MarkEricKohlerMDPhD

Pediatric Hematologic Oncology

Instructor of Pediatrics, Children's Hospital Colorado University of Colorado

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Office
Children's Hospital Colorado
13123 E 16th Ave
Aurora, CO 80045
Phone+1 720-777-6892

Fax+1 720-777-7346

National Capital ConsortiumFellowship, Pediatric Hematology/Oncology, 2014 - 2018
Johns Hopkins UniversityFellowship, Pediatric Hematology/Oncology, 2014 - 2018
Johns Hopkins UniversityResidency, Pediatrics, 2011 - 2014
Medical College of WisconsinClass of 2011
Medical College of WisconsinPhD, Immunology , 2004 - 2009
Rockhurst UniversityBS, Biology, Chemistry , Summa Cum Laude, 1997 - 2001

Crystal Mackall Award for Pediatric Oncology Reserch Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, 2018
Abstract Achievement Award American Society of Hematology, 2018

PubMed

1171 citations
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
Adrienne H. Long, Waleed Haso, Jack F. Shern, Kelsey Wanhainen, Meera Murgai
Nature Medicine. 2015-06-01
19 citations
Does lineage plasticity enable escape from CAR-T cell therapy? Lessons from MLL-r leukemia
Wenjuan Liao, M. Eric Kohler, Terry J. Fry, Patricia Ernst
Experimental Hematology. 2021-08-01
181 citations
Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell–depleted stem cell transplantation
Nirali N. Shah, Kristin Baird, Cynthia Delbrook, Thomas A. Fleisher, Mark E. Kohler
Blood. 2015-01-29

Books/Book Chapters

The Harriet Lane Handbook
Chapter: Chpt. 22: Oncology
Page 523 - 539M. Eric KohlerEditors: B. Enghorn and J. Flerlage.Elsevier SaundersEdition 20,2015

Abstracts/Posters

A Direct Comparison of the In Vivo Efficacy and In Vitro Signaling of Chimeric Antigen Receptors and Endogenous T Cell Receptors.
Kohler, ME, Yang, Y, Sepulveda, G, Fry, TJ., American Society of Hematology 59th Annual Meeting, Atlanta, GA, 12/2017
Effect of Chronic Endogenous Antigen Stimulation on CAR T Cell Persistence and Memory Formation
Yang, Y, Kohler, ME, Fry, TJ, American Society of Hematology 59th Annual Meeting, Atlanta, GA, 12/2017
Modeling Retreatment of Acute Lymphoblastic Leukemia with Anti-CD19 Chimeric Antigen Receptor T Cell Therapy
Yang, Y, Kohler, ME, Fry, TJ, American Society of Hematology 58th Annual Meeting, San Diego, CA, 12/2016
Induction of “Stemness” Genes in CD8 T Cells After Vaccination of Tumor-Free Mice with a Cell-Based Vaccine
Kohler, ME, Hallet, WHD, Chen, QR, Khan, J, Johnson, BD, Orentas, RJ., AACR Tumor Immunology: New Perspectives, Miami, FL, 12/2008
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Health Crisis Has Created a Potential $250 Billion Telehealth OpportunitySeptember 16th, 2020
CloudMD Is My TeleHealth StockApril 30th, 2020
Hyundai Hope on Wheels Presents Children's Hospital Colorado with $200,000 Hyundai Young Investigator Grant to Support Pediatric Cancer ResearchSeptember 6th, 2019

Paul Calabresi Clinical Scholars AwardUniversity of Colorado Cancer Center2019–2021
Defining the signal transduction pathways of Chimeric Antigen Receptors (CAR) as a means to increase the efficacy of CAR T cell therapy for pediatric leukemiasHyundai Hope on Wheels2019–2021
CD99 targeting CAR T cells as a novel therapy for H3K27M mutant DIPGCancer League of Colorado2019–2020