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Office
2412 N John B Dennis Hwy
Kingsport, TN 37660Phone+1 423-578-4364Fax+1 423-578-4372- Is this information wrong?
Education & Training
- University of Kentucky College of MedicineFellowship, Surgical Retina and Vitreous, 2011 - 2013
- University of Kentucky College of MedicineResidency, Ophthalmology, 2008 - 2011
- University of Kentucky Albert B. Chandler HospitalPost-Doctoral Fellowship, 2006 - 2008
- NYU Grossman School of MedicineInternship, Transitional Year, 2005 - 2006
- New York University School of MedicineClass of 2005
- Emory UniversityB.S., Biology/Chemistry, 1994 - 1998
Certifications & Licensure
- KY State Medical License 2011 - 2025
- TN State Medical License 2018 - 2024
- VA State Medical License 2018 - 2024
- American Board of Ophthalmology Ophthalmology
Awards, Honors, & Recognition
- BrightFocus Award for Macular Degeneration Research 2018
- Ophthalmologist of the Year Award Kentucky Academy of Eye Physicians, 2017
- Young Physician-Scientist Award ASCI, 2016
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Clinical Trials
- A Phase I Open Label Dose Escalation Trial of RNA-144101 in the Treatment of Geographic Atrophy Start of enrollment: 2011 Mar 01
Publications & Presentations
PubMed
- 530 citationsCorneal avascularity is due to soluble VEGF receptor-1Balamurali K. Ambati, Miho Nozaki, Nirbhai Singh, Atsunobu Takeda, P. Jani
Nature. 2006-10-26 - 695 citationsSequence- and target-independent angiogenesis suppression by siRNA via TLR3Mark E. Kleinman, Kiyoshi Yamada, Atsunobu Takeda, Vasu Chandrasekaran, Miho Nozaki
Nature. 2008-04-03 - 2059 citationsProgenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1Daniel J. Ceradini, Anita R Kulkarni, Matthew J. Callaghan, Oren M. Tepper, Nicholas Bastidas
Nature Medicine. 2004-07-04
Journal Articles
- Therapeutic Approaches to Histone Reprogramming in Retinal DegenerationBerner AK, Kleinman ME, Adv Exp Med Biol, 1/1/2016
- Vision Loss in Juvenile Neuronal Ceroid LipofuscinosisOuseph M, Kleinman ME, Wang Q, Ann N Y Acad Sci, 1/1/2016
- Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 InflammasomeGelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Nunez G, Georg..., Cell Reports, 1/1/2015
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Books/Book Chapters
Abstracts/Posters
- Epigenetic regulation of autophagy by histone deacetylases in retinal pigment epithelium.Dubey S, Lou D, Jung K, Roney J, Brown J, Mohan K, Kleinman ME, Annual ARVO Meeting, Baltimore, MD, 1/1/2017
- Neutralization of IFNAR1 prevents histone deacetylase inhibitor induced retinal pigment epithelium cell death.Jung K, Mohan K, Prajapati SC, Dubey S, Lou D, Roney J, Brown J, Kleinman ME, Annual ARVO Meeting, Baltimore, MD, 1/1/2017
- Safety and efficiency of CRISPR-Cas9 gene editing in the retinal pigment epithelium.Kleinman ME, Dubey S, Jung K, Roney J, Lou D, Brown J, Mohan K, Annual ARVO Meeting, Baltimore, MD, 1/1/2017
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Lectures
- Current Therapies for AMD.Baltimore, MD, 2013; Denver, CO, 2014 - 1/1/2014
- Update on AMD Research.1/1/2013
- Employing Ocular Electrophysiology in Your Practice.1/1/2013
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