MarkELinskeyMD

PubMed

• 202 citations
  The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline.
  Timothy C. Ryken, Michael W. McDermott, Paula D. Robinson, Mario Ammirati, David W. Andrews
  Journal of Neuro-Oncology. 2010-01-01
• 622 citations
  Response assessment criteria for brain metastases: proposal from the RANO group
  Nan Lin, Eudocia Q. Lee, Hidefumi Aoyama, Igor J. Barani, Daniel P. Barboriak
  The Lancet. Oncology. 2015-06-01
• 98 citations
  Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group
  Nan Lin, Eudocia Q. Lee, Hidefumi Aoyama, Igor J. Barani, Brigitta G. Baumert
  The Lancet. Oncology. 2013-09-01

Journal Articles

• Failing to detect occult blood.  
  Hovsepian DM, Linskey ME, Fedorak R, Ann Intern Med 1986; 105:471
• Surgery for acoustic neurinomas.  
  Linskey ME, Lunsford LD, J Neurosurg 1991; 75:497
• Gamma knife treatment and collateral damage.  
  Linskey ME, Johnstone P, J Neurosurg 2003; 99:938-940
• Which cavernous sinus aneurysms should be treated?  
  Linskey ME, Sekhar LN, J Neurosurg 1993; 78:1008-1009
• Correspondence, “To the Editor” on Piovesan EF, Teive HG, Howacs PA, Della Coletta MV, Werneck LC, Silberstein SD. An open study of botulinum-A toxin treatment of trig...  
  Zakrzewska, JM, Cohen J, Brown J, Alksne J, Gemillion H, Linskey M, Sirois D, Pollock B, Neurology. 2005 Oct 25; 65(8): 1306-8. Neurology. 2006 May; 66:1458-1459
• Neural Stem/Progenitors and Glioma Stem-like Cells Have Differential Sensitivity to Chemotherapy (letter response).  
  Gong X, Schwartz PH, Linskey ME, Bota DA, Neurology 2011; 77:e135-136
• In-Vivo Optical Imaging of Cerebral Ischemia and Perfusion in a Brain Injury Model.  
  Abookasis D, Mathews MS, Lay C, Binder DK, Frostig RD, Linskey ME, Tromberg BJ, Department of Defense Advance Technology for Applications, St. Petersburg Beach, FL
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Books/Book Chapters

• Youmans Textbook of Neurological Surgery. Vol 3. 
  Chapter: General and historical considerations of radiotherapy and radiosurgery 
  Page 2547 - 2555Linskey ME, Kuo JEditors: Winn HR.Saunders, PhiladelphiaEdition 6,
• Atlas of Neurosurgical Techniques. 
  Chapter: Malignant tumors of the anterior cranial base 
  Page 588 - 598Hanna E, Linskey M, Pieper DEditors: Sekhar Laligam N, Fessler Richard G.Thieme, New York
• Atlas of Neurosurgical Techniques. Brain. 
  Chapter: Repair of cranial nerve VII 
  Page 881 - 885Danner C, Dornhoffer J, Linskey MEditors: Sekhar Laligam N, Fessler Richard G.Thieme, New York
• Essentials of Surgical Specialties. 
  Chapter: Neurosurgery: Diseases of the nervous system 
  Page 331 - 395Linskey MEEditors: Lawrence Peter F.Lippincott Williams & Wilkins, PhiladelphiaEdition 3,
• Clinical Endocrine Oncology. 
  Chapter: Cavernous sinus hemangiomas 
  Page 318 - 324Linskey MEEditors: Hay Ian D, Turner H, Wass John AH.Blackwell Scientific Publications, OxfordEdition 2,
• Orofacial Pain. 
  Chapter: Trigeminal neuralgia 
  Page 119 - 134Zakrzewska JM, Linskey MEditors: Zakrzewska JM.Oxford University Press, London
• Trigeminal Neuralgia. 
  Chapter: Differential diagnosis of trigeminal neuralgia: Look alike diseases and atypical trigeminal neuralgia 
  Page 74 - 86Linskey ME, Jannetta PJEditors: Jannetta PJ.Oxford University Press, London
• Trigeminal Neuralgia. 
  Chapter: Stereotactic radiosurgery for trigeminal neuralgia 
  Page 169 - 191Linskey MEEditors: Jannetta PJ.Oxford University Press, London
• Youmans Textbook of Neurological Surgery. Vol 2. 
  Chapter: Trigeminal neuralgia: Diagnosis and non-operative management 
  Page 1776 - 1780Mathews MS, Binder DK, Linskey MEEditors: Winn HR.Saunders, PhiladelphiaEdition 6,
• Guiding Neurosurgery by Evidence. 
  Chapter: Evidence-based medicine for neurosurgeons: Introduction and methodology 
  Page 1 - 53Linskey MEEditors: Pollock BE.Prog Neurol Surg, Basel, Karger
• Current and Future Management of Brain Metastasis. 
  Chapter: Epidemiology of brain metastases 
  Page 13 - 29Alexandru D, Bota D, Linskey MEEditors: Lunsford LD.Prog Neurol Surg, Basel, KargerEdition 25,
• Controversies in Neurosurgery. 
  Chapter: Stereotactic radiosurgery for small AVM 
  Linskey MEEditors: Al-Mefty O, Origitano TC, Harkey L.Thieme, New YorkEdition 2,
• Controversies in Stereotactic Radiosurgery. 
  Chapter: Stereotactic radiosurgery for single metastatic brain tumors 
  Linskey MEEditors: Sheehan J, Gerszten P.Thieme, New York
• The Technique and Evaluation of Contemporary Radiosurgery. 
  Chapter: Commentary on Foote RL, Pollock BE, Stafford SL. Radiosurgery of chordomas, glomus tumors, and malignant skull base tumors 
  Page 304 - 308Linskey MEEditors: Pollock BE.Futura Publishing, Co, Mount Kiscoe, NY
• The Technique and Evaluation of Contemporary Radiosurgery. 
  Chapter: Radiosurgery of chordomas, glomus tumors, and malignant skull base tumors 
  Page 304 - 308Linskey MEEditors: Pollock BE.Futura Publishing, Co, Mount Kiscoe, NY
• Yearbook of Neurology and Neurosurgery 2003. 
  Chapter: The preferred management for patients with nonvestibular schwannomas 
  Page 180 - 182Linskey MEEditors: Gibbs SR, Verma A.Mosby, Baltimore
• Yearbook of Neurology and Neurosurgery 2005. 
  Chapter: Intellectual prognosis of the Dandy-Walker malformation in children: The importance of vermian lobulation 
  Page 298 - 299Linskey MEEditors: Gibbs SR, Verma A.Mosby, Baltimore
• Yearbook of Neurology and Neurosurgery 2005. 
  Chapter: Predictors of death in pediatric patients requiring cerebrospinal fluid shunts 
  Page 299 - 300Linskey MEEditors: Gibbs SR, Verma A.Mosby, Baltimore
• Benign Cerebral Gliomas. Neurosurgical Topic Series. 
  Chapter: The developmental biology of glial cells and its relation to the study of glioma biology 
  Page 13 - 57Linskey MEEditors: Apuzzo MLJ.American Association of Neurological Surgeons, Park Ridge
• Stereotactic Radiosurgery Update. 
  Chapter: Stereotactic radiosurgery for acoustic nerve sheath tumors 
  Page 321 - 334Linskey ME, Lunsford LD, Flickinger JCEditors: Lunsford LD.Elsevier, New York
• Acoustic Neuroma. 
  Chapter: Stereotactic radiosurgery for acoustic nerve sheath tumors 
  Page 279 - 287Lunsford LD, Linskey ME, Flickinger JCEditors: Tos M, Thomsen J.Kugler Publications, New York
• NIH Consensus Development Conference: Acoustic Neuroma. 
  Chapter: Stereotactic radiosurgery for acoustic tumors 
  Page 11 - 13Lunsford LD, Linskey ME, Flickinger JCEditors: Eldridge R.National Institutes of Health, Bethesda
• Surgery of Cranial Base Tumors. 
  Chapter: Cerebral revascularization in cranial base surgery 
  Page 45 - 68Linskey ME, Sekhar LN, Sen CEditors: Sekhar LN, Janecka IP.Raven Press, Ltd, New York
• Stereotactic Radiosurgery. 
  Chapter: Skull base radiosurgery 
  Page 175 - 188Kondziolka D, Lunsford LD, Linskey ME, Flickinger JCEditors: Alexander III E, Loeffler JS, Lunsford LD.McGraw Hill, Inc, New York
• Stereotactic Radiosurgery. 
  Chapter: Animal models in radiosurgery 
  Page 51 - 64Kondziolka D, Linskey ME, Lunsford LDEditors: Alexander III E, Loeffler JS, Lunsford LD.McGraw Hill, Inc, New York
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Abstracts/Posters

• MR susceptibility weighted imaging (SWT) complements conventional contrast enhanced imaging for melanoma Gamma Knife radiosurgery planning.
  Kuo JV, Huang J, Linskey ME, American Society for Radiation Oncology, Orlando FL
• Association of prognostic magnetic resonance imaging parameters and molecular biomarkers in primary glioblastoma multiforme.
  Kong XT, Fu BD, Du S, Hasso AN, Linskey ME, Bota D, Society for Neuro-Oncology, Washington, DC
• How accurately can we predict the survival of patients with cancer?
  Kondziolka D, Parry PV, Lunsford LD, Flickinger JC, Rakfal S, Arai Y, Loeffler JS, Rush S, Knisely J, Sheehan J, Friedman W, Tarhini A, Francis L, Ahluwalia M, Linskey..., American Academy of Neurological Surgeons, Chatham/Cape Cod, MA
• Commonly utilized chemotherapy treatments cause severe hippocampal neaural stem cell loss and damage the dendritic spines on hippocampal neurons.
  Gong X, Kakar G, Di K, Andres A, Linskey M, Bota D, American Academy of Neurology, New Orleans, LA
• CHaracterization of two tumor populations in GBM cell line U251 revealed the advantage of GBM intra-tumoral heterogeneity.
  Hu Y, Chaturbedi A, Ru N, Linskey ME, Zhou YH, Asian Society for Neuro-Oncology, Taipei
• Symbiosis betweeen tumor subpopulations underlies the malignant behaviour and recurrent nature of glioblastoma multiforme.
  Hu Y, Chaturbedi A, Nelson J, Linskey ME, Zhou YH, Society for Neuro-Oncology, Orange County, CA
• EGF containing fibulin-like extracellular matrix protein 1 suppresses gliblastoma cell growth in vivo.
  Hu Y, Chaturbedi A, Hamamura M, Linskey ME, Zhou YH, Society for Neuro Oncology, Orange Country, GA
• Integrative analysis of genome expression and protein profiling reveals multiple core pathways effected by EFEMP1 in glioma.
  Hu Y, Linskey M, Zhou YH, Society for Neuro Oncology, Orange County, GA
• Lack of concordance between IDH 1 mutation and 1p 19q deletion in gliomas.
  Chaturbedi A, Wong A, Fatuyi R, Linskey ME, Yu L, Zhou YH, SOciety for Neuro-Oncology, Orange County, CA
• TRIM 11 is a novel and specific glioma stem-like cell marker that also plays a role in glioma biology through the EGFR pathway.
  Di K, Linskey ME, Bota DA, Society for Neuro-Oncology, Orange County, CA
• Acute DNA-targeted chemotherapy administration causes hippocampal neural stem cell mitochondrial damage and in vivo apoptotic cell death.
  Gong X, Kankar G, Di K, Reeves A, Linskey ME, Bota DA, Society for Neuro-Oncology, Orange County, CA
• Recurrent glioblastoma multiforme: Implications of nonenhancing lesions on bevacizumab treatment.
  Alexandru D, Kim RC, Bota DA, Linskey ME, Society for Neuro-Oncology, Orange County, CA
• BCNU impregnated (Gliadel) chemotherapy-induced bone and scalp sarcoma.
  Alexandru D, Bota DA, Linskey ME, Society for Neuro-Oncology, Orange County, CA
• Trim 11 is a potential cancer stem cell marker in gliomas.
  Di K, Chaturbedi A, Linskey ME, Bota DA, COngress of Neurological Surgeons, Washington, DC
• Efficacy and Evolution of the Socioeconomic Fellowship of the Council of State Neurosurgical Societies.
  Hussain N, Benzil DL, Lobel DA, Linskey ME, Bloomgarden GM, Bingaman, W, Congress of Neurological Surgeons, Washington, DC
• Relationship between MR imaging and molecular biomarkers in glioblastoma multiforma.
  Kong XT, Fu BD, Linskey ME, Bota DA, American Neurological Association, San Diego, CA
• Efficacy and Evolution of the Socioeconomic Fellowship of the Council of State Neurosurgical Societies.
  Linskey ME, Benzil DL, Hussain N, Lobel DA, Bloomgarden GM, Bingaman, W, Western Neurosurgical Society, Kauai, HI
• Phase II clinical trial of bortezomib and bevacizumab combination in recurrent glioblastoma.
  Bota DA, Eroglu Z, Reardon DA, Fu BD, Norfleet J, Desjardins A, Linskey ME, Peters K, Friedman HS, Vredenburgh JJ, American Society of Clinical Oncology, Chicago, IL
• Malignant transformation of skull base chordoma into osteosarcoma after photon radiation.
  Chaturbedi A, Linskey ME, Kim R, Hasso A, North American SKull Base Society, Scottsdale, AZ
• Modeling prognosis for glioma patients with standardized quantification of gene expression for a select set of genes.
  Zhou YH, Hess K, Vinay RR, Yu L, Liu L, Yung WKA, Linskey ME, Society for Neuro-Oncology, MOntreal, Canada
• PAX6 expression in glioma: friend or foe?
  Zhou YH, Hu Y, Pioli P, Rajneesh K, Limoli CL, Yu L, Hess K, Linskey ME, Society for Neuro-Oncology, MOntreal, Canada
• Extracellular EFEMP1 129. blocks Akt phosphorylation and decreases EGFR in glioma cells.
  Pioli PD, Linskey ML, and Zhou YH, Society for Neuro-Oncology, MOntreal, Canada
• EFEMP1 expression in glioma: friend or foe?
  Hu Y, Pioli PD, Siegel E, Ro DI, Mathews MS, Hsu N, Milani SN, Hamamura M, Yu L, Linskey ME, Zhou Y-H, Society for Neuro-Oncology, MOntreal, Canada
• Retrospective study of bevacizumab and etoposide combination chemotherapy in patients with recurrent malignant gliomas who failed bevacizumab.
  Fu DB, Bota DA, Linskey ME, Society for Neuro-Oncology, MOntreal, Canada
• The access to specialized neuro-oncological treatment for adult Hispanic brain tumor patients: Findings from a single institution retrospective study.
  Nasheed M, Linskey ME, Bota DA, Society for Neuro-Oncology, MOntreal, Canada
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Lectures

• Clinical trial design. 
  Congress of Neurological Surgeons, San Francisco, CA
• Trigeminal neuralgia. 
  TNA- The Facial Pain Association National Conference, San Diego, CA
• Role for guidelines in the treatment of facial pain. 
  New Orleans, LA
• Growth and management of neurosurgical practices: Academic practice. Breakfast Seminar 224. Business of Neurosurgery II. 
  New Orleans, LA
• Microvascular decompression for trigeminal neuralgia. 
  Department of Neurological Surgery, UC Irvine Orange, CA
• Neurosurgery advances for malignant brain tumors. 
  Multiple Locations, 2012, 2013
• Newer treatments for brain metastases. Brain Metastasis. 
  Multiple Locations, 2012
• Gamma Knife stereotactic radiosurgery. 
  Chao Family Comprehensive Cancer Center
• Lessons learned for 8 years as a member of the Trigeminal Neuralgia. 
  Orange Country Trigeminal Neuralgia Association, Orange, CA
• Biomedical Engineering Course 240: Introduction to clinical medicine – Bioengineering and neurosurgery. 
  Henry Samueli School of Engineering, UC Irvine, Irvine, CA
• Radiosurgery versus surgery for vestibular schwannomas – pro’s and cons 
  Leksell Gamma Knife Socity, Sydney, Australia
• Case studies in benign tumor radiosurgery. 
  Leksell Gamma Knife Socity, Sydney, Australia
• The radiobiology of radiosurgery for benign tumors. 
  Leksell Gamma Knife Socity, Sydney, Australia
• Microsurgical approaches to vestibular schwannomas. 
  Otolaryngology UC Irvine Head & Neck Surgery
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Other

• Handbook of Neurosurgery (Review), 7th Edition. 
  Owen CM, Linskey ME, J Trauma 2010; 69:475
• The role of radiosurgery to the tumor bed after resection of brain metastases. 
  Linskey ME, Neurosurgery
• Retrospective analysis of imaging techniques for treatment planning and monitoring of obliteration for gamma knife treatment of cerebral arteriovenous malformation. 
  Linskey ME, Neurosurgery 2013; 71:899
• Efficacy and safety of local versus general anesthesia in stereotactic biopsies: A matched-pairs cohort study. 
  Linskey ME, J Neurosurg Anesthesiol
• Prediction of minimally conscious state with somatosensory evoked potentials in long-term unconscious patients after traumatic brain injury. 
  Linskey ME, J Trauma Acute Care Surg 2012; 72:1029-1030
• Results of the prospective, randomized multicenter trial of a biosynthesized cellulose versus commercially available grafts for repair of dural defects. 
  Linskey ME, Neurosurgery 2011; 69:1103-1104
• Outpatient brain tumor surgery and spinal decompression: A prospective study of 1003 patients. 
  Linskey ME, Neurosurgery 2011; 69:126-127
• Teleconferencing using multimedia messaging service (mms) for long-range consultation of patients with neurosurgical problems in an acute situation. 
  Linskey ME, J Trauma Acute Care Surg. 2008 64(2): 365
• Endoscopic endonasal partial middle turbinectomy approach: adaptability of the procedure in a cadaveric study and in surgery for different sphenoid sinus and skull bas... 
  Linskey ME, Skull Base: An Interdisciplinary Approach. 2006 16(1): 13
• Ameloblastic carcinoma arising from anterior skull base. 
  Linskey ME, Skull Base 2005 15(4): 273
• Cadaveric dissections based on observations of injuries to the temporal bone structures following head trama. 
  Linskey ME, Skull Base 2005, 15(2), pp 99-107
• Brain tumors and cell phones. Commentary on Muscat JE, Malkin MG, Thompson S, et al. Handheld cellular telephone use and risk of brain cancer. 
  Linskey ME, JAMA 2000; 284:3001-3007 and Inskip
• Practice Guidelines-Why Bother? IOM, MedPAC and Others Call for Evidence-Based Quality Care. 
  Linskey ME, AANS Bulletin, 2005; 14(1): 17
• Trigeminal Neuralgia. 
  Linskey ME, American College of Physicians (ACP), Physician’ Information and Education Resource (PIER) module
  http://pier.acponline.org/physicians/diseases/d625/d625-pdf.html
• Locked out. 
  Linskey ME, AANS Neurosurgeon 2012; 21(3)
• First cranial module for N2QOD. Tumor News. 
  Linskey ME, AANS/CNS Section on Tumors Newsletter, Spring 2012; 3
• Tumor guidelines report. Tumor News. 
  Linskey ME, Kalkanis S, AANS/CNS Section on Tumors Newsletter, Spring 2009; 10
• CNS consensus sessions and the annual meeting: We are listening. 
  Selden NR, Rezai AR, Rodts GE, Linskey ME, Asher AL, Congress Quarterly, Fall 2008; 10-11
• Tumor Section Develops Evidence-Based Guidelines. 
  Linskey ME, AANS/CNS Section on Tumors Newsletter
• Guidelines committee update Tumor News. 
  Linskey ME, AANS/CNS Section on Tumors Newsletter.
• Re-engineering the neurosurgery guidelines effort: A critical need in preparation for pay-for-performance. 
  Linskey ME, Neurosurgery News 2005; 6(5): 4
• Practice guidelines: Current status in neurosurgery. 
  Linskey ME, Neurosurgery News 2005; 6(4): 6-8
• Practice guidelines-Why bother? 
  Linskey ME, Neurosurgery News, 2005; 6(3): 12-14
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