Skip to main content
Mark Greene, MD, Internal Medicine, Philadelphia, PA

MarkIGreeneMD

Internal Medicine Philadelphia, PA

Adult Clinical & Laboratory Immunology

Professor, Pathology & Laboratory Medicine, Perelman School of Medicine

Dr. Greene is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

  • Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
  • Connect with colleagues in the same hospital or clinic.
  • Read the latest clinical news, personalized to your specialty.

See Dr. Greene's full profile

Already have an account?

  • Office

    3400 Spruce St
    Philadelphia, PA 19104
    Phone+1 215-662-6503

Summary

  • Dr. Mark Greene is a healthcare professional based in Philadelphia, PA, specializing in Internal Medicine . He completed his education at the University of Manitoba, including a PhD in Immunology. Dr. Greene serves as the John Eckman Professor of Medical Science at the Hospital of the University of Pennsylvania. His research experience includes work with proto-oncogene proteins, and he has several publications focusing on HER2 cancer therapy and structural immunology, with notable citations. Over the years, he has received several honors such as the Fellow of Lincoln College from Oxford University and the BCRF Breast Cancer Research Award. He discovered targeted therapy of p185Neu and the therapy of HER2 tumors with single or dual targeted monoclonal. His discovery of AHNP ( based on the crystal structure of the antiHER2 monoclonal) and is able to be coupled to different molecules to enter HER2 transformed cells

Education & Training

  • University of Manitoba
    University of ManitobaPhD, Immunology, 1973 - 1977
  • University of Manitoba
    University of ManitobaClass of 1972
  • University of Manitoba
    University of ManitobaBachelor's, 1966 - 1968

Certifications & Licensure

  • PA State Medical License
    PA State Medical License 1985 - 2024
  • MA State Medical License
    MA State Medical License 1975 - 2023
  • Internal Medicine
    Fellow of the Royal College of MedicineInternal Medicine

Awards, Honors, & Recognition

  • Fellow Lincoln College Oxford University, 2010
  • Geurin Chair Cedars-Sinai, 2010
  • Dsc, Honoris causa, MAN 2009
  • Join now to see all

Publications & Presentations

PubMed

Journal Articles

  •  
    Zhang, H., Lam, L., Nagai, Y., Zhu, Z., Chen, X., Ji, MQ, and Greene, MI, Oncoimmunology, 1/17/2017
  • Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions  
    Bin Dhuban K, d'Hennezel E, Nagai Y, Xiao Y, Shao S, Istomine R, Alvarez F, Ben-Shoshan M, Ochs H, Mazer B, Li B, Sekine C, Berezov A, Hancock W, Torgerson TR, Greene ..., Sci Immunol, 1/1/2017
  • Atomic Description of the Immune Complex involved in Heparin-Induced Thrombocytopenia (HIT)  
    Cai Z, Yarovoi SV, Zhu Z, Rauova L, Hayes V, Lebedeva T, Liu Q, Poncz M, Arepally G, Cines DB, and Greene MI, Nature Communications, 1/22/2015
  • Join now to see all

Books/Book Chapters

  • Join now to see all

Other

  • Suppressor T cell and their factors in the S1509a tumor bearing A/Jax mouse host. Ph.D. Thesis 
    Greene, M.I., University of Manitoba
    1/1/1977

Press Mentions

  • Dr. Peter Nowell, Who Helped Transform Cancer Research, Dies at 88
    Dr. Peter Nowell, Who Helped Transform Cancer Research, Dies at 88January 11th, 2017
  • Navidea Reports First Quarter 2016 Financial Results
    Navidea Reports First Quarter 2016 Financial ResultsMay 17th, 2016

Grant Support

  • Inhibition Of Heteromeric ERBB KinasesNational Cancer Institute2011–2012
  • Receptor Mediated Breast Cancer TherapyNational Cancer Institute2001–2012
  • Immune Chemistry And Therapeutic Features Of FOXP3National Institute Of Allergy And Infectious Diseases2008–2011
  • FOXP3 And Immune RegulationNational Institute Of Allergy And Infectious Diseases2008–2011
  • Administrative CoreNational Institute Of Allergy And Infectious Diseases2008–2011
  • Immunobiology Of P185 ReceptorNational Cancer Institute1992–2011
  • Receptor-Mediated Effects On Oligodendrocyte Phenotype And DiseaseNational Institute Of Neurological Disorders And Stroke2007
  • Viral Receptors Of The Visual Nervous SystemNational Institute Of Neurological Disorders And Stroke2004–2007
  • Training In Cancer ImmunopathobiologyNational Cancer Institute2003–2007
  • Receptor Mediated Efffects On Oligodendrocyte PhenotypeNational Institute Of Neurological Disorders And Stroke2004–2006
  • Novel Approaches To Cancer TherapyNational Cancer Institute2002–2005
  • Receptor-Mediated Effects On Oligodendrocyte PhenotypeNational Institute Of Neurological Disorders And Stroke2003
  • Core--StructuralNational Cancer Institute2002
  • Immunobiology Of Antireceptor Receptor InteractionsNational Eye Institute1991–2001
  • Receptor/Ligand Interactions Of Developing OligodendrocytesNational Institute Of Neurological Disorders And Stroke1996–2000
  • Training Program In Immunobiology Of The EyeNational Eye Institute1991–2000
  • Molecular Regulation Of T Cell Apoptosis &AutoimmunityNational Institute Of Allergy And Infectious Diseases1994–1996
  • Molecular Regulation Of Neoplastic And Normal GrowthNational Cancer Institute1992–1996
  • Immunobiology Of Antireceptor-Receptor InteractionsNational Eye Institute1995
  • Cellular And Molecular Regulation Of Ocular ImmunityNational Eye Institute1993–1995
  • Facstar-Plus Dual Laser Flow CytometerNational Center For Research Resources1993
  • Characterization Of The Mammalian Reovirus ReceptorNational Eye Institute1989–1993
  • Cellular &Molecular Regulation Of Ocular ImmunityNational Eye Institute1986–1992
  • Immunobiology Of Normal And Neoplastic LymphocytesNational Cancer Institute1986–1991
  • Immunobiology Of Antireceptor-Receptor InteractionsNational Institute Of Allergy And Infectious Diseases1986–1990
  • Characterization Of The Mammalian Reovirus ReceptorNational Institute Of Allergy And Infectious Diseases1986–1988
  • Manipulation Of Regulatory T Cell SpecificitiesNational Cancer Institute1986–1988
  • Immunobiology Of Normal &Transformed CellsNational Cancer Institute1987
  • Suppressor T Cells In Hapten Specific ImmunityNational Institute Of Allergy And Infectious Diseases1985

Research History

  • Ph.DImmunology/immunochemistry1973 - 1977