Eye Institute, Resident Basic Science Series
• Genetic Diseases of the Retina. 
  Casey Eye Institute, Resident OKAP Review
• The Importance of Genetic Testing. 
  Foundation Fighting Blindness, Chapter Meeting
• Basics of Vision Screening. 
  Interdisciplinary Community Health and Education Exchange
• Fundamentals of the Electroretinogram. 
  Casey Eye Institute, Resident Lecture Series
• Imaging Techniques for Posterior Segment Conundrums. 
  Oregon Ophthal. Alumni Assoc
• Retinitis Pigmentosa – Have we made any progress? 
  Casey Eye Institute Grand Rounds
• Retinitis Pigmentosa. 
  Foundation Fighting Blindness, Portland Vision Seminar
• Genetic Diseases of the Retina. 
  Casey Eye Institute, Resident OKAP Review
• Common Inherited Genetic Diseases of the Retina. 
  Oregon Academy of Ophthalmology
• New Mouse Models of Retinal Degeneration. 
  Retina Foundation of the Southwest
• Fundamental Concepts of the ERG. 
  Baylor Department of Ophthalmology, Basic Science Series
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